|
HU168036B
(https=)
|
1973-11-09 |
1976-02-28 |
|
|
|
HU168776B
(https=)
|
1973-11-09 |
1976-07-28 |
|
|
|
CA1098910A
(en)
|
1978-06-15 |
1981-04-07 |
Robert N. Schut |
3-amino-2-(5-fluoro and 5-methoxy-1h-indol-3-yl) propanoic acid derivatives
|
|
JPS57116067A
(en)
|
1981-01-12 |
1982-07-19 |
Sankyo Kagaku Kk |
Novel 8-quinolinesulfonyl derivative, its synthesis and use
|
|
DE3703435A1
(de)
|
1987-02-05 |
1988-08-18 |
Thomae Gmbh Dr K |
Neue thiazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
IE68593B1
(en)
|
1989-12-06 |
1996-06-26 |
Sanofi Sa |
Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
|
|
US5945380A
(en)
|
1995-05-26 |
1999-08-31 |
Bayer Aktiengesellschaft |
Pyridyl-thiazoles and their use to protect plants against infections by micro-organisms
|
|
CA2276034A1
(en)
|
1996-12-23 |
1998-07-02 |
Mimi Lifen Quan |
Oxygen or sulfur containing 5-membered heteroaromatics as factor xa inhibitors
|
|
US6187797B1
(en)
|
1996-12-23 |
2001-02-13 |
Dupont Pharmaceuticals Company |
Phenyl-isoxazoles as factor XA Inhibitors
|
|
DE69821132T2
(de)
|
1997-10-27 |
2004-10-21 |
Takeda Chemical Industries Ltd |
1,3-thiazole als adenosine a3 rezeptor antagonisten zur behandlung von asthma, allergien und diabetes
|
|
AU3702699A
(en)
|
1998-04-08 |
1999-11-01 |
Bayer Aktiengesellschaft |
Substituted oxazolyle and thiazolyl uracil herbicides
|
|
KR20020069183A
(ko)
|
1999-07-26 |
2002-08-29 |
시오노기세이야쿠가부시키가이샤 |
트롬보포이에틴 작동성을 나타내는 의약 조성물
|
|
WO2001068648A1
(en)
|
2000-03-15 |
2001-09-20 |
Aventis Pharma Deutschland Gmbh |
Substituted beta-carbolines with ikb-kinase inhibiting activity
|
|
HUP0300894A3
(en)
*
|
2000-03-15 |
2008-05-28 |
Sanofi Aventis Deutschland |
Substituted beta-carbolines, process for their preparation, pharmaceutical compositions containing them and their use
|
|
GB0010183D0
(en)
|
2000-04-26 |
2000-06-14 |
Ferring Bv |
Inhibitors of dipeptidyl peptidase IV
|
|
JP2002053566A
(ja)
|
2000-08-11 |
2002-02-19 |
Japan Tobacco Inc |
チアゾール化合物及びその医薬用途
|
|
US6787552B2
(en)
|
2000-08-11 |
2004-09-07 |
Nippon Chemiphar Co., Ltd. |
PPAR delta activators
|
|
US20020173507A1
(en)
|
2000-08-15 |
2002-11-21 |
Vincent Santora |
Urea compounds and methods of uses
|
|
US20020103192A1
(en)
|
2000-10-26 |
2002-08-01 |
Curtin Michael L. |
Inhibitors of histone deacetylase
|
|
EP1354603A1
(en)
|
2000-12-26 |
2003-10-22 |
Takeda Chemical Industries, Ltd. |
Concomitant drugs
|
|
JPWO2002062775A1
(ja)
|
2001-02-02 |
2004-06-10 |
山之内製薬株式会社 |
2−アシルアミノチアゾール誘導体又はその塩
|
|
MY130778A
(en)
|
2001-02-09 |
2007-07-31 |
Vertex Pharma |
Heterocyclic inhibitiors of erk2 and uses thereof
|
|
US20020177594A1
(en)
|
2001-03-14 |
2002-11-28 |
Curtin Michael L. |
Inhibitors of histone deacetylase
|
|
JP4157381B2
(ja)
|
2001-03-23 |
2008-10-01 |
日本ケミファ株式会社 |
ペルオキシソーム増殖剤応答性受容体の活性化剤
|
|
JPWO2002087589A1
(ja)
|
2001-04-26 |
2004-08-12 |
第一製薬株式会社 |
薬剤排出ポンプ阻害薬
|
|
CA2450400A1
(en)
|
2001-06-11 |
2002-12-19 |
Takeda Chemical Industries, Ltd. |
Medicinal compositions
|
|
GB0123589D0
(en)
|
2001-10-01 |
2001-11-21 |
Syngenta Participations Ag |
Organic compounds
|
|
WO2003048140A1
(en)
|
2001-12-03 |
2003-06-12 |
Japan Tobacco Inc. |
Azole compound and medicinal use thereof
|
|
DK1466912T3
(da)
|
2002-01-18 |
2013-07-01 |
Astellas Pharma Inc |
2-acylaminothiazolderivat eller salt deraf
|
|
EP1467981A1
(en)
|
2002-01-25 |
2004-10-20 |
Kylix Pharmaceuticals B.V. |
4(hetero-) aryl substituted (thia-/oxa-/pyra) zoles for inhibition of tie-2
|
|
CA2484233A1
(en)
|
2002-05-13 |
2003-11-27 |
Eli Lilly And Company |
Multicyclic compounds for use as melanin concentrating hormone antagonists in the treatment of obesity and diabetes
|
|
WO2004009017A2
(en)
|
2002-07-18 |
2004-01-29 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
|
MXPA05001592A
(es)
|
2002-08-09 |
2005-05-05 |
Astrazeneca Ab |
Oxadiazoles como moduladores de receptor-5 de glutamato metabotropico.
