PE20191204A1 - Modificador del sabor dulce - Google Patents

Modificador del sabor dulce

Info

Publication number
PE20191204A1
PE20191204A1 PE2019001236A PE2019001236A PE20191204A1 PE 20191204 A1 PE20191204 A1 PE 20191204A1 PE 2019001236 A PE2019001236 A PE 2019001236A PE 2019001236 A PE2019001236 A PE 2019001236A PE 20191204 A1 PE20191204 A1 PE 20191204A1
Authority
PE
Peru
Prior art keywords
sweet flavor
compounds
flavor modifier
thadiazin
dioxido
Prior art date
Application number
PE2019001236A
Other languages
English (en)
Inventor
Catherine Tachdjian
Sara Werner
Vincent Darmohusodo
Jeff Yamamoto
Original Assignee
Firmenich Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich Incorporated filed Critical Firmenich Incorporated
Publication of PE20191204A1 publication Critical patent/PE20191204A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/56Flavouring or bittering agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88Taste or flavour enhancing agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/35Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15Six-membered rings
    • C07D285/16Thiadiazines; Hydrogenated thiadiazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

REFERIDO A COMPUESTOS DE FORMULA (Ia) DONDE m ES DE 2 A 4; n ES DE 0 A 2; q ES 0; X ES UN ENLACE COVALENTE; Y ES ALQUILO C1-C12 OPCIONALMENTE SUSTITUIDO, CARBOCICLILO C3-C8 OPCIONALMENTE SUSTITUIDO, ENTRE OTROS. SON COMPUESTOS PREFERIDOS: (S)-1-(3-(((4-AMINO-2,2-DIOXIDO-1H-BENZO[c][1,2,6]TIADIAZIN-5-IL)OXI)METIL)PIPERIDIN-1-IL)-2-CICLOPROPILETANONA; (S)-(3-(((4-AMINO-2,2-DIOXIDO-1H-BENZO[c][1,2,6]TIADIAZIN-5-IL)OXI)METIL)PIPERIDIN-1-IL)(PIRIDIN-4-IL)METANONA; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION Y METODOS PARA MODULAR EL SABOR DULCE DE OTRAS COMPOSICIONES. DICHOS COMPUESTOS SON UTILES COMO MODIFICADORES DEL SABOR DULCE
PE2019001236A 2012-08-06 2013-08-05 Modificador del sabor dulce PE20191204A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261679912P 2012-08-06 2012-08-06
US201361779502P 2013-03-13 2013-03-13

Publications (1)

Publication Number Publication Date
PE20191204A1 true PE20191204A1 (es) 2019-09-10

Family

ID=50068508

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2015000136A PE20150626A1 (es) 2012-08-06 2013-08-05 Modificador del sabor dulce
PE2019001236A PE20191204A1 (es) 2012-08-06 2013-08-05 Modificador del sabor dulce

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2015000136A PE20150626A1 (es) 2012-08-06 2013-08-05 Modificador del sabor dulce

Country Status (23)

