|
CA2427890A1
(en)
|
1992-02-05 |
1993-08-19 |
Ralf Anderskewitz |
New amidine derivatives, the preparation and use thereof
|
|
US5656642A
(en)
|
1993-04-07 |
1997-08-12 |
Otsuka Pharmaceutical Co., Ltd. |
Peripheral vasodilating agent containing piperidine derivative as active ingredient
|
|
US5716993A
(en)
|
1993-12-27 |
1998-02-10 |
Eisai Co., Ltd. |
Anthranilic acid derivatives
|
|
GB9500580D0
(en)
|
1995-01-12 |
1995-03-01 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5763618A
(en)
|
1995-05-12 |
1998-06-09 |
Konica Corporation |
Manufacturing method of sulfides
|
|
DE19545878A1
(de)
|
1995-12-08 |
1997-06-12 |
Basf Ag |
Pyridylcarbamate, Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung
|
|
PT892780E
(pt)
|
1996-02-22 |
2003-02-28 |
Bristol Myers Squibb Pharma Co |
Analogos de m-amidino fenilo como inibidores do factor xa
|
|
AU721952B2
(en)
|
1996-04-03 |
2000-07-20 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
|
AU730224B2
(en)
|
1996-12-23 |
2001-03-01 |
Du Pont Pharmaceuticals Company |
Nitrogen containing heteroaromatics as factor Xa inhibitors
|
|
US6020357A
(en)
|
1996-12-23 |
2000-02-01 |
Dupont Pharmaceuticals Company |
Nitrogen containing heteroaromatics as factor Xa inhibitors
|
|
US6187797B1
(en)
|
1996-12-23 |
2001-02-13 |
Dupont Pharmaceuticals Company |
Phenyl-isoxazoles as factor XA Inhibitors
|
|
DE69720773T2
(de)
|
1996-12-23 |
2004-01-29 |
Bristol Myers Squibb Pharma Co |
SAUERSTOFF ODER SCHWEFEL ENTHALTENDE 5-GLIEDRIGE HETEROAROMATISHE DERIVATIVE ALS FACTOR Xa HEMMER
|
|
SK174699A3
(en)
|
1997-06-19 |
2000-08-14 |
Du Pont Pharm Co |
Inhibitors of factor xa with a neutral p1 specificity group
|
|
US6339099B1
(en)
|
1997-06-20 |
2002-01-15 |
Dupont Pharmaceuticals Company |
Guanidine mimics as factor Xa inhibitors
|
|
BR9811585A
(pt)
|
1997-07-30 |
2000-09-26 |
American Home Prod |
Agonistas de vasopressinas tricìclicas
|
|
AU8592598A
(en)
|
1997-07-30 |
1999-02-22 |
Wyeth |
Tricyclic vasopressin agonists
|
|
US6511974B1
(en)
|
1997-07-30 |
2003-01-28 |
Wyeth |
Tricyclic vasopressin agonists
|
|
WO1999055663A1
(en)
|
1998-04-29 |
1999-11-04 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of impdh enzyme
|
|
US6121271A
(en)
|
1998-05-12 |
2000-09-19 |
American Home Products Corporation |
Naphtho[2,3-B]heteroar-4-yl derivatives
|
|
AU3791699A
(en)
|
1998-05-12 |
1999-11-29 |
American Home Products Corporation |
Naphtho{2,3-b}heteroar-4-yl derivatives
|
|
JP2000109465A
(ja)
|
1998-08-05 |
2000-04-18 |
Nippon Soda Co Ltd |
フェニルピラゾ―ル化合物、製法及び抗高脂血症薬
|
|
CA2348267A1
(en)
|
1998-10-29 |
2000-05-11 |
Henry H. Gu |
Novel inhibitors of impdh enzyme
|
|
WO2000029399A1
(en)
|
1998-11-12 |
2000-05-25 |
Boehringer Ingelheim (Canada) Ltd. |
Antiherpes compounds
|
|
DE60001054T2
(de)
|
1999-02-04 |
2003-07-24 |
Wyeth, Madison |
Trizyclische pyridin n-oxide vasopressin agonisten
|
|
JP2000256358A
(ja)
|
1999-03-10 |
2000-09-19 |
Yamanouchi Pharmaceut Co Ltd |
ピラゾール誘導体
|
|
YU72201A
(sh)
|
1999-04-28 |
2005-07-19 |
Aventis Pharma Deutschland Gmbh. |
Derivati di-aril kiseline kao ppar receptorski ligandi
|
|
JP2003510280A
(ja)
|
1999-09-27 |
2003-03-18 |
アメリカン・サイアナミド・カンパニー |
バソプレッシンアゴニスト処方および製法
|
|
CA2397575A1
(en)
|
