JP2015530370A5 - - Google Patents
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- Publication number
- JP2015530370A5 JP2015530370A5 JP2015526612A JP2015526612A JP2015530370A5 JP 2015530370 A5 JP2015530370 A5 JP 2015530370A5 JP 2015526612 A JP2015526612 A JP 2015526612A JP 2015526612 A JP2015526612 A JP 2015526612A JP 2015530370 A5 JP2015530370 A5 JP 2015530370A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- compound
- heteroaryl
- membered
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000001875 compounds Chemical class 0.000 claims 40
- 239000000203 mixture Substances 0.000 claims 24
- 150000003839 salts Chemical class 0.000 claims 18
- 239000012453 solvate Substances 0.000 claims 17
- 125000001072 heteroaryl group Chemical group 0.000 claims 12
- 235000003599 food sweetener Nutrition 0.000 claims 11
- 239000003765 sweetening agent Substances 0.000 claims 11
- 125000000217 alkyl group Chemical group 0.000 claims 9
- 125000004452 carbocyclyl group Chemical group 0.000 claims 8
- 125000000623 heterocyclic group Chemical group 0.000 claims 8
- 239000000047 product Substances 0.000 claims 8
- 125000003710 aryl alkyl group Chemical group 0.000 claims 7
- 239000012141 concentrate Substances 0.000 claims 7
- 235000008504 concentrate Nutrition 0.000 claims 7
- 238000009472 formulation Methods 0.000 claims 7
- 125000004446 heteroarylalkyl group Chemical group 0.000 claims 7
- KYQCOXFCLRTKLS-UHFFFAOYSA-N Pyrazine Chemical compound C1=CN=CC=N1 KYQCOXFCLRTKLS-UHFFFAOYSA-N 0.000 claims 6
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims 6
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims 6
- 125000003118 aryl group Chemical group 0.000 claims 6
- 235000013361 beverage Nutrition 0.000 claims 5
- 235000009508 confectionery Nutrition 0.000 claims 5
- 239000000796 flavoring agent Substances 0.000 claims 5
- 239000002671 adjuvant Substances 0.000 claims 4
- 235000019634 flavors Nutrition 0.000 claims 4
- 235000013305 food Nutrition 0.000 claims 4
- PCNDJXKNXGMECE-UHFFFAOYSA-N Phenazine Natural products C1=CC=CC2=NC3=CC=CC=C3N=C21 PCNDJXKNXGMECE-UHFFFAOYSA-N 0.000 claims 3
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims 3
- 125000000753 cycloalkyl group Chemical group 0.000 claims 3
- -1 cycloheteroalkyl Chemical group 0.000 claims 3
- PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical compound C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 claims 3
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims 3
- 125000000547 substituted alkyl group Chemical group 0.000 claims 3
- 125000003107 substituted aryl group Chemical group 0.000 claims 3
- 235000019605 sweet taste sensations Nutrition 0.000 claims 3
- 125000006714 (C3-C10) heterocyclyl group Chemical group 0.000 claims 2
- 125000006570 (C5-C6) heteroaryl group Chemical group 0.000 claims 2
- SERLAGPUMNYUCK-DCUALPFSSA-N 1-O-alpha-D-glucopyranosyl-D-mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O SERLAGPUMNYUCK-DCUALPFSSA-N 0.000 claims 2
- 125000001313 C5-C10 heteroaryl group Chemical group 0.000 claims 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 claims 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical group C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 claims 2
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 2
- 239000008103 glucose Substances 0.000 claims 2
- 239000000905 isomalt Substances 0.000 claims 2
- 235000010439 isomalt Nutrition 0.000 claims 2
- HPIGCVXMBGOWTF-UHFFFAOYSA-N isomaltol Natural products CC(=O)C=1OC=CC=1O HPIGCVXMBGOWTF-UHFFFAOYSA-N 0.000 claims 2
- 235000012054 meals Nutrition 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 239000000820 nonprescription drug Substances 0.000 claims 2
- 235000016709 nutrition Nutrition 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 235000013324 preserved food Nutrition 0.000 claims 2
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- NUFKRGBSZPCGQB-FLBSXDLDSA-N (3s)-3-amino-4-oxo-4-[[(2r)-1-oxo-1-[(2,2,4,4-tetramethylthietan-3-yl)amino]propan-2-yl]amino]butanoic acid;pentahydrate Chemical compound O.O.O.O.O.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C.OC(=O)C[C@H](N)C(=O)N[C@H](C)C(=O)NC1C(C)(C)SC1(C)C NUFKRGBSZPCGQB-FLBSXDLDSA-N 0.000 claims 1
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 claims 1
- AMFYRKOUWBAGHV-UHFFFAOYSA-N 1h-pyrazolo[4,3-b]pyridine Chemical compound C1=CN=C2C=NNC2=C1 AMFYRKOUWBAGHV-UHFFFAOYSA-N 0.000 claims 1
- GAMYYCRTACQSBR-UHFFFAOYSA-N 4-azabenzimidazole Chemical compound C1=CC=C2NC=NC2=N1 GAMYYCRTACQSBR-UHFFFAOYSA-N 0.000 claims 1
- WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims 1
