AR092062A1 - Modificador de sabor dulce - Google Patents

Modificador de sabor dulce

Info

Publication number
AR092062A1
AR092062A1 ARP130102796A ARP130102796A AR092062A1 AR 092062 A1 AR092062 A1 AR 092062A1 AR P130102796 A ARP130102796 A AR P130102796A AR P130102796 A ARP130102796 A AR P130102796A AR 092062 A1 AR092062 A1 AR 092062A1
Authority
AR
Argentina
Prior art keywords
substituted
compounds
alkyl
carbocyclyl
heteroalkyl
Prior art date
Application number
ARP130102796A
Other languages
English (en)
Inventor
Karanewsky Donald
Werner Sara
Darmohusodo Vincent
Yamamoto Jeff
Tachdjian Catherine
Original Assignee
Senomyx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senomyx Inc filed Critical Senomyx Inc
Publication of AR092062A1 publication Critical patent/AR092062A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/56Flavouring or bittering agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52Adding ingredients
    • A23L2/60Sweeteners
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/88Taste or flavour enhancing agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/35Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15Six-membered rings
    • C07D285/16Thiadiazines; Hydrogenated thiadiazines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

La presente incluye compuestos que tienen la fórmula estructural (1), o sales o solvatos de estos. Estos compuestos son útiles como modificadores del sabor dulce. La presente también incluye composiciones que comprenden los compuestos de la presente y métodos para modular el gusto dulce de las composiciones. Reivindicación 1: Un compuesto que tiene la fórmula (1) estructural, o una sal o solvato de este, donde: A es un anillo azacíclico de cuatro a ocho miembros opcionalmente sustituido; X es un enlace covalente o -NR¹-; R¹ es hidrógeno o alquilo C₁₋₆; y, Y es alquilo, alquilo sustituido, heteroalquilo, heteroalquilo sustituido, carbociclilo, carbociclilo sustituido, heterociclilo, heterociclilo sustituido, arilo, arilo sustituido, heteroarilo, heteroarilo sustituido, aralquilo, aralquilo sustituido, heteroarilalquilo, o heteroarilalquilo sustituido; con la condición de que la fórmula (1) no incluya los compuestos del grupo de formulas (2).
ARP130102796A 2012-08-06 2013-08-06 Modificador de sabor dulce AR092062A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261679912P 2012-08-06 2012-08-06
US201361779502P 2013-03-13 2013-03-13

Publications (1)

Publication Number Publication Date
AR092062A1 true AR092062A1 (es) 2015-03-18

Family

ID=50068508

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130102796A AR092062A1 (es) 2012-08-06 2013-08-06 Modificador de sabor dulce

Country Status (23)

