AU2002248432A1 - Oxazole derivatives, their preparation and their use as cytokine inhibitors - Google Patents

Oxazole derivatives, their preparation and their use as cytokine inhibitors

Info

Publication number
AU2002248432A1
AU2002248432A1 AU2002248432A AU2002248432A AU2002248432A1 AU 2002248432 A1 AU2002248432 A1 AU 2002248432A1 AU 2002248432 A AU2002248432 A AU 2002248432A AU 2002248432 A AU2002248432 A AU 2002248432A AU 2002248432 A1 AU2002248432 A1 AU 2002248432A1
Authority
AU
Australia
Prior art keywords
preparation
oxazole derivatives
cytokine inhibitors
cytokine
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002248432A
Inventor
Douglas Burdi
Corinna Grisostomi
Shunji Naruto
Alexander Porte
Yuichi Sugano
Tohru Tatsuta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of AU2002248432A1 publication Critical patent/AU2002248432A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002248432A 2001-02-14 2002-02-13 Oxazole derivatives, their preparation and their use as cytokine inhibitors Abandoned AU2002248432A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26877101P 2001-02-14 2001-02-14
US60/268,771 2001-02-14
PCT/US2002/004326 WO2002064558A2 (en) 2001-02-14 2002-02-13 Oxazole derivatives, their preparation and their use as cytokine inhibitors

Publications (1)

Publication Number Publication Date
AU2002248432A1 true AU2002248432A1 (en) 2002-08-28

Family

ID=23024411

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002248432A Abandoned AU2002248432A1 (en) 2001-02-14 2002-02-13 Oxazole derivatives, their preparation and their use as cytokine inhibitors

Country Status (2)

Country Link
AU (1) AU2002248432A1 (en)
WO (1) WO2002064558A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4617449B2 (en) 2002-07-11 2011-01-26 ヴィキュロン ファーマシューティカルズ インコーポレイテッド N-hydroxyamide derivative having antibacterial activity
EP1637529A1 (en) * 2004-09-20 2006-03-22 4Sc Ag Novel piperidin-4-yl-thiazole-carboxamide analogues as inhibitors of T-cell proliferation and uses thereof
TW200738701A (en) * 2005-07-26 2007-10-16 Du Pont Fungicidal carboxamides
NZ565470A (en) * 2005-07-29 2010-11-26 4Sc Ag Novel heterocyclic NF-kB inhibitors
US8741960B2 (en) 2006-01-25 2014-06-03 Synta Pharmaceuticals Corp. Substituted aromatic compounds for inflammation and immune-related uses
WO2007087429A2 (en) * 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Phenyl and pyridyl compounds for inflammation and immune-related uses
EA200801838A1 (en) * 2006-03-15 2009-02-27 4ЭсЦэ АГ NEW HETEROCYCLIC INHIBITORS NF-kB
EP2009005A4 (en) 2006-04-19 2010-06-02 Astellas Pharma Inc Azolecarboxamide derivative
KR20100059919A (en) 2007-09-24 2010-06-04 코멘티스, 인코포레이티드 (3-hydroxy-4-amino-butan-2-yl)-3-(2-thiazol-2-yl-pyrrolidine-1-carbonyl) benzamide derivatives and related compounds as beta-secretase inhibitors for treating
PL2206707T3 (en) 2007-10-24 2015-01-30 Astellas Pharma Inc Azolecarboxamide compound or salt thereof
PT2763979T (en) 2011-10-07 2019-04-12 Takeda Pharmaceuticals Co 1 - arylcarbonyl - 4 - oxy - piperidine compounds useful for the treatment of neurodegenerative diseases
EP2961746B1 (en) 2013-02-28 2018-01-03 Bristol-Myers Squibb Company Phenylpyrazole derivatives as potent rock1 and rock2 inhibitors
TW201444798A (en) 2013-02-28 2014-12-01 必治妥美雅史谷比公司 Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors
AU2022283883A1 (en) * 2021-06-01 2023-12-21 Azcuris Co., Ltd. Novel oxazole derivative and pharmaceutical composition containing same for prevention or treatment of allergic disease

Also Published As

Publication number Publication date
WO2002064558A2 (en) 2002-08-22
WO2002064558A3 (en) 2003-11-20

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase