ATE405647T1 - Rekombinantes gelatin in impstoffen - Google Patents

Rekombinantes gelatin in impstoffen

Info

Publication number
ATE405647T1
ATE405647T1 AT00978469T AT00978469T ATE405647T1 AT E405647 T1 ATE405647 T1 AT E405647T1 AT 00978469 T AT00978469 T AT 00978469T AT 00978469 T AT00978469 T AT 00978469T AT E405647 T1 ATE405647 T1 AT E405647T1
Authority
AT
Austria
Prior art keywords
vaccines
recombinant gelatin
recombinant
gelatin
compositions
Prior art date
Application number
AT00978469T
Other languages
English (en)
Inventor
Robert Chang
Kari Kivirikko
Thomas Neff
David Olsen
James Polarek
Original Assignee
Fibrogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fibrogen Inc filed Critical Fibrogen Inc
Application granted granted Critical
Publication of ATE405647T1 publication Critical patent/ATE405647T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A23L29/281—Proteins, e.g. gelatin or collagen
    • A23L29/284—Gelatin; Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03C—PHOTOSENSITIVE MATERIALS FOR PHOTOGRAPHIC PURPOSES; PHOTOGRAPHIC PROCESSES, e.g. CINE, X-RAY, COLOUR, STEREO-PHOTOGRAPHIC PROCESSES; AUXILIARY PROCESSES IN PHOTOGRAPHY
    • G03C1/00—Photosensitive materials
    • G03C1/005—Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein
    • G03C1/04—Silver halide emulsions; Preparation thereof; Physical treatment thereof; Incorporation of additives therein with macromolecular additives; with layer-forming substances
    • G03C1/047—Proteins, e.g. gelatine derivatives; Hydrolysis or extraction products of proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
AT00978469T 1999-11-12 2000-11-10 Rekombinantes gelatin in impstoffen ATE405647T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16511499P 1999-11-12 1999-11-12
US20443700P 2000-05-15 2000-05-15

Publications (1)

Publication Number Publication Date
ATE405647T1 true ATE405647T1 (de) 2008-09-15

Family

ID=26861120

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978469T ATE405647T1 (de) 1999-11-12 2000-11-10 Rekombinantes gelatin in impstoffen

Country Status (16)

Country Link
US (3) US20030064074A1 (de)
EP (4) EP2011874A1 (de)
JP (2) JP4597454B2 (de)
KR (1) KR20020059719A (de)
CN (1) CN1309737C (de)
AT (1) ATE405647T1 (de)
AU (2) AU1591701A (de)
BR (1) BR0015508A (de)
CA (2) CA2390995A1 (de)
DE (1) DE60040012D1 (de)
ES (1) ES2315244T3 (de)
HK (2) HK1046004B (de)
IL (2) IL149459A0 (de)
MX (1) MXPA02004666A (de)
RU (1) RU2002112751A (de)
WO (2) WO2001034801A2 (de)