Country Link
US (5) US8877922B2 (es)
EP (2) EP2880031B1 (es)
JP (2) JP6551936B2 (es)
KR (3) KR20200028050A (es)
CN (1) CN104603132B (es)
AR (1) AR092062A1 (es)
AU (1) AU2013299859B2 (es)
BR (1) BR112015002380B1 (es)
CA (1) CA2879554A1 (es)
CL (1) CL2015000268A1 (es)
CO (1) CO7400867A2 (es)
ES (1) ES2806606T3 (es)
HK (1) HK1209728A1 (es)
IL (1) IL236794B (es)
MX (1) MX354835B (es)
NZ (1) NZ703926A (es)
PE (2) PE20191204A1 (es)
PH (3) PH12015500242A1 (es)
RU (2) RU2018129982A (es)
SA (3) SA515360005B1 (es)
SG (1) SG11201500880UA (es)
TW (2) TWI578915B (es)
WO (1) WO2014025706A1 (es)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3208272B1 (en) * 2005-11-08 2020-01-08 Vertex Pharmaceuticals Incorporated Heterocyclic modulators of atp-binding cassette transporters
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
CA2731800C (en) 2008-07-31 2018-03-20 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
US9000054B2 (en) 2010-08-12 2015-04-07 Senomyx, Inc. Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
MX354835B (es) * 2012-08-06 2018-03-21 Senomyx Inc Modificador del sabor dulce.
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US20140272068A1 (en) * 2013-03-14 2014-09-18 Indra Prakash Beverages containing rare sugars
MX369091B (es) * 2014-05-09 2019-10-29 Firmenich & Cie Solubilizacion de modulador y sabor dulce.
WO2016040577A1 (en) 2014-09-11 2016-03-17 Pepsico, Inc. Sweetness enhancer
BR112018008710B1 (pt) 2015-10-29 2022-04-12 Firmenich Incorporated Adoçantes de alta intensidade
EP3439488B1 (en) 2016-04-06 2020-12-02 The Coca-Cola Company Sweetness and taste improvement of steviol glycoside or mogroside sweeteners
US10494397B2 (en) 2016-07-15 2019-12-03 Pepsico, Inc. Rebaudioside analogs
US10966447B2 (en) 2016-07-19 2021-04-06 Pepsico, Inc. Glucosyringic acid analogs as sweetness profile modifiers
US10085472B2 (en) 2016-08-29 2018-10-02 Pepsico, Inc. Compositions comprising rebaudioside J
HUE047858T2 (hu) 2016-09-21 2020-05-28 Celanese Int Corp Aceszulfám-kálium kompozíciók és eljárás ezek elõállítására
EP3319949B1 (en) 2016-09-21 2020-07-22 Celanese International Corporation Acesulfame potassium compositions and processes for producing same
PL3319948T3 (pl) 2016-09-21 2021-12-27 Celanese International Corporation Kompozycje acesulfamu potasowego i sposoby ich wytwarzania
US10030000B2 (en) 2016-09-21 2018-07-24 Celanese International Corporation Acesulfame potassium compositions and processes for producing same
US11060124B2 (en) 2017-05-03 2021-07-13 Firmenich Incorporated Methods for making high intensity sweeteners
BR112020006674A2 (pt) 2017-10-06 2020-10-06 Cargill, Incorporated composição de glicosídeo de esteviol prontamente dissolvível, e, composição seca de glicosídeo de esteviol prontamente dissolvível
US11019837B2 (en) 2017-11-08 2021-06-01 Pepsico, Inc. Mouthfeel modulation in reduced and sugar-free beverages using a blend of pectin and xanthan gum
US10806165B2 (en) 2018-04-24 2020-10-20 Stokely-Van Camp, Inc. Ready-to-drink plant protein beverage product and methods for making same
US11700869B2 (en) 2018-06-27 2023-07-18 Pepsico, Inc. Mouthfeel enhancing composition
MX2021001193A (es) 2018-08-07 2021-04-28 Firmenich Incorporated 2,2-dioxidos de 4-amino-1h-benzo[c][1,2,6]tiadiazina 5-sustituidos y formulaciones y usos de los mismos.
JP2022524901A (ja) 2019-03-28 2022-05-11 フイルメニツヒ ソシエテ アノニム フレーバーシステム
WO2020200916A1 (en) 2019-04-04 2020-10-08 Firmenich Sa Mogroside compounds and uses thereof