2000-01-13 |
2001-07-19 |
Tularik Inc. |
Antibacterial agents
|
|
WO2001068605A1
(en)
|
2000-03-13 |
2001-09-20 |
Pharmacia Corporation |
Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade
|
|
MY138097A
(en)
|
2000-03-22 |
2009-04-30 |
Du Pont |
Insecticidal anthranilamides
|
|
AU2001273040A1
(en)
|
2000-06-27 |
2002-01-08 |
Du Pont Pharmaceuticals Company |
Factor xa inhibitors
|
|
DE10063008A1
(de)
|
2000-12-16 |
2002-06-20 |
Merck Patent Gmbh |
Carbonsäureamidderivate
|
|
AU2002248432A1
(en)
|
2001-02-14 |
2002-08-28 |
Sankyo Company, Limited |
Oxazole derivatives, their preparation and their use as cytokine inhibitors
|
|
ES2364550T3
(es)
|
2001-03-05 |
2011-09-06 |
E. I. Du Pont De Nemours And Company |
Agentes de control de plagas de invertebrados de diamidas heterocíclicas.
|
|
DE10110749A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Substituierte Aminodicarbonsäurederivate
|
|
DE10111842A1
(de)
|
2001-03-13 |
2002-09-19 |
Boehringer Ingelheim Pharma |
Antithrombotische Carbonsäureamide, deren Herstellung und deren Verwendung als Arzneimittel
|
|
WO2002076959A1
(en)
|
2001-03-23 |
2002-10-03 |
Takeda Chemical Industries, Ltd. |
Five-membered heterocyclic alkanoic acid derivative
|
|
CA2447475A1
(en)
|
2001-05-25 |
2002-12-05 |
Chu-Biao Xue |
Hydantion derivatives as inhibitors of matrix metalloproteinases
|
|
DE10130374A1
(de)
|
2001-06-23 |
2003-01-02 |
Boehringer Ingelheim Pharma |
Substituierte N-Acyl-anilinderivate, deren Herstellung und deren Verwendung als Arzneimittel
|
|
CZ20033437A3
(cs)
|
2001-06-28 |
2004-09-15 |
Smithkline Beecham P.L.C. |
N-Aroylové cyklické aminové deriváty jako antagonisté orexinového receptoru
|
|
GB0115862D0
(en)
|
2001-06-28 |
2001-08-22 |
Smithkline Beecham Plc |
Compounds
|
|
WO2003004474A1
(en)
|
2001-07-06 |
2003-01-16 |
Syngenta Participations Ag |
Pesticidally active aminoacetonitriles
|
|
EP1423380B1
(en)
|
2001-08-03 |
2010-12-15 |
Vertex Pharmaceuticals Incorporated |
Pyrazole-derived kinase inhibitors and uses thereof
|
|
GB0124463D0
(en)
|
2001-10-11 |
2001-12-05 |
Smithkline Beecham Plc |
Compounds
|
|
SE0103644D0
(sv)
|
2001-11-01 |
2001-11-01 |
Astrazeneca Ab |
Therapeutic isoquinoline compounds
|
|
US6984735B2
(en)
|
2001-12-03 |
2006-01-10 |
Wyeth |
Process for making an aldehyde
|
|
US7101883B2
(en)
|
2002-03-18 |
2006-09-05 |
Bristol-Myers Squibb Company |
Uracil derivatives as inhibitors of TNF-α converting enzyme (TACE) and matrix metalloproteinases
|
|
EP1487796A4
(en)
|
2002-03-28 |
2005-11-16 |
Neurogen Corp |
SUBSTITUTED BIARYLAMIDES AS MODULATORS OF THE C5A RECEPTOR
|
|
US6846838B2
(en)
|
2002-06-19 |
2005-01-25 |
Bristol-Myers Squibb Company |
Ureido-substituted aniline compounds useful as serine protease inhibitors
|
|
US20040044041A1
(en)
|
2002-08-06 |
2004-03-04 |
Kuduk Scott D. |
2-(Biarylalkyl)amino-3-(cyanoalkanoylamino)pyridine derivatives
|
|
AU2003265395A1
(en)
|
2002-08-14 |
2004-03-03 |
Ppd Discovery, Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
|
US7041693B2
(en)
|
2002-10-04 |
2006-05-09 |
Bristol-Myers Squibb Company |
Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
|
|
US20040082641A1
(en)
|
2002-10-28 |
2004-04-29 |
Rytved Klaus Asger |
Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases
|
|
WO2004043926A1
(en)
|
2002-11-11 |
2004-05-27 |
Bayer Healthcare Ag |
Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist
|
|
JP2004161716A
(ja)
|
2002-11-15 |
2004-06-10 |
Takeda Chem Ind Ltd |
Ｊｎｋ阻害剤
|
|
EP1594512A4
(en)
|
2003-02-11 |
2007-07-11 |
Kemia Inc |
COMPOUNDS FOR THE TREATMENT OF VIRUS INFECTIONS
|
|
DE10306250A1
(de)
|
2003-02-14 |
2004-09-09 |
Aventis Pharma Deutschland Gmbh |
Substituierte N-Arylheterozyklen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
|
|
EA200501607A1
(ru)
|
2003-04-14 |
2006-06-30 |
ДЗЕ ИНСТИТЬЮТС ФОР ФАРМАСЬЮТИКАЛ ДИСКАВЕРИ, ЭлЭлСи |
Замещённые фенилалкановые кислоты
|
|
WO2005000813A1
(en)
|
2003-05-30 |
2005-01-06 |
Imclone Systems Incorporated |
Heteroarylamino-phenylketone derivatives and their use as kinase inhibitors
|
|
WO2005012293A1
(ja)
|
2003-08-01 |
2005-02-10 |
Nippon Soda Co., Ltd. |
フェニルアゾール化合物、製造法および抗酸化薬
|
|
AU2004268948A1
(en)
|
2003-08-21 |
2005-03-10 |
Osi Pharmaceuticals, Inc. |
N-substituted pyrazolyl-amidyl-benzimidazolyl c-kit inhibitors
|
|
US7485658B2
(en)
|
2003-08-21 |
2009-02-03 |
Osi Pharmaceuticals, Inc. |
N-substituted pyrazolyl-amidyl-benzimidazolyl c-Kit inhibitors
|
|
EP1663204B1
(en)
|
2003-08-29 |
2014-05-07 |
Exelixis, Inc. |
C-kit modulators and methods of use
|
|
EP1786815B1
(en)
|
2003-09-10 |
2011-08-24 |
Virochem Pharma Inc. |
Spiro compounds and methods for the modulation of chemokine receptor activity
|
|
US7211671B2
(en)
|
2003-10-01 |
2007-05-01 |
Bristol Myers Squibb Company |
Substituted 1,3-dihydro-imidazol-2-one and 1,3-dihydro-imidazol-2-thione derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
|
|
CA2541458C
(en)
|
2003-10-08 |
2011-09-20 |
Eli Lilly And Company |
Pyrrole and pyrazole derivatives as potentiators of glutamate receptors
|
|
US20050187409A1
(en)
|
2003-10-21 |
2005-08-25 |
Powers Gordon D. |
Inhibitors of RNase P proteins as antibacterial compounds
|
|
US20080275062A1
(en)
|
2004-01-30 |
2008-11-06 |
David Harold Drewry |
Chemical Compounds
|
|
EP1574502A1
(en)
|
2004-03-08 |
2005-09-14 |
Novartis AG |
Use of pyrimidine compounds in the preparation of parasiticides
|
|
CA2578789A1
(en)
|
2004-09-03 |
2006-03-16 |
Celgene Corporation |
Substituted heterocyclic compounds and uses thereof
|
|
EP1805136A1
(en)
|
2004-10-28 |
2007-07-11 |
The Institutes for Pharmaceutical Discovery, LLC |
Substituted phenylalkanoic acids
|
|
CA2589827A1
(en)
|
2004-12-21 |
2006-06-29 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
US8329703B2
(en)
|
2005-02-15 |
2012-12-11 |
Xtl Biopharmaceuticals Ltd. |
Pyrazole compounds
|
|
WO2006102645A1
(en)
|
2005-03-24 |
2006-09-28 |
Janssen Pharmaceutica, N.V. |
Biaryl derived amide modulators of vanilloid vr1 receptor
|
|
BRPI0612287A8
(pt)
|
2005-06-27 |
2019-01-22 |
Exelixis Inc |
composição para uso farmacêutico no tratamento de doenças através da medicina nuclear e métodos de uso e para modulação de atividade de receptor nuclear
|
|
FR2887548B1
(fr)
|
2005-06-27 |
2007-09-21 |
Sanofi Aventis Sa |
Derives de 4,5-diarylpyrrole, leur preparation et leur application en therapeutique
|
|
FR2888237B1
(fr)
|
2005-07-08 |
2007-08-31 |