Families Citing this family (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE405647T1 (de) * 1999-11-12 2008-09-15 Fibrogen Inc Rekombinantes gelatin in impstoffen
US6992172B1 (en) * 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
EP1238675A1 (de) * 2001-03-06 2002-09-11 Fuji Photo Film B.V. Rekombinante gelatineartige Proteine zur Verwendung als Plasmaexpander
AU2003241288A1 (en) * 2002-04-11 2003-10-27 Fibrogen, Inc. Production of stable collagens
JP4226846B2 (ja) * 2002-06-07 2009-02-18 キャタレント・ジャパン株式会社 口腔内で崩壊可能なソフトカプセル剤
EP1398324A1 (de) * 2002-09-11 2004-03-17 Fuji Photo Film B.V. Gelatin-artige Proteine als Plasma-Expander und als Plasmaersatz geeignete Verbindungen
EP3241915B1 (de) 2002-10-16 2021-06-23 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis des west-nil-viruses
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
AU2003301654A1 (en) * 2002-10-22 2004-05-13 Dainippon Pharmaceutical Co., Ltd. Stabilized composition
US20040254347A1 (en) * 2002-11-25 2004-12-16 Academia Sinica Method of cross-linking peptides
WO2004056976A2 (en) 2002-12-23 2004-07-08 Fuji Photo Film B.V. Process for coating cell-culture support
US20060110406A1 (en) 2003-02-25 2006-05-25 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
CA2807534A1 (en) * 2003-02-25 2005-02-17 Medimmune Vaccines, Inc. Methods of producing influenza vaccine compositions
DE602004024834D1 (de) * 2003-03-28 2010-02-04 Fuji Film Mfg Europ B V RGD-angereicherte, gelatine-ähnliche Proteine zur Verhinderung der Zelladhäsion
US20050123550A1 (en) * 2003-05-12 2005-06-09 Laurent Philippe E. Molecules enhancing dermal delivery of influenza vaccines
US7588774B2 (en) 2003-05-12 2009-09-15 Becton, Dickinson And Company Molecules enhancing dermal delivery of influenza vaccines
US8080642B2 (en) 2003-05-16 2011-12-20 Vical Incorporated Severe acute respiratory syndrome DNA compositions and methods of use
CN1218750C (zh) 2003-06-06 2005-09-14 长春生物制品研究所 皮内注射用重组乙型肝炎卡介苗联合疫苗及制备方法
US20050058703A1 (en) * 2003-08-01 2005-03-17 Chang Robert C. Gelatin capsules
JP2007501224A (ja) * 2003-08-05 2007-01-25 フジ フォト フィルム ビー．ブイ． 安定剤としての組換え又は合成ゼラチン様タンパク質の、凍結乾燥医薬組成物中の使用
US20060204511A1 (en) * 2003-08-05 2006-09-14 Bouwstra Jan B Use of recombinant or synthetic gelatin as stabiliser in vaccines
BRPI0417225A (pt) * 2003-12-05 2007-03-06 Becton Dickinson Co métodos de aumentar a resposta imune no compartimento intradérmico e compostos úteis nos referidos métodos
GB0403247D0 (en) * 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
US7709256B2 (en) 2004-04-28 2010-05-04 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US7771999B2 (en) * 2004-04-28 2010-08-10 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US7785806B2 (en) 2004-04-28 2010-08-31 Vaxdesign Corporation Method for determining the immunogenicity of an antigen
US8298824B2 (en) 2004-04-28 2012-10-30 Sanofi Pasteur Vaxdesign Corporation Methods of evaluating a test agent in a diseased cell model