|
|
EP1534680B1
(en)
|
2002-08-14 |
2012-02-22 |
Pharmaco Investments, Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
|
EP1558607B1
(en)
|
2002-10-30 |
2010-05-05 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of rock and other protein kinases
|
|
GB0230087D0
(en)
|
2002-12-24 |
2003-01-29 |
Astrazeneca Ab |
Therapeutic agents
|
|
GB0302672D0
(en)
|
2003-02-06 |
2003-03-12 |
Astrazeneca Ab |
Pharmaceutical formulations
|
|
WO2004071509A1
(ja)
|
2003-02-12 |
2004-08-26 |
Nippon Chemiphar Co., Ltd. |
オリゴデンドロサイト分化促進剤
|
|
SI1611088T1
(sl)
|
2003-04-07 |
2009-12-31 |
Pharmacyclics Inc |
Hidroksamati kot terapevtska sredstva
|
|
EP1613590A2
(en)
|
2003-04-16 |
2006-01-11 |
Memory Pharmaceutical Corporation |
4-(3,4-disubstituted phenyl)-pyrrolidin-2-one compounds as phosphodiesterase 4 inhibitors
|
|
CN100545161C
(zh)
|
2003-08-15 |
2009-09-30 |
中国科学院上海药物研究所 |
一类杂环衍生物、制备方法及其用途
|
|
US7351727B2
(en)
|
2003-09-02 |
2008-04-01 |
Bristol-Myers Squibb Company |
Inhibitors of 15-lipoxygenase
|
|
RU2006111093A
(ru)
|
2003-09-06 |
2007-10-27 |
Вертекс Фармасьютикалз Инкорпорейтед (Us) |
Модуляторы атр-связывающих кассетных транспортеров
|
|
TWI336697B
(en)
|
2003-09-19 |
2011-02-01 |
Solvay Pharm Bv |
Thiazole derivatives as cannabinoid receptor modulators
|
|
WO2005044194A2
(en)
|
2003-10-28 |
2005-05-19 |
Pharmacia Corporation |
TREATMENT OR PREVENTION OF NEOPLASIA BY USE OF AN Hsp90 INHIBITOR
|
|
MXPA06004657A
(es)
|
2003-10-28 |
2006-06-27 |
Pharmacia Corp |
Combinaciones que comprenden un inhibidor de hsp90 y un inhibidor de fosfodiesterasa para tratar o prevenir la neoplasia.
