CY1108382T1 - Συνθεσεις και μεθοδοι για σταθεροποιηση βιολογικων μοριων κατα την λυοφιληση - Google Patents
Συνθεσεις και μεθοδοι για σταθεροποιηση βιολογικων μοριων κατα την λυοφιλησηInfo
- Publication number
- CY1108382T1 CY1108382T1 CY20081101074T CY081101074T CY1108382T1 CY 1108382 T1 CY1108382 T1 CY 1108382T1 CY 20081101074 T CY20081101074 T CY 20081101074T CY 081101074 T CY081101074 T CY 081101074T CY 1108382 T1 CY1108382 T1 CY 1108382T1
- Authority
- CY
- Cyprus
- Prior art keywords
- biological molecules
- compositions
- methods
- molecules during
- during lyophilization
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16848699P | 1999-12-02 | 1999-12-02 | |
EP00992589A EP1233784B1 (de) | 1999-12-02 | 2000-12-01 | Zusammensetzungen und methoden zur stabilisierung von biologischen molekülen nach lyophilisierung |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108382T1 true CY1108382T1 (el) | 2014-02-12 |
Family
ID=22611688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081101074T CY1108382T1 (el) | 1999-12-02 | 2008-09-30 | Συνθεσεις και μεθοδοι για σταθεροποιηση βιολογικων μοριων κατα την λυοφιληση |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP1233784B1 (de) |
JP (2) | JP4948731B2 (de) |
AT (1) | ATE400296T1 (de) |
CA (1) | CA2393298C (de) |
CY (1) | CY1108382T1 (de) |
DE (1) | DE60039450D1 (de) |
DK (1) | DK1233784T3 (de) |
ES (1) | ES2307553T3 (de) |
PT (1) | PT1233784E (de) |
WO (1) | WO2001041800A2 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2393298C (en) | 1999-12-02 | 2011-02-01 | Chiron Corporation | Compositions and methods for stabilizing biological molecules upon lyophilization |
JP2005504718A (ja) | 2001-01-23 | 2005-02-17 | アヴェンティス パストゥール | 多価髄膜炎菌多糖−タンパク質複合ワクチン |
GB0115176D0 (en) * | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
WO2003009869A1 (en) * | 2001-07-26 | 2003-02-06 | Chiron Srl. | Vaccines comprising aluminium adjuvants and histidine |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
US8409587B2 (en) | 2002-11-01 | 2013-04-02 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
CN102302776B (zh) | 2003-01-30 | 2014-06-18 | 诺华疫苗和诊断有限公司 | 抗多种脑膜炎球菌血清组的可注射性疫苗 |
US20070031501A1 (en) * | 2003-08-05 | 2007-02-08 | Andries Van Es | Use of recombinant or synthetic gelatin-like proteins as stabiliser in lyophilized pharmaceutical compositions |
ES2379267T3 (es) | 2003-10-23 | 2012-04-24 | Novartis Vaccines And Diagnostics, Inc. | Composiciones estabilizadas |
GB0404586D0 (en) * | 2004-03-01 | 2004-04-07 | Britannia Pharmaceuticals Ltd | Improvements in or relating to organic materials |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
US8329184B2 (en) | 2005-06-27 | 2012-12-11 | Glaxosmithkline Biologicals S.A. | Process for manufacturing vaccines |
WO2007111940A2 (en) | 2006-03-22 | 2007-10-04 | Novartis Ag | Regimens for immunisation with meningococcal conjugates |
US10828361B2 (en) | 2006-03-22 | 2020-11-10 | Glaxosmithkline Biologicals Sa | Regimens for immunisation with meningococcal conjugates |
TW200806315A (en) * | 2006-04-26 | 2008-02-01 | Wyeth Corp | Novel formulations which stabilize and inhibit precipitation of immunogenic compositions |
TW201009337A (en) * | 2008-05-30 | 2010-03-01 | Intervet Int Bv | Analytical method to monitor vaccine potency and stability |
MX345226B (es) * | 2008-10-29 | 2017-01-20 | Ablynx Nv | Formulaciones de moleculas de union a antigeno de dominio sencillo. |
KR20110079693A (ko) | 2008-10-29 | 2011-07-07 | 와이어쓰 엘엘씨 | 단일 도메인 항원 결합 분자의 정제 방법 |
AU2011262346B2 (en) | 2010-06-04 | 2014-12-11 | Wyeth Llc | Streptococcus pneumoniae vaccine formulations |
KR101594228B1 (ko) | 2010-08-23 | 2016-02-15 | 와이어쓰 엘엘씨 | 네이세리아 메닌기티디스 rLP2086 항원의 안정한 제제 |
AU2011300409B2 (en) | 2010-09-10 | 2015-03-26 | Wyeth Llc | Non-lipidated variants of Neisseria meningitidis ORF2086 antigens |