US8071373B2 (en) 2004-04-28 2011-12-06 Sanofi Pasteur Vaxdesign Corp. Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)
US7785883B2 (en) 2004-04-28 2010-08-31 Vax Design Corp. Automatable artificial immune system (AIS)
US8030070B2 (en) * 2004-04-28 2011-10-04 Sanofi Pasteur Vaxdesign Corp. Artificial lymphoid tissue equivalent
US7855074B2 (en) 2004-04-28 2010-12-21 Vaxdesign Corp. Artificial immune system: methods for making and use
CA2583698C (en) * 2004-10-06 2014-12-02 Medimmune Vaccines, Inc. Refrigerator-temperature stable influenza vaccine compositions
DE602006015289D1 (de) 2005-02-23 2010-08-19 Fujifilm Mfg Europe Bv Nicht-glycosylierte rekombinante collagen-ähnliche polypeptide
WO2006107188A1 (en) 2005-04-06 2006-10-12 Fujifilm Manufacturing Europe B.V. A non-porous film for culturing cells
US8017152B2 (en) 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
EP1726299A3 (de) * 2005-05-27 2007-04-18 StratoSphere Pharma AB Kerne und Mikrokapsel zur parenteralen Verabreichung sowie Verfahren zu deren Herstellung
DE102005054943A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Verfahren zur Herstellung eines Hohlprofils auf Basis eines vernetzten, Gelatine enthaltenden Materials sowie Implantate in Form von Hohlprofilen
DE102005054937A1 (de) * 2005-11-17 2007-05-24 Gelita Ag Angiogenese förderndes Substrat
US8278094B2 (en) * 2005-12-14 2012-10-02 The Invention Science Fund I, Llc Bone semi-permeable device
US8900865B2 (en) * 2005-12-14 2014-12-02 The Invention Science Fund I, Llc Blood brain barrier device
US8682619B2 (en) * 2005-12-14 2014-03-25 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US8734823B2 (en) * 2005-12-14 2014-05-27 The Invention Science Fund I, Llc Device including altered microorganisms, and methods and systems of use
US20110183348A1 (en) * 2010-01-22 2011-07-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Compositions and methods for therapeutic delivery with microorganisms
US8198080B2 (en) * 2005-12-14 2012-06-12 The Invention Science Fund I, Llc Bone delivery device
US20110172826A1 (en) * 2005-12-14 2011-07-14 Amodei Dario G Device including altered microorganisms, and methods and systems of use
US9005944B2 (en) * 2005-12-14 2015-04-14 The Invention Science Fund I, Llc Bone cell delivery device
US9061075B2 (en) 2005-12-14 2015-06-23 The Invention Science Fund I, Llc Bone delivery device
US8003387B2 (en) 2005-12-21 2011-08-23 Sanofi Pasteur Vaxdesign Corp. In vitro germinal centers
AU2006330951B2 (en) * 2005-12-21 2012-04-05 Sanofi Pasteur Vaxdesign Corporation A porous membrane device that promotes the differentiation of monocytes into dendritic cells
EP1981338A2 (de) * 2006-01-13 2008-10-22 Advanced Bionutrition Corporation Produktionssystem mit kontinuierlicher sprühnebelaufnahme
EP2409714A1 (de) 2006-06-27 2012-01-25 Sanofi Pasteur VaxDesign Corporation Modelle für die Bewertung von Impfstoffen
EP1961411A1 (de) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. Zusammensetzung mit gesteuerter Freisetzung
