JP2011087580A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011087580A5 JP2011087580A5 JP2010248015A JP2010248015A JP2011087580A5 JP 2011087580 A5 JP2011087580 A5 JP 2011087580A5 JP 2010248015 A JP2010248015 A JP 2010248015A JP 2010248015 A JP2010248015 A JP 2010248015A JP 2011087580 A5 JP2011087580 A5 JP 2011087580A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- seq
- vector
- amino acid
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000018102 proteins Nutrition 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 3
- 241000588724 Escherichia coli Species 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 102000008300 Mutant Proteins Human genes 0.000 claims 1
- 108010021466 Mutant Proteins Proteins 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39612602P | 2002-07-17 | 2002-07-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004520607A Division JP4726483B2 (ja) | 2002-07-17 | 2003-07-14 | 分子抗原アレイ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011087580A JP2011087580A (ja) | 2011-05-06 |
| JP2011087580A5 true JP2011087580A5 (enExample) | 2012-02-16 |
Family
ID=30115977
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004520607A Expired - Fee Related JP4726483B2 (ja) | 2002-07-17 | 2003-07-14 | 分子抗原アレイ |
| JP2009267660A Pending JP2010075196A (ja) | 2002-07-17 | 2009-11-25 | 分子抗原アレイ |
| JP2010248015A Pending JP2011087580A (ja) | 2002-07-17 | 2010-11-05 | 分子抗原アレイ |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004520607A Expired - Fee Related JP4726483B2 (ja) | 2002-07-17 | 2003-07-14 | 分子抗原アレイ |
| JP2009267660A Pending JP2010075196A (ja) | 2002-07-17 | 2009-11-25 | 分子抗原アレイ |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7138252B2 (enExample) |
| EP (2) | EP2351770A1 (enExample) |
| JP (3) | JP4726483B2 (enExample) |
| CN (2) | CN1668637B (enExample) |
| AT (1) | ATE542828T1 (enExample) |
| AU (1) | AU2003246690B2 (enExample) |
| BR (1) | BR0312935A (enExample) |
| CA (1) | CA2489410C (enExample) |
| IL (1) | IL165605A0 (enExample) |
| MX (1) | MXPA05000277A (enExample) |
| NZ (1) | NZ538083A (enExample) |
| RU (2) | RU2324704C2 (enExample) |
| WO (1) | WO2004007538A2 (enExample) |
| ZA (1) | ZA200410046B (enExample) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2407897A1 (en) * | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
| US7128911B2 (en) | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
| US7094409B2 (en) * | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
| US7320793B2 (en) * | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
| DE60234375D1 (de) | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| CA2488856A1 (en) * | 2002-06-20 | 2003-12-31 | Cytos Biotechnology Ag | Packaged virus-like particles for use as adjuvants: method of preparation and use |
| EP2351770A1 (en) * | 2002-07-17 | 2011-08-03 | Cytos Biotechnology AG | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
| EP1523334A2 (en) | 2002-07-18 | 2005-04-20 | Cytos Biotechnology AG | Hapten-carrier conjugates and uses thereof |
| ATE506964T1 (de) * | 2002-07-19 | 2011-05-15 | Cytos Biotechnology Ag | Impfstoffzusammensetzungen enthaltende amyloid beta 1-6 antigenarrays |
| EP1605973B1 (en) | 2003-03-26 | 2012-09-26 | Cytos Biotechnology AG | Packaging of immunostimulatory oligonucleotides into virus-like particles: methods of preparation and uses |
