|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US4554101A
(en)
|
1981-01-09 |
1985-11-19 |
New York Blood Center, Inc. |
Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
|
|
CH660375A5
(it)
|
1983-02-08 |
1987-04-15 |
Sclavo Spa |
Procedimento per la produzione di proteine correlate alla tossina difterica.
|
|
US4708871A
(en)
|
1983-03-08 |
1987-11-24 |
Commonwealth Serum Laboratories Commission |
Antigenically active amino acid sequences
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
US4650764A
(en)
|
1983-04-12 |
1987-03-17 |
Wisconsin Alumni Research Foundation |
Helper cell
|
|
JPS6147500A
(ja)
|
1984-08-15 |
1986-03-07 |
Res Dev Corp Of Japan |
キメラモノクロ−ナル抗体及びその製造法
|
|
EP0173494A3
(en)
|
1984-08-27 |
1987-11-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Chimeric receptors by dna splicing and expression
|
|
GB8422238D0
(en)
|
1984-09-03 |
1984-10-10 |
Neuberger M S |
Chimeric proteins
|
|
GB8424757D0
(en)
|
1984-10-01 |
1984-11-07 |
Pasteur Institut |
Retroviral vector
|
|
SE8405493D0
(sv)
|
1984-11-01 |
1984-11-01 |
Bror Morein |
Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
|
|
FR2573436B1
(fr)
|
1984-11-20 |
1989-02-17 |
Pasteur Institut |
Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins
|
|
JPS61134325A
(ja)
|
1984-12-04 |
1986-06-21 |
Teijin Ltd |
ハイブリツド抗体遺伝子の発現方法
|
|
US4797368A
(en)
|
1985-03-15 |
1989-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adeno-associated virus as eukaryotic expression vector
|
|
US4666829A
(en)
|
1985-05-15 |
1987-05-19 |
University Of California |
Polypeptide marker for Alzheimer's disease and its use for diagnosis
|
|
EP0232262A4
(en)
|
1985-08-15 |
1989-09-19 |
Stauffer Chemical Co |
TRYPTOPHANE GENERATING MICROORGANISM.
|
|
US5078996A
(en)
|
1985-08-16 |
1992-01-07 |
Immunex Corporation |
Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
|
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
JPS63501765A
(ja)
|
1985-11-01 |
1988-07-21 |
インタ−ナショナル、ジェネティック、エンジニアリング インコ−ポレ−テッド |
抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途
|
|
US4861719A
(en)
|
1986-04-25 |
1989-08-29 |
Fred Hutchinson Cancer Research Center |
DNA constructs for retrovirus packaging cell lines
|
|
US5514581A
(en)
|
1986-11-04 |
1996-05-07 |
Protein Polymer Technologies, Inc. |
Functional recombinantly prepared synthetic protein polymer
|
|
US4980289A
(en)
|
1987-04-27 |
1990-12-25 |
Wisconsin Alumni Research Foundation |
Promoter deficient retroviral vector
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
JPH01125328A
(ja)
|
1987-07-30 |
1989-05-17 |
Centro Natl De Biopreparados |
髄膜炎菌ワクチン
|
|
CA1315719C
(en)
|
1988-02-05 |
1993-04-06 |
Arthur Bank |
Retroviral packaging cell lines and processes of using same
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
CA1339354C
(en)
|
1988-09-01 |
1997-08-26 |
The Whitehead Institute For Biomedical Research |
Recombinant retroviruses with amphotropic and ecotropic host ranges
|
|
US7118757B1
(en)
|
1988-12-19 |
2006-10-10 |
Wyeth Holdings Corporation |
Meningococcal class 1 outer-membrane protein vaccine
|
|
US5124263A
(en)
|
1989-01-12 |
1992-06-23 |
Wisconsin Alumni Research Foundation |
Recombination resistant retroviral helper cell and products produced thereby
|
|
DE69033600T2
(de)
|
1989-03-09 |
2001-04-05 |
American Cyanamid Co., Madison |
Verfahren zur Isolierung von Haemopnilus influenzae Protein-E
|
|
US5354844A
(en)
|
1989-03-16 |
1994-10-11 |
Boehringer Ingelheim International Gmbh |
Protein-polycation conjugates
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
HU212924B
(en)
|
1989-05-25 |
1996-12-30 |
Chiron Corp |
Adjuvant formulation comprising a submicron oil droplet emulsion
|
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
CA2039921A1
(en)
|
1990-04-16 |
1991-10-17 |
Xandra O. Breakefield |
Transfer and expression of gene sequences into central nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
WO1991018088A1
(en)
|
1990-05-23 |
1991-11-28 |
The United States Of America, Represented By The Secretary, United States Department Of Commerce |
Adeno-associated virus (aav)-based eucaryotic vectors
|
|
IE912559A1
(en)
|