- 239000004377 Alitame Substances 0.000 claims 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
- 108010011485 Aspartame Proteins 0.000 claims 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 1
- QIVBCDIJIAJPQS-SECBINFHSA-N D-tryptophane Chemical compound C1=CC=C2C(C[C@@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-SECBINFHSA-N 0.000 claims 1
- 239000004386 Erythritol Substances 0.000 claims 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 claims 1
- 239000001512 FEMA 4601 Substances 0.000 claims 1
- 229930091371 Fructose Natural products 0.000 claims 1
- 239000005715 Fructose Substances 0.000 claims 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 239000005913 Maltodextrin Substances 0.000 claims 1
- 229920002774 Maltodextrin Polymers 0.000 claims 1
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 claims 1
- 239000004384 Neotame Substances 0.000 claims 1
- HELXLJCILKEWJH-SEAGSNCFSA-N Rebaudioside A Natural products O=C(O[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)[C@@]1(C)[C@@H]2[C@](C)([C@H]3[C@@]4(CC(=C)[C@@](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)[C@H](O)[C@@H](CO)O5)(C4)CC3)CC2)CCC1 HELXLJCILKEWJH-SEAGSNCFSA-N 0.000 claims 1
- 244000228451 Stevia rebaudiana Species 0.000 claims 1
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims 1
- 239000004376 Sucralose Substances 0.000 claims 1
- 229930006000 Sucrose Natural products 0.000 claims 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
- DHXVGJBLRPWPCS-UHFFFAOYSA-N Tetrahydropyran Chemical group C1CCOCC1 DHXVGJBLRPWPCS-UHFFFAOYSA-N 0.000 claims 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 1
- 235000010358 acesulfame potassium Nutrition 0.000 claims 1
- 239000000619 acesulfame-K Substances 0.000 claims 1
- 235000019409 alitame Nutrition 0.000 claims 1
- 108010009985 alitame Proteins 0.000 claims 1
- WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 1
- 230000000845 anti-microbial effect Effects 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 239000000605 aspartame Substances 0.000 claims 1
- 235000010357 aspartame Nutrition 0.000 claims 1
- 229960003438 aspartame Drugs 0.000 claims 1
- 235000008452 baby food Nutrition 0.000 claims 1
- 235000015173 baked goods and baking mixes Nutrition 0.000 claims 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 229940109275 cyclamate Drugs 0.000 claims 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 125000000582 cycloheptyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical compound OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 claims 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 claims 1
- 235000013365 dairy product Nutrition 0.000 claims 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 claims 1
- 235000015071 dressings Nutrition 0.000 claims 1
- 235000015878 dried processed food Nutrition 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- HELXLJCILKEWJH-UHFFFAOYSA-N entered according to Sigma 01432 Natural products C1CC2C3(C)CCCC(C)(C(=O)OC4C(C(O)C(O)C(CO)O4)O)C3CCC2(C2)CC(=C)C21OC(C1OC2C(C(O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OC(CO)C(O)C(O)C1O HELXLJCILKEWJH-UHFFFAOYSA-N 0.000 claims 1
- 235000019414 erythritol Nutrition 0.000 claims 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 1
- 229940009714 erythritol Drugs 0.000 claims 1
- 239000003925 fat Substances 0.000 claims 1
- 235000019197 fats Nutrition 0.000 claims 1
- 239000006261 foam material Substances 0.000 claims 1
- 235000015219 food category Nutrition 0.000 claims 1
- 235000013355 food flavoring agent Nutrition 0.000 claims 1
- 235000011194 food seasoning agent Nutrition 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 235000011306 frozen processed food Nutrition 0.000 claims 1
- 229930182830 galactose Natural products 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 229930182470 glycoside Natural products 0.000 claims 1
- 150000002338 glycosides Chemical class 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000004404 heteroalkyl group Chemical group 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 235000015243 ice cream Nutrition 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- BJHIKXHVCXFQLS-PQLUHFTBSA-N keto-D-tagatose Chemical compound OC[C@@H](O)[C@H](O)[C@H](O)C(=O)CO BJHIKXHVCXFQLS-PQLUHFTBSA-N 0.000 claims 1
- 239000000832 lactitol Substances 0.000 claims 1
- 235000010448 lactitol Nutrition 0.000 claims 1
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims 1
- 229960003451 lactitol Drugs 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000000845 maltitol Substances 0.000 claims 1