| US7537767B2 (en) | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| AU2005281743A1 (en) * | 2004-08-04 | 2006-03-16 | Cytos Biotechnology Ag | Carrier conjugates of GnRH-peptides |
| AU2005286475A1 (en) * | 2004-09-21 | 2006-03-30 | Cytos Biotechnology Ag | Virus-like particles comprising a fusion protein of the coat protein of AP205 and an antigenic polypeptide |
| US7959928B2 (en) * | 2004-10-05 | 2011-06-14 | Cytos Biotechnology Ag | VLP-antigen conjugates and their uses as vaccines |
| AU2005298689A1 (en) | 2004-10-25 | 2006-05-04 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
| WO2006045849A1 (en) * | 2004-10-29 | 2006-05-04 | Cytos Biotechnology Ag | T-cadherin antigen arrays and uses thereof |
| GB0424563D0 (en) | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
| EP1830875A2 (en) * | 2004-12-13 | 2007-09-12 | Cytos Biotechnology AG | Il-15 antigen arrays and uses thereof |
| US7767212B2 (en) * | 2005-03-18 | 2010-08-03 | Cytos Biotechnology Ag | CAT allergen conjugates and uses thereof |
| EP1746165A1 (en) | 2005-07-21 | 2007-01-24 | Cytos Biotechnology AG | Scalable fermentation process |
| ATE515566T1 (de) | 2005-05-26 | 2011-07-15 | Cytos Biotechnology Ag | Skalierbares fermentationsverfahren |
| CA2612069A1 (en) * | 2005-06-14 | 2006-12-21 | Cytos Biotechnology Ag | Antigen conjugates and uses thereof |
| EP1736538A1 (en) * | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Process for the preparative purification of virus-like-particles (VLPs) |
| ES2310062B1 (es) | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| CN101267834B (zh) | 2005-09-28 | 2013-06-05 | 赛托斯生物技术公司 | 白介素-1偶联物及其用途 |
| KR20090008176A (ko) * | 2005-12-08 | 2009-01-21 | 사우스다코타주립대학 | 감염성 프리온의 시험관 내 증식 및 검출 방법 |
| JP5484732B2 (ja) | 2005-12-14 | 2014-05-07 | サイトス バイオテクノロジー アーゲー | 過敏症の治療のための免疫賦活性核酸パッケージ粒子 |
| US7534595B2 (en) * | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
| DK2032592T3 (da) | 2006-06-12 | 2013-09-02 | Cytos Biotechnology Ag | Fremgangsmåder til pakning af oligonukleotider til virus-lignende partikler af rna-bakteriofager |
| AU2007302198A1 (en) * | 2006-09-28 | 2008-04-03 | Cytos Biotechnology Ag | Interleukin-1 muteins linked to virus-like particles to treat IL-1 associated diseases |
| WO2008100609A1 (en) | 2007-02-16 | 2008-08-21 | The Salk Institute For Biological Studies | A novel antitoxin and vaccine platform based on nodavirus vlps |
| WO2008133141A1 (ja) * | 2007-04-24 | 2008-11-06 | Toyo Boseki Kabushiki Kaisha | オスモチン組換えタンパク質およびその製造方法、並びにその利用 |
| EA023303B1 (ru) | 2007-08-15 | 2016-05-31 | Сиркейшиа Лимитед | Пептидная композиция для формирования толерантности к клещам домашней пыли и ее применение |
| US8222206B2 (en) * | 2008-03-04 | 2012-07-17 | Taiwan Advance Bio-Pharm Inc. | Method of enhancing the mobilization of hematopoietic stem cells using TAT-HOXB4H |
| AU2009240011A1 (en) * | 2008-04-22 | 2009-10-29 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| PE20110891A1 (es) | 2008-12-09 | 2011-12-23 | Pfizer Vaccines Llc | Vacuna de peptido ch3 de ige |
| WO2010122164A1 (en) | 2009-04-23 | 2010-10-28 | Cytos Biotechnology Ag | VIRUS-LIKE PARTICLES OF BACTERIOPHAGE φCB5 |
| JP2012525134A (ja) * | 2009-04-30 | 2012-10-22 | サイトス バイオテクノロジー アーゲー | インフルエンザ赤血球凝集素の組成物とその使用 |
| PE20120817A1 (es) | 2009-07-30 | 2012-07-07 | Pfizer Vaccines Llc | Peptidos tau antigenicos y usos de los mismos |
| ES2670576T3 (es) | 2009-09-03 | 2018-05-31 | Pfizer Vaccines Llc | Vacuna de PCSK9 |