BR112021019811A2 (pt) 2019-04-06 2021-12-07 Cargill Inc Composição de glicosídeo de esteviol, bebida, métodos para reduzir um atributo sensorial indesejável de uma solução aquosa de glicosídeo de esteviol, para reduzir a persistência de doçura de um componente de glicosídeo de esteviol em uma composição comestível e para reduzir o amargor de um componente de glicosídeo de esteviol em uma composição comestível, e, soluções aquosa de glicosídeo de esteviol com reduzida persistência de doçura e aquosa de glicosídeo de esteviol com reduzido amargor
BR112021014587A2 (pt) 2019-06-28 2022-01-04 Firmenich & Cie Misturas de gordura, emulsões das mesmas e usos relacionados
CN114364265A (zh) 2019-09-05 2022-04-15 弗门尼舍有限公司 黄烷酮衍生物及其作为甜味增强剂的用途
WO2021089501A1 (en) * 2019-11-06 2021-05-14 Dsm Ip Assets B.V. Novel method
CN113226058A (zh) 2019-11-11 2021-08-06 弗门尼舍有限公司 姜酚化合物及其作为风味改良剂的用途
US20230028760A1 (en) 2019-12-13 2023-01-26 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2021119035A1 (en) 2019-12-13 2021-06-17 Firmenich Incorporated Taste modifying compositions and uses thereof
US20230000122A1 (en) 2019-12-18 2023-01-05 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2021126570A1 (en) 2019-12-18 2021-06-24 Firmenich Incorporated Taste modifying compositions and uses thereof
EP4048086A1 (en) 2020-03-05 2022-08-31 Firmenich SA 11-oxo-cucurbitanes and their use as flavor modifiers
WO2021198199A1 (en) 2020-03-31 2021-10-07 Firmenich Sa Flavor composition
EP4055006A1 (en) 2020-04-17 2022-09-14 Firmenich SA Amino acid derivatives and their use as flavor modifiers
WO2021233973A1 (en) 2020-05-22 2021-11-25 Firmenich Sa Compositions for reducing salty taste and uses thereof
BR112022016411A2 (pt) 2020-06-03 2022-10-11 Firmenich & Cie Composições para reduzir gostos desagradáveis e usos das mesmas
MX2022015148A (es) 2020-06-24 2023-01-11 Firmenich & Cie Composiciones edulcorantes y usos de las mismas.
WO2022013163A1 (en) 2020-07-14 2022-01-20 Firmenich Sa Reduction of undesirable taste notes in oral care products
CA3188905A1 (en) 2020-07-24 2022-01-27 Firmenich Incorporated Savory taste enhancement via transmembrane region binding
JP2023541748A (ja) 2020-09-22 2023-10-04 フイルメニツヒ ソシエテ アノニム サリチル酸メチル不含のウィンターグリーンフレーバー組成物
US20230329299A1 (en) 2020-10-13 2023-10-19 Firmenich Sa Malonyl steviol glycosides and their comestible use
US20230345986A1 (en) 2020-10-27 2023-11-02 Firmenich Sa Conjugated diynes and their use as flavor modifiers
WO2022115837A1 (en) 2020-11-24 2022-06-02 Firmenich Incorporated Kokumi taste enhancement and related screening methods
EP4175490A1 (en) 2020-11-29 2023-05-10 Firmenich SA Compositions that reduce peroxide off taste and uses thereof
US20230397627A1 (en) 2020-12-23 2023-12-14 Firmenich Sa Uses of fat blends and emulsions thereof
JP2024502612A (ja) 2021-01-07 2024-01-22 コナゲン インコーポレイテッド 甘味料の甘味を増強するための化合物及び方法
WO2022155054A1 (en) 2021-01-13 2022-07-21 Firmenich Incorporated Compositions that enhance the cooling effect
WO2022155668A1 (en) 2021-01-15 2022-07-21 Firmenich Incorporated Sweetener compostions comprising siamenoside i and uses thereof
CN117098460A (zh) 2021-01-15 2023-11-21 弗门尼舍公司 包含罗汉果苷的甜味剂组合物及其用途
WO2022171569A1 (en) 2021-02-10 2022-08-18 Firmenich Sa Fiber blends, sweetened fiber blends, and their comestible use
JP2024509300A (ja) 2021-03-09 2024-02-29 フイルメニツヒ ソシエテ アノニム ヒドロキシおよびメトキシ置換フラボンならびにそれらの使用
US20240099344A1 (en) 2021-03-09 2024-03-28 Firmenich Sa Hydroxy- and methoxy-substituted flavonoids and their use
EP4277474A1 (en) 2021-04-06 2023-11-22 Firmenich SA Use of gingerdiol compounds to enhance flavor
WO2022231918A1 (en) 2021-04-26 2022-11-03 Firmenich Incorporated Amide compounds and their use as flavor modifiers
US20240156140A1 (en) 2021-04-26 2024-05-16 Firmenich Incorporated Amide compounds and their use as flavor modifiers