1990-07-19 |
1992-01-29 |
Merck & Co Inc |
The class ii protein of the outer membrane of neisseria¹meningitidis, and vaccines containing same
|
|
WO1992005263A1
(en)
|
1990-09-25 |
1992-04-02 |
Cantab Pharmaceuticals Research Limited |
Viral defective vaccine produced by transcomplementing cell line
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
IL101715A
(en)
|
1991-05-02 |
2005-06-19 |
Amgen Inc |
Recombinant dna-derived cholera toxin subunit analogs
|
|
WO1993007897A1
(en)
|
1991-10-21 |
1993-04-29 |
Medimmune, Inc. |
Bacterial expression vectors containing dna encoding secretion signals of lipoproteins
|
|
US5252479A
(en)
|
1991-11-08 |
1993-10-12 |
Research Corporation Technologies, Inc. |
Safe vector for gene therapy
|
|
IT1253009B
(it)
|
1991-12-31 |
1995-07-10 |
Sclavo Ricerca S R L |
Mutanti immunogenici detossificati della tossina colerica e della tossina lt, loro preparazione ed uso per la preparazione di vaccini
|
|
WO1993015115A1
(en)
|
1992-01-24 |
1993-08-05 |
Cornell Research Foundation, Inc. |
E. coli dna polymerase iii holoenzyme and subunits
|
|
AU680459B2
(en)
|
1992-12-03 |
1997-07-31 |
Genzyme Corporation |
Gene therapy for cystic fibrosis
|
|
DK0616034T3
(da)
|
1993-03-05 |
2005-02-21 |
Wyeth Corp |
Plasmid til fremstilling af CRM-protein og diphtheria toxin
|
|
EP0689603A1
(en)
|
1993-03-19 |
1996-01-03 |
Cantab Pharmaceuticals Research Limited |
Defective mutant non-retroviral virus (e.g. hsv) as vaccine
|
|
DK0624376T3
(da)
|
1993-05-13 |
2000-07-24 |
American Cyanamid Co |
Fremstilling og anvendelse af LOS-udtømte ydre membranproteiner af gram-negative cocci
|
|
FR2705361B1
(fr)
|
1993-05-18 |
1995-08-04 |
Centre Nat Rech Scient |
Vecteurs viraux et utilisation en thérapie génique.
|
|
FR2705686B1
(fr)
|
1993-05-28 |
1995-08-18 |
Transgene Sa |
Nouveaux adénovirus défectifs et lignées de complémentation correspondantes.
|
|
BR9405507A
(pt)
|
1993-07-13 |
1999-05-25 |
Rhone Poulenc Rorer Sa |
Adenovirus recombinante defeituoso linhagem celular e composição farmaceutica
|
|
CA2168202A1
(en)
|
1993-07-30 |
1995-03-16 |
Joseph Dougherty |
Efficient gene transfer into primary lymphocytes
|
|
FR2708622B1
(fr)
|
1993-08-02 |
1997-04-18 |
Raymond Hamers |
Vecteur recombinant contenant une séquence d'un gène de lipoprotéine de structure pour l'expression de séquences de nucléotides.
|
|
US5550213A
(en)
|
1993-12-27 |
1996-08-27 |
Rutgers, The State University Of New Jersey |
Inhibitors of urokinase plasminogen activator
|
|
FR2714830B1
(fr)
|
1994-01-10 |
1996-03-22 |
Rhone Poulenc Rorer Sa |
Composition contenant des acides nucléiques, préparation et utilisations.
|
|
FR2715847B1
(fr)
|
1994-02-08 |
1996-04-12 |
Rhone Poulenc Rorer Sa |
Composition contenant des acides nucléiques, préparation et utilisations.
|
|
FR2716459B1
(fr)
|
1994-02-22 |
1996-05-10 |
Univ Paris Curie |
Système hôte-vecteur utilisable en thérapie génique.
|
|
WO1995026411A2
(en)
|
1994-03-25 |
1995-10-05 |
The Uab Research Foundation |
Composition and methods for creating syngeneic recombinant virus-producing cells
|
|
US5739118A
(en)
|
1994-04-01 |
1998-04-14 |
Apollon, Inc. |
Compositions and methods for delivery of genetic material
|
|
WO1995028494A1
(en)
|
1994-04-15 |
1995-10-26 |
Targeted Genetics Corporation |
Gene delivery fusion proteins
|
|
US5571515A
(en)
|
1994-04-18 |
1996-11-05 |
The Wistar Institute Of Anatomy & Biology |
Compositions and methods for use of IL-12 as an adjuvant
|
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US5565204A
(en)
|
1994-08-24 |
1996-10-15 |
American Cyanamid Company |
Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
|
|
US5837533A
(en)
|
1994-09-28 |
1998-11-17 |
American Home Products Corporation |
Complexes comprising a nucleic acid bound to a cationic polyamine having an endosome disruption agent
|
|
GB9422096D0
(en)
|
1994-11-02 |
1994-12-21 |
Biocine Spa |
Combined meningitis vaccine
|
|
FR2727679B1
(fr)
|
1994-12-05 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux agents de transfection et leurs applications pharmaceutiques
|
|
BE1008978A5
(fr)
|
1994-12-27 |
1996-10-01 |
Solvay |
Adjuvants pour vaccins.