| WO2011097266A1 (en) * | 2010-02-02 | 2011-08-11 | Amano Enzyme Usa, Ltd. | Use of proteases for gluten intolerance |
| CA2800774A1 (en) | 2010-06-07 | 2011-12-15 | Pfizer Vaccines Llc | Ige ch3 peptide vaccine |
| EP2680883B1 (en) | 2011-03-02 | 2018-09-05 | Pfizer Inc | Pcsk9 vaccine |
| MX2014001142A (es) | 2011-07-29 | 2014-02-27 | Selecta Biosciences Inc | Nanoportadores sinteticos que generan respuestas inmunitarias humorales y de linfocitos t citotoxicos (ctl). |
| WO2013092720A1 (en) | 2011-12-22 | 2013-06-27 | F. Hoffmann-La Roche Ag | Full length antibody display system for eukaryotic cells and its use |
| SG10201606970UA (en) | 2012-02-23 | 2016-10-28 | Juno Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| US12218609B2 (en) * | 2012-05-11 | 2025-02-04 | The Regents Of The University Of California | Virus-based piezoelectric energy generation |
| DE102013105144A1 (de) * | 2013-05-17 | 2014-11-20 | Arno Thaller | Pharmazeutisches Kombinationspräparat mit einem anti-idiotypischen Antikörperfragment |
| US10195257B2 (en) | 2013-07-28 | 2019-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response |
| WO2015123291A1 (en) | 2014-02-11 | 2015-08-20 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Pcsk9 vaccine and methods of using the same |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10526376B2 (en) | 2015-01-15 | 2020-01-07 | University Of Copenhagen | Virus-like particle with efficient epitope display |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| MX2018002926A (es) * | 2015-09-08 | 2019-01-30 | Univ Zuerich | Composiciones contra alergia a los gatos. |
| EP3141600A1 (en) | 2015-09-11 | 2017-03-15 | Institut National de la Recherche Agronomique | Nepovirus coat protein fusion polypeptides and their use |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
| RU2021134624A (ru) | 2015-10-22 | 2022-03-15 | Джуно Терапьютикс Гмбх | Способы, наборы, средства и устройства для трансдукции |
| DK3368068T3 (da) | 2015-10-30 | 2021-02-22 | Univ Copenhagen | Viruslignende partikler med effektiv epitopdisplay |
| CA3035443A1 (en) | 2016-09-02 | 2018-03-08 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| ES3038614T3 (en) | 2017-04-27 | 2025-10-14 | Juno Therapeutics Inc | Oligomeric particle reagents and methods of use thereof |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| WO2019160866A2 (en) | 2018-02-13 | 2019-08-22 | Checkmate Pharmaceuticals, Inc. | Compositions and methods for tumor immunotherapy |
| WO2019197965A1 (en) | 2018-04-09 | 2019-10-17 | Checkmate Pharmaceuticals | Packaging oligonucleotides into virus-like particles |
| CN112105733B (zh) | 2018-04-19 | 2024-10-29 | 查美特制药公司 | 合成rig-i样受体激动剂 |
| MX2021001523A (es) | 2018-08-09 | 2021-05-27 | Juno Therapeutics Inc | Procesos para generar células modificadas y composiciones de las mismas. |
| WO2020089343A1 (en) | 2018-10-31 | 2020-05-07 | Juno Therapeutics Gmbh | Methods for selection and stimulation of cells and apparatus for same |
| EP3921332A2 (en) * | 2019-02-08 | 2021-12-15 | The USA, as represented by The Secretary, Department of Health and Human Services | Nanoparticle-based influenza virus vaccines and uses thereof |
| US12433904B2 (en) | 2019-04-17 | 2025-10-07 | Compass Pathfinder Limited | Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin |
| US12161710B2 (en) | 2019-07-24 | 2024-12-10 | Unm Rainforest Innovations | Malaria immunogen and methods for using same |
| JP7707161B2 (ja) | 2019-10-23 | 2025-07-14 | チェックメイト ファーマシューティカルズ, インコーポレイテッド | 合成rig-i様受容体アゴニスト |
| US20230063876A1 (en) * | 2020-03-02 | 2023-03-02 | Unm Rainforest Innovations | Virus-Like Particle Vaccines for Opioid Drugs |
| EP4141110A4 (en) | 2020-04-24 | 2025-04-09 | Sf Biotech Laboratuvar Danismanlik Anonim Sirketi | Method for producing particles of bacteriophages of the genus levivirus |
| US12240813B2 (en) | 2020-05-19 | 2025-03-04 | Cybin Irl Limited | Deuterated tryptamine derivatives and methods of use |
| CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
| CN114634578B (zh) * | 2020-12-15 | 2024-04-02 | 榕森生物科技(北京)有限公司 | 针对新型冠状病毒感染的疫苗组合物 |
| CN114632148B (zh) * | 2020-12-15 | 2024-08-09 | 榕森生物科技(北京)有限公司 | 病原样抗原疫苗及其制备方法 |
| CN112480245B (zh) * | 2020-12-19 | 2023-08-18 | 上海佰君生物科技有限公司 | 一种疏水性环状肽配基纯化人免疫球蛋白g的应用 |
| US20240189407A1 (en) | 2021-04-12 | 2024-06-13 | Saiba AG | Modified virus-like particles of bacteriophage ap205 |
| WO2022229817A1 (en) | 2021-04-28 | 2022-11-03 | Bavarian Nordic A/S | Vaccines comprising virus-like particles displaying sars-cov-2 antigens and methods of use |
| US12121574B2 (en) | 2021-09-28 | 2024-10-22 | Unm Rainforest Innovations | Malaria immunogen and methods for using same |
| JP2025529128A (ja) | 2022-08-31 | 2025-09-04 | ユーエヌエム レインフォレスト イノベーションズ | カスパーゼ活性化及び動員ドメイン(asc)を有するアポトーシス関連スペック様タンパク質を標的化する組成物及び使用方法 |
| WO2024068265A2 (en) | 2022-09-30 | 2024-04-04 | Bavarian Nordic A/S | Virus-like particles displaying sars-cov-2 antigens as booster vaccines and uses thereof |
| CN115819623A (zh) * | 2022-12-12 | 2023-03-21 | 长春百克生物科技股份公司 | 一种重组病毒样颗粒疫苗组合物的制备及应用 |
| WO2025000310A1 (zh) * | 2023-06-29 | 2025-01-02 | 深圳赫兹生命科学技术有限公司 | 去势ap205病毒样颗粒亚单位疫苗的制备方法 |
| CN116987700B (zh) * | 2023-07-13 | 2024-02-20 | 杭州赛基生物科技有限公司 | 一种人白细胞介素-5重组蛋白及其制备方法 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US394A (en) * | 1837-09-21 | Mode of regulating the temperature of inkiwg-rollers and ink used | ||
| US5334A (en) * | 1847-10-16 | Improvement in cutter-heads for plan ing-machines | ||
| US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| CA1319101C (en) | 1986-09-03 | 1993-06-15 | Marta Iris Sabara | Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules |
| US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
| KR920002165B1 (ko) | 1986-09-22 | 1992-03-19 | 에모리 유니버어시티 | 개선된 백신 및 제조방법 |
| US5143726A (en) | 1986-12-09 | 1992-09-01 | The Scripps Research Institute | T cell epitopes of the hepatitis B virus nucleocapsid protein |
| US4918166A (en) | 1987-04-10 | 1990-04-17 | Oxford Gene Systems Limited | Particulate hybrid HIV antigens |
| GB8903313D0 (en) | 1989-02-14 | 1989-04-05 | Wellcome Found | Conjugates |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| EP0425082B1 (en) | 1989-09-04 | 1995-04-26 | Evans Medical Limited | Bordetella vaccines |
| JP3068180B2 (ja) | 1990-01-12 | 2000-07-24 | アブジェニックス インコーポレイテッド | 異種抗体の生成 |
| US5334394A (en) | 1990-06-22 | 1994-08-02 | The Regents Of The University Of California | Human immunodeficiency virus decoy |
| US5178882A (en) | 1990-06-22 | 1993-01-12 | The Regents Of The University Of California | Viral decoy vaccine |
| SE9003978D0 (sv) | 1990-12-13 | 1990-12-13 | Henrik Garoff | Dna expressionssystem baserade paa ett virus replikon |
