JP6356217B2 - 胃癌に対する予後予測模型の製造方法 - Google Patents
胃癌に対する予後予測模型の製造方法 Download PDFInfo
- Publication number
- JP6356217B2 JP6356217B2 JP2016506253A JP2016506253A JP6356217B2 JP 6356217 B2 JP6356217 B2 JP 6356217B2 JP 2016506253 A JP2016506253 A JP 2016506253A JP 2016506253 A JP2016506253 A JP 2016506253A JP 6356217 B2 JP6356217 B2 JP 6356217B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- gene
- gastric cancer
- expression
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Data Mining & Analysis (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Databases & Information Systems (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Software Systems (AREA)
- Artificial Intelligence (AREA)
- Evolutionary Computation (AREA)
- Bioethics (AREA)
- Computer Vision & Pattern Recognition (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2013-0037336 | 2013-04-05 | ||
| KR1020130037336A KR101501826B1 (ko) | 2013-04-05 | 2013-04-05 | 위암에 대한 예후 예측 모형의 제조방법 |
| PCT/KR2014/002959 WO2014163445A1 (ko) | 2013-04-05 | 2014-04-07 | 위암에 대한 예후 예측 모형의 제조방법 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016515390A JP2016515390A (ja) | 2016-05-30 |
| JP2016515390A5 JP2016515390A5 (enExample) | 2017-03-23 |
| JP6356217B2 true JP6356217B2 (ja) | 2018-07-11 |
Family
ID=51658661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506253A Expired - Fee Related JP6356217B2 (ja) | 2013-04-05 | 2014-04-07 | 胃癌に対する予後予測模型の製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160040253A1 (enExample) |
| EP (1) | EP2982986B1 (enExample) |
| JP (1) | JP6356217B2 (enExample) |
| KR (1) | KR101501826B1 (enExample) |
| CN (1) | CN105431738B (enExample) |
| WO (1) | WO2014163445A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109923121B (zh) * | 2016-11-22 | 2022-12-23 | 武汉华大吉诺因生物科技有限公司 | 多肽及其应用 |
| CN109952308B (zh) * | 2016-11-29 | 2022-09-23 | 武汉华大吉诺因生物科技有限公司 | 多肽及其应用 |
| KR102127449B1 (ko) * | 2017-02-08 | 2020-06-26 | 사회복지법인 삼성생명공익재단 | 생존율 예측 모델 생성 방법, 장치 및 컴퓨터 프로그램 |
| CN108504732A (zh) * | 2017-02-27 | 2018-09-07 | 复旦大学附属华山医院 | 一种建立胃癌的风险预测模型的方法 |
| KR101940657B1 (ko) * | 2017-04-24 | 2019-01-21 | (주) 노보믹스 | 위암의 생물학적 특성에 기반한 군 구분 및 예후 예측 시스템 |
| CN107090503B (zh) * | 2017-04-27 | 2020-06-19 | 元码基因科技(北京)股份有限公司 | 探针组合物、基因捕获芯片、试剂盒及其应用 |
| CN107641653B (zh) * | 2017-10-20 | 2021-02-19 | 南方医科大学南方医院 | Macc1-as1探针在制备用于预测胃癌临床预后的诊断试剂中的应用 |
| CN113851185B (zh) * | 2021-11-29 | 2022-04-19 | 求臻医学科技(北京)有限公司 | 一种用于非小细胞肺癌患者免疫治疗的预后评估方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2537633T3 (es) * | 2004-03-02 | 2015-06-10 | The Johns Hopkins University | Mutaciones del gen de PIK3CA en cánceres humanos |
| WO2007081720A2 (en) * | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
| CA2648021A1 (en) * | 2006-03-31 | 2007-10-11 | Ordway Research Institute, Inc. | Prognostic and diagnostic method for cancer therapy |
| NZ576852A (en) * | 2006-10-26 | 2012-02-24 | Genentech Inc | Genetic variations (in the phosphatidylinositol 3-kinase regulatory subunit 1 pik3r1 protein) associated with tumors and method of testing for |
| CA2724348A1 (en) * | 2008-05-15 | 2009-11-19 | University Of Southern California | Genotype and expression analysis for use in predicting outcome and therapy selection |
| KR20120061010A (ko) * | 2010-11-02 | 2012-06-12 | 서울대학교산학협력단 | 위암 진단 방법 |
| CN103459597B (zh) * | 2010-12-13 | 2016-03-30 | 社会福祉法人三星生命公益财团 | 用于预测胃癌预后的标记和使用该标记预测胃癌预后的方法 |
| SG2014010276A (en) * | 2011-08-18 | 2014-03-28 | Nestec Sa | Compositions and methods for detecting allelic variants |
-
2013
