JP2012527245A5 - - Google Patents
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- Publication number
- JP2012527245A5 JP2012527245A5 JP2012512038A JP2012512038A JP2012527245A5 JP 2012527245 A5 JP2012527245 A5 JP 2012527245A5 JP 2012512038 A JP2012512038 A JP 2012512038A JP 2012512038 A JP2012512038 A JP 2012512038A JP 2012527245 A5 JP2012527245 A5 JP 2012527245A5
- Authority
- JP
- Japan
- Prior art keywords
- carpi
- genes
- cells
- cell
- cardiogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 18
- 108090000623 proteins and genes Proteins 0.000 claims 15
- 210000004027 cell Anatomy 0.000 claims 12
- 241000124008 Mammalia Species 0.000 claims 7
- 230000001269 cardiogenic effect Effects 0.000 claims 7
- 101000819074 Homo sapiens Transcription factor GATA-4 Proteins 0.000 claims 3
- 101000819088 Homo sapiens Transcription factor GATA-6 Proteins 0.000 claims 3
- 101000931374 Homo sapiens Zinc finger protein ZFPM1 Proteins 0.000 claims 3
- 101000931371 Homo sapiens Zinc finger protein ZFPM2 Proteins 0.000 claims 3
- 101150088608 Kdr gene Proteins 0.000 claims 3
- 102000055120 MEF2 Transcription Factors Human genes 0.000 claims 3
- 108010018650 MEF2 Transcription Factors Proteins 0.000 claims 3
- -1 Mesp1 Proteins 0.000 claims 3
- 101150114527 Nkx2-5 gene Proteins 0.000 claims 3
- 102100021380 Transcription factor GATA-4 Human genes 0.000 claims 3
- 102100021382 Transcription factor GATA-6 Human genes 0.000 claims 3
- 102000016549 Vascular Endothelial Growth Factor Receptor-2 Human genes 0.000 claims 3
- 101100460507 Xenopus laevis nkx-2.5 gene Proteins 0.000 claims 3
- 102100020993 Zinc finger protein ZFPM1 Human genes 0.000 claims 3
- 102100020996 Zinc finger protein ZFPM2 Human genes 0.000 claims 3
- 108020004999 messenger RNA Proteins 0.000 claims 3
- 101150115978 tbx5 gene Proteins 0.000 claims 3
- 230000000747 cardiac effect Effects 0.000 claims 2
- 210000004962 mammalian cell Anatomy 0.000 claims 2
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 1
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 1
- 108700011259 MicroRNAs Proteins 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 210000002308 embryonic cell Anatomy 0.000 claims 1
- 210000004700 fetal blood Anatomy 0.000 claims 1
- 230000006870 function Effects 0.000 claims 1
- 210000004602 germ cell Anatomy 0.000 claims 1
- 230000004217 heart function Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 210000001082 somatic cell Anatomy 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| USPCT/US2009/044751 | 2009-05-20 | ||
| USPCT/US2009/044751 | 2009-05-20 | ||
| PCT/US2010/035616 WO2010135555A1 (en) | 2009-05-20 | 2010-05-20 | Method for determining the cardio-generative potential of mammalian cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012527245A JP2012527245A (ja) | 2012-11-08 |
| JP2012527245A5 true JP2012527245A5 (enExample) | 2013-07-04 |
| JP5921430B2 JP5921430B2 (ja) | 2016-05-24 |
Family
ID=42316056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012512038A Active JP5921430B2 (ja) | 2009-05-20 | 2010-05-20 | 哺乳類細胞の心臓発生能を決定する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20160298086A1 (enExample) |
| EP (2) | EP2433125B1 (enExample) |
| JP (1) | JP5921430B2 (enExample) |
| KR (1) | KR101808349B1 (enExample) |
| CN (1) | CN102498399A (enExample) |
| AU (1) | AU2010249821B2 (enExample) |
| BR (1) | BRPI1010684A2 (enExample) |
| CA (1) | CA2761807C (enExample) |
| IL (1) | IL216368A (enExample) |
| NZ (1) | NZ595919A (enExample) |
| RU (1) | RU2624498C2 (enExample) |
| TW (1) | TWI564558B (enExample) |
| WO (1) | WO2010135555A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8173118B2 (en) | 2004-07-30 | 2012-05-08 | Mayo Foundation For Medical Education And Research | Compositions consisting essentially of TGF-β, BMP-2 FGF-4, leukemia inhibitory factor, IGF-1, IL-6 and H-α-thrombin |
| US9765298B2 (en) | 2006-07-24 | 2017-09-19 | Mayo Foundation For Medical Education And Research | Methods and materials for providing cardiac cells |
| WO2009145761A1 (en) | 2008-05-27 | 2009-12-03 | Mayo Foundation For Medical Education And Research | Methods and materials for using cells to treat heart tissue |
| LT2494039T (lt) * | 2009-10-31 | 2019-07-25 | Genesis Technologies Limited | Ląstelių perprogramavimo būdai ir jų panaudojimas |