EP4307919A2 (en) 2021-05-11 2024-01-24 Firmenich SA Process of making gingerol compounds and their use as flavor modifiers
EP4307910A1 (en) 2021-05-24 2024-01-24 Firmenich SA Flavored fiber blends and their comestible use
EP4304385A1 (en) 2021-05-28 2024-01-17 Firmenich Incorporated Compositions that enhance the cooling effect
BR112023022013A2 (pt) 2021-06-02 2023-12-26 Firmenich & Cie Processo de desacetilação, composições e usos das mesmas
EP4329499A1 (en) 2021-06-23 2024-03-06 Firmenich SA Flavor-modifying compositions containing lactase
WO2023278394A1 (en) 2021-06-28 2023-01-05 Firmenich Incorporated Polycationic salts of phenolic compounds and uses thereof
EP4362704A1 (en) 2021-06-29 2024-05-08 Firmenich SA Licorice compounds and their use as flavor modifiers
EP4333645A1 (en) 2021-06-29 2024-03-13 Firmenich Incorporated Mogroside compounds and their comestible use
WO2023046914A1 (en) 2021-09-27 2023-03-30 Firmenich Sa Flavor compositions containing iron compounds and their use
KR20240063912A (ko) 2021-09-27 2024-05-10 피르메니히 인코포레이티드 증류주의 풍미를 변화시키기 위한 바닐릴 에테르의 용도
EP4384027A1 (en) 2021-11-01 2024-06-19 Firmenich SA Composition comprising a nutrient and a taste modulator
CN118251134A (zh) 2021-11-16 2024-06-25 弗门尼舍公司 酰胺化合物及其作为风味修饰剂的用途
WO2023107904A1 (en) 2021-12-07 2023-06-15 Firmenich Incorporated Reduction of bitter taste of plant proteins and related assays and screening methods
WO2023118002A1 (en) 2021-12-20 2023-06-29 Firmenich Sa Encapsulated metal compounds and comestible uses thereof
WO2023117643A1 (en) 2021-12-23 2023-06-29 Firmenich Sa Antimicrobial composition having encapsulated colorant
WO2023165764A1 (en) 2022-03-04 2023-09-07 Firmenich Sa Purification process for polymethoxylated flavonoids and compositions obtained therefrom
WO2023172415A1 (en) 2022-03-07 2023-09-14 Firmenich Incorporated Sweetener compositions
WO2023169995A1 (en) 2022-03-10 2023-09-14 Firmenich Sa Sweetener compositions
WO2023172372A1 (en) 2022-03-11 2023-09-14 Firmenich Incorporated Amide compounds and their use as flavor modifiers
WO2023172394A1 (en) 2022-03-11 2023-09-14 Firmenich Incorporated Flavanone compounds and their use as flavor modifiers
WO2023180063A1 (en) 2022-03-25 2023-09-28 Firmenich Sa Fatty acid amides and their use as flavor modifiers
WO2023186792A1 (en) 2022-03-28 2023-10-05 Firmenich Sa Non-animal protein compositions and uses thereof
WO2023196128A1 (en) 2022-04-06 2023-10-12 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2023198436A2 (en) 2022-04-11 2023-10-19 Firmenich Sa Sweetener compositions
WO2023224814A1 (en) 2022-05-16 2023-11-23 Firmenich Incorporated Saturated fatty acids and their use to modify taste
WO2023224812A1 (en) 2022-05-16 2023-11-23 Firmenich Incorporated Unsaturated fatty acids and their use to modify taste
WO2023232968A1 (en) 2022-06-03 2023-12-07 Firmenich Sa Fat reduction in non-animal protein compositions
WO2023242177A1 (en) 2022-06-14 2023-12-21 Firmenich Sa Polyelectrolyte complexes of proteins and uses thereof
WO2023247332A1 (en) 2022-06-24 2023-12-28 Firmenich Sa Taste modifying compositions and uses thereof
WO2024011086A1 (en) 2022-07-07 2024-01-11 Firmenich Incorporated Compositions that enhance the cooling effect
WO2024041974A1 (en) 2022-08-22 2024-02-29 Firmenich Sa Gel compositions and their use in seafood analogue products
WO2024089025A1 (en) 2022-10-26 2024-05-02 Firmenich Sa Extrusion methods and flavored products formed thereby
WO2024091457A1 (en) 2022-10-26 2024-05-02 Firmenich Incorporated Taste modifying compositions and uses thereof
WO2024094523A1 (en) 2022-11-01 2024-05-10 Firmenich Sa Low-calorie composition for flavor modification

