KR101501826B1 - 위암에 대한 예후 예측 모형의 제조방법 - Google Patents

위암에 대한 예후 예측 모형의 제조방법 Download PDF

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KR101501826B1
KR101501826B1 KR1020130037336A KR20130037336A KR101501826B1 KR 101501826 B1 KR101501826 B1 KR 101501826B1 KR 1020130037336 A KR1020130037336 A KR 1020130037336A KR 20130037336 A KR20130037336 A KR 20130037336A KR 101501826 B1 KR101501826 B1 KR 101501826B1
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group
expression
prognosis
gastric cancer
amino acid
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Korean (ko)
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KR20140121524A (ko
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허용민
노성훈
서진석
정재호
박은성
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연세대학교 산학협력단
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Priority to KR1020130037336A priority Critical patent/KR101501826B1/ko
Priority to PCT/KR2014/002959 priority patent/WO2014163445A1/ko
Priority to CN201480024783.5A priority patent/CN105431738B/zh
Priority to US14/782,519 priority patent/US20160040253A1/en
Priority to JP2016506253A priority patent/JP6356217B2/ja
Priority to EP14779750.0A priority patent/EP2982986B1/en
Publication of KR20140121524A publication Critical patent/KR20140121524A/ko
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
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    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • C12Q2600/00—Oligonucleotides characterized by their use
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KR1020130037336A 2013-04-05 2013-04-05 위암에 대한 예후 예측 모형의 제조방법 Expired - Fee Related KR101501826B1 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
KR1020130037336A KR101501826B1 (ko) 2013-04-05 2013-04-05 위암에 대한 예후 예측 모형의 제조방법
PCT/KR2014/002959 WO2014163445A1 (ko) 2013-04-05 2014-04-07 위암에 대한 예후 예측 모형의 제조방법
CN201480024783.5A CN105431738B (zh) 2013-04-05 2014-04-07 胃癌的预后预测模型的建立方法
US14/782,519 US20160040253A1 (en) 2013-04-05 2014-04-07 Method for manufacturing gastric cancer prognosis prediction model
JP2016506253A JP6356217B2 (ja) 2013-04-05 2014-04-07 胃癌に対する予後予測模型の製造方法
EP14779750.0A EP2982986B1 (en) 2013-04-05 2014-04-07 Method for manufacturing gastric cancer prognosis prediction model

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020130037336A KR101501826B1 (ko) 2013-04-05 2013-04-05 위암에 대한 예후 예측 모형의 제조방법

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KR20140121524A KR20140121524A (ko) 2014-10-16
KR101501826B1 true KR101501826B1 (ko) 2015-03-13

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US (1) US20160040253A1 (enExample)
EP (1) EP2982986B1 (enExample)
JP (1) JP6356217B2 (enExample)
KR (1) KR101501826B1 (enExample)
CN (1) CN105431738B (enExample)
WO (1) WO2014163445A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018147653A1 (ko) * 2017-02-08 2018-08-16 사회복지법인 삼성생명공익재단 생존율 예측 모델 생성 방법, 장치 및 컴퓨터 프로그램

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018094569A1 (zh) * 2016-11-22 2018-05-31 深圳华大基因研究院 多肽及其应用
CN109952308B (zh) * 2016-11-29 2022-09-23 武汉华大吉诺因生物科技有限公司 多肽及其应用
CN108504732A (zh) * 2017-02-27 2018-09-07 复旦大学附属华山医院 一种建立胃癌的风险预测模型的方法
KR101940657B1 (ko) * 2017-04-24 2019-01-21 (주) 노보믹스 위암의 생물학적 특성에 기반한 군 구분 및 예후 예측 시스템
CN107090503B (zh) * 2017-04-27 2020-06-19 元码基因科技（北京）股份有限公司 探针组合物、基因捕获芯片、试剂盒及其应用
CN107641653B (zh) * 2017-10-20 2021-02-19 南方医科大学南方医院 Macc1-as1探针在制备用于预测胃癌临床预后的诊断试剂中的应用
CN113851185B (zh) * 2021-11-29 2022-04-19 求臻医学科技（北京）有限公司 一种用于非小细胞肺癌患者免疫治疗的预后评估方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100055095A1 (en) * 2006-10-26 2010-03-04 Zhengyan Kan Genetic variations associated with tumors
KR20120061010A (ko) * 2010-11-02 2012-06-12 서울대학교산학협력단 위암 진단 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2437590T3 (es) * 2004-03-02 2014-01-13 The Johns-Hopkins University Mutaciones del gen de PIK3CA en cánceres humanos
ES2553442T3 (es) * 2006-01-05 2015-12-09 The Ohio State University Research Foundation Procedimientos basados en los microARN para el diagnóstico, pronóstico y tratamiento del cáncer de pulmón
CA2648021A1 (en) * 2006-03-31 2007-10-11 Ordway Research Institute, Inc. Prognostic and diagnostic method for cancer therapy
EP2288728A4 (en) * 2008-05-15 2011-11-02 Univ Southern California GENOTYP AND EXPRESSION ANALYSIS FOR USE IN PROGNOSIS AND THERAPY SELECTION
WO2012081898A2 (ko) * 2010-12-13 2012-06-21 사회복지법인 삼성생명공익재단 위암의 예후 예측용 마커 및 이를 이용하는 위암의 예후 예측 방법
AU2012296385A1 (en) * 2011-08-18 2014-02-20 Nestec S.A. Compositions and methods for detecting allelic variants

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100055095A1 (en) * 2006-10-26 2010-03-04 Zhengyan Kan Genetic variations associated with tumors
KR20120061010A (ko) * 2010-11-02 2012-06-12 서울대학교산학협력단 위암 진단 방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BJC,108권,1495-1501면(온라인공개: 2013.03.19.) *
BJC,108권,1495-1501면(온라인공개: 2013.03.19.)*

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018147653A1 (ko) * 2017-02-08 2018-08-16 사회복지법인 삼성생명공익재단 생존율 예측 모델 생성 방법, 장치 및 컴퓨터 프로그램

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CN105431738B (zh) 2017-11-03
CN105431738A (zh) 2016-03-23
KR20140121524A (ko) 2014-10-16
JP2016515390A (ja) 2016-05-30
EP2982986A4 (en) 2016-12-07
US20160040253A1 (en) 2016-02-11
JP6356217B2 (ja) 2018-07-11
EP2982986B1 (en) 2019-01-30
WO2014163445A1 (ko) 2014-10-09
EP2982986A1 (en) 2016-02-10

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