- 235000010449 maltitol Nutrition 0.000 claims 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims 1
- 229940035436 maltitol Drugs 0.000 claims 1
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- 229960001855 mannitol Drugs 0.000 claims 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 1
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- 229930189775 mogroside Natural products 0.000 claims 1
- 235000019412 neotame Nutrition 0.000 claims 1
- HLIAVLHNDJUHFG-HOTGVXAUSA-N neotame Chemical compound CC(C)(C)CCN[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 HLIAVLHNDJUHFG-HOTGVXAUSA-N 0.000 claims 1
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- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
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- 239000002667 nucleating agent Substances 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 235000015927 pasta Nutrition 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
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- 239000003755 preservative agent Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- ILVXOBCQQYKLDS-UHFFFAOYSA-N pyridine N-oxide Chemical compound [O-][N+]1=CC=CC=C1 ILVXOBCQQYKLDS-UHFFFAOYSA-N 0.000 claims 1
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- 235000019204 saccharin Nutrition 0.000 claims 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 claims 1
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- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 claims 1
- 235000015067 sauces Nutrition 0.000 claims 1
- 235000011888 snacks Nutrition 0.000 claims 1
- 239000000600 sorbitol Substances 0.000 claims 1
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- 235000014347 soups Nutrition 0.000 claims 1
- 239000003381 stabilizer Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 229940013618 stevioside Drugs 0.000 claims 1
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims 1
- 235000019202 steviosides Nutrition 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 235000019408 sucralose Nutrition 0.000 claims 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims 1
- 239000005720 sucrose Substances 0.000 claims 1
- 238000009495 sugar coating Methods 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
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- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000000811 xylitol Substances 0.000 claims 1
- 235000010447 xylitol Nutrition 0.000 claims 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
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Families Citing this family (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102775396B (zh) * | 2005-11-08 | 2014-10-08 | 沃泰克斯药物股份有限公司 | Atp-结合弹夹转运蛋白的杂环调控剂 |
| US9603848B2 (en) | 2007-06-08 | 2017-03-28 | Senomyx, Inc. | Modulation of chemosensory receptors and ligands associated therewith |
| UA113831C2 (xx) | 2008-07-31 | 2017-03-27 | Способи і проміжні сполуки для одержання підсилювачів солодкого смаку | |
| EP2603098B1 (en) | 2010-08-12 | 2025-08-06 | Firmenich Incorporated | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer |
| KR20200028050A (ko) | 2012-08-06 | 2020-03-13 | 피르메니히 인코포레이티드 | 단맛 향미 개질제 |
| JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
| US20140272068A1 (en) * | 2013-03-14 | 2014-09-18 | Indra Prakash | Beverages containing rare sugars |
| CN106455642B (zh) * | 2014-05-09 | 2021-03-02 | 弗门尼舍有限公司 | 甜味调节剂和调味料的增溶 |
| PL3191438T3 (pl) | 2014-09-11 | 2022-02-14 | Pepsico, Inc. | Wzmacniacz słodkości |
| SG11201803603WA (en) | 2015-10-29 | 2018-05-30 | Senomyx Inc | High intensity sweeteners |
| AU2017246876B2 (en) | 2016-04-06 | 2021-09-23 | The Coca-Cola Company | Sweetness and taste improvement of steviol glycoside or mogroside sweeteners |
| US10494397B2 (en) | 2016-07-15 | 2019-12-03 | Pepsico, Inc. | Rebaudioside analogs |
| US10966447B2 (en) | 2016-07-19 | 2021-04-06 | Pepsico, Inc. | Glucosyringic acid analogs as sweetness profile modifiers |
| US10085472B2 (en) | 2016-08-29 | 2018-10-02 | Pepsico, Inc. | Compositions comprising rebaudioside J |
| WO2018057387A1 (en) | 2016-09-21 | 2018-03-29 | Celanese International Corporation | Acesulfame potassium compositions and processes for producing same |
| DK3319949T3 (da) | 2016-09-21 | 2020-09-28 | Celanese Int Corp | Acesulfam-kalium-sammensætninger og fremgangsmåder til fremstilling af disse |
| ES2824812T5 (en) | 2016-09-21 | 2025-04-08 | Celanese Int Corp | Acesulfame potassium compositions and processes for producing same |
| SMT202000051T1 (it) | 2016-09-21 | 2020-03-13 | Celanese Int Corp | Composizione di acesulfame potassio e procedimenti per la produzione delle stesse |
