JP2011507515A5 - - Google Patents
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- Publication number
- JP2011507515A5 JP2011507515A5 JP2010539483A JP2010539483A JP2011507515A5 JP 2011507515 A5 JP2011507515 A5 JP 2011507515A5 JP 2010539483 A JP2010539483 A JP 2010539483A JP 2010539483 A JP2010539483 A JP 2010539483A JP 2011507515 A5 JP2011507515 A5 JP 2011507515A5
- Authority
- JP
- Japan
- Prior art keywords
- vsv
- protein
- nucleic acid
- attenuated
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000711975 Vesicular stomatitis virus Species 0.000 claims 32
- 238000000034 method Methods 0.000 claims 15
- 108091006027 G proteins Proteins 0.000 claims 14
- 102000030782 GTP binding Human genes 0.000 claims 14
- 108091000058 GTP-Binding Proteins 0.000 claims 14
- 230000002238 attenuated effect Effects 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 11
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 9
- 241000700605 Viruses Species 0.000 claims 4
- 239000013612 plasmid Substances 0.000 claims 4
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 3
- 238000004113 cell culture Methods 0.000 claims 3
- 230000002950 deficient Effects 0.000 claims 3
- 230000003612 virological effect Effects 0.000 claims 3
- 108091026890 Coding region Proteins 0.000 claims 2
- 108020004705 Codon Proteins 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 2
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 claims 2
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 claims 2
- 108700026244 Open Reading Frames Proteins 0.000 claims 2
- 102000009572 RNA Polymerase II Human genes 0.000 claims 2
- 108010009460 RNA Polymerase II Proteins 0.000 claims 2
- 239000002299 complementary DNA Substances 0.000 claims 2
- 230000001419 dependent effect Effects 0.000 claims 2
- 239000013604 expression vector Substances 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 241000701022 Cytomegalovirus Species 0.000 claims 1
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 1
- 101150082239 G gene Proteins 0.000 claims 1
- 101710085938 Matrix protein Proteins 0.000 claims 1
- 101710127721 Membrane protein Proteins 0.000 claims 1
- 101710141454 Nucleoprotein Proteins 0.000 claims 1
- 101710181008 P protein Proteins 0.000 claims 1
- 101710177166 Phosphoprotein Proteins 0.000 claims 1
- 101710137500 T7 RNA polymerase Proteins 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 238000009395 breeding Methods 0.000 claims 1
- 230000001488 breeding effect Effects 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 238000004520 electroporation Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 239000013600 plasmid vector Substances 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
Images
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1537507P | 2007-12-20 | 2007-12-20 | |
| PCT/US2008/013834 WO2009085178A1 (en) | 2007-12-20 | 2008-12-18 | Methods for packaging propagation-defective vesicular stomatitis virus vectors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011507515A JP2011507515A (ja) | 2011-03-10 |
| JP2011507515A5 true JP2011507515A5 (enExample) | 2012-02-02 |
Family
ID=40431947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539483A Pending JP2011507515A (ja) | 2007-12-20 | 2008-12-18 | 繁殖欠損水疱性口内炎ウイルスベクターをパッケージングする方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090175900A1 (enExample) |
| EP (1) | EP2225368A1 (enExample) |
| JP (1) | JP2011507515A (enExample) |
| AR (1) | AR069884A1 (enExample) |
| AU (1) | AU2008343925B2 (enExample) |
| CA (1) | CA2710356A1 (enExample) |
| CL (1) | CL2008003820A1 (enExample) |
| WO (1) | WO2009085178A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013026054A2 (en) * | 2011-08-18 | 2013-02-21 | Axella Solutions, Llc | Production of infectious rna viruses in yeast |
| EP3708176A1 (en) | 2019-03-15 | 2020-09-16 | Centre National De La Recherche Scientifique -Cnrs- | Mutant vsv ectodomain polypeptide and uses thereof |
| CN113559254B (zh) * | 2021-08-09 | 2023-02-10 | 苏州大学 | 一种狂犬病毒疫苗及其制备方法 |
| CN115725657B (zh) * | 2022-09-16 | 2024-06-04 | 中国科学院广州生物医药与健康研究院 | 一种节段化的水泡性口炎病毒载体及其制备方法和应用 |
| CN118421571A (zh) * | 2024-02-01 | 2024-08-02 | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 表达尼帕病毒囊膜糖蛋白的嵌合型vsv重组病毒及其应用 |
| CN120966775B (zh) * | 2025-10-21 | 2026-02-03 | 浙江迪福润丝生物科技股份有限公司 | 一种携带马尔堡病毒缺陷型g蛋白的无神经毒性vsv载体重组溶瘤病毒 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
| AU739597B2 (en) * | 1997-05-02 | 2001-10-18 | Uab Research Foundation, The | Attenuation of negative stranded RNA viruses by rearrangement of their genes and uses thereof |
| US6596529B1 (en) * | 1997-05-02 | 2003-07-22 | Uab Research Foundation | Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof |
| KR101020532B1 (ko) * | 2003-06-09 | 2011-03-09 | 와이어쓰 엘엘씨 | ｃＤＮＡ로부터의 비분절 네가티브 쇄 ＲＮＡ 바이러스의 회수를 위한 개선된 방법 |
-
2008
- 2008-12-16 US US12/335,763 patent/US20090175900A1/en not_active Abandoned
- 2008-12-18 EP EP08868608A patent/EP2225368A1/en not_active Withdrawn
- 2008-12-18 AU AU2008343925A patent/AU2008343925B2/en not_active Ceased
- 2008-12-18 WO PCT/US2008/013834 patent/WO2009085178A1/en not_active Ceased
- 2008-12-18 CA CA2710356A patent/CA2710356A1/en not_active Abandoned
- 2008-12-18 JP JP2010539483A patent/JP2011507515A/ja active Pending
- 2008-12-19 AR ARP080105637A patent/AR069884A1/es unknown
- 2008-12-19 CL CL2008003820A patent/CL2008003820A1/es unknown
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