Country Link
US (5) US8877922B2 (es)
EP (2) EP2880031B1 (es)
JP (2) JP6551936B2 (es)
KR (3) KR20150041040A (es)
CN (1) CN104603132B (es)
AR (1) AR092062A1 (es)
AU (1) AU2013299859B2 (es)
BR (1) BR112015002380B1 (es)
CA (1) CA2879554A1 (es)
CL (1) CL2015000268A1 (es)
CO (1) CO7400867A2 (es)
ES (1) ES2806606T3 (es)
HK (1) HK1209728A1 (es)
IL (1) IL236794B (es)
MX (1) MX354835B (es)
NZ (1) NZ703926A (es)
PE (2) PE20150626A1 (es)
PH (3) PH12015500242B1 (es)
RU (2) RU2666534C2 (es)
SA (3) SA515360953B1 (es)
SG (1) SG11201500880UA (es)
TW (2) TW201713222A (es)
WO (1) WO2014025706A1 (es)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1945632E (pt) * 2005-11-08 2013-12-24 Vertex Pharma Moduladores heterocíclicos de transportadores de cassete de ligação a atp
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
ES2647947T3 (es) 2008-07-31 2017-12-27 Senomyx, Inc. Procesos y productos intermedios para la preparación de potenciadores del sabor dulce
CN106107406B (zh) 2010-08-12 2020-06-09 弗门尼舍公司 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物
CN104603132B (zh) 2012-08-06 2020-02-21 弗门尼舍公司 甜味调节剂
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US20140272068A1 (en) * 2013-03-14 2014-09-18 Indra Prakash Beverages containing rare sugars
EP3142498B1 (en) * 2014-05-09 2018-06-20 Firmenich SA Solubilization of a sweet modulator and flavor
CA2960400A1 (en) 2014-09-11 2016-03-17 Pepsico, Inc. Phloroglucinol and structural analogs thereof as sweetness enhancers
CA3003163A1 (en) 2015-10-29 2017-05-04 Senomyx, Inc. High intensity sweeteners
US11751592B2 (en) 2016-04-06 2023-09-12 The Coca-Cola Company Sweetness and taste improvement of steviol glycoside or mogroside sweeteners
US10494397B2 (en) 2016-07-15 2019-12-03 Pepsico, Inc. Rebaudioside analogs
US10966447B2 (en) 2016-07-19 2021-04-06 Pepsico, Inc. Glucosyringic acid analogs as sweetness profile modifiers
US10085472B2 (en) 2016-08-29 2018-10-02 Pepsico, Inc. Compositions comprising rebaudioside J
US10029998B2 (en) 2016-09-21 2018-07-24 Celanese International Corporation Acesulfame potassium compositions and processes for producing same
DK3317260T3 (da) 2016-09-21 2020-01-27 Celanese Int Corp Acesulfam-kalium-sammensætninger og fremgangsmåder til fremstilling af disse
LT3319949T (lt) 2016-09-21 2020-11-10 Celanese International Corporation Kalio acesulfamo kompozicijos ir jų gamybos būdas
CN108884064A (zh) 2016-09-21 2018-11-23 国际人造丝公司 乙酰舒泛钾组合物和其生产方法
SG11201910136RA (en) 2017-05-03 2019-11-28 Firmenich Incorporated Methods for making high intensity sweeteners
WO2019071187A1 (en) 2017-10-06 2019-04-11 Cargill, Incorporated STABILIZED GLYCOSIDE COMPOSITIONS OF STEVIOL AND USES THEREOF
US11019837B2 (en) 2017-11-08 2021-06-01 Pepsico, Inc. Mouthfeel modulation in reduced and sugar-free beverages using a blend of pectin and xanthan gum
US10806165B2 (en) 2018-04-24 2020-10-20 Stokely-Van Camp, Inc. Ready-to-drink plant protein beverage product and methods for making same
US11700869B2 (en) 2018-06-27 2023-07-18 Pepsico, Inc. Mouthfeel enhancing composition
CN112703193A (zh) 2018-08-07 2021-04-23 弗门尼舍公司 5-取代的4-氨基-1H-苯并[c][1,2,6]噻二嗪2,2-二氧化物及其制剂和用途
EP3860369B1 (en) 2019-03-28 2024-05-08 Firmenich SA Flavor system
WO2020200916A1 (en) 2019-04-04 2020-10-08 Firmenich Sa Mogroside compounds and uses thereof
BR112021019811A2 (pt) 2019-04-06 2021-12-07 Cargill Inc Composição de glicosídeo de esteviol, bebida, métodos para reduzir um atributo sensorial indesejável de uma solução aquosa de glicosídeo de esteviol, para reduzir a persistência de doçura de um componente de glicosídeo de esteviol em uma composição comestível e para reduzir o amargor de um componente de glicosídeo de esteviol em uma composição comestível, e, soluções aquosa de glicosídeo de esteviol com reduzida persistência de doçura e aquosa de glicosídeo de esteviol com reduzido amargor
