AU2001244355A1 - Heterobiarylsulphonamides and their use as pde 7 inhibitors - Google Patents

Heterobiarylsulphonamides and their use as pde 7 inhibitors

Info

Publication number
AU2001244355A1
AU2001244355A1 AU2001244355A AU4435501A AU2001244355A1 AU 2001244355 A1 AU2001244355 A1 AU 2001244355A1 AU 2001244355 A AU2001244355 A AU 2001244355A AU 4435501 A AU4435501 A AU 4435501A AU 2001244355 A1 AU2001244355 A1 AU 2001244355A1
Authority
AU
Australia
Prior art keywords
heterobiarylsulphonamides
pde
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001244355A
Inventor
Hazel Joan Dyke
Frances Celia Anne Galvin
Alan Findlay Haughan
Christopher Lowe
Trevor Morgan
Catherine Louise Picken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of AU2001244355A1 publication Critical patent/AU2001244355A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D263/57—Aryl or substituted aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
AU2001244355A 2000-03-31 2001-03-30 Heterobiarylsulphonamides and their use as pde 7 inhibitors Abandoned AU2001244355A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0007934 2000-03-31
GBGB0007934.3A GB0007934D0 (en) 2000-03-31 2000-03-31 Chemical compounds
PCT/GB2001/001479 WO2001074786A1 (en) 2000-03-31 2001-03-30 Heterobiarylsulphonamides and their use as pde 7 inhibitors

Publications (1)

Publication Number Publication Date
AU2001244355A1 true AU2001244355A1 (en) 2001-10-15

Family

ID=9888912

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001244355A Abandoned AU2001244355A1 (en) 2000-03-31 2001-03-30 Heterobiarylsulphonamides and their use as pde 7 inhibitors

Country Status (3)

Country Link
AU (1) AU2001244355A1 (en)
GB (1) GB0007934D0 (en)
WO (1) WO2001074786A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040031782A (en) * 2001-07-27 2004-04-13 쿠리스 인코퍼레이션 Mediators of Hedgehog Signaling Pathways, Compositions and Uses Related Thereto
ATE369854T1 (en) * 2001-10-19 2007-09-15 Ortho Mcneil Pharm Inc 2-PHENYL BENZIMIDAZOLE AND IMIDAZO-[4,5]-PYRIDINES AS CDS1/CHK2 INHIBITORS AND ADJUVANTS IN CHEMOTHERAPY OR RADIATION THERAPY FOR THE TREATMENT OF CANCER
US7378428B2 (en) * 2002-01-31 2008-05-27 Ono Pharmaceutical Co., Ltd. Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient
ATE405840T1 (en) 2002-12-19 2008-09-15 Scripps Research Inst COMPOSITIONS AND METHODS FOR STABILIZING TRANSTHYRETIN AND INHIBITING TRANSTHYRETIN MISFOLDING
WO2004093873A1 (en) 2003-04-17 2004-11-04 Janssen Pharmaceutica, N.V. 2-phenyl-benzimidazol and 2-phenyl-imidazo-`4,5!-pyridine derivatives as checkpoint kinase cds1 (chk2) inhibitors for the treatment of cancer
JP2006219373A (en) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Pyridinylpyrazolopyrimidinone derivative having pde 7 inhibition
JP2006219374A (en) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Imidazotriazinone derivative having pde 7 inhibition
JP2007513184A (en) 2003-12-04 2007-05-24 バーテックス　ファーマシューティカルズ　インコーポレイテッド Quinoxaline useful as an inhibitor of protein kinase
DE102004010207A1 (en) 2004-03-02 2005-09-15 Aventis Pharma S.A. New 4-benzimidazolyl-3(2H)-pyridazinone derivatives are kinase inhibitors, especially useful for treatment of cancer
DE102004010194A1 (en) * 2004-03-02 2005-10-13 Aventis Pharma Deutschland Gmbh 4-Benzimidazol-2-yl-pyridazin-3-one derivatives, their preparation and use in medicaments
US7262318B2 (en) 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20080319175A1 (en) 2004-05-20 2008-12-25 The Scripps Research Institute Transthyretin Stabilization
CN1976938B (en) 2004-07-01 2012-08-15 第一三共株式会社 Thienopyrazole derivative having PDE7 inhibitory activity
EP3088400A1 (en) * 2005-06-22 2016-11-02 Plexxikon Inc. Pyrrolo[2,3-b]pyridine derivatives as protein kinase inhibitors
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
US8637528B2 (en) 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
US20080260643A1 (en) 2007-03-27 2008-10-23 Omeros Corporation Use of pde7 inhibitors for the treatment of movement disorders
NZ582772A (en) 2007-07-17 2012-06-29 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
EA031116B1 (en) 2009-04-03 2018-11-30 Ф. Хоффманн-Ля Рош Аг PROPANE-1-SULFONIC ACID {3-[5-(4-CHLORO-PHENYL)-1H-PYRROLO[2,3-b]PYRIDINE-3-CARBONYL]-2,4-DIFLUORO-PHENYL}AMIDE CRYSTALLINE POLYMORPH FORMS
MX2012005284A (en) 2009-11-06 2012-06-28 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor.
AR082974A1 (en) 2010-09-15 2013-01-23 Hoffmann La Roche DERIVATIVES OF AZABENZOTIAZOL, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, METHOD TO PREPARE THEM AND USE OF THEM TO TREAT INFLAMMATORY DISEASES
CN106038567A (en) 2010-11-08 2016-10-26 奥默罗斯公司 Treatment of addiction and impulse-control disorders using pde7 inhibitors
US9220715B2 (en) 2010-11-08 2015-12-29 Omeros Corporation Treatment of addiction and impulse-control disorders using PDE7 inhibitors
PT2672967T (en) 2011-02-07 2018-12-07 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
TWI558702B (en) 2011-02-21 2016-11-21 普雷辛肯公司 Solid forms of a pharmaceutically active substance
CN103781770B (en) 2011-09-16 2016-04-13 辉瑞公司 Transthyretin dissociates the solid form of inhibitor
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
WO2024038090A1 (en) 2022-08-18 2024-02-22 Mitodicure Gmbh Use of substituted benzoxazole and benzofuran compounds for the treatment and prevention of diseases associated with chronic fatigue, exhaustion and/or exertional intolerance