|
|
WO2005074643A2
(en)
|
2004-01-30 |
2005-08-18 |
Smithkline Beecham Corporation |
Benzamide compounds useful as rock inhibitors
|
|
BRPI0507278A
(pt)
|
2004-01-30 |
2007-06-26 |
Vertex Pharma |
moduladores dos transportadores do cassete de ligação ao atp
|
|
WO2005077345A1
(en)
|
2004-02-03 |
2005-08-25 |
Astrazeneca Ab |
Compounds for the treatment of gastro-esophageal reflux disease
|
|
WO2005077373A2
(en)
|
2004-02-03 |
2005-08-25 |
Astrazeneca Ab |
Treatment of gastro-esophageal reflux disease (gerd)
|
|
MY148488A
(en)
|
2004-02-18 |
2013-04-30 |
Astrazeneca Ab |
Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
|
|
WO2005077900A1
(ja)
|
2004-02-18 |
2005-08-25 |
Kyorin Pharmaceutical Co., Ltd. |
ビシクロアミド誘導体
|
|
US7259155B2
(en)
|
2004-05-05 |
2007-08-21 |
Otsuka Pharmaceutical Factory, Inc. |
Phosphonic diester derivatives
|
|
TW200637559A
(en)
|
2005-03-29 |
2006-11-01 |
Shionogi & Co |
3-propenylcefem derivative
|
|
FR2885129B1
(fr)
|
2005-04-29 |
2007-06-15 |
Proskelia Sas |
Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
|
|
NZ563866A
(en)
|
2005-05-09 |
2011-03-31 |
Achillion Pharmaceuticals Inc |
Thiazole compounds and methods of use
|
|
US7655446B2
(en)
|
2005-06-28 |
2010-02-02 |
Vertex Pharmaceuticals Incorporated |
Crystal structure of Rho-kinase I kinase domain complexes and binding pockets thereof
|
|
JP2009505948A
(ja)
*
|
2005-07-11 |
2009-02-12 |
デブジェン エヌブイ |
キナーゼ阻害剤としてのアミド誘導体
|
|
WO2007062222A2
(en)
|
2005-11-22 |
2007-05-31 |
University Of South Florida |
Inhibition of cell proliferation
|
|
WO2007075896A2
(en)
|
2005-12-22 |
2007-07-05 |
Kemia, Inc. |
Heterocyclic cytokine inhibitors
|
|
CA2639910A1
(en)
|
2006-01-25 |
2007-08-02 |
Synta Pharmaceuticals Corp. |
Thiazole and thiadiazole compounds for inflammation and immune-related uses
|
|
WO2007116106A1
(es)
|
2006-04-12 |
2007-10-18 |
Palobiofarma, S.L. |
Nuevos compuestos como antagonistas de los receptores a1 de adenosina
|
|
ATE478865T1
(de)
|
2006-05-12 |
2010-09-15 |
Vertex Pharma |
Selektive rock-proteinkinasehemmer und ihre verwendung
|
|
EP2081905B1
(en)
|
2006-07-28 |
2012-09-12 |
Boehringer Ingelheim International GmbH |
Sulfonyl compounds which modulate the cb2 receptor
|
|
CA2664310A1
(en)
|
2006-09-25 |
2008-04-03 |
Boehringer Ingelheim International Gmbh |
Compounds which modulate the cb2 receptor
|
|
TW200831081A
(en)
|
2006-12-25 |
2008-08-01 |
Kyorin Seiyaku Kk |
Glucokinase activator
|
|
WO2008124000A2
(en)
|
2007-04-02 |
2008-10-16 |
Ligand Pharmaceuticals Incorporated |
Thiazole derivatives as androgen receptor modulator compounds
|
|
GB0706793D0
(en)
|
2007-04-05 |
2007-05-16 |
Evotec Ag |
Compounds
|
|
JP2010530901A
(ja)
|
2007-06-22 |
2010-09-16 |
ハイドラ バイオサイエンシズ インコーポレイテッド |
障害を治療するための方法および組成物
|
|
US8445686B2
(en)
|
2007-08-27 |
2013-05-21 |
Abbvie Inc. |
4-(4-pyridinyl)-benzamides and their use as rock activity modulators
|
|
TW200916447A
(en)
|
2007-08-29 |
2009-04-16 |
Methylgene Inc |
Sirtuin inhibitors
|
|
ES2331220B1
(es)
|
2007-10-02 |
2010-09-23 |
Palobiofarma, S.L. |
Nuevos compuestos como antagonistas de los receptores a1 de adenosina.
