DE60039450D1 - Zusammensetzungen und methoden zur stabilisierung von biologischen molekülen nach lyophilisierung - Google Patents

Zusammensetzungen und methoden zur stabilisierung von biologischen molekülen nach lyophilisierung

Info

Publication number
DE60039450D1
DE60039450D1 DE60039450T DE60039450T DE60039450D1 DE 60039450 D1 DE60039450 D1 DE 60039450D1 DE 60039450 T DE60039450 T DE 60039450T DE 60039450 T DE60039450 T DE 60039450T DE 60039450 D1 DE60039450 D1 DE 60039450D1
Authority
DE
Germany
Prior art keywords
biological molecules
compositions
methods
lyophilization
stabilizing biological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60039450T
Other languages
English (en)
Inventor
Irina Esikova
Sidney Wolfe
James Thomson
Hora Maninder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Novartis Vaccines and Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22611688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60039450(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc
Application granted granted Critical
Publication of DE60039450D1 publication Critical patent/DE60039450D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
DE60039450T 1999-12-02 2000-12-01 Zusammensetzungen und methoden zur stabilisierung von biologischen molekülen nach lyophilisierung Expired - Lifetime DE60039450D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16848699P 1999-12-02 1999-12-02
PCT/US2000/042484 WO2001041800A2 (en) 1999-12-02 2000-12-01 Compositions and methods for stabilizing biological molecules upon lyophilization

Publications (1)

Publication Number Publication Date
DE60039450D1 true DE60039450D1 (de) 2008-08-21

Family

ID=22611688

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60039450T Expired - Lifetime DE60039450D1 (de) 1999-12-02 2000-12-01 Zusammensetzungen und methoden zur stabilisierung von biologischen molekülen nach lyophilisierung

Country Status (10)

Country Link
EP (2) EP1233784B1 (de)
JP (2) JP4948731B2 (de)
AT (1) ATE400296T1 (de)
CA (1) CA2393298C (de)
CY (1) CY1108382T1 (de)
DE (1) DE60039450D1 (de)
DK (1) DK1233784T3 (de)
ES (1) ES2307553T3 (de)
PT (1) PT1233784E (de)
WO (1) WO2001041800A2 (de)