Sanofi Aventis Sa |
Derives de n-[(4,5-diphenylpyrimidin-2-yl)methyl] amine, leur preparation et leur application en therapeutique
|
|
AR057450A1
(es)
|
2005-07-12 |
2007-12-05 |
Sanofi Aventis |
Derivados de n-[(1,2-difenil-1h-imidazol-4- il)metil]amina su preparacion y su aplicacion en terapeutica
|
|
BRPI0615133A2
(pt)
|
2005-08-23 |
2011-05-03 |
Irm Llc |
compostos imunossupressores, composições farmacêuticas contendo os mesmos assim como referido uso
|
|
US7906652B2
(en)
|
2005-11-28 |
2011-03-15 |
Merck Sharp & Dohme Corp. |
Heterocycle-substituted 3-alkyl azetidine derivatives
|
|
FR2894578B1
(fr)
|
2005-12-12 |
2008-02-01 |
Sanofi Aventis Sa |
Derives heterocycliques, leur preparation et leur application en therapeutique.
|
|
FR2894579B1
(fr)
|
2005-12-12 |
2008-01-18 |
Sanofi Aventis Sa |
Derives diaryltriazolmethylamine, leur preparation et leur application en therapeutique.
|
|
US20090042926A1
(en)
|
2005-12-20 |
2009-02-12 |
Jason Imbriglio |
Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment
|
|
EA200870117A1
(ru)
|
2005-12-23 |
2008-12-30 |
Смитклайн Бичам Корпорейшн |
Азаиндоловые ингибиторы аурора-киназ
|
|
CA2643963A1
(en)
|
2006-02-21 |
2007-08-30 |
Amgen Inc. |
Cinnoline derivatives as phosphodiesterase 10 inhibitors
|
|
AU2012200157B2
(en)
|
2006-05-25 |
2014-08-21 |
Synta Pharmaceuticals Corp. |
Method for treating proliferative disorders associated with protooncogene products
|
|
WO2007146230A2
(en)
|
2006-06-14 |
2007-12-21 |
Merck & Co., Inc. |
Non-nucleoside reverse transcriptase inhibitors
|
|
US9108948B2
(en)
|
2006-06-23 |
2015-08-18 |
Abbvie Inc. |
Cyclopropyl amine derivatives
|
|
CN101479249B
(zh)
|
2006-06-29 |
2012-10-10 |
霍夫曼-拉罗奇有限公司 |
苯并咪唑衍生物、其制备方法、它们作为fxr激动剂的用途及含有它们的药物制剂
|
|
CN101501023A
(zh)
|
2006-07-07 |
2009-08-05 |
贝林格尔.英格海姆国际有限公司 |
苯基取代的杂芳基衍生物及其作为抗肿瘤剂的用途
|
|
WO2008016643A2
(en)
|
2006-08-01 |
2008-02-07 |
Cytokinetics, Incorporated |
Certain chemical entities, compositions, and methods
|
|
FR2904827B1
(fr)
|
2006-08-11 |
2008-09-19 |
Sanofi Aventis Sa |
Derives de 5,6-bisaryl-2-pyridine-carboxamide, leur preparation et leur application en therapeutique comme antiganistes des recepteurs a l'urotensine ii
|
|
KR101104666B1
(ko)
|
2006-09-06 |
2012-01-13 |
에프. 호프만-라 로슈 아게 |
단백질 키나제 억제제로서의 헤테로아릴 유도체
|
|
WO2008057246A2
(en)
|
2006-10-26 |
2008-05-15 |
Synta Pharmaceuticals Corp. |
Method for treating inflammatory disorders
|
|
WO2008064317A1
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Lipophilic opioid receptor active compounds
|
|
WO2008064310A2
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Mixed opioid receptor active compounds
|
|
WO2008064318A2
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Peripheral opioid receptor active compounds
|
|
WO2008074703A1
(en)
|
2006-12-19 |
2008-06-26 |
F. Hoffmann-La Roche Ag |
Heteroaryl pyrrolidinyl and piperidinyl ketone derivatives
|
|
US8012955B2
(en)
|
2006-12-28 |
2011-09-06 |
Rigel Pharmaceuticals, Inc. |
N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
|
|
FR2911136B1
(fr)
|
2007-01-05 |
2009-02-20 |
Sanofi Aventis Sa |
Derives de n-(4-cyano-1h-pyrazol-3-yl)methylamine substitues leur preparation et leur application en therapeutique.