EP1961414A1 (de) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung
US8198047B2 (en) 2007-02-21 2012-06-12 Fujifilm Manufacturing Europe B.V. RGD containing recombinant gelatin
WO2008133196A1 (ja) * 2007-04-19 2008-11-06 Fujifilm Corporation 再生医療用材料
DE102007024256A1 (de) * 2007-05-16 2008-11-20 Gelita Ag Gefäßstent
WO2009048661A1 (en) * 2007-07-16 2009-04-16 Vaxdesign Corporation Artificial tissue constructs comprising alveolar cells and methods for using the same
JP2010539159A (ja) * 2007-09-14 2010-12-16 フジフィルム・マニュファクチュアリング・ヨーロッパ・ベスローテン・フエンノートシャップ 多量体組換えタンパク質の高収率分泌
WO2009075329A1 (ja) * 2007-12-11 2009-06-18 Fujifilm Corporation 分解性を調整したゼラチン組成物
AU2008342194B2 (en) 2007-12-26 2014-03-20 Daiichi Sankyo Company, Limited Method of producing Japanese encephalitis vaccine stably storable over long time and use of the vaccine
EP2222270B1 (de) * 2007-12-26 2018-11-14 Mark A. Pinsky Collagenformulierungen für verbesserte hautpflege
JP2011518782A (ja) 2008-04-10 2011-06-30 フジフィルム・マニュファクチュアリング・ヨーロッパ・ベスローテン・フエンノートシャップ ヘパリン結合部位および／またはヘパラン硫酸結合部位を富化した組換えタンパク質
AU2009263249B2 (en) * 2008-06-26 2015-03-19 Nobelpharma Co., Ltd. Agent for regenerating tympanic membrane or external auditory canal
JP2011526510A (ja) * 2008-07-04 2011-10-13 フジフィルム・マニュファクチュアリング・ヨーロッパ・ベスローテン・フエンノートシャップ 医療用デバイスのコーティング方法
JP5237714B2 (ja) * 2008-07-29 2013-07-17 ＢｉｏＲＯＩＳ株式会社 細胞輸送用担体及びそれを使用した細胞の輸送方法
US20110182960A1 (en) * 2008-10-02 2011-07-28 Elisabeth Marianna Wilhelmina Maria Van Dongen Antimicrobial Coating
CH700138B1 (it) * 2008-12-19 2012-12-14 Ind Biomediche Insubri S A Matrice per impianto osseo e procedimento di preparazione della stessa.
US8551749B2 (en) 2009-04-23 2013-10-08 The Invention Science Fund I, Llc Device including bone cage and method for treatment of disease in a subject
JP2009173678A (ja) * 2009-04-30 2009-08-06 Nitta Gelatin Inc コラーゲンタンパク質からのエンドトキシン除去方法
JP5752033B2 (ja) * 2009-05-07 2015-07-22 富士フイルム株式会社 遺伝子組み換えゼラチンを含む血管新生誘導剤
EP2461679B1 (de) * 2009-07-28 2019-02-13 GE Healthcare Bio-Sciences Corp. Impfstoffstabilisator
CA2770986C (en) * 2009-08-13 2016-05-10 Bioenol S.R.L. Process for producing instantaneous cold soluble gelatin and product thereof
CN102625717B (zh) * 2009-09-04 2016-03-16 富士胶片株式会社 包含明胶的骨再生剂
EP2502939B1 (de) 2009-11-19 2016-01-27 Zhejiang University Unnatürliches collagen-artiges protein und seine verwendung
GB0921460D0 (en) 2009-12-08 2010-01-20 Fujifilm Mfg Europe Bv Anti-fibrotic hydrogel compositions
KR20130005279A (ko) * 2010-03-01 2013-01-15 후지필름 가부시키가이샤 생체 친화성을 갖는 고분자 블록과 세포로 이루어지는 세포 구조체
US8486013B2 (en) * 2010-03-18 2013-07-16 Biotronik Ag Balloon catheter having coating
GB201008404D0 (en) 2010-05-20 2010-07-07 Fujifilm Mfg Europe Bv Hemostatic compositions
EP2407184A3 (de) * 2010-07-16 2014-10-29 Biotronik AG Abluminal beschichtete Wirkstoff-freisetzende Stents mit einer formschlüssigen Schutzschicht
GB201014388D0 (en) 2010-08-31 2010-10-13 Fujifilm Mfg Europe Bv Biocompatible compositions for tissue augmentation