|
|
IL116816A
(en)
|
1995-01-20 |
2003-05-29 |
Rhone Poulenc Rorer Sa |
Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof
|
|
FR2730637B1
(fr)
|
1995-02-17 |
1997-03-28 |
Rhone Poulenc Rorer Sa |
Composition pharmaceutique contenant des acides nucleiques, et ses utilisations
|
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
|
WO1996039036A1
(en)
|
1995-06-05 |
1996-12-12 |
The University Of Alabama At Birmingham Research Foundation |
Composition and methods for creating syngeneic recombinant virus-producing cells
|
|
ATE339436T1
(de)
|
1995-06-07 |
2006-10-15 |
Sanofi Pasteur Inc |
Expression von lipoproteinen
|
|
FR2741358B1
(fr)
|
1995-11-17 |
1998-01-02 |
Centre Nat Rech Scient |
Production de vecteurs retroviraux par l'intermediaire de vecteurs viraux a base de virus a adn
|
|
US6355255B1
(en)
|
1998-12-07 |
2002-03-12 |
Regents Of The University Of Minnesota |
Streptococcal C5a peptidase vaccine
|
|
US5846547A
(en)
|
1996-01-22 |
1998-12-08 |
Regents Of The University Of Minnesota |
Streptococcal C5a peptidase vaccine
|
|
US6048527A
(en)
|
1996-08-27 |
2000-04-11 |
Chiron Corporation |
Antibodies that define unique Meningococcal B epitopes and vaccine compositions
|
|
ES2166097T5
(es)
|
1996-08-27 |
2007-03-16 |
Novartis Vaccines And Diagnostics, Inc. |
Glicoconjugados de neisseria meningitidis de serogrupo b y procedimientos para usarlos.
|
|
AU5426098A
(en)
|
1996-10-24 |
1998-05-15 |
Emory University |
Invasion associated genes from (neisseria meningitidis) serogroup
|
|
GB9622159D0
(en)
|
1996-10-24 |
1996-12-18 |
Solvay Sociutu Anonyme |
Polyanionic polymers as adjuvants for mucosal immunization
|
|
GB9622660D0
(en)
|
1996-10-31 |
1997-01-08 |
Biocine Spa |
Immunogenic detoxified mutant toxin
|
|
US6113918A
(en)
|
1997-05-08 |
2000-09-05 |
Ribi Immunochem Research, Inc. |
Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
|
|
HUP0004589A3
(en)
|
1997-06-30 |
2003-08-28 |
Centre Nat Rech Scient |
Improved method for transferring nucleic acid into the striped muscle and combination therefor
|
|
IL133708A0
(en)
|
1997-06-30 |
2001-04-30 |
Rhone Poulence Rorer S A |
Improved method for transferring nucleic acid into multicelled eukaryotic organism cells and combination thereof
|
|
WO1999001175A1
(en)
|
1997-06-30 |
1999-01-14 |
Rhone-Poulenc Rorer S.A. |
Device for optimized electrotransfer of nucleic acid vectors to tissues in vivo
|
|
JPH1144977A
(ja)
|
1997-07-25 |
1999-02-16 |
Copyer Co Ltd |
画像形成装置
|
|
CA2301942C
(en)
|
1997-08-27 |
2011-05-31 |
Chiron Corporation |
Molecular mimetics of meningococcal b epitopes
|
|
CN1263854C
(zh)
|
1997-11-06 |
2006-07-12 |
启龙股份公司 |
奈瑟球菌抗原
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
AU1979599A
(en)
|
1998-01-14 |
1999-08-02 |
Chiron S.P.A. |
(neisseria meningitidis) antigens
|
|
DK1053329T3
(da)
|
1998-02-03 |
2010-01-25 |
Ct Disease Contr & Prevention |
Rekombinant lipideret PsaA-protein, fremgangsmåder til fremstilling og anvendelse
|
|
GB9806456D0
(en)
|
1998-03-25 |
1998-05-27 |
Smithkline Beecham Biolog |
Vaccine composition
|
|
GB9808734D0
(en)
|
1998-04-23 |
1998-06-24 |
Smithkline Beecham Biolog |
Novel compounds
|
|
GB9808932D0
(en)
|
1998-04-27 |
1998-06-24 |