| MX2019012940A (es) | 2017-05-03 | 2019-12-16 | Firmenich Incorporated | Metodos para producir edulcorantes de alta intensidad. |
| WO2019071182A1 (en) | 2017-10-06 | 2019-04-11 | Cargill, Incorporated | STEVIOL GLYCOSIDE SOLUBILITY AMPLIFIERS |
| US11019837B2 (en) | 2017-11-08 | 2021-06-01 | Pepsico, Inc. | Mouthfeel modulation in reduced and sugar-free beverages using a blend of pectin and xanthan gum |
| US10806165B2 (en) | 2018-04-24 | 2020-10-20 | Stokely-Van Camp, Inc. | Ready-to-drink plant protein beverage product and methods for making same |
| US11700869B2 (en) | 2018-06-27 | 2023-07-18 | Pepsico, Inc. | Mouthfeel enhancing composition |
| EP3814344B1 (en) | 2018-08-07 | 2024-07-24 | Firmenich Incorporated | 5-substituted 4-amino-1h-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof |
| WO2020096905A1 (en) | 2018-11-07 | 2020-05-14 | Firmenich Incorporated | Methods for making high intensity sweeteners |
| KR20210089717A (ko) | 2018-11-07 | 2021-07-16 | 피르메니히 인코포레이티드 | 고강도 감미료의 제조 방법 |
| WO2020193321A1 (en) | 2019-03-28 | 2020-10-01 | Firmenich Sa | Flavor system |
| JP2022525490A (ja) | 2019-04-04 | 2022-05-17 | フイルメニツヒ ソシエテ アノニム | モグロシド化合物およびその使用 |
| CA3135185A1 (en) | 2019-04-06 | 2020-10-15 | Cargill, Incorporated | Sensory modifiers |
| BR112021014587A2 (pt) | 2019-06-28 | 2022-01-04 | Firmenich & Cie | Misturas de gordura, emulsões das mesmas e usos relacionados |
| CN114364265B (zh) | 2019-09-05 | 2025-01-03 | 弗门尼舍有限公司 | 黄烷酮衍生物及其作为甜味增强剂的用途 |
| EP4054575A1 (en) * | 2019-11-06 | 2022-09-14 | DSM IP Assets B.V. | Novel method |
| US20220273011A1 (en) | 2019-11-11 | 2022-09-01 | Firmenich Sa | Gingerol compounds and their use as flavor modifiers |
| US20220361547A1 (en) | 2019-12-13 | 2022-11-17 | Firmenich Incorporated | Taste modifying compositions and uses thereof |
| WO2021118864A1 (en) | 2019-12-13 | 2021-06-17 | Firmenich Incorporated | Taste modifying compositions and uses thereof |
| US20230000122A1 (en) | 2019-12-18 | 2023-01-05 | Firmenich Incorporated | Taste modifying compositions and uses thereof |
| JP2023507887A (ja) | 2019-12-18 | 2023-02-28 | フィルメニッヒ インコーポレイテッド | 味覚修飾組成物およびその使用 |
| WO2021175751A1 (en) | 2020-03-05 | 2021-09-10 | Firmenich Sa | 11-oxo-cucurbitanes and their use as flavor modifiers |
| CN115279206A (zh) | 2020-03-31 | 2022-11-01 | 弗门尼舍有限公司 | 风味剂组合物 |
| US20230148070A1 (en) | 2020-04-17 | 2023-05-11 | Firmenich Sa | Amino acid derivatives and their use as flavor modifiers |
| JP2023525620A (ja) | 2020-05-22 | 2023-06-19 | フイルメニツヒ ソシエテ アノニム | 塩味を和らげる組成物およびその使用 |
| US20230157341A1 (en) | 2020-06-03 | 2023-05-25 | Firmenich Sa | Compositions for reducing off tastes and uses thereof |
| MX2022015148A (es) | 2020-06-24 | 2023-01-11 | Firmenich & Cie | Composiciones edulcorantes y usos de las mismas. |
| US20230225953A1 (en) | 2020-07-14 | 2023-07-20 | Firmenich Sa | Reduction of undesirable taste notes in oral care products |
| WO2022020435A1 (en) | 2020-07-24 | 2022-01-27 | Firmenich Incorporated | Savory taste enhancement via transmembrane region binding |
| EP4125428A1 (en) | 2020-09-22 | 2023-02-08 | Firmenich SA | Wintergreen flavor compositions free of methyl salicylate |
| EP4228433A1 (en) | 2020-10-13 | 2023-08-23 | Firmenich SA | Malonyl steviol glycosides and their comestible use |
| JP2023545892A (ja) | 2020-10-27 | 2023-11-01 | フイルメニツヒ ソシエテ アノニム | 共役ジイン、及びフレーバー改質剤としてのその使用 |
| WO2022115837A1 (en) | 2020-11-24 | 2022-06-02 | Firmenich Incorporated | Kokumi taste enhancement and related screening methods |
| EP4175490A1 (en) | 2020-11-29 | 2023-05-10 | Firmenich SA | Compositions that reduce peroxide off taste and uses thereof |
| US20230397627A1 (en) | 2020-12-23 | 2023-12-14 | Firmenich Sa | Uses of fat blends and emulsions thereof |
| WO2022150445A1 (en) | 2021-01-07 | 2022-07-14 | Conagen Inc. | Compounds and methods for enhancing sweetness of sweeteners |
| JP2024503845A (ja) | 2021-01-13 | 2024-01-29 | フィルメニッヒ インコーポレイテッド | 清涼効果を増強する組成物 |
| JP2024503099A (ja) | 2021-01-15 | 2024-01-24 | フィルメニッヒ インコーポレイテッド | モグロシドを含む甘味料組成物およびその使用 |
| WO2022155668A1 (en) | 2021-01-15 | 2022-07-21 | Firmenich Incorporated | Sweetener compostions comprising siamenoside i and uses thereof |
| EP4266904A1 (en) | 2021-02-10 | 2023-11-01 | Firmenich SA | Fiber blends, sweetened fiber blends, and their comestible use |
| EP4258899A1 (en) | 2021-03-09 | 2023-10-18 | Firmenich SA | Hydroxy- and methoxy-substituted flavones and their use |
| WO2022189156A1 (en) | 2021-03-09 | 2022-09-15 | Firmenich Sa | Hydroxy- and methoxy-substituted flavonoids and their use |
| EP4277474A1 (en) | 2021-04-06 | 2023-11-22 | Firmenich SA | Use of gingerdiol compounds to enhance flavor |