DK3095441T3 (da) * 2010-10-08 2021-01-11 Scherer Technologies Llc R P Hurtigt opløsende doseringsform af en oral vaccine under anvendelse af stivelse
GB201018044D0 (en) * 2010-10-26 2010-12-08 Fujifilm Mfg Europe Bv Non-natural gelatin-like proteins with enhanced functionality
CN102020712B (zh) * 2010-11-11 2013-05-29 北京东方红航天生物技术股份有限公司 一种可用于疫苗稳定剂的类人胶原蛋白及其生产方法
JP2012149062A (ja) * 2010-12-29 2012-08-09 Bios Ikagaku Kenkyusho:Kk ヒトコラーゲン含有化粧料
US8728487B2 (en) * 2011-01-20 2014-05-20 Hua Wu Attenuated live vaccine for prevention of porcine reproductive and respiratory syndrome
JP5847418B2 (ja) * 2011-03-30 2016-01-20 富士フイルム株式会社 細胞接着性タンパク質
BR112014002546A2 (pt) * 2011-08-03 2017-03-14 Lotus Tissue Repair Inc "colágeno 7, ou seu fragmento funcional, seus métodos de produção e de purificação, sua preparação purificada ou isolada, vetor, coleção de vetores, preparação isolada de células, cultura celular, e método para produção de uma célula adequada à expressão de colágeno 7"
GB201119182D0 (en) 2011-11-07 2011-12-21 Fujifilm Mfg Europe Bv Porous tissue scaffolds
GB201119173D0 (en) 2011-11-07 2011-12-21 Fujifilm Mfg Europe Bv Porous tissue scaffolds
CN104023752B (zh) * 2011-12-20 2017-09-08 诺维信公司 用于从蛋白质溶液中除去病毒的方法
BR112015005797A2 (pt) 2012-09-18 2017-08-08 Dsm Ip Assets Bv processo para a produção de gelatina
WO2014050908A1 (ja) 2012-09-26 2014-04-03 富士フイルム株式会社 ポリペプチド、足場組成物、軟骨組織修復用組成物、軟骨細胞培養用組成物及びグリコサミノグリカン産生促進用組成物
CN103263688B (zh) * 2013-05-10 2014-07-30 华东师范大学 一种明胶组合物及其制备方法和应用
CN103725622A (zh) * 2013-12-19 2014-04-16 西安巨子生物基因技术股份有限公司 一种转基因毕赤酵母基因工程菌及其构建方法与应用
CN107073165B (zh) * 2014-10-22 2020-02-18 富士胶片株式会社 微载体的调制方法、微载体及其应用
US9526768B2 (en) 2014-11-13 2016-12-27 Jennifer Mai Compositions for the treatment of cancer
NL2013880B1 (en) * 2014-11-26 2016-10-11 Rousselot B V Gelatin purification.
CN105061589B (zh) * 2015-08-26 2018-02-27 华南理工大学 一种重组人ⅰ型胶原蛋白及其固定化发酵生产的方法
DE102015121923A1 (de) * 2015-12-16 2017-06-22 Gelita Ag Gießmasse und Verfahren für die Herstellung von Gelatineprodukten
EP3447127A4 (de) 2016-04-21 2019-05-01 Fujifilm Manufacturing Europe B.V. Verfahren zur herstellung von poröser gelatinfolie, poröse gelatinfolie und verwendung davon
NL2017219B1 (en) * 2016-07-22 2018-01-30 Rousselot B V Low cross-linking gelatine
US11180541B2 (en) * 2017-09-28 2021-11-23 Geltor, Inc. Recombinant collagen and elastin molecules and uses thereof
CN107857812A (zh) * 2017-11-17 2018-03-30 杭州惠博士生物科技有限公司 一种同人源胶原蛋白氨基酸、基因序列及蛋白氨基酸的制备方法
WO2019103981A1 (en) * 2017-11-22 2019-05-31 Geltor Inc. Methods and systems for engineering collagen
EP3489314A1 (de) * 2017-11-23 2019-05-29 Rousselot B.V. Verfahren zur herstellung von gelatinehydrolysat mit niedrigem endotoxingehalt
CN111447925B (zh) 2017-12-08 2021-11-05 晨光生物科技集团股份有限公司 一种番茄红素微囊粉及其制备方法
US10988638B2 (en) * 2018-03-08 2021-04-27 Catalent U.K. Swindon Zydis Limited Process to reduce endotoxin in gelatin
AU2019242912B2 (en) 2018-03-28 2025-07-17 Board Of Regents, The University Of Texas System Identification of epigenetic alterations in DNA isolated from exosomes