- 2013-04-05 KR KR1020130037336A patent/KR101501826B1/ko not_active Expired - Fee Related
-
2014
- 2014-04-07 WO PCT/KR2014/002959 patent/WO2014163445A1/ko not_active Ceased
- 2014-04-07 JP JP2016506253A patent/JP6356217B2/ja not_active Expired - Fee Related
- 2014-04-07 US US14/782,519 patent/US20160040253A1/en not_active Abandoned
- 2014-04-07 EP EP14779750.0A patent/EP2982986B1/en active Active
- 2014-04-07 CN CN201480024783.5A patent/CN105431738B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2982986A4 (en) | 2016-12-07 |
| KR101501826B1 (ko) | 2015-03-13 |
| EP2982986A1 (en) | 2016-02-10 |
| EP2982986B1 (en) | 2019-01-30 |
| WO2014163445A1 (ko) | 2014-10-09 |
| US20160040253A1 (en) | 2016-02-11 |
| CN105431738B (zh) | 2017-11-03 |
| CN105431738A (zh) | 2016-03-23 |
| JP2016515390A (ja) | 2016-05-30 |
| KR20140121524A (ko) | 2014-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6356217B2 (ja) | 胃癌に対する予後予測模型の製造方法 | |
| CA2776751C (en) | Methods to predict clinical outcome of cancer | |
| CA2852098C (en) | Colorectal cancer associated circulating nucleic acid biomarkers | |
| JP2020031642A (ja) | 遺伝子発現を用いた前立腺癌の予後を定量化する方法 | |
| JP2014509189A (ja) | 結腸ガン遺伝子発現シグネチャーおよび使用方法 | |
| KR20080065476A (ko) | 폐암 환자 또는 폐암 치료를 받은 폐암 환자에 대한 폐암재발의 위험을 예측하는 방법, 폐암 환자 또는 폐암 치료를받은 환자의 폐암 재발 위험성에 대한 보고서를 작성하는방법, 그에 의하여 작성된 보고서, 폐암 환자 또는 폐암치료를 받은 폐암 환자의 폐암 재발 위험을 진단하기 위한조성물, 키트 및 마이크로어레이 | |
| CN104903468A (zh) | 用于帕金森氏病的新诊断MiRNA标志物 | |
| WO2017223216A1 (en) | Compositions and methods for diagnosing lung cancers using gene expression profiles | |
| US9890430B2 (en) | Copy number aberration driven endocrine response gene signature | |
| EP3638787A1 (en) | Diagnostic, prognostic and therapeutic uses of long noncoding rnas for pathologies and toxicities inducing heart disorders | |
| JP2014503221A (ja) | 結腸直腸がんの再発予測のためのバイオマーカー | |
| WO2017112738A1 (en) | Methods for measuring microsatellite instability | |
| CN116157539A (zh) | 循环肿瘤核酸分子的多模态分析 | |
| CA2696947A1 (en) | Methods and tools for prognosis of cancer in er- patients | |
| CN104428426B (zh) | 多发性硬化的诊断miRNA概况 | |
| JP2012513752A (ja) | 結腸直腸癌細胞を含む試料を型判別するための方法および手段 | |
| WO2023152568A2 (en) | Compositions and methods for characterizing lung cancer | |
| JP6066116B2 (ja) | 個体が大腸癌に罹患する可能性をinvitroで決定するための方法及びキット | |
| JP2021503921A (ja) | 癌を性質決定する組成物および方法 | |
| EP1683862B1 (en) | Microarray for assessing neuroblastoma prognosis and method of assessing neuroblastoma prognosis | |
| CN108103064B (zh) | 长链非编码rna及其应用 | |
| KR101504818B1 (ko) | 위암에 대한 예후 예측 시스템 | |
| US20160312289A1 (en) | Biomolecular events in cancer revealed by attractor molecular signatures | |
| CN114634982A (zh) | 一种检测多核苷酸变异的方法 | |
| CN107974486A (zh) | 一种乳腺癌术后复发风险检测方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20151203 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20160916 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20161216 |
|
| A524 | Written submission of copy of amendment under article 19 pct |
Free format text: JAPANESE INTERMEDIATE CODE: A524 Effective date: 20170213 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20170627 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170724 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20171024 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20171225 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20180521 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20180613 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6356217 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| LAPS | Cancellation because of no payment of annual fees |