| US20140038291A1 (en) | 2009-10-31 | 2014-02-06 | New World Laboratories Inc. | Methods for reprogramming cells and uses thereof |
| US9453205B2 (en) * | 2009-10-31 | 2016-09-27 | Genesis Technologies Limited | Methods for reprogramming cells and uses thereof |
| US9185690B2 (en) * | 2012-02-29 | 2015-11-10 | Sharp Kabushiki Kaisha | Allocating and determining resources for a device-to-device link |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020061837A1 (en) | 1996-09-05 | 2002-05-23 | Lough John W. | Bone morphogenetic protein and fibroblast growth factor compositions and methods for the induction of cardiogenesis |
| US6324479B1 (en) * | 1998-05-08 | 2001-11-27 | Rosetta Impharmatics, Inc. | Methods of determining protein activity levels using gene expression profiles |
| US6218122B1 (en) * | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
| US7547674B2 (en) * | 2001-06-06 | 2009-06-16 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| TWI226440B (en) * | 2000-09-08 | 2005-01-11 | Kuo Kwang Biotech Corp | Predicting survival of patients with squamous cell carcinoma |
| EP1412479A4 (en) | 2001-07-12 | 2004-07-28 | Geron Corp | CELLS WITH CARDIOMYOCYTE GENERATION PRODUCED FROM HUMAN PLURIPOTENT STEM CELLS |
| US20050244384A1 (en) * | 2002-04-01 | 2005-11-03 | Law Peter K | Cellular transplantation for heart regeneration |
| US20050043260A1 (en) * | 2003-04-21 | 2005-02-24 | Baylor College Of Medicine | Wnt as a factor for cardiac myogenesis |
| BRPI0414961A (pt) * | 2003-10-03 | 2006-11-07 | Keiichi Fukuda | processo de indução da diferenciação de células tronco em células do miocárdio |
| DE10347436B4 (de) * | 2003-10-13 | 2007-08-02 | Johann Wolfgang Goethe-Universität Frankfurt am Main | In vitro Verfahren zur Diagnose der kardiovaskulären Funktionalität von Blut-abgeleiteter zirkulierender Vorläuferzellen (BDP) |
| US20070077578A1 (en) * | 2004-03-02 | 2007-04-05 | Primagen Holding B.V. | Diagnosis of (a risk of ) disease and monitoring of therapy |
| US20050277124A1 (en) * | 2004-06-10 | 2005-12-15 | White Steven M | Cardiac conduction system cells and uses thereof |
| JP2009531021A (ja) * | 2006-02-16 | 2009-09-03 | フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール | 骨格筋周囲血管芽細胞および心筋中胚葉性血管芽細胞、それらの単離および使用方法 |
| US9765298B2 (en) | 2006-07-24 | 2017-09-19 | Mayo Foundation For Medical Education And Research | Methods and materials for providing cardiac cells |
| US20100166714A1 (en) * | 2006-11-02 | 2010-07-01 | The General Hospital Corporation | Cardiovascular stem cells, methods for stem cell isolation, and uses thereof |
| CN101573442A (zh) * | 2006-11-09 | 2009-11-04 | J·大卫格莱斯顿学会 | 诱导心肌细胞形成的方法 |
| WO2009089476A1 (en) * | 2008-01-11 | 2009-07-16 | Kardia Therapeutics, Inc. | Adult human cardiac-derived progenitor cells |
| EP2100954A1 (en) * | 2008-03-10 | 2009-09-16 | Assistance Publique - Hopitaux de Paris | Method for generating primate cardiac progenitor cells for clinical use from primate embryonic stem cells, and their applications |
| WO2009145761A1 (en) * | 2008-05-27 | 2009-12-03 | Mayo Foundation For Medical Education And Research | Methods and materials for using cells to treat heart tissue |
-
2010
- 2010-05-20 AU AU2010249821A patent/AU2010249821B2/en not_active Ceased
- 2010-05-20 EP EP10721224.3A patent/EP2433125B1/en active Active
- 2010-05-20 BR BRPI1010684A patent/BRPI1010684A2/pt not_active IP Right Cessation
- 2010-05-20 CN CN2010800215516A patent/CN102498399A/zh active Pending
- 2010-05-20 JP JP2012512038A patent/JP5921430B2/ja active Active
- 2010-05-20 CA CA2761807A patent/CA2761807C/en not_active Expired - Fee Related
- 2010-05-20 KR KR1020117027716A patent/KR101808349B1/ko not_active Expired - Fee Related
- 2010-05-20 EP EP18208719.7A patent/EP3524980A1/en not_active Withdrawn
- 2010-05-20 WO PCT/US2010/035616 patent/WO2010135555A1/en not_active Ceased
- 2010-05-20 RU RU2011143063A patent/RU2624498C2/ru not_active IP Right Cessation
- 2010-05-20 NZ NZ595919A patent/NZ595919A/en not_active IP Right Cessation
- 2010-05-20 TW TW099116051A patent/TWI564558B/zh not_active IP Right Cessation
-
2011
- 2011-11-14 IL IL216368A patent/IL216368A/en not_active IP Right Cessation
-
2016
- 2016-06-21 US US15/188,582 patent/US20160298086A1/en not_active Abandoned
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