|
|
AU2008205642B2
(en)
|
2007-01-12 |
2013-06-06 |
Msd K.K. |
Spirochromanon derivatives
|
|
TW200838516A
(en)
|
2007-01-31 |
2008-10-01 |
Merck & Co Inc |
Substituted pyrano[2,3-B]pyridine derivatives as cannabinoid-1 receptor modulators
|
|
JP2008195655A
(ja)
|
2007-02-14 |
2008-08-28 |
Kitasato Institute |
糖尿病白内障の治療剤
|
|
WO2008137102A2
(en)
|
2007-05-04 |
2008-11-13 |
Torreypines Therapeutics, Inc. |
Methods of modulating amyloid beta and compounds useful therefor
|
|
EP1992625A1
(en)
|
2007-05-16 |
2008-11-19 |
Sanofi-Aventis |
Arylamide pyrimidone compounds
|
|
CA2687306A1
(en)
|
2007-05-18 |
2008-11-27 |
Bayer Schering Pharma Aktiengesellschaft |
Heteroaryl substituted pyrazole derivatives useful for treating hyper-proliferative disorders and diseases associated with angiogenesis
|
|
NZ580887A
(en)
|
2007-05-23 |
2012-03-30 |
Merck Sharp & Dohme |
Pyridyl piperidine orexin receptor antagonists
|
|
AR066834A1
(es)
|
2007-06-06 |
2009-09-16 |
Janssen Pharmaceutica Nv |
Espirobenzoazepanos como antagonistas de vasopresina, composiciones farmaceuticas que los contienen, proceso de preparacion y usos para el tratamiento de afecciones cardiacas, renales y del sistema nervioso central.
|
|
EP2002838A1
(de)
|
2007-06-13 |
2008-12-17 |
Bayer Schering Pharma AG |
Verwendung von Aryl/Hetarylamid-Derivaten als Modulatoren des EP2-Rezeptors
|
|
ATE520667T1
(de)
|
2007-06-15 |
2011-09-15 |
Basf Se |
Verfahren zur herstellung difluormethylsubstituierter pyrazolverbindungen
|
|
CA2692379A1
(en)
|
2007-07-02 |
2009-01-08 |
Boehringer Ingelheim International Gmbh |
Antiproliferative compounds based on 5-membered heterocycles
|
|
WO2009015208A1
(en)
|
2007-07-23 |
2009-01-29 |
Replidyne, Inc. |
Antibacterial amide and sulfonamide substituted heterocyclic urea compounds
|
|
WO2009042294A2
(en)
|
2007-08-10 |
2009-04-02 |
Burnham Institute For Medical Research |
Tissue-nonspecific alkaline phosphatase (tnap) activators and uses thereof
|
|
CN101903349B
(zh)
|
2007-08-27 |
2014-01-08 |
Abbvie德国有限责任两合公司 |
4-(4-吡啶基)-苯甲酰胺及其作为rock活性调节剂的应用
|
|
TW200920357A
(en)
|
2007-09-10 |
2009-05-16 |
Curis Inc |
HSP90 inhibitors containing a zinc binding moiety
|
|
WO2009036051A1
(en)
|
2007-09-10 |
2009-03-19 |
Curis, Inc. |
Bcl-2 inhibitors containing a zinc binding moiety
|
|
KR20090033583A
(ko)
|
2007-10-01 |
2009-04-06 |
주식회사 엘지생명과학 |
글라이신 아릴 아마이드를 포함하는 신규한베타-세크리타제 저해용 화합물
|
|
SI2212282T1
(sl)
|
2007-10-17 |
2012-01-31 |
Sanofi Sa |
Substituirani n-fenil-bipirolidin karboksamidi in njihova terapevtska uporaba
|
|
TWI440638B
(zh)
|
2007-10-30 |
2014-06-11 |
Otsuka Pharma Co Ltd |
雜環化合物及其藥學組成物
|
|
WO2009061676A2
(en)
|
2007-11-06 |
2009-05-14 |
Amira Pharmaceuticals, Inc. |
Antagonists of pgd2 receptors
|
|
EP2227471A1
(en)
|
2007-12-11 |
2010-09-15 |
