CA2761807C - Method for determining the cardio-generative potential of mammalian cells - Google Patents

Method for determining the cardio-generative potential of mammalian cells Download PDF

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Publication number
CA2761807C
CA2761807C CA2761807A CA2761807A CA2761807C CA 2761807 C CA2761807 C CA 2761807C CA 2761807 A CA2761807 A CA 2761807A CA 2761807 A CA2761807 A CA 2761807A CA 2761807 C CA2761807 C CA 2761807C
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Prior art keywords
cells
carpi
genes
potential
expression
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Expired - Fee Related
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CA2761807A
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English (en)
French (fr)
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CA2761807A1 (en
Inventor
Andre Terzic
Atta Behfar
Roland Gordon-Beresford
Vinciane Gaussin
Christian Homsy
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Celyad Oncology SA
Mayo Clinic in Florida
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Celyad SA
Mayo Clinic in Florida
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/73—Hydrolases (EC 3.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1346—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from mesenchymal stem cells
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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  • Cardiology (AREA)
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CA2761807A 2009-05-20 2010-05-20 Method for determining the cardio-generative potential of mammalian cells Expired - Fee Related CA2761807C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
USPCT/US2009/044751 2009-05-20
USPCT/US2009/044751 2009-05-20
PCT/US2010/035616 WO2010135555A1 (en) 2009-05-20 2010-05-20 Method for determining the cardio-generative potential of mammalian cells

Publications (2)

Publication Number Publication Date
CA2761807A1 CA2761807A1 (en) 2010-11-25
CA2761807C true CA2761807C (en) 2018-01-09

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CA2761807A Expired - Fee Related CA2761807C (en) 2009-05-20 2010-05-20 Method for determining the cardio-generative potential of mammalian cells

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US (1) US20160298086A1 (enExample)
EP (2) EP2433125B1 (enExample)
JP (1) JP5921430B2 (enExample)
KR (1) KR101808349B1 (enExample)
CN (1) CN102498399A (enExample)
AU (1) AU2010249821B2 (enExample)
BR (1) BRPI1010684A2 (enExample)
CA (1) CA2761807C (enExample)
IL (1) IL216368A (enExample)
NZ (1) NZ595919A (enExample)
RU (1) RU2624498C2 (enExample)
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WO (1) WO2010135555A1 (enExample)

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WO2009145761A1 (en) 2008-05-27 2009-12-03 Mayo Foundation For Medical Education And Research Methods and materials for using cells to treat heart tissue
LT2494039T (lt) * 2009-10-31 2019-07-25 Genesis Technologies Limited Ląstelių perprogramavimo būdai ir jų panaudojimas
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US9453205B2 (en) * 2009-10-31 2016-09-27 Genesis Technologies Limited Methods for reprogramming cells and uses thereof
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EP2433125B1 (en) 2018-11-28
KR20120034624A (ko) 2012-04-12
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