JP2007502123A5 - - Google Patents

Info

Publication number

JP2007502123A5

JP2007502123A5 JP2006523447A JP2006523447A JP2007502123A5 JP 2007502123 A5 JP2007502123 A5 JP 2007502123A5 JP 2006523447 A JP2006523447 A JP 2006523447A JP 2006523447 A JP2006523447 A JP 2006523447A JP 2007502123 A5 JP2007502123 A5 JP 2007502123A5

Authority

JP

Japan

Prior art keywords

seq

sequence number

polypeptide

amino acid

sequence

Prior art date

2004-08-11

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 229920001184 polypeptide Polymers 0.000 claims 52
• 102000004196 processed proteins & peptides Human genes 0.000 claims 52
• 108090000765 processed proteins & peptides Proteins 0.000 claims 52
• 125000003275 alpha amino acid group Chemical group 0.000 claims 19
• 108010013164 halohydrin dehalogenase Proteins 0.000 claims 14
• 235000001014 amino acid Nutrition 0.000 claims 5
• 230000000694 effects Effects 0.000 claims 5
• LOQFROBMBSKWQY-ZCFIWIBFSA-N ethyl (3r)-4-cyano-3-hydroxybutanoate Chemical compound CCOC(=O)C[C@H](O)CC#N LOQFROBMBSKWQY-ZCFIWIBFSA-N 0.000 claims 5
• 102000040430 polynucleotide Human genes 0.000 claims 5
• 108091033319 polynucleotide Proteins 0.000 claims 5
• 239000002157 polynucleotide Substances 0.000 claims 5
• 241000589159 Agrobacterium sp. Species 0.000 claims 4
• ZAJNMXDBJKCCAT-YFKPBYRVSA-N ethyl (3s)-4-chloro-3-hydroxybutanoate Chemical compound CCOC(=O)C[C@H](O)CCl ZAJNMXDBJKCCAT-YFKPBYRVSA-N 0.000 claims 4
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 108091028043 Nucleic acid sequence Proteins 0.000 claims 3
• 238000000034 method Methods 0.000 claims 3
• 150000007523 nucleic acids Chemical group 0.000 claims 3
• 102220607116 Copper homeostasis protein cutC homolog_F82Y_mutation Human genes 0.000 claims 2
• AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 2
• 125000000539 amino acid group Chemical group 0.000 claims 2
• 239000013604 expression vector Substances 0.000 claims 2
• 229960000310 isoleucine Drugs 0.000 claims 2
• AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 claims 2
• 102220511215 APC membrane recruitment protein 1_R20K_mutation Human genes 0.000 claims 1
• 102220470105 Amidophosphoribosyltransferase_Q37H_mutation Human genes 0.000 claims 1
• 102220534732 Angiopoietin-related protein 4_E40D_mutation Human genes 0.000 claims 1
• 108020004705 Codon Proteins 0.000 claims 1
• WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
• 102220619692 Hemoglobin subunit alpha_F44L_mutation Human genes 0.000 claims 1
• 102220565920 Histatin-3_K36N_mutation Human genes 0.000 claims 1
• 102220466726 Histone H4 transcription factor_S78C_mutation Human genes 0.000 claims 1
• KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims 1
• 239000004472 Lysine Substances 0.000 claims 1
• 102220538480 Methionine-tRNA ligase, cytoplasmic_H26Q_mutation Human genes 0.000 claims 1
• 102220617931 Phenylalanine-4-hydroxylase_E56D_mutation Human genes 0.000 claims 1
• 102220489342 Phosphatidylinositol transfer protein alpha isoform_E85Q_mutation Human genes 0.000 claims 1
• ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims 1
• 102220547916 Serine protease HTRA2, mitochondrial_A93D_mutation Human genes 0.000 claims 1
• 102220504163 Testis-specific XK-related protein, Y-linked 2_H31L_mutation Human genes 0.000 claims 1
• 102220370333 c.286G>A Human genes 0.000 claims 1
• 102220346328 c.82G>T Human genes 0.000 claims 1
• 230000000295 complement effect Effects 0.000 claims 1
• 235000013922 glutamic acid Nutrition 0.000 claims 1
• 239000004220 glutamic acid Substances 0.000 claims 1
• 102220074162 rs113134544 Human genes 0.000 claims 1
• 102200139755 rs11575292 Human genes 0.000 claims 1
• 102200005925 rs117535951 Human genes 0.000 claims 1
• 102200080104 rs121908636 Human genes 0.000 claims 1
• 102200000390 rs121917859 Human genes 0.000 claims 1
• 102220274085 rs1245499278 Human genes 0.000 claims 1
• 102220039793 rs138399473 Human genes 0.000 claims 1
• 102220068533 rs148345688 Human genes 0.000 claims 1
• 102220262974 rs1554304971 Human genes 0.000 claims 1
• 102200050020 rs1554988032 Human genes 0.000 claims 1
• 102220266387 rs1555186687 Human genes 0.000 claims 1
• 102200079914 rs193302884 Human genes 0.000 claims 1
• 102200065445 rs193929333 Human genes 0.000 claims 1
• 102220268018 rs201210997 Human genes 0.000 claims 1
• 102220124207 rs201554429 Human genes 0.000 claims 1
• 102200118213 rs33950542 Human genes 0.000 claims 1
• 102200029950 rs35898499 Human genes 0.000 claims 1
• 102220074718 rs527452801 Human genes 0.000 claims 1
• 102200100726 rs61752874 Human genes 0.000 claims 1
• 102220057652 rs730881912 Human genes 0.000 claims 1
• 102220340474 rs778053171 Human genes 0.000 claims 1
• 102220084927 rs778740017 Human genes 0.000 claims 1
• 102220059022 rs786201869 Human genes 0.000 claims 1
• 102220000564 rs78778622 Human genes 0.000 claims 1
• 102220264742 rs864622263 Human genes 0.000 claims 1
• 102220098472 rs878853116 Human genes 0.000 claims 1
• 102220105302 rs879254423 Human genes 0.000 claims 1
• 102220105339 rs879254449 Human genes 0.000 claims 1
• 102200143454 rs886037864 Human genes 0.000 claims 1
• 102220192607 rs886057610 Human genes 0.000 claims 1
• 238000006467 substitution reaction Methods 0.000 claims 1