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB951651A (en) 1960-02-17 1964-03-11 Shell Res Ltd Substituted benzonitriles, their preparation and compositions containing them
US3278532A (en) 1964-07-06 1966-10-11 Sandoz Ag Dioxybenzothiadiazines
US3857972A (en) 1971-03-10 1974-12-31 Int Flavors & Fragrances Inc Flavoring with an oxocyclic pyrimidine
US3843804A (en) 1971-03-10 1974-10-22 Int Flavors & Fragrances Inc Novel flavoring compositions and processes
LU64388A1 (es) 1971-12-02 1973-07-16
FI54312C (fi) 1972-05-09 1978-11-10 Sumitomo Chemical Co Foerfarande foer framstaellning av tieno-(2,3-d)pyrimidinderivat med avsoendring av urinsyra i urin utoekande
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3960860A (en) 1973-01-08 1976-06-01 International Flavors & Fragrances Inc. 2-Methyl-5,7-dihydrothieno-[3,4d]-pyrimidine
US3966965A (en) 1973-03-23 1976-06-29 American Home Products Corporation Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions
US4036837A (en) 1973-03-23 1977-07-19 American Home Products Corporation 2 Alkoxyoxamoyl-pyrazines
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
GB1570494A (en) 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
US4137325A (en) 1977-03-17 1979-01-30 American Home Products Corporation Antisecretory oxamic acid esters
US4196207A (en) 1977-05-23 1980-04-01 Ici Australia Limited Process for controlling eradicating or preventing infestations of animals by Ixodid ticks
ES472163A1 (es) 1978-07-28 1979-03-16 Consejo Superior Investigacion Ÿun nuevo procedimiento para la obtencion de 5,5-dioxido de 7-amino-2h-4h-vic-triazolo (4,5-c) (1,2,6) tiadiazinaÿ
IE51802B1 (en) 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
JPS5951290A (ja) 1982-09-14 1984-03-24 Dai Ichi Seiyaku Co Ltd ベンゾチエノイミダゾピリミジンジオン化合物
ES8507558A1 (es) 1984-03-30 1985-09-01 Consejo Superior Investigacion Procedimiento para la preparacion de aminociclotiadiazinas
GB8504253D0 (en) 1985-02-19 1985-03-20 Ici Plc Electrostatic spraying apparatus
US4672116A (en) 1985-12-20 1987-06-09 Ortho Pharmaceutical Corporation Substituted 5,6-dialkoxyquinazoline derivatives
JPS6387959A (ja) 1986-10-01 1988-04-19 Sanyo Kokusaku Pulp Co Ltd ステビア甘味料の呈味性改善法
US4960870A (en) 1987-02-11 1990-10-02 Ciba-Geigy Corporation Heavy metal complex azo dyes containing a benzothiophene-1,1-dioxide, 2,1-benzothiazine-2,2-dioxide, 1,4-benzothiazine-1,1-dioxide or thienopyridine-1,1-dioxide coupling component
JPH0655730B2 (ja) 1987-07-17 1994-07-27 ザ ヌトラスウィート カンパニー 強力甘味剤
US5380541A (en) 1987-08-07 1995-01-10 Tate & Lyle Public Limited Company Sucralose compositions
DE3815221C2 (de) 1988-05-04 1995-06-29 Gradinger F Hermes Pharma Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen
JPH02238856A (ja) 1989-03-14 1990-09-21 Mitajiri Kagaku Kogyo Kk ミラクリンを有効成分とする矯味・調味料及びこれを含有する飲食品
US5192785A (en) 1989-09-03 1993-03-09 A. H. Robins Company, Incorporated Sulfamates as antiglaucoma agents
US5504095A (en) 1990-09-19 1996-04-02 Pfizer Inc. Aminobenzosultam derivatives as lipoxygenase inhibitors
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
IL102764A0 (en) 1991-08-16 1993-01-31 Merck & Co Inc Quinazoline derivatives,and pharmaceutical compositions containing them
PT100905A (pt) 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
GB9127188D0 (en) 1991-12-21 1992-02-19 Smithkline Beecham Plc Novel compounds
KR970010069B1 (ko) 1992-08-24 1997-06-20 주식회사 럭키 신규 세팔로스포린계 항생제 및 이의 제조방법
IL117474A (en) 1995-03-14 2001-04-30 Siemens Ag Removable precise dosing unit containing inhaled drugs for a hearing aid device
IL117473A (en) 1995-03-14 2001-08-26 Siemens Ag Ultrasonic atomizer device with removable precision dosating unit