JP7437385B2 (ja) * 2018-09-06 2024-02-22 バヴァリアン・ノルディック・アクティーゼルスカブ 保管が改善されたポックスウイルス組成物
AU2019361030B2 (en) * 2018-10-16 2025-08-21 Board Of Regents, The University Of Texas System Compositions for and methods of producing tumor organoids
DE102019202606A1 (de) * 2018-11-06 2020-05-07 Gelita Ag Rekombinante Herstellung eines Kollagenpeptidpräparates und dessen Verwendung
CN109504665B (zh) * 2018-11-22 2022-08-23 江西师范大学 一种提高鱼鳞明胶品性的方法
CN109503707A (zh) * 2018-11-22 2019-03-22 江西师范大学 一种提高鱼皮明胶品性的方法
DE102019207859A1 (de) * 2018-12-21 2020-06-25 Gelita Ag Synthetische und rekombinant hergestellte Kollagenpeptide mit biologischer Wirksamkeit
SG11202110982WA (en) * 2019-04-01 2021-10-28 Geltor Inc Topical formulations of recombinant collagens
WO2020210440A1 (en) 2019-04-12 2020-10-15 Geltor, Inc. Recombinant elastin and production thereof
JPWO2021066049A1 (de) * 2019-09-30 2021-04-08
DE102020210725A1 (de) 2019-10-31 2021-05-06 Gelita Ag Ernährungsphysiologisch optimiertes Kollagenpeptid
WO2021112254A1 (ja) * 2019-12-06 2021-06-10 ノーベルファーマ株式会社 鼓膜再生用ゼラチンスポンジの製造方法
CN111011756A (zh) * 2019-12-26 2020-04-17 江西省壹加壹贸易有限公司 一种可食用的农副产品及禽蛋类载体广告宣传涂层及方法
CN115298212A (zh) * 2020-01-24 2022-11-04 格尔托公司 无动物膳食胶原蛋白
DE102020205703A1 (de) 2020-05-06 2021-11-11 Gelita Ag Expression von Kollagenpeptid-Komponenten in prokaryotischen Systemen
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
CN113880940A (zh) * 2020-07-03 2022-01-04 江苏江山聚源生物技术有限公司 重组人源Ⅰ型胶原蛋白Ⅰα1x6、表达菌株及其应用
WO2022170114A1 (en) * 2021-02-05 2022-08-11 Modern Meadow, Inc. Skincare compositions and methods of use thereof
DE102021202830A1 (de) 2021-03-23 2022-09-29 Gelita Ag Rekombinantes Typ II-Kollagen zur therapeutischen Verwendung
JPWO2023095781A1 (de) * 2021-11-24 2023-06-01
DE102021214899A1 (de) 2021-12-22 2023-06-22 Gelita Ag Typ I-Kollagenpeptid zur therapeutischen Verwendung
EP4202035A1 (de) 2021-12-22 2023-06-28 Gelita AG Verbesserte expression von peptiden
US20250074969A1 (en) * 2022-01-14 2025-03-06 Cambrium Gmbh Novel Recombinant Collagen Polypeptides and Molecules
CN114316029B (zh) * 2022-01-27 2023-06-27 西安巨子生物基因技术股份有限公司 透皮吸收性肽及通过该肽的重复构建的重组胶原蛋白
TWI856287B (zh) * 2022-02-11 2024-09-21 國立臺灣科技大學 可溶解感溫型的微載體、其製備方法及其使用方法
US20250248429A1 (en) * 2022-04-14 2025-08-07 Omeat Inc. Systems and methods of preparing cultivated meat and meat analogs from plant-based proteins
CN114940712B (zh) * 2022-06-01 2023-12-26 山西锦波生物医药股份有限公司 一种生物合成人体结构性材料的制备方法
CN115960268B (zh) * 2022-12-30 2025-03-11 广州栋方生物科技股份有限公司 一种胶原蛋白-芋螺肽融合蛋白及其制备方法和应用
TW202446787A (zh) * 2023-05-17 2024-12-01 美商Ｈｔｌ生物科技創新股份有限公司 膠原蛋白生產程序
DE102023205346A1 (de) 2023-06-07 2024-12-12 Gelita Ag Verzehrbare Produkte mit rekombinant hergestelltem Kollagen
WO2025111688A1 (en) * 2023-12-01 2025-06-05 Liven Proteins Corp. Collagen-derived polypeptides
DE102024112560A1 (de) 2024-05-03 2025-11-06 Gelita Ag Verfahren zur Herstellung einer gelierenden Kollagenkomponente
CN119708209B (zh) * 2025-03-04 2025-07-01 英特菲尔(成都)生物制品有限责任公司 一种具有低温自组装特性的重组ⅰ型胶原蛋白及其制备方法与应用