Schering Corporation |
Gamma secretase modulators
|
|
WO2009079008A1
(en)
|
2007-12-19 |
2009-06-25 |
Yangbo Feng |
Benzopyrans and analogs as rho kinase inhibitors
|
|
JP2011507850A
(ja)
*
|
2007-12-21 |
2011-03-10 |
ザ スクリプス リサーチ インスティチュート |
Ｒｈｏキナーゼインヒビターとしてのアニリドおよびアナログ
|
|
CN101537006B
(zh)
|
2008-03-18 |
2012-06-06 |
中国科学院上海药物研究所 |
哒嗪酮类化合物在制备抗肿瘤药物中的用途
|
|
CA2721060A1
(en)
|
2008-04-09 |
2009-10-15 |
Infinity Pharmaceuticals, Inc. |
Inhibitors of fatty acid amide hydrolase
|
|
CN102015660A
(zh)
|
2008-04-23 |
2011-04-13 |
协和发酵麒麟株式会社 |
2-氨基喹唑啉衍生物
|
|
WO2009137657A1
(en)
|
2008-05-08 |
2009-11-12 |
Bristol-Myers Squibb Company |
2-aryl glycinamide derivatives
|
|
CN101597278B
(zh)
|
2008-06-04 |
2013-04-17 |
中国中化股份有限公司 |
酰胺类化合物及其制备与应用
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
US8623238B2
(en)
|
2008-06-27 |
2014-01-07 |
Transitions Optical, Inc. |
Mesogenic stabilizers
|
|
NZ603525A
(en)
|
2008-06-27 |
2015-02-27 |
Celgene Avilomics Res Inc |
Pyrimidine based compound and uses thereof
|
|
WO2010036316A1
(en)
|
2008-09-24 |
2010-04-01 |
Yangbo Feng |
Urea and carbamate compounds and analogs as kinase inhibitors
|
|
AU2009300318A1
(en)
|
2008-10-01 |
2010-04-08 |
Synta Pharmaceuticals Corp. |
Compounds for inflammation and immune-related uses
|
|
CN102264733B
(zh)
|
2008-10-10 |
2014-07-30 |
中国人民解放军军事医学科学院毒物药物研究所 |
新型多巴胺d3受体配体，其制备方法及其医药用途
|
|
US8367679B2
(en)
|
2008-12-09 |
2013-02-05 |
Merck Sharp & Dohme Corp. |
Biaryl carboxamides
|
|
JP2012512877A
(ja)
|
2008-12-18 |
2012-06-07 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
セロトニン５−ｈｔ２ｂ受容体阻害剤
|
|
WO2010075290A1
(en)
|
2008-12-22 |
2010-07-01 |
President And Fellows Of Harvard College |
Unsaturated heterocyclic inhibitors of necroptosis
|
|
US8785468B2
(en)
|
2009-02-13 |
2014-07-22 |
Amgen Inc. |
Phenylalanine amide derivatives useful for treating insulin-related diseases and conditions
|
|
JP5688918B2
(ja)
|
2009-04-28 |
2015-03-25 |
大塚製薬株式会社 |
医薬組成物
|
|
WO2010129848A2
(en)
|
2009-05-08 |
2010-11-11 |
Takeda Pharmaceutical Company Limited |
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamides
|
|
CA2765053C
(en)
|
2009-06-09 |
2015-08-18 |
California Capital Equity, Llc |
Isoquinoline, quinoline, and quinazoline derivatives as inhibitors of hedgehog signaling
|
|
TW201103904A
(en)
|
2009-06-11 |
2011-02-01 |
Hoffmann La Roche |
Janus kinase inhibitor compounds and methods
|
|
WO2011032169A2
(en)
|
2009-09-14 |
2011-03-17 |
Phusis Therapeutics Inc. |
Pharmaceutical compositions and formulations including inhibitors of the pleckstrin homology domain and methods for using same
|
|
WO2011041593A1
(en)
|
2009-09-30 |
2011-04-07 |
University Of Kansas |
Novobiocin analogues and treatment of polycystic kidney disease
|
|
US8377970B2
(en)
|
2009-10-08 |