| AU9052091A (en) | 1990-12-20 | 1992-07-22 | Smithkline Beecham Biologicals (Sa) | Vaccines based on hepatitis b surface antigen |
| GB9114003D0 (en) | 1991-06-28 | 1991-08-14 | Mastico Robert A | Chimaeric protein |
| US6004763A (en) | 1992-09-11 | 1999-12-21 | Institut Pasteur | Antigen-carrying microparticles and their use in the induction of humoral or cellular responses |
| FR2695563B1 (fr) | 1992-09-11 | 1994-12-02 | Pasteur Institut | Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires. |
| DE69418699T2 (de) | 1993-01-11 | 1999-09-30 | Dana-Farber Cancer Institute, Boston | Induktion der antworten zytotoxischer t-lymphozyten |
| WO1994017813A1 (en) | 1993-02-08 | 1994-08-18 | Paravax, Inc. | Defective sindbis virus vectors that express toxoplasma gondii p30 antigens |
| US6015686A (en) | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| AT402898B (de) | 1994-08-08 | 1997-09-25 | Int Centre Genetic Eng & Bio | Molekulares präsentiersystem |
| CN1185811A (zh) | 1995-03-31 | 1998-06-24 | H·沃尔夫 | 依赖于逆转录病毒样颗粒的抗原呈递系统 |
| US5792462A (en) | 1995-05-23 | 1998-08-11 | University Of North Carolina At Chapel Hill | Alphavirus RNA replicon systems |
| CA2245497C (en) | 1996-03-01 | 2009-02-24 | Novartis Ag | Peptide immunogens for vaccination against and treatment of allergy |
| US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
| GB9621091D0 (en) | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| JP5132851B2 (ja) | 1997-08-05 | 2013-01-30 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー(ヴェーイーベー・ヴェーゼットウェー) | 新しい免疫防御性インフルエンザ抗原及びそのワクチン接種への使用 |
| US6169175B1 (en) | 1997-08-06 | 2001-01-02 | Centers For Disease Control And Prevention | Preparation and use of recombinant influenza A virus M2 construct vaccines |
| US6054312A (en) | 1997-08-29 | 2000-04-25 | Selective Genetics, Inc. | Receptor-mediated gene delivery using bacteriophage vectors |
| CA2320488C (en) | 1998-02-12 | 2007-03-06 | Immune Complex, Corporation | Strategically modified hepatitis b core proteins and their derivatives |
| US5990085A (en) | 1998-05-04 | 1999-11-23 | Michigan State University | Inhibin-HBc fusion protein |
| TWI227241B (en) | 1998-06-20 | 2005-02-01 | United Biomedical Inc | IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate |
| ATE314095T1 (de) | 1998-10-21 | 2006-01-15 | Us Health | Virusähnliche partikel zur induktion von autoantikörpern |
| US6380364B1 (en) | 1998-11-23 | 2002-04-30 | Loyola University Of Chicago | Chimeric biotin-binding papillomavirus protein |
| AU768807B2 (en) | 1998-11-30 | 2004-01-08 | Cytos Biotechnology Ag | Ordered molecular presentation of antigens, method of preparation and use |
| HU229222B1 (en) | 1998-12-04 | 2013-09-30 | Biogen Idec Ma Inc Cambridge | Hbv core antigen particles with multiple immunogenic components attached via peptide ligands |
| JP2002537403A (ja) | 1999-02-25 | 2002-11-05 | スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム | IgEのC−イプシロン−3またはC−イプシロン−4ドメイン由来のエピトープまたはミモトープ、その拮抗薬、及びそれらの治療的使用 |
| US6613742B1 (en) | 1999-04-07 | 2003-09-02 | Thomas Jefferson University | Chemokine-derived synthetic peptides |
| DK1259251T3 (da) | 2000-02-21 | 2006-03-06 | Pharmexa As | Hidtil ukendt fremgangsmåde til nedregulering af amyloid |
| CA2407897A1 (en) | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
| US7094409B2 (en) | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
