JP2011087580A5 - - Google Patents
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- JP2011087580A5 JP2011087580A5 JP2010248015A JP2010248015A JP2011087580A5 JP 2011087580 A5 JP2011087580 A5 JP 2011087580A5 JP 2010248015 A JP2010248015 A JP 2010248015A JP 2010248015 A JP2010248015 A JP 2010248015A JP 2011087580 A5 JP2011087580 A5 JP 2011087580A5
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- Japan
- Prior art keywords
- protein
- seq
- vector
- amino acid
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 235000018102 proteins Nutrition 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 3
- 241000588724 Escherichia coli Species 0.000 claims 2
- 229920001850 Nucleic acid sequence Polymers 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 102000008300 Mutant Proteins Human genes 0.000 claims 1
- 108010021466 Mutant Proteins Proteins 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 claims 1
- 125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 claims 1
Claims (1)
- (1) 少なくとも80%が配列番号:2または配列番号:4のヌクレオチド配列と同一であるヌクレオチド配列を含むベクターを提供する段階
(2) 該ベクターを大腸菌に導入する段階;
(3) 該大腸菌において該ベクターの配列を発現させる段階を含む、ウイルス様粒子を産生する方法であって、該ウイルス様粒子が以下の(a)から(c)からなる群より選択される少なくとも1つのタンパク質を含む、方法:
(a) 配列番号:1の2から131のアミノ酸配列を有するタンパク質;
(b) 配列番号:3の2から131のアミノ酸配列を有するタンパク質;および
(c) 会合してウイルス様粒子を形成し得る、(a)または(b)のタンパク質の突然変異タンパク質であって、
(i) 3つ、2つまたは1つのアミノ酸残基が付加、除去、または置換され;かつ/または
(ii) 1つまたは2つのシステイン残基が除去または置換され;かつ/または
(iii) 3つ、2つまたは1つのリジン残基が付加、除去、または置換されている突然変異タンパク質。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39612602P | 2002-07-17 | 2002-07-17 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004520607A Division JP4726483B2 (ja) | 2002-07-17 | 2003-07-14 | 分子抗原アレイ |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2011087580A JP2011087580A (ja) | 2011-05-06 |
JP2011087580A5 true JP2011087580A5 (ja) | 2012-02-16 |
Family
ID=30115977
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004520607A Expired - Fee Related JP4726483B2 (ja) | 2002-07-17 | 2003-07-14 | 分子抗原アレイ |
JP2009267660A Pending JP2010075196A (ja) | 2002-07-17 | 2009-11-25 | 分子抗原アレイ |
JP2010248015A Pending JP2011087580A (ja) | 2002-07-17 | 2010-11-05 | 分子抗原アレイ |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004520607A Expired - Fee Related JP4726483B2 (ja) | 2002-07-17 | 2003-07-14 | 分子抗原アレイ |
JP2009267660A Pending JP2010075196A (ja) | 2002-07-17 | 2009-11-25 | 分子抗原アレイ |
Country Status (15)
Country | Link |
---|---|
US (3) | US7138252B2 (ja) |
EP (2) | EP2351770A1 (ja) |
JP (3) | JP4726483B2 (ja) |
CN (2) | CN102061288A (ja) |
AT (1) | ATE542828T1 (ja) |
AU (1) | AU2003246690B2 (ja) |
BR (1) | BR0312935A (ja) |
CA (1) | CA2489410C (ja) |
HK (1) | HK1078880A1 (ja) |
IL (1) | IL165605A0 (ja) |
MX (1) | MXPA05000277A (ja) |
NZ (1) | NZ538083A (ja) |
RU (2) | RU2324704C2 (ja) |
WO (1) | WO2004007538A2 (ja) |
ZA (1) | ZA200410046B (ja) |
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JP3787697B2 (ja) | 2002-01-08 | 2006-06-21 | 独立行政法人理化学研究所 | 重イオンビーム照射によるキメラ植物の作出方法 |
MXPA05000277A (es) * | 2002-07-17 | 2005-03-31 | Cytos Biotechnology Ag | Configuraciones de antigenos moleculares de usan una particula tipo virus derivada de la proteina de recurimiento ap205. |
KR101228376B1 (ko) * | 2002-07-18 | 2013-01-31 | 사이토스 바이오테크놀로지 아게 | 합텐-캐리어 컨쥬게이트 및 그의 용도 |
WO2004016282A1 (en) * | 2002-07-19 | 2004-02-26 | Cytos Biotechnology Ag | Vaccine compositions containing amyloid beta1-6 antigen arrays |
US7537767B2 (en) * | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
EP1605972A2 (en) * | 2003-03-26 | 2005-12-21 | Cytos Biotechnology AG | Hiv-peptide-carrier-conjugates |
US7731856B2 (en) | 2003-07-25 | 2010-06-08 | Waste 2 Green, Llc | Method and system for treating waste matter from animals, urea-rich and urea-lean waste-matter products, and uses thereof |
US7572451B2 (en) * | 2004-10-25 | 2009-08-11 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
US7767212B2 (en) * | 2005-03-18 | 2010-08-03 | Cytos Biotechnology Ag | CAT allergen conjugates and uses thereof |
-
2003
- 2003-07-14 MX MXPA05000277A patent/MXPA05000277A/es active IP Right Grant
- 2003-07-14 CN CN2010101587965A patent/CN102061288A/zh active Pending
- 2003-07-14 AU AU2003246690A patent/AU2003246690B2/en not_active Ceased
- 2003-07-14 EP EP10011277A patent/EP2351770A1/en not_active Withdrawn
- 2003-07-14 JP JP2004520607A patent/JP4726483B2/ja not_active Expired - Fee Related
- 2003-07-14 AT AT03763829T patent/ATE542828T1/de active
- 2003-07-14 WO PCT/EP2003/007572 patent/WO2004007538A2/en active Application Filing
- 2003-07-14 BR BR0312935-7A patent/BR0312935A/pt not_active IP Right Cessation
- 2003-07-14 CN CN038168626A patent/CN1668637B/zh not_active Expired - Fee Related
- 2003-07-14 CA CA2489410A patent/CA2489410C/en not_active Expired - Fee Related
- 2003-07-14 EP EP03763829A patent/EP1532167B1/en not_active Expired - Lifetime
- 2003-07-14 US US10/617,876 patent/US7138252B2/en not_active Expired - Fee Related
- 2003-07-14 RU RU2005104235/13A patent/RU2324704C2/ru not_active IP Right Cessation
- 2003-07-14 NZ NZ538083A patent/NZ538083A/en not_active IP Right Cessation
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2004
- 2004-12-07 IL IL16560504A patent/IL165605A0/xx unknown
- 2004-12-13 ZA ZA200410046A patent/ZA200410046B/en unknown
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2005
- 2005-11-24 HK HK05110669.4A patent/HK1078880A1/xx not_active IP Right Cessation
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2006
- 2006-11-20 US US11/601,687 patent/US7494656B2/en not_active Expired - Fee Related
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2007
- 2007-12-03 RU RU2007144895/13A patent/RU2007144895A/ru not_active Application Discontinuation
-
2008
- 2008-12-22 US US12/341,763 patent/US20100092508A1/en not_active Abandoned
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2009
- 2009-11-25 JP JP2009267660A patent/JP2010075196A/ja active Pending
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2010
- 2010-11-05 JP JP2010248015A patent/JP2011087580A/ja active Pending
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