JP2021526791A5 - - Google Patents

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Publication number
JP2021526791A5
JP2021526791A5 JP2020567550A JP2020567550A JP2021526791A5 JP 2021526791 A5 JP2021526791 A5 JP 2021526791A5 JP 2020567550 A JP2020567550 A JP 2020567550A JP 2020567550 A JP2020567550 A JP 2020567550A JP 2021526791 A5 JP2021526791 A5 JP 2021526791A5
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JP
Japan
Prior art keywords
classification
allele
nucleic acid
computer
alleles
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020567550A
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English (en)
Japanese (ja)
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JP2021526791A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/035214 external-priority patent/WO2019236478A1/en
Publication of JP2021526791A publication Critical patent/JP2021526791A/ja
Publication of JP2021526791A5 publication Critical patent/JP2021526791A5/ja
Priority to JP2023199814A priority Critical patent/JP2024015059A/ja
Priority to JP2025185468A priority patent/JP2026012397A/ja
Pending legal-status Critical Current

Links

JP2020567550A 2018-06-04 2019-06-03 セルフリー核酸の細胞起源を決定するための方法およびシステム Pending JP2021526791A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023199814A JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862680301P 2018-06-04 2018-06-04
US62/680,301 2018-06-04
PCT/US2019/035214 WO2019236478A1 (en) 2018-06-04 2019-06-03 Methods and systems for determining the cellular origin of cell-free nucleic acids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023199814A Division JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム

Publications (2)

Publication Number Publication Date
JP2021526791A JP2021526791A (ja) 2021-10-11
JP2021526791A5 true JP2021526791A5 (enExample) 2022-06-10

Family

ID=67138034

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020567550A Pending JP2021526791A (ja) 2018-06-04 2019-06-03 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2023199814A Withdrawn JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A Pending JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023199814A Withdrawn JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A Pending JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

Country Status (4)

Country Link
US (1) US20190385700A1 (enExample)
EP (1) EP3802878A1 (enExample)
JP (3) JP2021526791A (enExample)
WO (1) WO2019236478A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2927607C (en) 2009-12-10 2021-04-06 Royal Bank Of Canada Synchronized processing of data by networked computing resources
US9940670B2 (en) * 2009-12-10 2018-04-10 Royal Bank Of Canada Synchronized processing of data by networked computing resources
EP3731959B1 (en) 2017-12-29 2025-10-08 Clear Labs, Inc. Automated priming and library loading device
CA3089756A1 (en) 2018-01-29 2019-08-01 St. Jude Children's Research Hospital, Inc. Method for nucleic acid amplification
CN120193081A (zh) 2018-07-23 2025-06-24 夸登特健康公司 用于通过肿瘤分数和覆盖率调整肿瘤突变负荷的方法和系统
US12437839B2 (en) 2019-05-03 2025-10-07 Ultima Genomics, Inc. Methods for detecting nucleic acid variants
KR20220031860A (ko) 2019-05-03 2022-03-14 울티마 제노믹스, 인크. 핵산 변이체를 검출하는 방법
EP4103745A4 (en) * 2020-02-10 2024-03-13 Bioskryb Genomics, Inc. Phi29 mutants and use thereof
EP4118653B1 (en) * 2020-03-11 2024-07-17 Guardant Health, Inc. Methods for classifying genetic mutations detected in cell-free nucleic acids as tumor or non-tumor origin
WO2021194837A1 (en) * 2020-03-26 2021-09-30 Memorial Sloan Kettering Cancer Center Systems and methods for distinguishing pathological mutations from clonal hematopoietic mutations in plasma cell-free dna by fragment size analysis
CN120502365A (zh) * 2020-04-21 2025-08-19 赫孚孟拉罗股份公司 具有单分子传感器阵列的高通量核酸定序
WO2022046947A1 (en) * 2020-08-25 2022-03-03 Guardant Health, Inc. Methods and systems for predicting an origin of a variant
CN113257350B (zh) * 2021-06-10 2021-10-08 臻和(北京)生物科技有限公司 基于液体活检的ctDNA突变程度分析方法和装置、ctDNA性能分析装置

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582908B2 (en) 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
US20030017081A1 (en) 1994-02-10 2003-01-23 Affymetrix, Inc. Method and apparatus for imaging a sample on a device
ATE226983T1 (de) 1994-08-19 2002-11-15 Pe Corp Ny Gekoppeltes ampflikation- und ligationverfahren
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US6969488B2 (en) 1998-05-22 2005-11-29 Solexa, Inc. System and apparatus for sequential processing of analytes
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7501245B2 (en) 1999-06-28 2009-03-10 Helicos Biosciences Corp. Methods and apparatuses for analyzing polynucleotide sequences
WO2001023610A2 (en) 1999-09-29 2001-04-05 Solexa Ltd. Polynucleotide sequencing
EP2100971A3 (en) 2000-07-07 2009-11-25 Visigen Biotechnologies, Inc. Real-time sequence determination
ATE449186T1 (de) 2001-11-28 2009-12-15 Applied Biosystems Llc Zusammensetzungen und verfahren zur selektiven nukleinsäureisolierung
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
US7315019B2 (en) 2004-09-17 2008-01-01 Pacific Biosciences Of California, Inc. Arrays of optical confinements and uses thereof
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7282337B1 (en) 2006-04-14 2007-10-16 Helicos Biosciences Corporation Methods for increasing accuracy of nucleic acid sequencing
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
US11261494B2 (en) * 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
PL2893040T3 (pl) 2012-09-04 2019-05-31 Guardant Health Inc Sposoby wykrywania rzadkich mutacji i wariantu liczby kopii
CN111534580B (zh) 2013-12-28 2024-06-04 夸登特健康公司 用于检测遗传变异的方法和系统
US10801067B2 (en) * 2014-05-09 2020-10-13 Eurofins Lifecodexx Gmbh Detection of DNA that originates from a specific cell-type and related methods
CN107002122B (zh) * 2014-07-25 2023-09-19 华盛顿大学 确定导致无细胞dna的产生的组织和/或细胞类型的方法以及使用其鉴定疾病或紊乱的方法
WO2017181146A1 (en) 2016-04-14 2017-10-19 Guardant Health, Inc. Methods for early detection of cancer
GB201618485D0 (en) * 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence

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