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* Cited by examiner, † Cited by third party
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ES2307553T3 (es) 1999-12-02 2008-12-01 Novartis Vaccines And Diagnostics, Inc. Composiciones y procedimientos para estabilizar moleculas biologicas tras liofilizacion.
PT2332581E (pt) 2001-01-23 2015-10-16 Sanofi Pasteur Inc Vacina meningocócica tri- ou tetravalente de conjugados de polissacárido e crm-197
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
WO2003009869A1 (en) * 2001-07-26 2003-02-06 Chiron Srl. Vaccines comprising aluminium adjuvants and histidine
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
BR0315767A (pt) 2002-11-01 2005-09-06 Glaxosmithkline Biolog Sa Composição imunogência, método para fabricar uma vacina, kit, vacina, recipiente com uma superfìcie interna repelente à água, e, método para preservar uma composição que compreende ipv e um agente estabilizador
JP4827726B2 (ja) 2003-01-30 2011-11-30 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル 複数の髄膜炎菌血清群に対する注射可能ワクチン
EP1651275A1 (de) * 2003-08-05 2006-05-03 Fuji Photo Film B.V. Verwendung von rekombinanten oder synthetischen gelatineartigen proteinen als stabilisator in lyophilisierten pharmazeutischen zusammensetzungen
US7883709B2 (en) 2003-10-23 2011-02-08 Novartis Ag Stabilised compositions
GB0404586D0 (en) * 2004-03-01 2004-04-07 Britannia Pharmaceuticals Ltd Improvements in or relating to organic materials
GB0409745D0 (en) 2004-04-30 2004-06-09 Chiron Srl Compositions including unconjugated carrier proteins
US8431136B2 (en) 2005-06-27 2013-04-30 Glaxosmithkline Biologicals S.A. Immunogenic composition
ES2670231T3 (es) 2006-03-22 2018-05-29 Glaxosmithkline Biologicals S.A. Regímenes para inmunización con conjugados meningocócicos
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
TW200806315A (en) * 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
TW201009337A (en) * 2008-05-30 2010-03-01 Intervet Int Bv Analytical method to monitor vaccine potency and stability
CA2739352C (en) 2008-10-29 2021-07-13 Wyeth Llc Methods for purification of single domain antigen binding molecules
KR101581986B1 (ko) * 2008-10-29 2016-01-04 아블린쓰 엔.브이. 단일 도메인 항원 결합 분자의 제형
CN102933229A (zh) 2010-06-04 2013-02-13 惠氏有限责任公司 疫苗制剂
WO2012025873A2 (en) 2010-08-23 2012-03-01 Wyeth Llc STABLE FORMULATIONS OF NEISSERIA MENINGITIDIS rLP2086 ANTIGENS
PE20140173A1 (es) 2010-09-10 2014-02-20 Wyeth Llc Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis
RU2013144207A (ru) 2011-03-02 2015-04-10 Новартис Аг Комбинированные вакцины с пониженными дозами антигена и/или адъюванта
US9512185B2 (en) * 2011-06-01 2016-12-06 Xiamen University Fusion protein comprising diphtheria toxin non-toxic mutant CRM197 or fragment thereof
EP2793939A1 (de) * 2011-12-23 2014-10-29 Novartis AG Stabile zusammensetzungen zur immunisierung gegen staphylococcus aureus
US9283270B2 (en) 2012-01-20 2016-03-15 Serum Institute Of India Ltd. Method for stabilization of biological molecules
EP2822584A1 (de) 2012-03-08 2015-01-14 Novartis AG Kombinationsimpfstoffe mit tlr4-agonisten
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
SG10201602558UA (en) 2012-03-09 2016-05-30 Pfizer Neisseria meningitidis compositions and methods thereof
KR102282726B1 (ko) * 2012-05-30 2021-07-29 더 브리검 앤드 우먼즈 하스피털, 인크. 폴리사카라이드 조성물 및 사용 방법
EP2866792A4 (de) * 2012-06-28 2016-08-17 Ansun Biopharma Inc Mikropartikelformulierungen zur abgabe an die unteren und zentralen atemwege und verfahren zur herstellung
CN104487086B (zh) * 2012-07-07 2019-08-30 巴拉特生物技术国际有限公司 无动物源的不含酒精的疫苗组合物及其制备方法
CA2882619A1 (en) 2012-09-06 2014-03-13 Novartis Ag Combination vaccines with serogroup b meningococcus and d/t/p
CN104717977A (zh) 2012-10-03 2015-06-17 诺华股份有限公司 免疫原性组合物
CN105007935A (zh) 2012-12-18 2015-10-28 葛兰素史密丝克莱恩生物有限公司 用于保护免于白喉和/或破伤风的缀合物
EP2964665B1 (de) 2013-03-08 2018-08-01 Pfizer Inc Immunogene fusionspolypeptide
CA2923129C (en) 2013-09-08 2020-06-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
BR112017017460A2 (pt) 2015-02-19 2018-04-10 Pfizer Inc. composições de neisseria meningitidis e métodos das mesmas
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
EP3876982A1 (de) 2018-11-06 2021-09-15 GlaxoSmithKline Biologicals S.A. Immunogene zusammensetzungen
GB202208089D0 (en) * 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9422096D0 (en) * 1994-11-02 1994-12-21 Biocine Spa Combined meningitis vaccine
JPH11510170A (ja) * 1995-07-27 1999-09-07 ジェネンテック インコーポレーテッド タンパク質の処方
ES2307553T3 (es) 1999-12-02 2008-12-01 Novartis Vaccines And Diagnostics, Inc. Composiciones y procedimientos para estabilizar moleculas biologicas tras liofilizacion.

Also Published As

Publication number Publication date
CY1108382T1 (el) 2014-02-12
EP2292263A2 (de) 2011-03-09
WO2001041800A9 (en) 2002-08-01
CA2393298C (en) 2011-02-01
DK1233784T3 (da) 2008-09-01
CA2393298A1 (en) 2001-06-14
JP2003516361A (ja) 2003-05-13
WO2001041800A3 (en) 2002-01-03
JP2011137047A (ja) 2011-07-14
ES2307553T3 (es) 2008-12-01
ATE400296T1 (de) 2008-07-15
JP4948731B2 (ja) 2012-06-06
EP1233784B1 (de) 2008-07-09
WO2001041800A2 (en) 2001-06-14
PT1233784E (pt) 2008-11-03
EP1233784A2 (de) 2002-08-28
EP2292263A3 (de) 2011-07-27

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