US6046206A (en) 1995-06-07 2000-04-04 Cell Pathways, Inc. Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
DE19632423A1 (de) 1996-08-12 1998-02-19 Merck Patent Gmbh Thienopyrimidine
ES2212816T3 (es) 1996-12-20 2004-08-01 NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH Procedimiento para el refuerzo del poder edulcorante y para el mejoramiento del sabor de una mezcla de materiales edulcorantes muy intensos.
KR100220953B1 (ko) 1996-12-31 1999-10-01 김영환 아미드 또는 이미드를 도입한 ArF 감광막 수지
GB9711650D0 (en) 1997-06-05 1997-07-30 Pfizer Ltd Compounds useful in therapy
NZ504021A (en) 1997-10-17 2003-04-29 Systemic Pulmonary Delivery Lt Method and apparatus for delivering aerosolized medication having air discharged through air tube directly into plume of aerosolized medication
US5990117A (en) 1998-04-15 1999-11-23 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives
EP1082311A1 (en) 1998-05-28 2001-03-14 Parker Hughes Institute Quinazolines for treating brain tumor
US6169118B1 (en) 1998-11-12 2001-01-02 Block Drug Company, Inc. Flavor blend for masking unpleasant taste of zinc compounds
AU5213300A (en) 1999-05-19 2000-12-12 Smithkline Beecham Plc 2-nh-pyridones and pyrimidones as mrs inhibitors
GB9915995D0 (en) 1999-07-09 1999-09-08 Ahmed S Non-steroidal sulphamate compounds for use as oestrone sulphatase inhibitors
JP3523166B2 (ja) 1999-09-02 2004-04-26 高砂香料工業株式会社 食品香料劣化防止剤、食品香料劣化防止方法およびその食品香料劣化防止剤を含有する食品
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
WO2001077676A1 (en) 2000-04-07 2001-10-18 Senomyx, Inc. T2r taste receptors and genes encoding same
US6468576B1 (en) 2000-06-23 2002-10-22 Nestec S.A. Frozen slush liquid concentrate and method of making same
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US6852862B2 (en) 2001-03-02 2005-02-08 Sumika Fine Chemicals Co., Ltd. Process for producing quinoline-3-carboxylic acid compound
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
AU2002326315B2 (en) 2001-06-26 2007-07-05 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
CA2452716C (en) 2001-07-03 2012-06-26 The Regents Of The University Of California Mammalian sweet and amino acid heterodimeric taste receptors
US20060134693A1 (en) 2001-07-06 2006-06-22 Guy Servant Olfactory cyclic nucleotide-gated channel cell-based assays to identify T1R and T2R taste modulators
EP1415545B1 (en) 2001-07-19 2006-01-25 San-Ei Gen F.F.I., Inc. Flavor-improving compositions and application thereof
WO2003022214A2 (en) 2001-09-06 2003-03-20 Millennium Pharmaceuticals, Inc. Piperazine and homopiperazine compounds
DE60215699T2 (de) 2001-12-14 2007-08-30 Merck Frosst Canada Ltd., Kirkland Quinolinone als prostaglandin rezeptor liganden
WO2003055866A1 (en) 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation Quinazoline and quinoline derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
GB0206033D0 (en) 2002-03-14 2002-04-24 Pfizer Ltd Compounds useful in therapy
AU2003261354A1 (en) 2002-08-02 2004-02-23 The Regents Of The University Of California New uses for inhibitors of inosine monophosphate dehydrogenase
GB0230015D0 (en) 2002-12-23 2003-01-29 Novartis Ag Organic compounds
DE10324548A1 (de) 2003-05-28 2004-12-16 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Diätisches Lebensmittel bei einer gewichtskontrollierenden bzw. gewichtsreduzierenden Ernährung
BRPI0413347A (pt) 2003-08-06 2006-10-10 Senomyx Inc novos sabores, modificadores de sabor, agentes de sabor, realçadores de sabor, agentes de sabor e/ou realçadores umami ou doces, e utilização correspondente