| US20240315299A1 (en) | 2021-04-26 | 2024-09-26 | Firmenich Incorporated | Amide compounds and their use as flavor modifiers |
| BR112023022012A2 (pt) | 2021-04-26 | 2023-12-26 | Firmenich Incorporated | Compostos de amida e seu uso como modificadores de sabor |
| US20250275560A1 (en) | 2021-05-11 | 2025-09-04 | Firmenich Sa | Process of making gingerol compounds and their use as flavor modifiers |
| WO2022248405A1 (en) | 2021-05-24 | 2022-12-01 | Firmenich Sa | Flavored fiber blends and their comestible use |
| JP2024522284A (ja) | 2021-05-28 | 2024-06-13 | フィルメニッヒ インコーポレイテッド | 清涼効果を増強する組成物 |
| JP2024522442A (ja) | 2021-06-02 | 2024-06-21 | フイルメニツヒ ソシエテ アノニム | 脱アセチル化の方法、組成物、およびその使用 |
| US20250040582A1 (en) | 2021-06-23 | 2025-02-06 | Firmenich Sa | Flavor-modifying compositions containing lactase |
| EP4337647A1 (en) | 2021-06-28 | 2024-03-20 | Firmenich Incorporated | Polycationic salts of phenolic compounds and uses thereof |
| JP2024525466A (ja) | 2021-06-29 | 2024-07-12 | フィルメニッヒ インコーポレイテッド | モグロシド化合物およびその食用利用 |
| WO2023274808A1 (en) | 2021-06-29 | 2023-01-05 | Firmenich Sa | Licorice compounds and their use as flavor modifiers |
| WO2023049308A1 (en) | 2021-09-27 | 2023-03-30 | Firmenich Incorporated | Use of vanillyl ethers to modify flavor of distilled spirits |
| EP4362689A1 (en) | 2021-09-27 | 2024-05-08 | Firmenich SA | Flavor compositions containing iron compounds and their use |
| WO2023072604A1 (en) | 2021-11-01 | 2023-05-04 | Firmenich Sa | Composition comprising a nutrient and a taste modulator |
| EP4404767A2 (en) | 2021-11-16 | 2024-07-31 | Firmenich Incorporated | Amide compounds and their use as flavor modifiers |
| EP4416503A1 (en) | 2021-12-07 | 2024-08-21 | Firmenich Incorporated | Reduction of bitter taste of plant proteins and related assays and screening methods |
| EP4418872A1 (en) | 2021-12-20 | 2024-08-28 | Firmenich SA | Encapsulated metal compounds and comestible uses thereof |
| US20250064063A1 (en) | 2021-12-23 | 2025-02-27 | Firmenich Sa | Antimicrobial composition having encapsulated colorant |
| JP2025508354A (ja) | 2022-03-04 | 2025-03-26 | フイルメニツヒ ソシエテ アノニム | ポリメトキシル化フラボノイドの精製方法およびそれから得られる組成物 |
| EP4472947A1 (en) | 2022-03-07 | 2024-12-11 | Firmenich Incorporated | Sweetener compositions |
| JP2025507547A (ja) | 2022-03-10 | 2025-03-21 | フイルメニツヒ ソシエテ アノニム | 甘味料組成物 |
| CN118829632A (zh) | 2022-03-11 | 2024-10-22 | 弗门尼舍公司 | 黄烷酮化合物及其作为风味修饰剂的用途 |
| EP4456737A1 (en) | 2022-03-11 | 2024-11-06 | Firmenich Incorporated | Amide compounds and their use as flavor modifiers |
| EP4472442A1 (en) | 2022-03-25 | 2024-12-11 | Firmenich SA | Fatty acid amides and their use as flavor modifiers |
| US20250204570A1 (en) | 2022-03-28 | 2025-06-26 | Firmenich Sa | Non-animal protein compositions and uses thereof |
| EP4475686A1 (en) | 2022-04-06 | 2024-12-18 | Firmenich Incorporated | Taste modifying compositions and uses thereof |
| CN119183351A (zh) | 2022-04-11 | 2024-12-24 | 弗门尼舍有限公司 | 甜味剂组合物 |
| US20250275559A1 (en) | 2022-05-16 | 2025-09-04 | Firmenich Incorporated | Saturated fatty acids and their use to modify taste |
| EP4492989A1 (en) | 2022-05-16 | 2025-01-22 | Firmenich Incorporated | Unsaturated fatty acids and their use to modify taste |
| CN119300722A (zh) | 2022-06-03 | 2025-01-10 | 弗门尼舍有限公司 | 非动物蛋白组合物中的脂肪减少 |
| CN119325346A (zh) | 2022-06-14 | 2025-01-17 | 弗门尼舍有限公司 | 蛋白质的聚电解质复合物及其用途 |
| WO2023247332A1 (en) | 2022-06-24 | 2023-12-28 | Firmenich Sa | Taste modifying compositions and uses thereof |
| WO2024011086A1 (en) | 2022-07-07 | 2024-01-11 | Firmenich Incorporated | Compositions that enhance the cooling effect |
| WO2024041974A1 (en) | 2022-08-22 | 2024-02-29 | Firmenich Sa | Gel compositions and their use in seafood analogue products |
| WO2024091457A1 (en) | 2022-10-26 | 2024-05-02 | Firmenich Incorporated | Taste modifying compositions and uses thereof |
| EP4547034A1 (en) | 2022-10-26 | 2025-05-07 | Firmenich SA | Extrusion methods and flavored products formed thereby |
| WO2024094523A1 (en) | 2022-11-01 | 2024-05-10 | Firmenich Sa | Low-calorie composition for flavor modification |
| EP4601483A1 (en) | 2022-12-23 | 2025-08-20 | Firmenich Incorporated | Beta-cyclodextrin and its use to modify flavor |
| CN120513026A (zh) | 2023-01-09 | 2025-08-19 | 弗门尼舍有限公司 | 植物纤维用于改善发酵产品风味的用途 |
| EP4608805A1 (en) * | 2023-01-12 | 2025-09-03 | Firmenich SA | Process for preparation of sulfamoyl chloride |
| EP4665157A1 (en) | 2023-02-15 | 2025-12-24 | Firmenich SA | Thermoresponsive gel composition and uses thereof |
| EP4630413A1 (en) | 2023-02-25 | 2025-10-15 | Firmenich Incorporated | Flavanone compounds and their use as flavor modifiers |