WO2020260628A1 (en) 2019-06-28 2020-12-30 Firmenich Sa Fat blends, emulsions thereof, and related uses
JP2022547292A (ja) 2019-09-05 2022-11-11 フイルメニツヒ ソシエテ アノニム フラバノン誘導体及び甘味増強剤としてのフラバノン誘導体の使用
EP4054575A1 (en) * 2019-11-06 2022-09-14 DSM IP Assets B.V. Novel method
CN113226058A (zh) 2019-11-11 2021-08-06 弗门尼舍有限公司 姜酚化合物及其作为风味改良剂的用途
WO2021119035A1 (en) 2019-12-13 2021-06-17 Firmenich Incorporated Taste modifying compositions and uses thereof
US20230028760A1 (en) 2019-12-13 2023-01-26 Firmenich Incorporated Taste modifying compositions and uses thereof
JP2023507887A (ja) 2019-12-18 2023-02-28 フィルメニッヒ インコーポレイテッド 味覚修飾組成物およびその使用
US20230000122A1 (en) 2019-12-18 2023-01-05 Firmenich Incorporated Taste modifying compositions and uses thereof
US20230061835A1 (en) 2020-03-05 2023-03-02 Firmenich Sa 11-oxo cucurbitanes and their use as flavor modifiers
WO2021198199A1 (en) 2020-03-31 2021-10-07 Firmenich Sa Flavor composition
US20230148070A1 (en) 2020-04-17 2023-05-11 Firmenich Sa Amino acid derivatives and their use as flavor modifiers
JP2023525620A (ja) 2020-05-22 2023-06-19 フイルメニツヒ ソシエテ アノニム 塩味を和らげる組成物およびその使用
BR112022016411A2 (pt) 2020-06-03 2022-10-11 Firmenich & Cie Composições para reduzir gostos desagradáveis e usos das mesmas
CN115701912A (zh) 2020-06-24 2023-02-14 弗门尼舍有限公司 赋甜组合物及其用途
CN115551598A (zh) 2020-07-14 2022-12-30 弗门尼舍有限公司 口腔护理产品中的不希望的味道调性的减少
EP4162273A1 (en) 2020-07-24 2023-04-12 Firmenich Incorporated Savory taste enhancement via transmembrane region binding
WO2022063488A1 (en) 2020-09-22 2022-03-31 Firmenich Sa Wintergreen flavor compositions free of methyl salicylate
CN114901081B (zh) 2020-10-13 2023-03-24 弗门尼舍有限公司 丙二酰基甜菊醇糖苷及其可食用用途
EP4161292A1 (en) 2020-10-27 2023-04-12 Firmenich SA Conjugated diynes and their use as flavor modifiers
WO2022115837A1 (en) 2020-11-24 2022-06-02 Firmenich Incorporated Kokumi taste enhancement and related screening methods
US20240000120A1 (en) 2020-11-29 2024-01-04 Firmenich Sa Compositions that reduce peroxide off taste and uses thereof
US20230397627A1 (en) 2020-12-23 2023-12-14 Firmenich Sa Uses of fat blends and emulsions thereof
WO2022150445A1 (en) 2021-01-07 2022-07-14 Conagen Inc. Compounds and methods for enhancing sweetness of sweeteners
US20240058238A1 (en) 2021-01-13 2024-02-22 Firmenich Incorporated Compositions that enhance the cooling effect
US20240065302A1 (en) 2021-01-15 2024-02-29 Firmenich Incorporated Sweetener compositions comprising mogrosides and uses thereof
EP4258895A1 (en) 2021-01-15 2023-10-18 Firmenich Incorporated Sweetener compostions comprising siamenoside i and uses thereof
EP4266904A1 (en) 2021-02-10 2023-11-01 Firmenich SA Fiber blends, sweetened fiber blends, and their comestible use
EP4258899A1 (en) 2021-03-09 2023-10-18 Firmenich SA Hydroxy- and methoxy-substituted flavones and their use
WO2022189156A1 (en) 2021-03-09 2022-09-15 Firmenich Sa Hydroxy- and methoxy-substituted flavonoids and their use
WO2022214275A1 (en) 2021-04-06 2022-10-13 Firmenich Sa Use of gingerdiol compounds to enhance flavor
WO2022231918A1 (en) 2021-04-26 2022-11-03 Firmenich Incorporated Amide compounds and their use as flavor modifiers
EP4304386A1 (en) 2021-04-26 2024-01-17 Firmenich Incorporated Amide compounds and their use as flavor modifiers
EP4307919A2 (en) 2021-05-11 2024-01-24 Firmenich SA Process of making gingerol compounds and their use as flavor modifiers