WO2005016889A1 (en) 2003-08-08 2005-02-24 Virginia Commonwealth University Compounds having antiestrogenic and tissue selective estrogenic properties
WO2005087020A1 (en) 2004-03-05 2005-09-22 Richmond Chemical Corporation High-intensity sweetener-polyol compositions
US7541158B2 (en) 2004-04-14 2009-06-02 Monell Chemical Senses Center Taste receptors of the T1R family from domestic dog
CA2569763C (en) 2004-06-08 2013-03-12 Decode Chemistry, Inc. 2,4-diaminoquinazolines for spinal muscular atrophy
US20060045953A1 (en) 2004-08-06 2006-03-02 Catherine Tachdjian Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers
US20060083695A1 (en) 2004-10-15 2006-04-20 Ajinomoto Co. Inc Sweetener composition
WO2006076102A2 (en) 2004-12-10 2006-07-20 The Regents Of The University Of California Fluorescent nucleoside analogs that mimic naturally occurring nucleosides
BRPI0519521A2 (pt) 2004-12-17 2009-02-10 Hoffmann La Roche derivados de tieno-piridina como aumentadores alostÉricos gaba-b
WO2006084184A2 (en) 2005-02-04 2006-08-10 Senomyx, Inc. Molecules comprising linked organic moieties as flavor modifiers for comestible compositions
EP1850681B1 (en) 2005-02-04 2019-12-18 Firmenich Incorporated Compounds comprising linked hetero aryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions
US8796441B2 (en) 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
WO2006113432A2 (en) 2005-04-14 2006-10-26 Smithkline Beecham Corporation Compounds, compositions and methods
EP1883631A1 (en) 2005-05-25 2008-02-06 Wyeth Methods of synthesizing substituted 3-cyanoquinolines and intermediates thereof
TW200715993A (en) 2005-06-15 2007-05-01 Senomyx Inc Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers
JP2007007591A (ja) 2005-07-01 2007-01-18 Mikuni Corp 電解水及びその製造方法
EP1922311A2 (en) 2005-09-09 2008-05-21 Brystol-Myers Squibb Company Acyclic ikur inhibitors
ES2658859T3 (es) 2005-10-20 2018-03-12 Senomyx, Inc. Receptores del sabor dulce-umami y umami-dulce humanos quiméricos
US8506956B2 (en) 2005-10-31 2013-08-13 Kaneka Corporation Method for stabilizing reduced coenzyme Q10
WO2007071963A2 (en) 2005-12-22 2007-06-28 Astrazeneca Ab Quinazoline derivatives, process for their preparation and their use as anti-cancer agents
CA2656627A1 (en) 2006-07-05 2008-01-10 Merck Patent Gesellschaft Mit Beschraenkter Haftung Sulfamatobenzothiophene derivatives
KR20090053795A (ko) 2006-08-22 2009-05-27 레드포인트 바이오 코포레이션 감미료 증강제로서의 헤테로환 화합물
US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US8633186B2 (en) 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
CA2731800C (en) 2008-07-31 2018-03-20 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
WO2010014813A2 (en) 2008-07-31 2010-02-04 Senomyx, Inc. Compositions comrpising sweetness enhancers and methods of making them
RU2605549C2 (ru) * 2010-04-02 2016-12-20 Синомикс, Инк. Производные 3-карбокси-4-аминохинолина, полезные как модификаторы сладкого вкуса
US20130084379A1 (en) 2010-06-29 2013-04-04 Firmenich Sa Active ingredient delivery system
US9000054B2 (en) * 2010-08-12 2015-04-07 Senomyx, Inc. Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
US8785481B2 (en) * 2010-09-29 2014-07-22 Merck Sharp & Dohme Corp. Ether benzotriazole derivatives
US20130338095A1 (en) * 2010-10-19 2013-12-19 Elcelyx Therapeutics, Inc. Chemosensory Receptor Ligand-Based Therapies
EP2695899A1 (de) 2012-08-06 2014-02-12 Basf Se Polyharnstoff-Elastomere mit erhöhter Chemikalienbeständigkeit
MX354835B (es) 2012-08-06 2018-03-21 Senomyx Inc Modificador del sabor dulce.
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
EP2970820B1 (en) 2013-03-13 2023-03-29 DSM Nutritional Products AG Recovering urea and oil from a urea/oil complex