Chiron Spa |
Polyepitope carrier protein
|
|
EP2261352A3
(en)
|
1998-05-01 |
2012-01-04 |
Novartis Vaccines and Diagnostics, Inc. |
Neisseria meningitidis antigens and compositions
|
|
BR9910749A
(pt)
|
1998-05-29 |
2001-02-13 |
Chiron Corp |
Composições e vacinas imunogênicas combinadas para meningites b e c e método de induzir uma resposta imune por administração da mesma
|
|
DE69919754T2
(de)
|
1998-09-30 |
2005-09-01 |
Walter Reed Army Institute Of Research |
Verwendung von aufgereinigtem invaplex als impfstoff für gram-negativebakterien
|
|
ATE378066T1
(de)
|
1998-09-30 |
2007-11-15 |
Wyeth Corp |
Mutiertes cholera holotoxin als hilfsmittel
|
|
CN1911959A
(zh)
*
|
1998-10-09 |
2007-02-14 |
希龙公司 |
奈瑟球菌基因组序列及其用途
|
|
BR9914374A
(pt)
|
1998-10-09 |
2002-09-17 |
Chiron Corp |
Sequências genÈmicas de neisseria e métodos para seu uso
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6281337B1
(en)
|
1998-11-12 |
2001-08-28 |
Schering Corporation |
Methods for conversion of protein isoforms
|
|
CA2359486A1
(en)
|
1999-01-15 |
2000-07-20 |
Smithkline Beecham Biologicals S.A. |
Neisseria meningitidis polypeptide basb052
|
|
CA2360658A1
(en)
|
1999-01-22 |
2000-07-27 |
Smithkline Beecham Biologicals S.A. |
Neisseria meningitidis antigenic polypeptides, corresponding polynucleotides and protective antibodies
|
|
GB9902084D0
(en)
|
1999-01-29 |
1999-03-24 |
Smithkline Beecham Biolog |
Novel compounds
|
|
DE60040727D1
(de)
|
1999-02-05 |
2008-12-18 |
Merck & Co Inc |
Menschliche papillomavirus impfstoff-formulierungen
|
|
JP4812942B2
(ja)
|
1999-02-26 |
2011-11-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
ＣＧモチーフを含むオリゴヌクレオチドを用いるＮｅｉｓｓｅｒｉａ抗原殺菌活性の増強
|
|
US6245568B1
(en)
|
1999-03-26 |
2001-06-12 |
Merck & Co., Inc. |
Human papilloma virus vaccine with disassembled and reassembled virus-like particles
|
|
US7115730B1
(en)
|
1999-04-27 |
2006-10-03 |
Chiron Srl |
Immunogenic detoxified mutant E. coli LT-A-toxin
|
|
JP2003518363A
(ja)
|
1999-04-30 |
2003-06-10 |
カイロン エセ．ピー．アー． |
保存されたナイセリア抗原
|
|
CN101033467A
(zh)
|
1999-04-30 |
2007-09-12 |
希龙公司 |
奈瑟球菌基因组序列及其用法
|
|
EP2270173B1
(en)
|
1999-05-19 |
2016-01-06 |
GlaxoSmithKline Biologicals SA |
Combination neisserial compositions
|
|
GB9911683D0
(en)
|
1999-05-19 |
1999-07-21 |
Chiron Spa |
Antigenic peptides
|
|
GB9916529D0
(en)
|
1999-07-14 |
1999-09-15 |
Chiron Spa |
Antigenic peptides
|
|
US7384640B1
(en)
|
1999-09-30 |
2008-06-10 |
Wyeth Holdings Corporation |
Mutant cholera holotoxin as an adjuvant
|
|
RU2281956C2
(ru)
|
1999-10-29 |
2006-08-20 |
Чирон С.Р.Л. |
Антигенные пептиды neisseria
|
|
GB9928196D0
(en)
|
1999-11-29 |
2000-01-26 |
Chiron Spa |
Combinations of B, C and other antigens
|
|
CA2390344C
(en)
|
1999-11-29 |
2014-08-26 |
Chiron Spa |
85kda neisserial antigen
|
|
PT1233784E
(pt)
|
1999-12-02 |
2008-11-03 |
Novartis Vaccines & Diagnostic |
Composições e métodos para a estabilização de moléculas biológicas após a liofilização
|
|
PT2289545T
(pt)
|
2000-01-17 |
2016-09-06 |
Glaxosmithkline Biologicals Sa |
Vacina de omv suplementada contra meningococos
|
|
ES2281409T3
(es)
|
2000-02-28 |
2007-10-01 |
Novartis Vaccines And Diagnostics S.R.L. |
Expresion heterologa de proteinas de neisseria.
