JP2016506968A - 胎盤由来のナチュラルキラー細胞 - Google Patents

胎盤由来のナチュラルキラー細胞 Download PDF

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JP2016506968A
JP2016506968A JP2015556222A JP2015556222A JP2016506968A JP 2016506968 A JP2016506968 A JP 2016506968A JP 2015556222 A JP2015556222 A JP 2015556222A JP 2015556222 A JP2015556222 A JP 2015556222A JP 2016506968 A JP2016506968 A JP 2016506968A
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cells
natural killer
placental
cell
killer cells
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JP2016506968A5 (enExample
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ズハング キアオクイ
ズハング キアオクイ
ジェイ．ハリリ ロバート
ジェイ．ハリリ ロバート
ボスキナリアン‐ベルセ バネッサ
ボスキナリアン‐ベルセ バネッサ
カング リン
カング リン
ロウ エリク
ロウ エリク
アボット スチュアート
アボット スチュアート
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アントフロゲネシス コーポレーション
アントフロゲネシス コーポレーション
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Publication of JP2016506968A publication Critical patent/JP2016506968A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22—Immunosuppressive or immunotolerising
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/418—Antigens related to induction of tolerance to non-self
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/05—Adjuvants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2015556222A 2013-02-05 2014-02-04 胎盤由来のナチュラルキラー細胞 Pending JP2016506968A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361761176P 2013-02-05 2013-02-05
US61/761,176 2013-02-05
US201361780115P 2013-03-13 2013-03-13
US61/780,115 2013-03-13
PCT/US2014/014632 WO2014123879A1 (en) 2013-02-05 2014-02-04 Natural killer cells from placenta

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018189593A Division JP2019048809A (ja) 2013-02-05 2018-10-05 胎盤由来のナチュラルキラー細胞

Publications (2)

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JP2016506968A true JP2016506968A (ja) 2016-03-07
JP2016506968A5 JP2016506968A5 (enExample) 2017-06-29

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JP2015556222A Pending JP2016506968A (ja) 2013-02-05 2014-02-04 胎盤由来のナチュラルキラー細胞
JP2018189593A Pending JP2019048809A (ja) 2013-02-05 2018-10-05 胎盤由来のナチュラルキラー細胞
JP2020129197A Withdrawn JP2020196724A (ja) 2013-02-05 2020-07-30 胎盤由来のナチュラルキラー細胞
JP2022104464A Pending JP2022130600A (ja) 2013-02-05 2022-06-29 胎盤由来のナチュラルキラー細胞

Family Applications After (3)

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JP2018189593A Pending JP2019048809A (ja) 2013-02-05 2018-10-05 胎盤由来のナチュラルキラー細胞
JP2020129197A Withdrawn JP2020196724A (ja) 2013-02-05 2020-07-30 胎盤由来のナチュラルキラー細胞
JP2022104464A Pending JP2022130600A (ja) 2013-02-05 2022-06-29 胎盤由来のナチュラルキラー細胞

Country Status (7)

Country Link
US (1) US9763983B2 (enExample)
EP (2) EP2953635A4 (enExample)
JP (4) JP2016506968A (enExample)
CN (3) CN115137753A (enExample)
AU (4) AU2014215458A1 (enExample)
HK (1) HK1218515A1 (enExample)
WO (1) WO2014123879A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015132415A1 (en) * 2014-03-07 2015-09-11 Emercell Sas Pooled nk cells from ombilical cord blood and their uses for the treatment of cancer and chronic infectious disease
CN110913870A (zh) * 2016-12-30 2020-03-24 细胞结构公司 遗传修饰的自然杀伤细胞
CN111601616A (zh) * 2017-10-24 2020-08-28 美真达治疗公司 用于耗尽cd117+细胞的组合物和方法
EP3746095A4 (en) * 2018-02-01 2021-04-21 Nkmax Co., Ltd. Method of producing natural killer cells and composition for treating cancer
BR112021015414A2 (pt) 2019-03-15 2021-10-05 Nippon Steel Corporation Trilho
CN112029721A (zh) * 2020-09-09 2020-12-04 广东昭泰体内生物医药科技有限公司 一种活性增强型nk细胞的制备方法
US20240287458A1 (en) * 2021-06-30 2024-08-29 Regrow Biosciences Private Limited Method of obtaining hsc population, t cell population and nk cell population and compositions thereof
CN113804661B (zh) * 2021-08-12 2024-08-27 深圳市锦欣医疗科技创新中心有限公司 一种评估子宫内膜容受性的试剂盒及方法
WO2025050133A1 (en) * 2023-09-01 2025-03-06 Northeastern University Isolation and expansion of natural killer cells using fluorescence-activated droplet sorting

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JP2010518096A (ja) * 2007-02-12 2010-05-27 アンスロジェネシス コーポレーション 胎盤幹細胞を使用した炎症性疾患の治療
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