2013-02-19 |
Rhizen Pharmaceuticals Sa |
Modulators of calcium release-activated calcium channel
|
|
US8993612B2
(en)
|
2009-10-08 |
2015-03-31 |
Rhizen Pharmaceuticals Sa |
Modulators of calcium release-activated calcium channel and methods for treatment of non-small cell lung cancer
|
|
EP2947082A1
(en)
|
2009-11-10 |
2015-11-25 |
Pfizer Inc |
N1-PYRAZOLOSPIROKETONE ACETYL-CoA CARBOXYLASE INHIBITORS
|
|
EP2499140A1
(en)
|
2009-11-10 |
2012-09-19 |
Pfizer Inc. |
N2-pyrazolospiroketone acetyl-coa carboxylase inhibitors
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
CN102812003B
(zh)
|
2009-12-18 |
2015-01-21 |
欧洲筛选有限公司 |
吡咯烷羧酸衍生物、药物组合物以及在代谢紊乱中作为g-蛋白偶联受体43(gpr43)激动剂使用的方法
|
|
JP2013047188A
(ja)
|
2009-12-24 |
2013-03-07 |
Nippon Chemiphar Co Ltd |
Ｇｐｒ１１９作動薬
|
|
AU2011205283B2
(en)
|
2010-01-13 |
2014-07-10 |
Tempero Pharmaceuticals, Inc. |
Compounds and methods
|
|
KR20120114355A
(ko)
|
2010-01-13 |
2012-10-16 |
글락소스미스클라인 엘엘씨 |
화합물 및 방법
|
|
WO2011088031A1
(en)
|
2010-01-13 |
2011-07-21 |
Glaxosmithkline Llc |
Compounds and methods
|
|
KR20120130104A
(ko)
|
2010-02-01 |
2012-11-28 |
닛뽕 케미파 가부시키가이샤 |
Ｇｐｒ119 작동약
|
|
WO2011099502A1
(ja)
|
2010-02-10 |
2011-08-18 |
公立大学法人横浜市立大学 |
神経選択的転写抑制因子NRSFに特異的に結合するmSin3B に結合する化合物の利用
|
|
WO2011106632A1
(en)
|
2010-02-26 |
2011-09-01 |
Millennium Pharmaceuticals, Inc. |
Substituted hydroxamic acids and uses thereof
|
|
CN102906080A
(zh)
|
2010-03-11 |
2013-01-30 |
百时美施贵宝公司 |
治疗丙型肝炎的化合物
|
|
US8354410B2
(en)
|
2010-03-11 |
2013-01-15 |
Bristol-Meyers Squibb Company |
Compounds for the treatment of hepatitis C
|
|
US8598164B2
(en)
|
2010-05-06 |
2013-12-03 |
Vertex Pharmaceuticals Incorporated |
Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
|
|
WO2011156557A2
(en)
|
2010-06-11 |
2011-12-15 |
Thomas James B |
Compounds active at the neurotensin receptor
|
|
US9079880B2
(en)
|
2010-07-07 |
2015-07-14 |
Boehringer Ingelheim International Gmbh |
Rho kinase inhibitors
|
|
US8697911B2
(en)
|
2010-07-07 |
2014-04-15 |
Boehringer Ingelheim International Gmbh |
Rho kinase inhibitors
|
|
KR101541086B1
(ko)
|
2010-08-20 |
2015-08-03 |
허치슨 메디파르마 리미티드 |
피롤로피리미딘 화합물 및 그 용도
|
|
WO2012040444A2
(en)
|
2010-09-24 |
2012-03-29 |
Bristol-Myers Squibb Company |
Treatment of patients with incipient alzheimer's disease
|
|
AU2011313853A1
(en)
|
2010-10-11 |
2013-05-02 |
Auckland Uniservices Limited |
Substituted benzamides and their uses
|
|
CN102451178A
(zh)
|
2010-10-29 |
2012-05-16 |
中国科学院上海药物研究所 |
二氢呋喃-2-酮类化合物在制备抗糖尿病及糖脂代谢药物中的用途
|
|
US20120129843A1
(en)
|
2010-11-18 |
2012-05-24 |
Yan Zhang |
Pyridyl-thiazolyl inhibitors of pro-matrix metalloproteinase activation
|
|
BR112013012719A2
(pt)
|
2010-11-22 |
2019-09-24 |
Allergan Inc |
"compostos como moduladores de receptor com utilidade terapêutica".