|
|
AU2001281812B2
(en)
|
2000-06-08 |
2005-04-07 |
Valneva Austria Gmbh |
Immunostimulatory oligodeoxynucleotides
|
|
AT410635B
(de)
|
2000-10-18 |
2003-06-25 |
Cistem Biotechnologies Gmbh |
Vakzin-zusammensetzung
|
|
OA12590A
(en)
|
2001-01-23 |
2006-06-08 |
Aventis Pasteur |
Multivalent meningococcal polysaccharide-protein conjugate vaccine.
|
|
GB0103424D0
(en)
|
2001-02-12 |
2001-03-28 |
Chiron Spa |
Gonococcus proteins
|
|
CA2441327A1
(en)
|
2001-03-30 |
2002-10-10 |
Geneprot, Inc. |
Human arginine-rich protein-related compositions
|
|
WO2002083710A2
(en)
|
2001-04-13 |
2002-10-24 |
Wyeth Holdings Corporation |
Removal of bacterial endotoxin in a protein solution by immobilized metal affinity chromatography
|
|
CN1306956C
(zh)
|
2001-04-17 |
2007-03-28 |
希龙公司 |
诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物
|
|
KR100898648B1
(ko)
|
2001-06-07 |
2009-05-22 |
와이어쓰 홀딩스 코포레이션 |
보조제로서 콜레라 홀로톡신의 돌연변이체 형태
|
|
CA2449670A1
(en)
|
2001-06-07 |
2002-12-12 |
Wyeth Holdings Corporation |
Mutant forms of cholera holotoxin as an adjuvant
|
|
GB0115176D0
(en)
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
|
CA2452720C
(en)
|
2001-07-26 |
2012-04-17 |
Chiron S.R.L. |
Vaccines comprising aluminium adjuvants and histidine
|
|
GB0121591D0
(en)
|
2001-09-06 |
2001-10-24 |
Chiron Spa |
Hybrid and tandem expression of neisserial proteins
|
|
EP1436385A4
(en)
|
2001-09-14 |
2005-12-14 |
Invitrogen Corp |
DNA POLYMERASES AND MUTANTS CORRESPONDING
|
|
MX339524B
(es)
|
2001-10-11 |
2016-05-30 |
Wyeth Corp |
Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
|
|
GB0129007D0
(en)
|
2001-12-04 |
2002-01-23 |
Chiron Spa |
Adjuvanted antigenic meningococcal compositions
|
|
PT1777236T
(pt)
|
2002-03-26 |
2017-02-13 |
Glaxosmithkline Biologicals Sa |
Sacáridos modificados possuindo estabilidade melhorada em água para utilização como um medicamento
|
|
MXPA04011249A
(es)
|
2002-05-14 |
2005-06-06 |
Chiron Srl |
Vacunas mucosales con adyuvante de quitosano y antigenos meningococicos.
|
|
GB0302218D0
(en)
|
2003-01-30 |
2003-03-05 |
Chiron Sri |
Vaccine formulation & Mucosal delivery
|
|
NZ536859A
(en)
|
2002-05-14 |
2007-11-30 |
Chiron Srl |
Mucosal combination vaccines for bacterial meningitis
|
|
US7785608B2
(en)
|
2002-08-30 |
2010-08-31 |
Wyeth Holdings Corporation |
Immunogenic compositions for the prevention and treatment of meningococcal disease
|
|
GB0220194D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Improved vesicles
|
|
GB0220198D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Modified saccharides,conjugates thereof and their manufacture
|
|
HUE031886T2
(en)
|
2002-10-11 |
2017-08-28 |
Glaxosmithkline Biologicals Sa |
Polypeptide vaccines for extensive protection against hypervirulent meningococcal lines
|
|
EP1562982B1
(en)
|
2002-11-15 |
2010-05-05 |
Novartis Vaccines and Diagnostics S.r.l. |
Unexpected surface proteins in neisseria meningitidis
|
|
GB0227346D0
(en)
|
2002-11-22 |
2002-12-31 |
Chiron Spa |
741
|
|
CA2512917A1
(en)
|
2003-01-15 |
2004-08-05 |
Wyeth Holdings Corporation |
Methods for increasing neisseria protein expression
|
|
ES2461350T3
(es)
|
2003-01-30 |
2014-05-19 |
Novartis Ag |
Vacunas inyectables contra múltiples serogrupos de meningococos
|
|
US20060251675A1
(en)
|
2003-03-17 |
2006-11-09 |
Michael Hagen |
Mutant cholera holotoxin as an adjuvant and an antigen carrier protein
|
|
MXPA05011110A
(es)
|
2003-04-16 |
2006-01-24 |
Wyeth Corp |
Composiciones inmunogenicas novedosas para la prevencion y tratamiento de un padecimiento originado por meningococos.