EP4307910A1 (en) 2021-05-24 2024-01-24 Firmenich SA Flavored fiber blends and their comestible use
EP4304385A1 (en) 2021-05-28 2024-01-17 Firmenich Incorporated Compositions that enhance the cooling effect
BR112023022013A2 (pt) 2021-06-02 2023-12-26 Firmenich & Cie Processo de desacetilação, composições e usos das mesmas
BR112023024139A2 (pt) 2021-06-23 2024-01-30 Firmenich & Cie Composições modificadoras de sabor que contêm lactase
BR112023026922A2 (pt) 2021-06-28 2024-03-05 Firmenich Incorporated Sais policatiônicos de compostos fenólicos e usos dos mesmos
WO2023278226A1 (en) 2021-06-29 2023-01-05 Firmenich Incorporated Mogroside compounds and their comestible use
CN117651498A (zh) 2021-06-29 2024-03-05 弗门尼舍有限公司 甘草化合物及其作为风味修饰剂的用途
CN118043443A (zh) 2021-09-27 2024-05-14 弗门尼舍公司 香草基醚用于修饰蒸馏酒的风味的用途
WO2023046914A1 (en) 2021-09-27 2023-03-30 Firmenich Sa Flavor compositions containing iron compounds and their use
WO2023072604A1 (en) 2021-11-01 2023-05-04 Firmenich Sa Composition comprising a nutrient and a taste modulator
WO2023091315A2 (en) 2021-11-16 2023-05-25 Firmenich Incorporated Amide compounds and their use as flavor modifiers
WO2023107904A1 (en) 2021-12-07 2023-06-15 Firmenich Incorporated Reduction of bitter taste of plant proteins and related assays and screening methods
WO2023118002A1 (en) 2021-12-20 2023-06-29 Firmenich Sa Encapsulated metal compounds and comestible uses thereof
WO2023117643A1 (en) 2021-12-23 2023-06-29 Firmenich Sa Antimicrobial composition having encapsulated colorant
WO2023165764A1 (en) 2022-03-04 2023-09-07 Firmenich Sa Purification process for polymethoxylated flavonoids and compositions obtained therefrom
WO2023172415A1 (en) 2022-03-07 2023-09-14 Firmenich Incorporated Sweetener compositions
WO2023169995A1 (en) 2022-03-10 2023-09-14 Firmenich Sa Sweetener compositions
WO2023172372A1 (en) 2022-03-11 2023-09-14 Firmenich Incorporated Amide compounds and their use as flavor modifiers
WO2023172394A1 (en) 2022-03-11 2023-09-14 Firmenich Incorporated Flavanone compounds and their use as flavor modifiers
WO2023180063A1 (en) 2022-03-25 2023-09-28 Firmenich Sa Fatty acid amides and their use as flavor modifiers
WO2023186792A1 (en) 2022-03-28 2023-10-05 Firmenich Sa Non-animal protein compositions and uses thereof
WO2023196128A1 (en) 2022-04-06 2023-10-12 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2023198436A2 (en) 2022-04-11 2023-10-19 Firmenich Sa Sweetener compositions
WO2023224812A1 (en) 2022-05-16 2023-11-23 Firmenich Incorporated Unsaturated fatty acids and their use to modify taste
WO2023224814A1 (en) 2022-05-16 2023-11-23 Firmenich Incorporated Saturated fatty acids and their use to modify taste
WO2023232968A1 (en) 2022-06-03 2023-12-07 Firmenich Sa Fat reduction in non-animal protein compositions
WO2023242177A1 (en) 2022-06-14 2023-12-21 Firmenich Sa Polyelectrolyte complexes of proteins and uses thereof
WO2023247332A1 (en) 2022-06-24 2023-12-28 Firmenich Sa Taste modifying compositions and uses thereof
WO2024011086A1 (en) 2022-07-07 2024-01-11 Firmenich Incorporated Compositions that enhance the cooling effect
WO2024041974A1 (en) 2022-08-22 2024-02-29 Firmenich Sa Gel compositions and their use in seafood analogue products
WO2024091457A1 (en) 2022-10-26 2024-05-02 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2024089025A1 (en) 2022-10-26 2024-05-02 Firmenich Sa Extrusion methods and flavored products formed thereby
WO2024094523A1 (en) 2022-11-01 2024-05-10 Firmenich Sa Low-calorie composition for flavor modification