|
|
RU2010121763A
(ru)
|
2007-10-31 |
2011-12-10 |
Ниссан Кемикал Индастриз, Лтд. (Jp) |
Производные пиридазинона и ингибиторы р2х7 рецептора
|
|
JP5492092B2
(ja)
|
2007-11-07 |
2014-05-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Cb2受容体を調節する化合物
|
|
WO2009067607A2
(en)
|
2007-11-20 |
2009-05-28 |
Memory Pharmaceuticals Corporation |
Combinations of pde4 inhibitors and antipsychotics for the treatment of psychotic disorders
|
|
WO2009081222A1
(en)
|
2007-12-21 |
2009-07-02 |
Glenmark Pharmaceuticals, S.A. |
Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands
|
|
CA2709784A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
CN101965176B
(zh)
|
2008-02-08 |
2012-06-20 |
株式会社资生堂 |
美白剂和皮肤外用剂
|
|
US20110105436A1
(en)
|
2008-03-10 |
2011-05-05 |
Auckland Uniservices Limited |
Heteroaryl compounds, compositions, and methods of use in cancer treatment
|
|
US20120108614A1
(en)
|
2008-05-14 |
2012-05-03 |
Chong Jayhong A |
Compounds and compositions for treating chemical warfare agent-induced injuries
|
|
WO2010028193A1
(en)
|
2008-09-03 |
2010-03-11 |
Repligen Corporation |
Compounds including pimelic acid derivatives as hdac inhibitors
|
|
US20100063085A1
(en)
*
|
2008-09-11 |
2010-03-11 |
University Court Of The University Of Dundee |
Method of treating learning impairment in down's syndrome subjects
|
|
WO2010029300A1
(en)
|
2008-09-12 |
2010-03-18 |
Biolipox Ab |
Bis aromatic compounds for use in the treatment of inflammation
|
|
US20120046305A1
(en)
|
2008-09-24 |
2012-02-23 |
Moran Magdalene M |
Methods and compositions for treating respiratory disorders
|
|
US8815840B2
(en)
*
|
2008-12-19 |
2014-08-26 |
Bristol-Myers Squibb Company |
Carbazole and carboline kinase inhibitors
|
|
HUE015568T4
(en)
|
2008-12-19 |
2017-10-30 |
Elanco Tiergesundheit Ag |
Isoxazoline derivatives and their use as pesticides
|
|
CA2740193A1
(en)
|
2008-12-23 |
2010-07-01 |
Abbott Laboratories |
Anti-viral compounds
|
|
JP2012051804A
(ja)
*
|
2008-12-26 |
2012-03-15 |
Kyoto Univ |
Eg5阻害剤
|
|
UA103918C2
(en)
|
2009-03-02 |
2013-12-10 |
Айерем Элелси |
N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators
|
|
US8362249B2
(en)
|
2009-04-27 |
2013-01-29 |
Boehringer Ingelheim International Gmbh |
CXCR3 receptor antagonists
|
|
CN102573487A
(zh)
|
2009-06-09 |
2012-07-11 |
加利福尼亚资本权益有限责任公司 |
Hedgehog信号传导的吡啶基-三嗪抑制剂
|
|
PL2470173T3
(pl)
|
2009-08-25 |
2016-11-30 |
|
Leczenie skojarzone nanocząstkowymi kompozycjami taksanu i inhibitorów hedgehog
|
|
CN102753544A
(zh)
*
|
2009-11-17 |
2012-10-24 |
密执安大学评议会 |
具有治疗性能的1,4-苯并二氮杂*-2,5-二酮和相关化合物
|
|
EP2512466A4
(en)
|
2009-12-18 |
2013-07-03 |
Activesite Pharmaceuticals Inc |
PRODRUGS OF INHIBITORS OF PLASMATIC KALLICREIN
|
|
WO2011129095A1
(ja)
|
2010-04-12 |
2011-10-20 |
塩野義製薬株式会社 |
インテグラーゼ阻害活性を有するピリドン誘導体
|
|
WO2011130740A2
(en)
|
2010-04-16 |
2011-10-20 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Pyridylthiazole-based ureas as inhibitors of rho associated protein kinase (rock) and methods of use
|
|
US8685969B2
(en)
*
|
2010-06-16 |
2014-04-01 |
Bristol-Myers Squibb Company |
Carboline carboxamide compounds useful as kinase inhibitors
|
|
EP2630144B1
(en)
*
|
2010-10-19 |
2016-09-07 |
Boehringer Ingelheim International GmbH |
Rho kinase inhibitors
|
|
US8703953B2
(en)
|
2012-03-09 |
2014-04-22 |
Bristol-Myers Squibb Company |
Aryl ether-base kinase inhibitors
|
|
DK2822555T3
(en)
*
|
2012-03-09 |
2018-02-05 |
Lexicon Pharmaceuticals Inc |
Inhibition of adapter-associated kinase 1 for the treatment of pain
|
|
US9914740B2
(en)
|
2013-07-02 |
2018-03-13 |
Bristol-Myers Squibb Company |
Tricyclic pyrido-carboxamide derivatives as rock inhibitors
|
|
EP3016950B1
(en)
|
2013-07-02 |
2017-06-07 |
Bristol-Myers Squibb Company |
Tricyclic pyrido-carboxamide derivatives as rock inhibitors
|