ATE556141T1 - Verfahren zur herstellung eines optisch angereicherten tertiären alkohols - Google Patents
Verfahren zur herstellung eines optisch angereicherten tertiären alkoholsInfo
- Publication number
- ATE556141T1 ATE556141T1 AT06841340T AT06841340T ATE556141T1 AT E556141 T1 ATE556141 T1 AT E556141T1 AT 06841340 T AT06841340 T AT 06841340T AT 06841340 T AT06841340 T AT 06841340T AT E556141 T1 ATE556141 T1 AT E556141T1
- Authority
- AT
- Austria
- Prior art keywords
- tertiary alcohol
- producing
- optically enriched
- enriched tertiary
- formula
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000003509 tertiary alcohols Chemical class 0.000 title abstract 2
- 150000002118 epoxides Chemical class 0.000 abstract 1
- 108010013164 halohydrin dehalogenase Proteins 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
- C12P13/004—Cyanohydrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05112657 | 2005-12-21 | ||
| PCT/EP2006/069626 WO2007071599A2 (en) | 2005-12-21 | 2006-12-13 | A process for the production of an optically enriched tertiary alcohol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE556141T1 true ATE556141T1 (de) | 2012-05-15 |
Family
ID=38007081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06841340T ATE556141T1 (de) | 2005-12-21 | 2006-12-13 | Verfahren zur herstellung eines optisch angereicherten tertiären alkohols |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8198069B2 (de) |
| EP (1) | EP1966385B1 (de) |
| AT (1) | ATE556141T1 (de) |
| WO (1) | WO2007071599A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2379713A4 (de) * | 2008-12-18 | 2013-07-10 | Codexis Inc | Rekombinante halohydrin-dehalogenase-polypeptide |
| JP2011004738A (ja) * | 2009-05-28 | 2011-01-13 | Mitsubishi Rayon Co Ltd | 改良型ハロヒドリンエポキシダーゼ |
| EP3524675A1 (de) * | 2018-02-13 | 2019-08-14 | ETH Zürich | Herstellung von tertiären alkoholen, auflösung von tertiären alkoholen und stereoselektive deuteration oder tritiation durch retroaldolasen |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3026367B2 (ja) | 1991-03-04 | 2000-03-27 | 秀明 山田 | ハロヒドリンエポキシダ−ゼ遺伝子を有する組換え体プラスミドにより形質転換された微生物による３−ヒドロキシニトリル化合物の製造法 |
| EP0879890A1 (de) | 1997-05-21 | 1998-11-25 | Rijksuniversiteit te Groningen | Enantioselektive Epoxid-Hydrolasen und dafür kodierende Gene |
| EP1158054A1 (de) | 2000-05-25 | 2001-11-28 | Rijksuniversiteit te Groningen | Enzymatische Umwandlung von Epoxiden |
| AU2004266100A1 (en) | 2003-08-11 | 2005-03-03 | Codexis, Inc. | Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters |
| EP1654356A1 (de) * | 2003-08-11 | 2006-05-10 | Codexis, Inc. | Verbesserte halohydrin dehalogenases und verwandte polynukleotide |
| ATE437954T1 (de) * | 2006-03-03 | 2009-08-15 | Basf Se | Verfahren zur herstellung optisch aktiver 5- substituierter 2-oxazolidinone aus racemischen epoxiden und cyanat unter einsatz einer halohydrin-dehalogenase |
-
2006
- 2006-12-13 WO PCT/EP2006/069626 patent/WO2007071599A2/en active Application Filing
- 2006-12-13 EP EP06841340A patent/EP1966385B1/de not_active Not-in-force
- 2006-12-13 US US12/158,334 patent/US8198069B2/en not_active Expired - Fee Related
- 2006-12-13 AT AT06841340T patent/ATE556141T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| US8198069B2 (en) | 2012-06-12 |
| EP1966385A2 (de) | 2008-09-10 |
| EP1966385B1 (de) | 2012-05-02 |
| WO2007071599A2 (en) | 2007-06-28 |
| US20080299626A1 (en) | 2008-12-04 |
| WO2007071599A3 (en) | 2007-08-16 |
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