| CN120916646A (zh) | 2023-03-23 | 2025-11-07 | 弗门尼舍公司 | 香兰基醚修饰风味的用途 |
| EP4661689A1 (en) | 2023-03-24 | 2025-12-17 | Firmenich SA | Microparticles containing algal proteins and uses thereof |
| CN120981169A (zh) | 2023-03-29 | 2025-11-18 | 弗门尼舍公司 | 脂肪酸用于修饰风味的用途 |
| WO2024208837A1 (en) | 2023-04-04 | 2024-10-10 | Firmenich Sa | Polysaccharide compositions and their comestible use |
| WO2024227789A1 (en) | 2023-05-03 | 2024-11-07 | Firmenich Sa | Encapsulated phenolic compounds and their comestible use |
| WO2024251755A1 (en) | 2023-06-09 | 2024-12-12 | Dsm-Firmenich Ag | Compositions for reducing off notes and uses thereof |
| EP4480319A1 (en) | 2023-06-22 | 2024-12-25 | DSM-Firmenich AG | Granola cluster |
| WO2025067974A1 (en) | 2023-09-26 | 2025-04-03 | Firmenich Sa | Vegan cheese compositions and methods of making the same |
| WO2025073683A1 (en) | 2023-10-04 | 2025-04-10 | Firmenich Sa | Flavanone compounds and their use as flavor modifiers |
| WO2025125286A1 (en) | 2023-12-13 | 2025-06-19 | Firmenich Sa | Biopolymer compositions and their use in foamed compositions |
| WO2025132821A1 (en) | 2023-12-19 | 2025-06-26 | Firmenich Sa | Comestible products having high fiber and low sugar |
| WO2025132803A1 (en) | 2023-12-20 | 2025-06-26 | Firmenich Sa | 3-hydroxybenzoic acid and its use as a flavor modifier |
| WO2025191050A1 (en) | 2024-03-15 | 2025-09-18 | Firmenich Sa | Lipid particles and their comestible use |
| WO2025221883A1 (en) | 2024-04-17 | 2025-10-23 | Firmenich Incorporated | Taste modifying compositions and uses thereof |
| WO2025230968A1 (en) | 2024-04-30 | 2025-11-06 | Firmenich Incorporated | Ketone compounds for enhancing alcohol perception |
Family Cites Families (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB951651A (en) | 1960-02-17 | 1964-03-11 | Shell Res Ltd | Substituted benzonitriles, their preparation and compositions containing them |
| US3278532A (en) | 1964-07-06 | 1966-10-11 | Sandoz Ag | Dioxybenzothiadiazines |
| US3857972A (en) | 1971-03-10 | 1974-12-31 | Int Flavors & Fragrances Inc | Flavoring with an oxocyclic pyrimidine |
| US3843804A (en) | 1971-03-10 | 1974-10-22 | Int Flavors & Fragrances Inc | Novel flavoring compositions and processes |
| LU64388A1 (enExample) | 1971-12-02 | 1973-07-16 | ||
| FI54312C (fi) | 1972-05-09 | 1978-11-10 | Sumitomo Chemical Co | Foerfarande foer framstaellning av tieno-(2,3-d)pyrimidinderivat med avsoendring av urinsyra i urin utoekande |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3960860A (en) | 1973-01-08 | 1976-06-01 | International Flavors & Fragrances Inc. | 2-Methyl-5,7-dihydrothieno-[3,4d]-pyrimidine |
| US3966965A (en) | 1973-03-23 | 1976-06-29 | American Home Products Corporation | Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions |
| US4036837A (en) | 1973-03-23 | 1977-07-19 | American Home Products Corporation | 2 Alkoxyoxamoyl-pyrazines |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| GB1570494A (en) | 1975-11-28 | 1980-07-02 | Ici Ltd | Thienopyrimidine derivatives and their use as pesticides |
| US4137325A (en) | 1977-03-17 | 1979-01-30 | American Home Products Corporation | Antisecretory oxamic acid esters |
| US4196207A (en) | 1977-05-23 | 1980-04-01 | Ici Australia Limited | Process for controlling eradicating or preventing infestations of animals by Ixodid ticks |
| ES472163A1 (es) | 1978-07-28 | 1979-03-16 | Consejo Superior Investigacion | Ÿun nuevo procedimiento para la obtencion de 5,5-dioxido de 7-amino-2h-4h-vic-triazolo (4,5-c) (1,2,6) tiadiazinaÿ |
| IE51802B1 (en) | 1979-12-03 | 1987-04-01 | Fujisawa Pharmaceutical Co | Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them |
| JPS5951290A (ja) | 1982-09-14 | 1984-03-24 | Dai Ichi Seiyaku Co Ltd | ベンゾチエノイミダゾピリミジンジオン化合物 |
| ES8507558A1 (es) | 1984-03-30 | 1985-09-01 | Consejo Superior Investigacion | Procedimiento para la preparacion de aminociclotiadiazinas |
| GB8504253D0 (en) | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| US4672116A (en) | 1985-12-20 | 1987-06-09 | Ortho Pharmaceutical Corporation | Substituted 5,6-dialkoxyquinazoline derivatives |
| JPS6387959A (ja) | 1986-10-01 | 1988-04-19 | Sanyo Kokusaku Pulp Co Ltd | ステビア甘味料の呈味性改善法 |
| US4960870A (en) | 1987-02-11 | 1990-10-02 | Ciba-Geigy Corporation | Heavy metal complex azo dyes containing a benzothiophene-1,1-dioxide, 2,1-benzothiazine-2,2-dioxide, 1,4-benzothiazine-1,1-dioxide or thienopyridine-1,1-dioxide coupling component |
| AU617121B2 (en) * | 1987-07-17 | 1991-11-21 | Nutrasweet Company, The | Substituted guanidines containing a tetrazolyl moiety and their use as high potency sweetening agents |