|
|
EP2457900A1
(en)
|
2010-11-25 |
2012-05-30 |
Almirall, S.A. |
New pyrazole derivatives having CRTh2 antagonistic behaviour
|
|
ES2541289T3
(es)
|
2010-12-01 |
2015-07-17 |
Nissan Chemical Industries, Ltd. |
Compuestos de pirazol que tienen un efecto terapéutico sobre mieloma múltiple
|
|
WO2012074068A1
(ja)
|
2010-12-01 |
2012-06-07 |
日産化学工業株式会社 |
ピラゾール化合物による造血幹細胞の製造方法
|
|
KR20130126659A
(ko)
|
2010-12-07 |
2013-11-20 |
아미라 파마슈티칼스 인코포레이티드 |
리소포스파티드산 수용체 길항제 및 섬유증 치료에서의 그의 용도
|
|
GB201021104D0
(en)
|
2010-12-13 |
2011-01-26 |
Univ Leuven Kath |
Novel compounds for the treatment of neurodegenerative diseases
|
|
KR101923367B1
(ko)
|
2011-02-02 |
2018-12-04 |
버텍스 파마슈티칼스 인코포레이티드 |
이온 채널의 조절제로서의 피롤로피라진―스피로사이클릭 피페리딘 아미드
|
|
GB201104267D0
(en)
|
2011-03-14 |
2011-04-27 |
Cancer Rec Tech Ltd |
Pyrrolopyridineamino derivatives
|
|
TWI572599B
(zh)
|
2011-03-28 |
2017-03-01 |
Ｍｅｉ製藥公司 |
（α－經取代之芳烷胺基及雜芳烷胺基）嘧啶基及１，３，５－三基苯并咪唑，其醫藥組合物及其在治療增生性疾病之用途
|
|
US9616064B2
(en)
|
2011-03-30 |
2017-04-11 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Rho kinase inhibitors and methods of use
|
|
GB201107223D0
(en)
|
2011-04-29 |
2011-06-15 |
Amakem Nv |
Novel rock inhibitors
|
|
JP2014515368A
(ja)
|
2011-05-26 |
2014-06-30 |
第一三共株式会社 |
プロテインキナーゼ阻害剤としての複素環化合物
|
|
BR112013030163A2
(pt)
|
2011-05-26 |
2017-03-01 |
Tfchem |
composto, uso cosmético de pelo menos um composto, composição farmacêutica ou cosmética e processo para preparar um composto.
|
|
CN103748070B
(zh)
|
2011-05-31 |
2015-06-24 |
施万生物制药研发Ip有限责任公司 |
脑啡肽酶抑制剂
|
|
ES2561298T3
(es)
|
2011-07-12 |
2016-02-25 |
F. Hoffmann-La Roche Ag |
Compuestos de aminometilquinolona
|
|
JP5967092B2
(ja)
|
2011-07-29 |
2016-08-10 |
日本ゼオン株式会社 |
光学異方体の波長分散調整方法及び重合性組成物
|
|
WO2013067248A1
(en)
|
2011-11-04 |
2013-05-10 |
Vertex Pharmaceuticals Incorporated |
Benzoxazines as modulators of ion channels
|
|
EA201590197A1
(ru)
*
|
2012-08-23 |
2015-07-30 |
Алиос Биофарма, Инк. |
Соединения для лечения парамиксовирусных вирусных инфекций
|
|
WO2014079850A1
(en)
*
|
2012-11-23 |
2014-05-30 |
F. Hoffmann-La Roche Ag |
Substituted heterocyclic derivatives
|
|
CA2898440A1
(en)
|
2013-01-18 |
2014-07-24 |
Bristol-Myers Squibb Company |
Phthalazinones and isoquinolinones as rock inhibitors
|
|
CN105102448B
(zh)
|
2013-02-28 |
2018-03-06 |
百时美施贵宝公司 |
作为rock1和rock2抑制剂的苯基吡唑衍生物
|
|
WO2015002926A1
(en)
|
2013-07-02 |
2015-01-08 |
Bristol-Myers Squibb Company |
Tricyclic pyrido-carboxamide derivatives as rock inhibitors
|
|
AR096788A1
(es)
|
2013-07-02 |
2016-02-03 |
Bristol Myers Squibb Co |
Compuestos tricíclicos de carboxamida como inhibidores potentes de rock
|
|
KR101861942B1
(ko)
|
2014-01-20 |
2018-06-29 |
에프. 호프만-라 로슈 아게 |
신경 발생을 자극할 수 있는 n-페닐-락탐 유도체 및 이의 신경 장애 치료에서의 용도
|