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB951651A (en) 1960-02-17 1964-03-11 Shell Res Ltd Substituted benzonitriles, their preparation and compositions containing them
US3278532A (en) 1964-07-06 1966-10-11 Sandoz Ag Dioxybenzothiadiazines
US3857972A (en) 1971-03-10 1974-12-31 Int Flavors & Fragrances Inc Flavoring with an oxocyclic pyrimidine
US3843804A (en) 1971-03-10 1974-10-22 Int Flavors & Fragrances Inc Novel flavoring compositions and processes
LU64388A1 (es) 1971-12-02 1973-07-16
FI54312C (fi) 1972-05-09 1978-11-10 Sumitomo Chemical Co Foerfarande foer framstaellning av tieno-(2,3-d)pyrimidinderivat med avsoendring av urinsyra i urin utoekande
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3960860A (en) 1973-01-08 1976-06-01 International Flavors & Fragrances Inc. 2-Methyl-5,7-dihydrothieno-[3,4d]-pyrimidine
US4036837A (en) 1973-03-23 1977-07-19 American Home Products Corporation 2 Alkoxyoxamoyl-pyrazines
US3966965A (en) 1973-03-23 1976-06-29 American Home Products Corporation Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1570494A (en) 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
US4137325A (en) 1977-03-17 1979-01-30 American Home Products Corporation Antisecretory oxamic acid esters
US4196207A (en) 1977-05-23 1980-04-01 Ici Australia Limited Process for controlling eradicating or preventing infestations of animals by Ixodid ticks
ES472163A1 (es) 1978-07-28 1979-03-16 Consejo Superior Investigacion Ÿun nuevo procedimiento para la obtencion de 5,5-dioxido de 7-amino-2h-4h-vic-triazolo (4,5-c) (1,2,6) tiadiazinaÿ
IE51802B1 (en) 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
JPS5951290A (ja) 1982-09-14 1984-03-24 Dai Ichi Seiyaku Co Ltd ベンゾチエノイミダゾピリミジンジオン化合物
ES531159A0 (es) 1984-03-30 1985-09-01 Consejo Superior Investigacion Procedimiento para la preparacion de aminociclotiadiazinas
GB8504253D0 (en) 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
US4672116A (en) 1985-12-20 1987-06-09 Ortho Pharmaceutical Corporation Substituted 5,6-dialkoxyquinazoline derivatives
JPS6387959A (ja) 1986-10-01 1988-04-19 Sanyo Kokusaku Pulp Co Ltd ステビア甘味料の呈味性改善法
US4960870A (en) 1987-02-11 1990-10-02 Ciba-Geigy Corporation Heavy metal complex azo dyes containing a benzothiophene-1,1-dioxide, 2,1-benzothiazine-2,2-dioxide, 1,4-benzothiazine-1,1-dioxide or thienopyridine-1,1-dioxide coupling component
AU617121B2 (en) * 1987-07-17 1991-11-21 Nutrasweet Company, The Substituted guanidines containing a tetrazolyl moiety and their use as high potency sweetening agents
US5380541A (en) 1987-08-07 1995-01-10 Tate & Lyle Public Limited Company Sucralose compositions
DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
JPH02238856A (ja) 1989-03-14 1990-09-21 Mitajiri Kagaku Kogyo Kk ミラクリンを有効成分とする矯味・調味料及びこれを含有する飲食品
US5192785A (en) 1989-09-03 1993-03-09 A. H. Robins Company, Incorporated Sulfamates as antiglaucoma agents
US5504095A (en) 1990-09-19 1996-04-02 Pfizer Inc. Aminobenzosultam derivatives as lipoxygenase inhibitors
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
IL102764A0 (en) 1991-08-16 1993-01-31 Merck & Co Inc Quinazoline derivatives,and pharmaceutical compositions containing them
PT100905A (pt) 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
GB9127188D0 (en) 1991-12-21 1992-02-19 Smithkline Beecham Plc Novel compounds