| US5380541A (en) | 1987-08-07 | 1995-01-10 | Tate & Lyle Public Limited Company | Sucralose compositions |
| DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| JPH02238856A (ja) | 1989-03-14 | 1990-09-21 | Mitajiri Kagaku Kogyo Kk | ミラクリンを有効成分とする矯味・調味料及びこれを含有する飲食品 |
| US5192785A (en) | 1989-09-03 | 1993-03-09 | A. H. Robins Company, Incorporated | Sulfamates as antiglaucoma agents |
| US5504095A (en) | 1990-09-19 | 1996-04-02 | Pfizer Inc. | Aminobenzosultam derivatives as lipoxygenase inhibitors |
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| IL102764A0 (en) | 1991-08-16 | 1993-01-31 | Merck & Co Inc | Quinazoline derivatives,and pharmaceutical compositions containing them |
| PT100905A (pt) | 1991-09-30 | 1994-02-28 | Eisai Co Ltd | Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem |
| GB9127188D0 (en) | 1991-12-21 | 1992-02-19 | Smithkline Beecham Plc | Novel compounds |
| KR970010069B1 (ko) | 1992-08-24 | 1997-06-20 | 주식회사 럭키 | 신규 세팔로스포린계 항생제 및 이의 제조방법 |
| ATE186222T1 (de) | 1995-03-14 | 1999-11-15 | Siemens Ag | Ultraschallzerstäuber mit abnehmbarer präzisionsdosiereinheit |
| ES2177771T3 (es) | 1995-03-14 | 2002-12-16 | Siemens Ag | Dispositivo atomizador ultrasonico con unidad desmontable de dosificacion de precision. |
| US6046206A (en) | 1995-06-07 | 2000-04-04 | Cell Pathways, Inc. | Method of treating a patient having a precancerous lesions with amide quinazoline derivatives |
| DE19632423A1 (de) | 1996-08-12 | 1998-02-19 | Merck Patent Gmbh | Thienopyrimidine |
| ATE260048T1 (de) | 1996-12-20 | 2004-03-15 | Nutrinova Gmbh | Verfahren zur verstärkung der süsskraft und zur geschmacksverbesserung einer mischung hochintensiver süssstoffe |
| KR100220953B1 (ko) | 1996-12-31 | 1999-10-01 | 김영환 | 아미드 또는 이미드를 도입한 ArF 감광막 수지 |
| GB9711650D0 (en) | 1997-06-05 | 1997-07-30 | Pfizer Ltd | Compounds useful in therapy |
| US5954047A (en) | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| US5990117A (en) | 1998-04-15 | 1999-11-23 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives |
| EP1082311A1 (en) | 1998-05-28 | 2001-03-14 | Parker Hughes Institute | Quinazolines for treating brain tumor |
| US6169118B1 (en) | 1998-11-12 | 2001-01-02 | Block Drug Company, Inc. | Flavor blend for masking unpleasant taste of zinc compounds |
| JP2003500397A (ja) | 1999-05-19 | 2003-01-07 | スミスクライン ビーチャム パブリック リミテッド カンパニー | Ｍｒｓ阻害剤としての２−ｎｈ−ピリドンおよびピリミドン |
| GB9915995D0 (en) | 1999-07-09 | 1999-09-08 | Ahmed S | Non-steroidal sulphamate compounds for use as oestrone sulphatase inhibitors |
| JP3523166B2 (ja) | 1999-09-02 | 2004-04-26 | 高砂香料工業株式会社 | 食品香料劣化防止剤、食品香料劣化防止方法およびその食品香料劣化防止剤を含有する食品 |
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| AU5125801A (en) | 2000-04-07 | 2001-10-23 | Senomyx Inc | T2r taste receptors and genes encoding same |
| US6468576B1 (en) | 2000-06-23 | 2002-10-22 | Nestec S.A. | Frozen slush liquid concentrate and method of making same |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US6852862B2 (en) | 2001-03-02 | 2005-02-08 | Sumika Fine Chemicals Co., Ltd. | Process for producing quinoline-3-carboxylic acid compound |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| EP2327985B2 (en) | 2001-06-26 | 2019-08-21 | Senomyx, Inc. | T1R Hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| AU2002320294B2 (en) | 2001-07-03 | 2009-01-15 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Mammalian sweet and amino acid heterodimeric taste receptors |
| US20060134693A1 (en) | 2001-07-06 | 2006-06-22 | Guy Servant | Olfactory cyclic nucleotide-gated channel cell-based assays to identify T1R and T2R taste modulators |
| US7851004B2 (en) | 2001-07-19 | 2010-12-14 | San-Ei Gen F.F.I., Inc. | Taste-improving composition and application of the same |
| WO2003022214A2 (en) | 2001-09-06 | 2003-03-20 | Millennium Pharmaceuticals, Inc. | Piperazine and homopiperazine compounds |
| ES2274111T3 (es) | 2001-12-14 | 2007-05-16 | Merck Frosst Canada Ltd. | Quinolinas como ligandos del receptor de prostaglandinas. |
| AU2002361846A1 (en) | 2001-12-21 | 2003-07-15 | Bayer Pharmaceuticals Corporation | Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents |
| GB0206033D0 (en) | 2002-03-14 | 2002-04-24 | Pfizer Ltd | Compounds useful in therapy |
| US20040127435A1 (en) | 2002-08-02 | 2004-07-01 | Regents Of The University Of California | Uses for inhibitors of inosine monophosphate dehydrogenase |
| GB0230015D0 (en) | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
| DE10324548A1 (de) | 2003-05-28 | 2004-12-16 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Diätisches Lebensmittel bei einer gewichtskontrollierenden bzw. gewichtsreduzierenden Ernährung |