RU2013144207A (ru) | 2011-03-02 | 2015-04-10 | Новартис Аг | Комбинированные вакцины с пониженными дозами антигена и/или адъюванта |
KR101839496B1 (ko) | 2011-06-01 | 2018-03-19 | 시아먼 유니버시티 | 디프테리아 독소 무독성 돌연변이 씨알엠197 또는 그의 단편을 포함하는 융합 단백질 |
JP2015500864A (ja) * | 2011-12-23 | 2015-01-08 | ノバルティス アーゲー | 黄色ブドウ球菌(Staphylococcusaureus)に対して免疫するための安定な組成物 |
US9283270B2 (en) | 2012-01-20 | 2016-03-15 | Serum Institute Of India Ltd. | Method for stabilization of biological molecules |
JP2015509963A (ja) | 2012-03-08 | 2015-04-02 | ノバルティス アーゲー | Tlr4アゴニストを含む混合ワクチン |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
KR101763625B1 (ko) | 2012-03-09 | 2017-08-01 | 화이자 인코포레이티드 | 수막염균 조성물 및 이의 사용 방법 |
SG10201911609XA (en) * | 2012-05-30 | 2020-01-30 | Brigham & Womens Hospital Inc | Polysaccharide compositions and methods of use |
US20140099380A1 (en) * | 2012-06-28 | 2014-04-10 | Ansun Biopharma, Inc. | Microparticle Formulations for Delivery to the Lower and Central Respiratory Tract and Methods of Manufacture |
WO2014009971A2 (en) * | 2012-07-07 | 2014-01-16 | Bharat Biotech International Limited | Non-alcoholic vaccine compositions free from animal- origin and process for preparation thereof |
JP6324961B2 (ja) | 2012-09-06 | 2018-05-16 | ノバルティス アーゲー | 血清群b髄膜炎菌とd/t/pとの組み合わせワクチン |
CN104582718B (zh) | 2012-10-03 | 2017-10-24 | 诺华股份有限公司 | 免疫原性组合物 |
WO2014095771A1 (en) | 2012-12-18 | 2014-06-26 | Novartis Ag | Conjugates for protecting against diphtheria and/or tetanus |
US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
US9822150B2 (en) | 2013-09-08 | 2017-11-21 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
KR20170103009A (ko) | 2015-02-19 | 2017-09-12 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
PE20191107A1 (es) | 2017-01-31 | 2019-08-26 | Pfizer | Composiciones de neisseria meningitidis y metodos respectivos |
AU2019376832B2 (en) | 2018-11-06 | 2024-01-25 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
GB202208089D0 (en) * | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9422096D0 (en) * | 1994-11-02 | 1994-12-21 | Biocine Spa | Combined meningitis vaccine |
JPH11510170A (ja) * | 1995-07-27 | 1999-09-07 | ジェネンテック インコーポレーテッド | タンパク質の処方 |
CA2393298C (en) | 1999-12-02 | 2011-02-01 | Chiron Corporation | Compositions and methods for stabilizing biological molecules upon lyophilization |
-
2000
- 2000-12-01 CA CA2393298A patent/CA2393298C/en not_active Expired - Lifetime
- 2000-12-01 JP JP2001543144A patent/JP4948731B2/ja not_active Expired - Lifetime
- 2000-12-01 PT PT00992589T patent/PT1233784E/pt unknown
- 2000-12-01 EP EP00992589A patent/EP1233784B1/de not_active Revoked
- 2000-12-01 ES ES00992589T patent/ES2307553T3/es not_active Expired - Lifetime
- 2000-12-01 DE DE60039450T patent/DE60039450D1/de not_active Expired - Lifetime
- 2000-12-01 AT AT00992589T patent/ATE400296T1/de active
- 2000-12-01 EP EP10180286A patent/EP2292263A3/de not_active Withdrawn
- 2000-12-01 DK DK00992589T patent/DK1233784T3/da active
- 2000-12-01 WO PCT/US2000/042484 patent/WO2001041800A2/en active Application Filing
-
2008
- 2008-09-30 CY CY20081101074T patent/CY1108382T1/el unknown
-
2011
- 2011-04-12 JP JP2011088528A patent/JP2011137047A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP2292263A2 (de) | 2011-03-09 |
PT1233784E (pt) | 2008-11-03 |
JP4948731B2 (ja) | 2012-06-06 |
ES2307553T3 (es) | 2008-12-01 |
WO2001041800A9 (en) | 2002-08-01 |
EP2292263A3 (de) | 2011-07-27 |
WO2001041800A2 (en) | 2001-06-14 |
JP2003516361A (ja) | 2003-05-13 |
DK1233784T3 (da) | 2008-09-01 |
EP1233784A2 (de) | 2002-08-28 |
EP1233784B1 (de) | 2008-07-09 |
WO2001041800A3 (en) | 2002-01-03 |
CA2393298A1 (en) | 2001-06-14 |
DE60039450D1 (de) | 2008-08-21 |
CA2393298C (en) | 2011-02-01 |
ATE400296T1 (de) | 2008-07-15 |
JP2011137047A (ja) | 2011-07-14 |
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