JP2021526791A - セルフリー核酸の細胞起源を決定するための方法およびシステム - Google Patents

セルフリー核酸の細胞起源を決定するための方法およびシステム Download PDF

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JP2021526791A
JP2021526791A JP2020567550A JP2020567550A JP2021526791A JP 2021526791 A JP2021526791 A JP 2021526791A JP 2020567550 A JP2020567550 A JP 2020567550A JP 2020567550 A JP2020567550 A JP 2020567550A JP 2021526791 A JP2021526791 A JP 2021526791A
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nucleic acid
allele
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alleles
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JP2021526791A5 (enExample
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アリエル ジャイモビッチ，
アンドリュー ケネディ，
ジャスティン アイ． オーデガード，
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ガーダント ヘルス， インコーポレイテッド
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    • G16B30/10—Sequence alignment; Homology search
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    • C—CHEMISTRY; METALLURGY
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
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JP2020567550A 2018-06-04 2019-06-03 セルフリー核酸の細胞起源を決定するための方法およびシステム Pending JP2021526791A (ja)

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JP2023199814A JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

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US201862680301P 2018-06-04 2018-06-04
US62/680,301 2018-06-04
PCT/US2019/035214 WO2019236478A1 (en) 2018-06-04 2019-06-03 Methods and systems for determining the cellular origin of cell-free nucleic acids

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JP2023199814A Withdrawn JP2024015059A (ja) 2018-06-04 2023-11-27 セルフリー核酸の細胞起源を決定するための方法およびシステム
JP2025185468A Pending JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

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JP2025185468A Pending JP2026012397A (ja) 2018-06-04 2025-11-04 セルフリー核酸の細胞起源を決定するための方法およびシステム

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US (1) US20190385700A1 (enExample)
EP (1) EP3802878A1 (enExample)
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WO (1) WO2019236478A1 (enExample)

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CN120193081A (zh) 2018-07-23 2025-06-24 夸登特健康公司 用于通过肿瘤分数和覆盖率调整肿瘤突变负荷的方法和系统
US12437839B2 (en) 2019-05-03 2025-10-07 Ultima Genomics, Inc. Methods for detecting nucleic acid variants
KR20220031860A (ko) 2019-05-03 2022-03-14 울티마 제노믹스, 인크. 핵산 변이체를 검출하는 방법
EP4103745A4 (en) * 2020-02-10 2024-03-13 Bioskryb Genomics, Inc. Phi29 mutants and use thereof
EP4118653B1 (en) * 2020-03-11 2024-07-17 Guardant Health, Inc. Methods for classifying genetic mutations detected in cell-free nucleic acids as tumor or non-tumor origin
WO2021194837A1 (en) * 2020-03-26 2021-09-30 Memorial Sloan Kettering Cancer Center Systems and methods for distinguishing pathological mutations from clonal hematopoietic mutations in plasma cell-free dna by fragment size analysis
CN120502365A (zh) * 2020-04-21 2025-08-19 赫孚孟拉罗股份公司 具有单分子传感器阵列的高通量核酸定序
WO2022046947A1 (en) * 2020-08-25 2022-03-03 Guardant Health, Inc. Methods and systems for predicting an origin of a variant
CN113257350B (zh) * 2021-06-10 2021-10-08 臻和(北京)生物科技有限公司 基于液体活检的ctDNA突变程度分析方法和装置、ctDNA性能分析装置

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WO2019236478A1 (en) 2019-12-12
JP2024015059A (ja) 2024-02-01
JP2026012397A (ja) 2026-01-23
EP3802878A1 (en) 2021-04-14
US20190385700A1 (en) 2019-12-19

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