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0946541B1 (en) * 1996-11-06 2003-07-30 Darwin Discovery Limited Quinolines and their therapeutic use
AU4501199A (en) * 1998-06-03 1999-12-20 Almirall Prodesfarma S.A. 8-phenylxanthine derivatives and their use as phosphodiesterase inhibitors

Also Published As

Publication number Publication date
WO2001074786A1 (en) 2001-10-11
GB0007934D0 (en) 2000-05-17

Similar Documents

Publication Publication Date Title
AU2001244355A1 (en) Heterobiarylsulphonamides and their use as pde 7 inhibitors
AU7392101A (en) 8-quinolinxanthine and 8-isoquinolinxanthine derivatives as pde 5 inhibitors
AU2001240542A1 (en) Heterocyclic compounds and their use as parp inhibitors
AU2001249969A1 (en) Inha inhibitors and their use as antibacterials
AU2001265008A1 (en) Caspase inhibitors and uses thereof
HK1053124A1 (en) Substituted quinazoline derivatives and their use as inhibitors
AU2002226487A1 (en) Novel c-glycoside derivatives and use thereof
GB0025782D0 (en) Use of inhibitors
AU2001270260A1 (en) 4-heteroaryl-3-heteroarylidenyl-2-indolinones and their use as protein kinase inhibitors
AU2002225954A1 (en) Dipeptidylpeptidases and methods of use
AU2001249284A1 (en) L-arginine and phosphodiesterase (pde) inhibitor synergism
AU2002227985A1 (en) Pyrrolo (2.1-a) dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
AU2002230836A1 (en) Benzylamine derivatives and their use as thrombin inhibitors
AU2002248269A1 (en) Use of p38 inhibitors for the treatment of inflammation-enhanced cough
AU2002213346A1 (en) Osteopontin-coated surfaces and methods of use
AU2001292047A1 (en) Composition containing an azaphthalocyanine and use
PL361733A1 (en) Sulfamidothienopyrimidines and the use of the same as phosphodiesterase v inhibitors
AU2001276027A1 (en) Heteroaryl-beta-alanine derivatives as alpha 4 integrin inhibitors
AU4501199A (en) 8-phenylxanthine derivatives and their use as phosphodiesterase inhibitors
AU2002216650A1 (en) Triazine derivatives as lpaat-b inhibitors and uses thereof
AU2001293048A1 (en) Antiviral compositions and methods of use
AU2001232809A1 (en) Gyrase inhibitors and uses thereof
AU2001266124A1 (en) 2-aminothiazoline derivatives and their use as no-synthase inhibitors
AU1039801A (en) Compounds and their use as cysteine protease inhibitors
AU4432001A (en) Trityl-type compounds and their use