Also Published As

Publication number Publication date
KR20200001619A (ko) 2020-01-06
WO2014025706A1 (en) 2014-02-13
ES2806606T3 (es) 2021-02-18
CO7400867A2 (es) 2015-09-30
US9138013B2 (en) 2015-09-22
SG11201500880UA (en) 2015-03-30
EP3593648B1 (en) 2021-07-14
RU2015102532A (ru) 2016-09-27
TW201713222A (zh) 2017-04-16
US20170183336A1 (en) 2017-06-29
US20150374020A1 (en) 2015-12-31
PE20191204A1 (es) 2019-09-10
US20150031684A1 (en) 2015-01-29
US9745293B2 (en) 2017-08-29
JP2015530370A (ja) 2015-10-15
JP6906552B2 (ja) 2021-07-21
CN104603132B (zh) 2020-02-21
US9687015B2 (en) 2017-06-27
MX2015001679A (es) 2015-06-23
CN104603132A (zh) 2015-05-06
PH12016501522A1 (en) 2017-05-22
RU2666534C2 (ru) 2018-09-11
EP2880031B1 (en) 2020-06-17
MX354835B (es) 2018-03-21
TW201408222A (zh) 2014-03-01
CL2015000268A1 (es) 2015-06-26
AU2013299859A1 (en) 2015-03-26
JP2019077714A (ja) 2019-05-23
NZ703926A (en) 2018-04-27
IL236794B (en) 2018-07-31
BR112015002380A2 (pt) 2017-07-04
RU2018129982A3 (es) 2022-03-30
EP2880031A4 (en) 2016-02-17
US20140094453A1 (en) 2014-04-03
SA516380399B1 (ar) 2019-08-31
CA2879554A1 (en) 2014-02-13
KR20150041040A (ko) 2015-04-15
PH12015500242B1 (en) 2015-03-30
US20160331013A1 (en) 2016-11-17
KR20200028050A (ko) 2020-03-13
TWI578915B (zh) 2017-04-21
BR112015002380B1 (pt) 2021-09-28
PH12015500242A1 (en) 2015-03-30
EP3593648A1 (en) 2020-01-15
SA515360953B1 (ar) 2018-02-22
HK1209728A1 (en) 2016-04-08
SA515360005B1 (ar) 2016-06-07
RU2018129982A (ru) 2019-03-15
AU2013299859B2 (en) 2017-06-15
US9420814B2 (en) 2016-08-23
JP6551936B2 (ja) 2019-07-31
EP2880031A1 (en) 2015-06-10
US8877922B2 (en) 2014-11-04
PH12019500599A1 (en) 2020-03-09
PH12016501522B1 (en) 2017-05-22
PE20150626A1 (es) 2015-05-29

Similar Documents

Publication Publication Date Title
AR092062A1 (es) Modificador de sabor dulce
EA201691085A1 (ru) Замещенные бензамиды и способы их применения
CY1119422T1 (el) Παραγωγα μπετουλινης
CR20170118A (es) Derivados espirodiamina como inhibidores de la aldosterona sintasa
CO2017001178A2 (es) Derivado de piridona que tiene un grupo tetrahidropiranil metilo
EA201691272A1 (ru) Тетрагидропиридопиразины в качестве модуляторов gpr6
EA201692114A1 (ru) Замещенные дигидроизохинолиноновые соединения
AR077695A1 (es) Derivados de pirimidina como inhibidores del factor ixa
CO2017008600A2 (es) Análogos de desacetoxitubulisina h, composiciones y método de producción de los mismos
EA201591451A1 (ru) Модуляторы flap
CY1117912T1 (el) Ενωσεις πυραζολιου ως αναστολεiς του συμμεταφορεα νατριου-γλυκοζης 1 (sglt1)
DOP2014000178A (es) Nuevos derivados de bencil sulfonamida útiles como inhibidores de mogat-2
EA201691141A1 (ru) Соединения против ccr6
CY1118514T1 (el) Μεθοδος για την παρασκευη πεμετρεξιδης και αλατος λυσινης αυτης
EA201792425A1 (ru) Трициклические соединения и их применение в качестве ингибиторов фосфодиэстераз
EA201491195A1 (ru) Способ получения композиции, содержащей галактоолигосахариды
CU20170007A7 (es) Compuestos de imidazopiridazina
EA201891770A1 (ru) Малеатная соль агониста tlr7, ее кристаллические формы c, d и e, способы получения и применение малеатной соли и кристаллических форм
TW201613603A (en) Pharmaceutical preparation
EA201600619A1 (ru) Хромен и 1,1а, 2,7в-тетрагидроциклопропа[с]хромен пиридопиразиндионы в качестве модулятора гамма-секретазы
ES2721623T3 (es) Procedimiento novedoso para la preparación de ceftarolina fosamil
EA201692288A1 (ru) Способ получения фосфорсодержащих циангидринов
CY1119111T1 (el) Trpv1 ανταγωνιστες συμπεριλαμβανομενου διυδροξυ υποκαταστατη και χρησεις αυτων
EA201600394A1 (ru) Трициклические соединения пиперидина
DOP2016000293A (es) Derivados de diheterociclo enlazado a cicloalquilo

Legal Events

Date Code Title Description
FB Suspension of granting procedure