|
|
EP1631264B8
(en)
|
2003-06-02 |
2017-05-24 |
GlaxoSmithKline Biologicals SA |
Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
|
|
EP2364725A3
(en)
|
2003-06-23 |
2012-05-09 |
Sanofi Pasteur Inc. |
Immunization method against neisseria meningitidis serogroups a and c
|
|
GB0316560D0
(en)
|
2003-07-15 |
2003-08-20 |
Chiron Srl |
Vesicle filtration
|
|
GB0323103D0
(en)
|
2003-10-02 |
2003-11-05 |
Chiron Srl |
De-acetylated saccharides
|
|
CN103357002A
(zh)
|
2003-10-02 |
2013-10-23 |
诺华疫苗和诊断有限公司 |
多种脑膜炎球菌血清群的液体疫苗
|
|
MXPA06007635A
(es)
|
2003-12-30 |
2007-01-30 |
Wyeth Corp |
Formulaciones de proteinas hidrofobas en una composicion inmunogenica que tiene tolerabilidad mejorada.
|
|
GB0406013D0
(en)
|
2004-03-17 |
2004-04-21 |
Chiron Srl |
Analysis of saccharide vaccines without interference
|
|
GB0408978D0
(en)
|
2004-04-22 |
2004-05-26 |
Chiron Srl |
Meningococcal fermentation for preparing conjugate vaccines
|
|
GB0408977D0
(en)
|
2004-04-22 |
2004-05-26 |
Chiron Srl |
Immunising against meningococcal serogroup Y using proteins
|
|
GB0409745D0
(en)
|
2004-04-30 |
2004-06-09 |
Chiron Srl |
Compositions including unconjugated carrier proteins
|
|
ATE512670T1
(de)
|
2004-04-30 |
2011-07-15 |
Novartis Vaccines & Diagnostic |
Meningokokken-konjugat-impfung
|
|
GB0500787D0
(en)
|
2005-01-14 |
2005-02-23 |
Chiron Srl |
Integration of meningococcal conjugate vaccination
|
|
GB0410220D0
(en)
|
2004-05-07 |
2004-06-09 |
Kirkham Lea Ann |
Mutant pneumolysin proteins
|
|
GB0411387D0
(en)
|
2004-05-21 |
2004-06-23 |
Chiron Srl |
Analysis of saccharide length
|
|
GB0413868D0
(en)
|
2004-06-21 |
2004-07-21 |
Chiron Srl |
Dimensional anlaysis of saccharide conjugates
|
|
DE602005025647D1
(de)
|
2004-07-23 |
2011-02-10 |
Novartis Vaccines & Diagnostic |
Polypeptide für die oligomerisierung von antigenen
|
|
GB0419408D0
(en)
|
2004-09-01 |
2004-10-06 |
Chiron Srl |
741 chimeric polypeptides
|
|
GB0419846D0
(en)
|
2004-09-07 |
2004-10-13 |
Chiron Srl |
Vaccine adjuvants for saccharides
|
|
GB0424092D0
(en)
|
2004-10-29 |
2004-12-01 |
Chiron Srl |
Immunogenic bacterial vesicles with outer membrane proteins
|
|
GB0428394D0
(en)
|
2004-12-24 |
2005-02-02 |
Chiron Srl |
Saccharide conjugate vaccines
|
|
ES2616294T3
(es)
|
2005-01-27 |
2017-06-12 |
Children's Hospital & Research Center At Oakland |
Vacunas de vesículas basadas en GNA1870 para protección de amplio espectro contra enfermedades provocadas por Neisseria meningitidis
|
|
WO2006096701A2
(en)
|
2005-03-07 |
2006-09-14 |
Id Biomedical Corporation Of Quebec C.O.B. As Glaxosmithkline Biologicals North America |
Pharmaceutical liposomal compositions
|
|
ES2533248T3
(es)
|
2005-05-06 |
2015-04-08 |
Novartis Ag |
Inmunógenos para vacunas contra Meningitidis A
|
|
US8398983B2
(en)
|
2005-06-27 |
2013-03-19 |
Glaxosmithkline Biologicals, S.A. |
Immunogenic composition
|
|
NZ598367A
(en)
|
2005-09-01 |
2013-10-25 |
Novartis Vaccines & Diagnostic |
Multiple vaccination including serogroup C meningococcus
|
|
DE602005024320D1
(de)
|
2005-09-05 |
2010-12-02 |