KR970010069B1 (ko) 1992-08-24 1997-06-20 주식회사 럭키 신규 세팔로스포린계 항생제 및 이의 제조방법
NZ304009A (en) 1995-03-14 1999-02-25 Siemens Ag Ultrasonic atomizer device with a removable precision dosating unit
IL117474A (en) 1995-03-14 2001-04-30 Siemens Ag Removable precise dosing unit containing inhaled drugs for a hearing aid device
US6046206A (en) 1995-06-07 2000-04-04 Cell Pathways, Inc. Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
DE19632423A1 (de) 1996-08-12 1998-02-19 Merck Patent Gmbh Thienopyrimidine
DK0946111T3 (da) 1996-12-20 2004-06-21 Nutrinova Gmbh Fremgangsmåde til forstærkning af sødekraften og til smagsforbedring af en blanding af højintensive sødestoffer
KR100220953B1 (ko) 1996-12-31 1999-10-01 김영환 아미드 또는 이미드를 도입한 ArF 감광막 수지
GB9711650D0 (en) 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
US5954047A (en) 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US5990117A (en) 1998-04-15 1999-11-23 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives
IL139641A0 (en) 1998-05-28 2002-02-10 Parker Hughes Inst Quinazolines for treating brain tumor
US6169118B1 (en) 1998-11-12 2001-01-02 Block Drug Company, Inc. Flavor blend for masking unpleasant taste of zinc compounds
JP2003500397A (ja) 1999-05-19 2003-01-07 スミスクライン ビーチャム パブリック リミテッド カンパニー Mrs阻害剤としての2−nh−ピリドンおよびピリミドン
GB9915995D0 (en) 1999-07-09 1999-09-08 Ahmed S Non-steroidal sulphamate compounds for use as oestrone sulphatase inhibitors
JP3523166B2 (ja) 1999-09-02 2004-04-26 高砂香料工業株式会社 食品香料劣化防止剤、食品香料劣化防止方法およびその食品香料劣化防止剤を含有する食品
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
WO2001077676A1 (en) 2000-04-07 2001-10-18 Senomyx, Inc. T2r taste receptors and genes encoding same
US6468576B1 (en) 2000-06-23 2002-10-22 Nestec S.A. Frozen slush liquid concentrate and method of making same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
EP1375487B1 (en) 2001-03-02 2011-08-24 Sumitomo Chemical Company, Limited Process for producing quinoline-3-carboxylic acid compounds
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
EP2293067B1 (en) 2001-06-26 2016-04-20 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
EP1585954B1 (en) 2001-07-03 2014-03-26 The Regents of The University of California Mammalian sweet and amino acid heterodimeric taste receptors
US20060134693A1 (en) 2001-07-06 2006-06-22 Guy Servant Olfactory cyclic nucleotide-gated channel cell-based assays to identify T1R and T2R taste modulators
DE60208908T8 (de) 2001-07-19 2008-04-10 San-Ei Gen F.F.I., Inc., Toyonaka Geschmacksverbessernde zusammensetzungen und ihre anwendung
AU2002336462A1 (en) 2001-09-06 2003-03-24 Millennium Pharmaceuticals, Inc. Piperazine and homopiperazine compounds
EP1458718B1 (en) 2001-12-14 2006-10-25 Merck Frosst Canada Ltd. Quinolinones as prostaglandin receptor ligands
WO2003055866A1 (en) 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
GB0206033D0 (en) 2002-03-14 2002-04-24 Pfizer Ltd Compounds useful in therapy
WO2004012746A2 (en) 2002-08-02 2004-02-12 The Regents Of The University Of California New uses for inhibitors of inosine monophosphate dehydrogenase
GB0230015D0 (en) 2002-12-23 2003-01-29 Novartis Ag Organic compounds
DE10324548A1 (de) 2003-05-28 2004-12-16 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Diätisches Lebensmittel bei einer gewichtskontrollierenden bzw. gewichtsreduzierenden Ernährung
SG145745A1 (en) 2003-08-06 2008-09-29 Senomyx Inc Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof
WO2005016889A1 (en) 2003-08-08 2005-02-24 Virginia Commonwealth University Compounds having antiestrogenic and tissue selective estrogenic properties
CA2558683A1 (en) 2004-03-05 2005-09-22 Sunil Srivastava High-intensity sweetener-polyol compositions
WO2005116069A2 (en) 2004-04-14 2005-12-08 Monell Chemical Senses Center Taste receptors of the t1r family from domestic dog
JP5001150B2 (ja) 2004-06-08 2012-08-15 ファミリーズ オブ スパイナル マスキュラー アトロフィー 脊髄性筋萎縮症のための2,4−ジアミノキナゾリン
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
CN101035442B (zh) * 2004-10-15 2012-04-11 味之素株式会社 甜味剂组合物
WO2006076102A2 (en) 2004-12-10 2006-07-20 The Regents Of The University Of California Fluorescent nucleoside analogs that mimic naturally occurring nucleosides
AU2005315937A1 (en) 2004-12-17 2006-06-22 F. Hoffmann-La Roche Ag Thieno-pyridine derivatives as GABA-B allosteric enhancers
WO2006084184A2 (en) 2005-02-04 2006-08-10 Senomyx, Inc. Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
ZA200707482B (en) 2005-02-04 2008-12-31 Senomyx Inc Compounds comprising linked heteroaryl moieties and their use as novel umami flavour modifiers, tastants and taste enhancers for comestible compositions
US8796441B2 (en) 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
US20080176830A1 (en) 2005-04-14 2008-07-24 Adams Nicholas D Compounds, Compositions, and Methods
CA2609186A1 (en) 2005-05-25 2006-11-30 Wyeth Methods of synthesizing substituted 3-cyanoquinolines and intermediates thereof
AR055329A1 (es) 2005-06-15 2007-08-15 Senomyx Inc Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor
JP2007007591A (ja) 2005-07-01 2007-01-18 Mikuni Corp 電解水及びその製造方法
CN101277939A (zh) 2005-09-09 2008-10-01 布里斯托尔-迈尔斯斯奎布公司 无环ikur抑制剂
JP5342878B2 (ja) 2005-10-20 2013-11-13 セノミクス・インコーポレーテッド キメラヒト甘味‐旨味および旨味‐甘味味覚受容体
US8506956B2 (en) 2005-10-31 2013-08-13 Kaneka Corporation Method for stabilizing reduced coenzyme Q10
CN101341133A (zh) 2005-12-22 2009-01-07 阿斯利康(瑞典)有限公司 喹唑啉衍生物,其制备方法及其作为抗癌药的用途
CA2656627A1 (en) 2006-07-05 2008-01-10 Merck Patent Gesellschaft Mit Beschraenkter Haftung Sulfamatobenzothiophene derivatives
WO2008024364A2 (en) * 2006-08-22 2008-02-28 Redpoint Bio Corporation Heterocyclic compounds as sweetener enhancers
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
ES2647947T3 (es) 2008-07-31 2017-12-27 Senomyx, Inc. Procesos y productos intermedios para la preparación de potenciadores del sabor dulce
CA2732098C (en) 2008-07-31 2016-11-22 Senomyx, Inc. Compositions comprising sweetness enhancers and methods of making them
PE20171345A1 (es) 2010-04-02 2017-09-13 Senomyx Inc Modificador del sabor dulce
US20130084379A1 (en) 2010-06-29 2013-04-04 Firmenich Sa Active ingredient delivery system
CN106107406B (zh) * 2010-08-12 2020-06-09 弗门尼舍公司 提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物
US8785481B2 (en) * 2010-09-29 2014-07-22 Merck Sharp & Dohme Corp. Ether benzotriazole derivatives
JP2014503473A (ja) * 2010-10-19 2014-02-13 エルセリクス セラピューティクス インコーポレイテッド 化学感覚受容体リガンドに基づく治療法
CN104603132B (zh) 2012-08-06 2020-02-21 弗门尼舍公司 甜味调节剂
EP2695899A1 (de) 2012-08-06 2014-02-12 Basf Se Polyharnstoff-Elastomere mit erhöhter Chemikalienbeständigkeit
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US9725408B2 (en) 2013-03-13 2017-08-08 Dsm Nutritional Products Ag Recovering urea and oil from a urea/oil complex