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US987292A (en) 1910-05-04 1911-03-21 William T Anderson Tire.
US4147772A (en) 1976-02-03 1979-04-03 Merck & Co., Inc. Vaccine stabilizer
JPS545048A (en) * 1977-06-12 1979-01-16 Nippon Baruku Yakuhin Kk Production of gellatin hydrolysate
US4215051A (en) 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
US4337242A (en) 1980-02-05 1982-06-29 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
US4338335A (en) 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
NL8200523A (nl) 1982-02-11 1983-09-01 Univ Leiden Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
US4736866B1 (en) 1984-06-22 1988-04-12 Transgenic non-human mammals
US4855231A (en) 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
JPH074232B2 (ja) 1984-12-10 1995-01-25 モンサントコンパニー バチルスチユウリンゲンシス結晶蛋白遺伝子の植物上での集落形成能を有する微生物への挿入及びその用途
DE3687364T2 (de) 1985-04-30 1993-07-15 Monsanto Co Pflanzenkolonisierende mikroorganismen, die das bacillus thuringiensis-toxingen als chromosomeinsetzung enthalten.
TR27832A (tr) 1987-04-29 1995-08-31 Monsanto Co Zararli ucucu hasarata mukavim bitkiler.
JPS63307827A (ja) 1987-06-08 1988-12-15 Kitasato Inst:The 安定化された生ウイルスワクチンおよびその製造法
US5464764A (en) 1989-08-22 1995-11-07 University Of Utah Research Foundation Positive-negative selection methods and vectors
US5614396A (en) 1990-06-14 1997-03-25 Baylor College Of Medicine Methods for the genetic modification of endogenous genes in animal cells by homologous recombination
EP0550506B1 (de) 1990-09-05 2002-11-20 The Heart Research Institute Limited Chemotaktische faktoren
US5593859A (en) 1991-10-23 1997-01-14 Thomas Jefferson University Synthesis of human procollagens and collagens in recombinant DNA systems
CA2121698C (en) * 1991-10-23 2010-05-18 Darwin J. Prockop Synthesis of human procollagens and collagens in recombinant dna systems
FR2685347A1 (fr) * 1991-12-23 1993-06-25 Univ Pasteur Procede biotechnologique d'obtention et de production microbienne d'oligomeres peptidiques comme substituts de la gelatine.
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
AU2088992A (en) 1992-05-05 1993-11-11 Research Foundation For Microbial Diseases Of Osaka University, The Stabilized live vaccine
JPH06234659A (ja) * 1992-05-05 1994-08-23 Handai Biseibutsubiyou Kenkyukai 安定化生ワクチン
US5981505A (en) * 1993-01-26 1999-11-09 The Trustees Of The University Of Pennsylvania Compositions and methods for delivery of genetic material
GB9316883D0 (en) 1993-08-13 1993-09-29 Univ Leeds Production of heterologous peptices
US5362865A (en) 1993-09-02 1994-11-08 Monsanto Company Enhanced expression in plants using non-translated leader sequences
US6713662B1 (en) * 1994-07-27 2004-03-30 Pharming Intellectual Property B.V. Production of collagen in the milk of transgenic mammals
US5710252A (en) * 1995-02-03 1998-01-20 Eastman Kodak Company Method for recombinant yeast expression and isolation of water-soluble collagen-type polypeptides
WO1997004123A1 (en) * 1995-07-19 1997-02-06 Gel Tech Group Inc. Collagen compound production in plants
IL124437A0 (en) * 1995-11-13 1998-12-06 Fibrogen Inc Type IX collagen and chimeras
US5928922A (en) * 1996-04-10 1999-07-27 Academy Of Finland α2 subunit of prolyl-4-hydroxylase, nucleic acid sequences encoding such subunit and methods for producing the same
AU3056697A (en) * 1996-04-12 1997-11-07 Academy Of Finland Synthesis of human procollagens and collagens in recombinant dna systems
US5824838A (en) 1996-05-09 1998-10-20 Cedars-Sinai Medical Center Transgenic mouse model for pituitary disorders associated with LIF overexpression and/or GH underexpression, and its use for testing therapeutic drugs for the conditions
US5821089A (en) * 1996-06-03 1998-10-13 Gruskin; Elliott A. Amino acid modified polypeptides
FR2757874B1 (fr) * 1996-12-17 2003-04-25 Biocem Collagenes recombinants et proteines derivees produits par les plantes, leurs procedes d'obtention et leurs utilisations
US6210683B1 (en) * 1997-09-05 2001-04-03 Merck & Co., Inc. Stabilizers containing recombinant human serum albumin for live virus vaccines
NL1007908C2 (nl) * 1997-12-24 1999-06-25 Fuji Photo Film Bv Zilverhalide-emulsies met recombinant collageen die geschikt zijn voor fotografische toediening alsmede de bereiding daarvan.
US6428978B1 (en) * 1998-05-08 2002-08-06 Cohesion Technologies, Inc. Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
US6462013B1 (en) 1998-06-26 2002-10-08 National Starch And Chemical Investment Holding Corporation Isotropic liquid detergent comprising ethylenically unsaturated acid monomer-C1 to C24 chain transfer agent polymerization product
DE69940802D1 (de) 1998-12-23 2009-06-10 Fujifilm Mfg Europe Bv Silberhalogenidemulsionen, die rekombinante gelatineartige Proteine enthalten
ATE405647T1 (de) * 1999-11-12 2008-09-15 Fibrogen Inc Rekombinantes gelatin in impstoffen
US6992172B1 (en) * 1999-11-12 2006-01-31 Fibrogen, Inc. Recombinant gelatins
CA2399371A1 (en) * 1999-11-12 2001-05-17 Fibrogen, Inc. Animal collagens and gelatins
US6465207B1 (en) * 2000-11-03 2002-10-15 Cytologix Corporation Silver-based staining processes employing non-gelling gelatin

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