Glaxosmithkline Biolog Sa |
Bakterizidie-serumtest für n. meningitidis spezifische antiseren
|
|
GB0524066D0
(en)
|
2005-11-25 |
2006-01-04 |
Chiron Srl |
741 ii
|
|
JP2009520771A
(ja)
|
2005-12-23 |
2009-05-28 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
コンジュゲートワクチン
|
|
PL2004225T3
(pl)
|
2006-03-22 |
2012-09-28 |
Novartis Ag |
Schematy immunizacji koniugatami meningokokowymi
|
|
TW200806315A
(en)
|
2006-04-26 |
2008-02-01 |
Wyeth Corp |
Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
|
|
WO2007127668A2
(en)
|
2006-04-26 |
2007-11-08 |
Wyeth |
Novel processes for coating container means which inhibit precipitation of polysaccharide-protein conjugate formulations
|
|
DE602007003596D1
(de)
|
2006-06-12 |
2010-01-14 |
Glaxosmithkline Biolog Sa |
Impfstoff
|
|
GB0612854D0
(en)
|
2006-06-28 |
2006-08-09 |
Novartis Ag |
Saccharide analysis
|
|
CA2656474A1
(en)
|
2006-06-29 |
2008-01-03 |
Novartis Ag |
Polypeptides from neisseria meningitidis
|
|
CA2657135C
(en)
|
2006-07-27 |
2016-03-15 |
Wyeth |
High-cell density fed-batch fermentation process for producing recombinant protein
|
|
AR064642A1
(es)
|
2006-12-22 |
2009-04-15 |
Wyeth Corp |
Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
|
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
|
CA2688268A1
(en)
|
2007-06-04 |
2008-12-11 |
Novartis Ag |
Formulation of meningitis vaccines
|
|
GB0713880D0
(en)
|
2007-07-17 |
2007-08-29 |
Novartis Ag |
Conjugate purification
|
|
GB0714963D0
(en)
|
2007-08-01 |
2007-09-12 |
Novartis Ag |
Compositions comprising antigens
|
|
EP2185576A4
(en)
|
2007-08-02 |
2011-01-12 |
Childrens Hosp & Res Ct Oak |
FHBP- AND LPXL1-BASED VESICIUM VACCINES FOR BROADBAND PROTECTION AGAINST NEISSERIA MENINGITIDIS-RELATED DISEASES
|
|
WO2009050586A1
(en)
|
2007-10-19 |
2009-04-23 |
Novartis Ag |
Meningococcal vaccine formulations
|
|
CN102356089B
(zh)
*
|
2008-02-21 |
2014-02-19 |
诺华股份有限公司 |
脑膜炎球菌fHBP多肽
|
|
ES2615390T3
(es)
|
2008-03-05 |
2017-06-06 |
Sanofi Pasteur |
Proceso para estabilizar una composición de vacuna que contiene adyuvante
|
|
ES2557282T3
(es)
|
2008-03-10 |
2016-01-25 |
Children's Hospital & Research Center At Oakland |
Proteínas quiméricas de unión al factor H (fHBP) que contienen un dominio B heterólogo, y métodos de uso
|
|
WO2009143168A2
(en)
|
2008-05-19 |
2009-11-26 |
Novartis Ag |
Vaccine assays
|
|
JP5723768B2
(ja)
|
2008-05-30 |
2015-05-27 |
ザ ユナイテッド ステイツ オブ アメリカ， アズ レプレゼンテッド バイ ザ セクレタリー オブ ジ アーミー， オン ビハーフ オブ ウォルター リード アーミー インスティチュート オブ リサーチ |
髄膜炎菌性多価未変性外膜小胞ワクチン、その作製方法およびその使用
|
|
WO2010027872A1
(en)
|
2008-08-27 |
2010-03-11 |
Children's Hospital & Research Center At Oakland |
Complement factor h-based assays for serum bactericidal activity against neisseria meningitidis
|
|
WO2010028096A2
(en)
|
2008-09-03 |
2010-03-11 |
Children's Hospital & Research Center At Oakland |
Peptides presenting an epitope of an a domain of factor h binding protein and methods of use
|
|
IT1394288B1
(it)
|
2008-09-12 |
2012-06-06 |
Novartis Vaccines & Diagnostic |
Immunogeni di proteine che legano il fattore h.