Also Published As

Publication number Publication date
KR20200001619A (ko) 2020-01-06
HK1209728A1 (en) 2016-04-08
RU2666534C2 (ru) 2018-09-11
PH12016501522B1 (en) 2017-05-22
AU2013299859B2 (en) 2017-06-15
MX2015001679A (es) 2015-06-23
CA2879554A1 (en) 2014-02-13
US20140094453A1 (en) 2014-04-03
PE20150626A1 (es) 2015-05-29
JP2019077714A (ja) 2019-05-23
JP2015530370A (ja) 2015-10-15
US20150031684A1 (en) 2015-01-29
US9420814B2 (en) 2016-08-23
CN104603132B (zh) 2020-02-21
PH12015500242A1 (en) 2015-03-30
RU2018129982A3 (es) 2022-03-30
US8877922B2 (en) 2014-11-04
IL236794B (en) 2018-07-31
PH12019500599A1 (en) 2020-03-09
JP6551936B2 (ja) 2019-07-31
EP3593648B1 (en) 2021-07-14
US20170183336A1 (en) 2017-06-29
JP6906552B2 (ja) 2021-07-21
TW201713222A (zh) 2017-04-16
SA516380399B1 (ar) 2019-08-31
SA515360005B1 (ar) 2016-06-07
CO7400867A2 (es) 2015-09-30
SG11201500880UA (en) 2015-03-30
MX354835B (es) 2018-03-21
SA515360953B1 (ar) 2018-02-22
AR092062A1 (es) 2015-03-18
BR112015002380B1 (pt) 2021-09-28
PH12015500242B1 (en) 2015-03-30
US9745293B2 (en) 2017-08-29
CN104603132A (zh) 2015-05-06
EP2880031B1 (en) 2020-06-17
PH12016501522A1 (en) 2017-05-22
US20160331013A1 (en) 2016-11-17
US20150374020A1 (en) 2015-12-31
WO2014025706A1 (en) 2014-02-13
EP2880031A1 (en) 2015-06-10
KR20200028050A (ko) 2020-03-13
TW201408222A (zh) 2014-03-01
EP3593648A1 (en) 2020-01-15
CL2015000268A1 (es) 2015-06-26
US9687015B2 (en) 2017-06-27
KR20150041040A (ko) 2015-04-15
ES2806606T3 (es) 2021-02-18
BR112015002380A2 (pt) 2017-07-04
RU2015102532A (ru) 2016-09-27
RU2018129982A (ru) 2019-03-15
TWI578915B (zh) 2017-04-21
NZ703926A (en) 2018-04-27
US9138013B2 (en) 2015-09-22
AU2013299859A1 (en) 2015-03-26
EP2880031A4 (en) 2016-02-17

Similar Documents

Publication Publication Date Title
PE20191204A1 (es) Modificador del sabor dulce
PE20160844A1 (es) Compuestos triciclicos como agentes anticancerigenos
EA201500652A1 (ru) Дифторметилникотиновые инданилкарбоксамиды
EA201390934A1 (ru) Композиции и способы модулирования fxr
EA201200018A1 (ru) Триазольные соединения, несущие серосодержащий заместитель
TN2012000575A1 (en) Compositions and methods for modulating the wnt signaling pathway
MA32257B1 (fr) Hydroxymethyl pyrrolidines comme agonistes des recepteurs beta-3- adrenergiques.
GEP20156266B (en) Spiroheterocyclic n-oxypiperidines as pesticides
PH12015500901A1 (en) Substituted tolyl fungicides
SV2010003463A (es) Compuestos organicos
PE20150352A1 (es) Moduladores del receptor de glucocorticoides de azadecalina fusionada de heteroaril-cetona
EA201100299A1 (ru) Органические соединения
EA201190235A1 (ru) Замещенные 1-цианоэтилгетероциклилкарбоксамидные соединения 750
MX2014011752A (es) Compuestos heterobiciclicos n-sustituidos y derivados para combatir plagas de animales ii.
EA201301181A1 (ru) Триазолопиридины
PE20142186A1 (es) Derivados biciclicos de pirazinona
EA201100003A1 (ru) Сульфоксиминамидные соединения для борьбы с животными-вредителями
PE20141940A1 (es) Compuestos triciclicos, composiciones que los comprenden y usos de los mismos
PE20151060A1 (es) Nuevos derivados de pirazina como agonistas del receptor cb2
MX2014011995A (es) Compuestos de furanona heterobicíclicos n-sustituidos y derivados para combatir plagas de animales.
EA201391056A1 (ru) Гетероарильные соединения в качестве лигандов 5-htрецептора
EA201500375A1 (ru) Композиция для ухода за ротовой полостью
PE20142399A1 (es) Compuestos de pirazol como inhibidores de sglt1
MX360330B (es) Regimen de administracion para nitrocatecoles.
EA201391797A1 (ru) 3-спироциклические пиперидиновые производные в качестве агонистов грелиновых рецепторов