| CA2535036C (en) | 2003-08-06 | 2015-11-24 | Senomyx, Inc. | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
| WO2005016889A1 (en) | 2003-08-08 | 2005-02-24 | Virginia Commonwealth University | Compounds having antiestrogenic and tissue selective estrogenic properties |
| US20050196503A1 (en) | 2004-03-05 | 2005-09-08 | Sunil Srivastava | High-intensity sweetener-polyol compositions |
| EP1753864A2 (en) | 2004-04-14 | 2007-02-21 | Monell Chemical Senses Center | Taste receptors of the t1r family from domestic dog |
| CA2569763C (en) | 2004-06-08 | 2013-03-12 | Decode Chemistry, Inc. | 2,4-diaminoquinazolines for spinal muscular atrophy |
| US20060045953A1 (en) | 2004-08-06 | 2006-03-02 | Catherine Tachdjian | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers |
| US20060083695A1 (en) | 2004-10-15 | 2006-04-20 | Ajinomoto Co. Inc | Sweetener composition |
| WO2006076102A2 (en) | 2004-12-10 | 2006-07-20 | The Regents Of The University Of California | Fluorescent nucleoside analogs that mimic naturally occurring nucleosides |
| PL1828199T3 (pl) | 2004-12-17 | 2009-10-30 | Hoffmann La Roche | Pochodne tieno-pirydyny jako alosteryczne wzmacniacze gaba-b |
| AR052477A1 (es) | 2005-02-04 | 2007-03-21 | Senomyx Inc | Moleculas que comprenden restos organicos conectados como modificadores del sabor para composiciones comestibles |
| BRPI0607006B1 (pt) | 2005-02-04 | 2017-05-16 | Senomyx Inc | compostos que compreendem funções orgânicas de hetero arilas ligadas e seus usos como novos modificadores, flavorizantes e promotores do sabor umami para composições comestíveis |
| US8796441B2 (en) | 2005-04-13 | 2014-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human sweet and umami taste receptor variants |
| EP1874753A2 (en) | 2005-04-14 | 2008-01-09 | Smithkline Beecham Corporation | Compounds, compositions and methods |
| RU2007143161A (ru) | 2005-05-25 | 2009-07-10 | Вайет (Us) | Способы синтеза замещенных 3-цианохинов и их продуктов |
| TW200715993A (en) | 2005-06-15 | 2007-05-01 | Senomyx Inc | Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers |
| JP2007007591A (ja) | 2005-07-01 | 2007-01-18 | Mikuni Corp | 電解水及びその製造方法 |
| CN101277939A (zh) | 2005-09-09 | 2008-10-01 | 布里斯托尔-迈尔斯斯奎布公司 | 无环ikur抑制剂 |
| JP5342878B2 (ja) | 2005-10-20 | 2013-11-13 | セノミクス・インコーポレーテッド | キメラヒト甘味‐旨味および旨味‐甘味味覚受容体 |
| US8506956B2 (en) | 2005-10-31 | 2013-08-13 | Kaneka Corporation | Method for stabilizing reduced coenzyme Q10 |
| BRPI0620462A2 (pt) | 2005-12-22 | 2011-11-16 | Astrazeneca Ab | composto, processo para preparar um composto, composição farmacêutica, uso de um composto, e,métodos para produzir um efeito inibidor de b-raf e um efeito anti-cáncer em um animal de sangue quente, e para tratar uma doença |
| AU2007271486A1 (en) | 2006-07-05 | 2008-01-10 | Merck Patent Gmbh | Sulfamate benzothiophene derivatives |
| WO2008024364A2 (en) * | 2006-08-22 | 2008-02-28 | Redpoint Bio Corporation | Heterocyclic compounds as sweetener enhancers |
| US7928111B2 (en) | 2007-06-08 | 2011-04-19 | Senomyx, Inc. | Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors |
| US8633186B2 (en) | 2007-06-08 | 2014-01-21 | Senomyx Inc. | Modulation of chemosensory receptors and ligands associated therewith |
| US9603848B2 (en) | 2007-06-08 | 2017-03-28 | Senomyx, Inc. | Modulation of chemosensory receptors and ligands associated therewith |
| UA113831C2 (xx) | 2008-07-31 | 2017-03-27 | Способи і проміжні сполуки для одержання підсилювачів солодкого смаку | |
| RU2511315C2 (ru) * | 2008-07-31 | 2014-04-10 | Синомикс, Инк. | Композиции, содержащие усилители сладкого вкуса, и способы их получения |
| PE20130211A1 (es) | 2010-04-02 | 2013-03-22 | Senomyx Inc | Modificador del sabor dulce |
| CN102958381B (zh) | 2010-06-29 | 2015-08-05 | 弗门尼舍有限公司 | 活性成分递送系统 |
| EP2603098B1 (en) * | 2010-08-12 | 2025-08-06 | Firmenich Incorporated | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer |
| US8785481B2 (en) * | 2010-09-29 | 2014-07-22 | Merck Sharp & Dohme Corp. | Ether benzotriazole derivatives |
| EP2629617A4 (en) * | 2010-10-19 | 2014-08-27 | Elcelyx Therapeutics Inc | THERAPIES BASED ON CHEMOSOUS RECEPTOR LIGANDS |
| KR20200028050A (ko) | 2012-08-06 | 2020-03-13 | 피르메니히 인코포레이티드 | 단맛 향미 개질제 |
| EP2695899A1 (de) | 2012-08-06 | 2014-02-12 | Basf Se | Polyharnstoff-Elastomere mit erhöhter Chemikalienbeständigkeit |
| JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
| KR102265636B1 (ko) | 2013-03-13 | 2021-06-16 | 디에스엠 뉴트리셔널 프라덕츠 아게 | 우레아/오일 복합체로부터 우레아 및 오일의 회수 |
-
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