JP2016515390A5 - - Google Patents
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- Publication number
- JP2016515390A5 JP2016515390A5 JP2016506253A JP2016506253A JP2016515390A5 JP 2016515390 A5 JP2016515390 A5 JP 2016515390A5 JP 2016506253 A JP2016506253 A JP 2016506253A JP 2016506253 A JP2016506253 A JP 2016506253A JP 2016515390 A5 JP2016515390 A5 JP 2016515390A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- single nucleotide
- mrna expression
- gene
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000002773 nucleotide Substances 0.000 claims description 10
- 125000003729 nucleotide group Chemical group 0.000 claims description 10
- 102000054765 polymorphisms of proteins Human genes 0.000 claims description 5
- 101000605639 Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proteins 0.000 claims description 3
- 108020004999 messenger RNA Proteins 0.000 claims 7
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 4
- 206010017758 gastric cancer Diseases 0.000 claims 4
- 102000049555 human KRAS Human genes 0.000 claims 4
- 238000010837 poor prognosis Methods 0.000 claims 4
- 238000004393 prognosis Methods 0.000 claims 4
- 201000011549 stomach cancer Diseases 0.000 claims 4
- 230000004083 survival effect Effects 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 101000584612 Homo sapiens GTPase KRas Proteins 0.000 claims 2
- 101100086477 Homo sapiens KRAS gene Proteins 0.000 claims 2
- 101100291010 Homo sapiens MET gene Proteins 0.000 claims 2
- 101100190564 Homo sapiens PIK3CA gene Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 102000057421 human MET Human genes 0.000 claims 2
- 102000057995 human PIK3CA Human genes 0.000 claims 2
- 108010066733 mRNA (guanine(N7))-methyltransferase Proteins 0.000 claims 2
- 238000002271 resection Methods 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
- 230000035772 mutation Effects 0.000 description 5
- 102100030708 GTPase KRas Human genes 0.000 description 1
- 102100038332 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Human genes 0.000 description 1
- 102220198096 rs121913238 Human genes 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2013-0037336 | 2013-04-05 | ||
| KR1020130037336A KR101501826B1 (ko) | 2013-04-05 | 2013-04-05 | 위암에 대한 예후 예측 모형의 제조방법 |
| PCT/KR2014/002959 WO2014163445A1 (ko) | 2013-04-05 | 2014-04-07 | 위암에 대한 예후 예측 모형의 제조방법 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016515390A JP2016515390A (ja) | 2016-05-30 |
| JP2016515390A5 true JP2016515390A5 (enExample) | 2017-03-23 |
| JP6356217B2 JP6356217B2 (ja) | 2018-07-11 |
Family
ID=51658661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506253A Expired - Fee Related JP6356217B2 (ja) | 2013-04-05 | 2014-04-07 | 胃癌に対する予後予測模型の製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160040253A1 (enExample) |
| EP (1) | EP2982986B1 (enExample) |
| JP (1) | JP6356217B2 (enExample) |
| KR (1) | KR101501826B1 (enExample) |
| CN (1) | CN105431738B (enExample) |
| WO (1) | WO2014163445A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109923121B (zh) * | 2016-11-22 | 2022-12-23 | 武汉华大吉诺因生物科技有限公司 | 多肽及其应用 |
| CN109952308B (zh) * | 2016-11-29 | 2022-09-23 | 武汉华大吉诺因生物科技有限公司 | 多肽及其应用 |
| KR102127449B1 (ko) * | 2017-02-08 | 2020-06-26 | 사회복지법인 삼성생명공익재단 | 생존율 예측 모델 생성 방법, 장치 및 컴퓨터 프로그램 |
| CN108504732A (zh) * | 2017-02-27 | 2018-09-07 | 复旦大学附属华山医院 | 一种建立胃癌的风险预测模型的方法 |
| KR101940657B1 (ko) * | 2017-04-24 | 2019-01-21 | (주) 노보믹스 | 위암의 생물학적 특성에 기반한 군 구분 및 예후 예측 시스템 |
| CN107090503B (zh) * | 2017-04-27 | 2020-06-19 | 元码基因科技（北京）股份有限公司 | 探针组合物、基因捕获芯片、试剂盒及其应用 |
| CN107641653B (zh) * | 2017-10-20 | 2021-02-19 | 南方医科大学南方医院 | Macc1-as1探针在制备用于预测胃癌临床预后的诊断试剂中的应用 |
| CN113851185B (zh) * | 2021-11-29 | 2022-04-19 | 求臻医学科技（北京）有限公司 | 一种用于非小细胞肺癌患者免疫治疗的预后评估方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2537633T3 (es) * | 2004-03-02 | 2015-06-10 | The Johns Hopkins University | Mutaciones del gen de PIK3CA en cánceres humanos |
| WO2007081720A2 (en) * | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
| CA2648021A1 (en) * | 2006-03-31 | 2007-10-11 | Ordway Research Institute, Inc. | Prognostic and diagnostic method for cancer therapy |
| NZ576852A (en) * | 2006-10-26 | 2012-02-24 | Genentech Inc | Genetic variations (in the phosphatidylinositol 3-kinase regulatory subunit 1 pik3r1 protein) associated with tumors and method of testing for |
| CA2724348A1 (en) * | 2008-05-15 | 2009-11-19 | University Of Southern California | Genotype and expression analysis for use in predicting outcome and therapy selection |
| KR20120061010A (ko) * | 2010-11-02 | 2012-06-12 | 서울대학교산학협력단 | 위암 진단 방법 |
| CN103459597B (zh) * | 2010-12-13 | 2016-03-30 | 社会福祉法人三星生命公益财团 | 用于预测胃癌预后的标记和使用该标记预测胃癌预后的方法 |
| SG2014010276A (en) * | 2011-08-18 | 2014-03-28 | Nestec Sa | Compositions and methods for detecting allelic variants |
-
2013
- 2013-04-05 KR KR1020130037336A patent/KR101501826B1/ko not_active Expired - Fee Related
-
2014
- 2014-04-07 WO PCT/KR2014/002959 patent/WO2014163445A1/ko not_active Ceased
- 2014-04-07 JP JP2016506253A patent/JP6356217B2/ja not_active Expired - Fee Related
- 2014-04-07 US US14/782,519 patent/US20160040253A1/en not_active Abandoned
- 2014-04-07 EP EP14779750.0A patent/EP2982986B1/en active Active
- 2014-04-07 CN CN201480024783.5A patent/CN105431738B/zh active Active
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