JP2016073298A5 - - Google Patents
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- JP2016073298A5 JP2016073298A5 JP2015230724A JP2015230724A JP2016073298A5 JP 2016073298 A5 JP2016073298 A5 JP 2016073298A5 JP 2015230724 A JP2015230724 A JP 2015230724A JP 2015230724 A JP2015230724 A JP 2015230724A JP 2016073298 A5 JP2016073298 A5 JP 2016073298A5
- Authority
- JP
- Japan
- Prior art keywords
- reverse transcriptase
- mutations
- activity
- mutation
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 102100034343 Integrase Human genes 0.000 claims 20
- 108010092799 RNA-directed DNA polymerase Proteins 0.000 claims 20
- 230000035772 mutation Effects 0.000 claims 15
- 230000000694 effects Effects 0.000 claims 7
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- 241000713869 Moloney murine leukemia virus Species 0.000 claims 2
- 102220473257 Crossover junction endonuclease EME1_I49V_mutation Human genes 0.000 claims 1
- 102220562954 Cytochrome c oxidase subunit 7C, mitochondrial_M39V_mutation Human genes 0.000 claims 1
- 239000002299 complementary DNA Substances 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 102220266397 rs1555186808 Human genes 0.000 claims 1
- 102200163844 rs17127898 Human genes 0.000 claims 1
- 102220253369 rs201879717 Human genes 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0806562.5 | 2008-04-10 | ||
| GBGB0806562.5A GB0806562D0 (en) | 2008-04-10 | 2008-04-10 | Production of nucleic acid |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014059605A Division JP2014158473A (ja) | 2008-04-10 | 2014-03-24 | 核酸の生成 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091035A Division JP6236563B2 (ja) | 2008-04-10 | 2017-05-01 | 核酸の生成 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016073298A JP2016073298A (ja) | 2016-05-12 |
| JP2016073298A5 true JP2016073298A5 (enExample) | 2016-08-12 |
| JP6140792B2 JP6140792B2 (ja) | 2017-05-31 |
Family
ID=39433452
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503454A Active JP5642662B2 (ja) | 2008-04-10 | 2009-04-09 | 核酸の生成 |
| JP2014059605A Pending JP2014158473A (ja) | 2008-04-10 | 2014-03-24 | 核酸の生成 |
| JP2015230724A Active JP6140792B2 (ja) | 2008-04-10 | 2015-11-26 | 核酸の生成 |
| JP2017091035A Active JP6236563B2 (ja) | 2008-04-10 | 2017-05-01 | 核酸の生成 |
| JP2017208710A Active JP6473795B2 (ja) | 2008-04-10 | 2017-10-30 | 核酸の生成 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503454A Active JP5642662B2 (ja) | 2008-04-10 | 2009-04-09 | 核酸の生成 |
| JP2014059605A Pending JP2014158473A (ja) | 2008-04-10 | 2014-03-24 | 核酸の生成 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017091035A Active JP6236563B2 (ja) | 2008-04-10 | 2017-05-01 | 核酸の生成 |
| JP2017208710A Active JP6473795B2 (ja) | 2008-04-10 | 2017-10-30 | 核酸の生成 |
Country Status (14)
| Country | Link |
|---|---|
| US (5) | US8835148B2 (enExample) |
| EP (4) | EP3098308B1 (enExample) |
| JP (5) | JP5642662B2 (enExample) |
| KR (4) | KR102082768B1 (enExample) |
| CN (2) | CN107058258A (enExample) |
| AU (1) | AU2009235368B2 (enExample) |
| CA (1) | CA2721117A1 (enExample) |
| ES (1) | ES2647272T3 (enExample) |
| GB (1) | GB0806562D0 (enExample) |
| IL (2) | IL208578A (enExample) |
| NZ (1) | NZ588468A (enExample) |
| PL (1) | PL2281035T3 (enExample) |
| SG (1) | SG10201503327QA (enExample) |
| WO (1) | WO2009125006A2 (enExample) |
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| WO2003025132A2 (en) | 2001-09-14 | 2003-03-27 | Invitrogen Corporation | Dna polymerases and mutants thereof |
| GB0127564D0 (en) | 2001-11-16 | 2002-01-09 | Medical Res Council | Emulsion compositions |
| GB2388031B (en) | 2002-04-30 | 2005-07-27 | Abbott Lab | A lancet removal tool |
| KR101051245B1 (ko) * | 2002-09-06 | 2011-07-21 | 이소제니카 리미티드 | 시험관내 펩타이드 발현 라이브러리 |
| GB0221053D0 (en) | 2002-09-11 | 2002-10-23 | Medical Res Council | Single-molecule in vitro evolution |
| WO2005049787A2 (en) * | 2003-11-24 | 2005-06-02 | Yeda Research And Development Co.Ltd. | Compositions and methods for in vitro sorting of molecular and cellular libraries |
| WO2005071072A1 (en) | 2004-01-13 | 2005-08-04 | The Institute Of Biophysics Chinese Academy Of Sciences | The recombinant murine leukemia virus reverse transcriptase, the gene encoding it and the method for expressing it |
| US7595179B2 (en) | 2004-04-19 | 2009-09-29 | Applied Biosystems, Llc | Recombinant reverse transcriptases |
| WO2006051552A2 (en) | 2004-11-15 | 2006-05-18 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Directed evolution and selection using in vitro compartmentalization |
| JPWO2007011045A1 (ja) * | 2005-07-20 | 2009-02-05 | 株式会社クラレ | パージング剤 |
| WO2007022045A2 (en) * | 2005-08-10 | 2007-02-22 | Stratagene California | Mutant reverse transcriptase and methods of use |
| DK2074211T3 (da) | 2006-09-06 | 2013-06-17 | Medical Res Council | DNA polymeraser til inkorporation af farvestof-mærkede nukleotid-analoger |
| GB0806562D0 (en) * | 2008-04-10 | 2008-05-14 | Fermentas Uab | Production of nucleic acid |
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