|
|
EP2362767B1
(en)
|
2008-10-29 |
2017-12-06 |
Ablynx N.V. |
Formulations of single domain antigen binding molecules
|
|
GB0822634D0
(en)
|
2008-12-11 |
2009-01-21 |
Novartis Ag |
Meningitis vaccines
|
|
JP2012512240A
(ja)
|
2008-12-17 |
2012-05-31 |
ノバルティス アーゲー |
ヘモグロビン受容体を含む髄膜炎菌ワクチン
|
|
HUE049695T2
(hu)
|
2009-03-24 |
2020-10-28 |
Glaxosmithkline Biologicals Sa |
Adjuváló H meningococcus faktort kötõ fehérje
|
|
EP3017826A1
(en)
|
2009-03-24 |
2016-05-11 |
Novartis AG |
Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
|
|
CA2759400A1
(en)
*
|
2009-04-30 |
2010-11-04 |
Children's Hospital & Research Center At Oakland |
Chimeric factor h binding proteins (fhbp) and methods of use
|
|
US9365885B2
(en)
|
2009-06-16 |
2016-06-14 |
Puiying Annie Mak |
High-throughput complement-mediated antibody-dependent and opsonic bactericidal assays
|
|
US20110076300A1
(en)
*
|
2009-08-27 |
2011-03-31 |
Mariagrazia Pizza |
Hybrid Polypeptides Including Meningococcal fHBP Sequences
|
|
CN102724988B
(zh)
|
2009-09-30 |
2014-09-10 |
诺华股份有限公司 |
脑膜炎球菌fHBP多肽的表达
|
|
GB0917647D0
(en)
|
2009-10-08 |
2009-11-25 |
Glaxosmithkline Biolog Sa |
Expression system
|
|
CA2779816A1
(en)
|
2009-10-27 |
2011-05-05 |
Novartis Ag |
Modified meningococcal fhbp polypeptides
|
|
JP5781542B2
(ja)
|
2009-12-30 |
2015-09-24 |
ノバルティス アーゲー |
Ｅ．ｃｏｌｉキャリアタンパク質に結合体化した多糖免疫原
|
|
GB201003922D0
(en)
|
2010-03-09 |
2010-04-21 |
Glaxosmithkline Biolog Sa |
Conjugation process
|
|
EP2544714A1
(en)
|
2010-03-10 |
2013-01-16 |
GlaxoSmithKline Biologicals S.A. |
Vaccine composition
|
|
CN102802662A
(zh)
|
2010-03-18 |
2012-11-28 |
诺华有限公司 |
用于脑膜炎球菌血清组b的含佐剂疫苗
|
|
ES2910199T3
(es)
|
2010-03-30 |
2022-05-11 |
Childrens Hospital & Res Center At Oakland |
Proteínas de unión al factor H (fHbp) con propiedades alteradas y métodos de uso de las mismas
|
|
CA2803239A1
(en)
|
2010-06-25 |
2011-12-29 |
Novartis Ag |
Combinations of meningococcal factor h binding proteins
|
|
KR101594228B1
(ko)
|
2010-08-23 |
2016-02-15 |
와이어쓰 엘엘씨 |
네이세리아 메닌기티디스 ｒＬＰ２０８６ 항원의 안정한 제제
|
|
ES2744471T3
(es)
|
2010-09-04 |
2020-02-25 |
Glaxosmithkline Biologicals Sa |
Ensayos de anticuerpos bactericidas para evaluar la inmunogenia y la potencia de vacunas de sacárido capsular meningocócico
|
|
US20120070457A1
(en)
|
2010-09-10 |
2012-03-22 |
J. Craig Venter Institute, Inc. |
Polypeptides from neisseria meningitidis
|
|
NZ607224A
(en)
*
|
2010-09-10 |
2014-11-28 |
Wyeth Llc |
Non-lipidated variants of neisseria meningitidis orf2086 antigens
|
|
GB201015132D0
(en)
|
2010-09-10 |
2010-10-27 |
Univ Bristol |
Vaccine composition
|
|
BR112013005626B1
(pt)
|
2010-09-10 |
2022-07-26 |
Glaxosmithkline Biologicals Sa |
Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
|
|
GB201101665D0
(en)
|
2011-01-31 |
2011-03-16 |
Novartis Ag |
Immunogenic compositions
|
|
MX359256B
(es)
*
|
2012-03-09 |
2018-09-19 |
Pfizer |
Composiciones de neisseria meningitidis y metodos de las mismas.
|
|
US9802987B2
(en)
|
2013-03-08 |
2017-10-31 |
Pfizer Inc. |
Immunogenic fusion polypeptides
|
|
WO2014190204A1
(en)
*
|
2013-05-22 |
2014-11-27 |
Pearl Therapeutics, Inc. |
Compositions, methods & systems for respiratory delivery of three or more active agents
|
|
RU2662968C2
(ru)
|
2013-09-08 |
2018-07-31 |
Пфайзер Инк. |
Иммуногенная композиция против neisseria meningitidis (варианты)
|