| US7320793B2 (en) | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
| US7128911B2 (en) * | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
| DE60234375D1 (de) | 2001-09-14 | 2009-12-24 | Cytos Biotechnology Ag | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| WO2003024431A1 (en) | 2001-09-21 | 2003-03-27 | Coloplast A/S | Device for the administration of an active agent to the human skin |
| US7115266B2 (en) * | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| ES2316628T3 (es) * | 2001-11-07 | 2009-04-16 | Cytos Biotechnology Ag | Disposicion ordenada de antigenos que comprende rankl para el tratamiento de enfermedades oseas. |
| JP3787697B2 (ja) | 2002-01-08 | 2006-06-21 | 独立行政法人理化学研究所 | 重イオンビーム照射によるキメラ植物の作出方法 |
| EP2351770A1 (en) * | 2002-07-17 | 2011-08-03 | Cytos Biotechnology AG | Molecular antigen arrays using a virus like particle derived from the ap205 coat protein |
| EP1523334A2 (en) * | 2002-07-18 | 2005-04-20 | Cytos Biotechnology AG | Hapten-carrier conjugates and uses thereof |
| ATE506964T1 (de) * | 2002-07-19 | 2011-05-15 | Cytos Biotechnology Ag | Impfstoffzusammensetzungen enthaltende amyloid beta 1-6 antigenarrays |
| EP1605973B1 (en) * | 2003-03-26 | 2012-09-26 | Cytos Biotechnology AG | Packaging of immunostimulatory oligonucleotides into virus-like particles: methods of preparation and uses |
| US7537767B2 (en) * | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| EP1656332B1 (en) | 2003-07-25 | 2017-03-15 | Waste 2 Green, LLC | Method and system for treating waste matter from animals containing urea |
| AU2005298689A1 (en) * | 2004-10-25 | 2006-05-04 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
| US7767212B2 (en) * | 2005-03-18 | 2010-08-03 | Cytos Biotechnology Ag | CAT allergen conjugates and uses thereof |
-
2003
- 2003-07-14 EP EP10011277A patent/EP2351770A1/en not_active Withdrawn
- 2003-07-14 CN CN038168626A patent/CN1668637B/zh not_active Expired - Fee Related
- 2003-07-14 JP JP2004520607A patent/JP4726483B2/ja not_active Expired - Fee Related
- 2003-07-14 CA CA2489410A patent/CA2489410C/en not_active Expired - Fee Related
- 2003-07-14 US US10/617,876 patent/US7138252B2/en not_active Expired - Fee Related
- 2003-07-14 WO PCT/EP2003/007572 patent/WO2004007538A2/en not_active Ceased
- 2003-07-14 AU AU2003246690A patent/AU2003246690B2/en not_active Ceased
- 2003-07-14 RU RU2005104235/13A patent/RU2324704C2/ru not_active IP Right Cessation
- 2003-07-14 MX MXPA05000277A patent/MXPA05000277A/es active IP Right Grant
- 2003-07-14 BR BR0312935-7A patent/BR0312935A/pt not_active IP Right Cessation
- 2003-07-14 NZ NZ538083A patent/NZ538083A/en not_active IP Right Cessation
- 2003-07-14 CN CN2010101587965A patent/CN102061288A/zh active Pending
- 2003-07-14 EP EP03763829A patent/EP1532167B1/en not_active Expired - Lifetime
- 2003-07-14 AT AT03763829T patent/ATE542828T1/de active
-
2004
- 2004-12-07 IL IL16560504A patent/IL165605A0/xx unknown
- 2004-12-13 ZA ZA200410046A patent/ZA200410046B/en unknown
-
2006
- 2006-11-20 US US11/601,687 patent/US7494656B2/en not_active Expired - Fee Related
-
2007
- 2007-12-03 RU RU2007144895/13A patent/RU2007144895A/ru not_active Application Discontinuation
-
2008
- 2008-12-22 US US12/341,763 patent/US20100092508A1/en not_active Abandoned
-
2009
- 2009-11-25 JP JP2009267660A patent/JP2010075196A/ja active Pending
-
2010
- 2010-11-05 JP JP2010248015A patent/JP2011087580A/ja active Pending