HUT77049A - Katepszin-02-fehérjék, -nukleinsavak és -ellenanyagok - Google Patents

Katepszin-02-fehérjék, -nukleinsavak és -ellenanyagok

Info

Publication number
HUT77049A
HUT77049A HU9701942A HU9701942A HUT77049A HU T77049 A HUT77049 A HU T77049A HU 9701942 A HU9701942 A HU 9701942A HU 9701942 A HU9701942 A HU 9701942A HU T77049 A HUT77049 A HU T77049A
Authority
HU
Hungary
Prior art keywords
cathepsin
protease
antibodies
proteins
relates
Prior art date
Application number
HU9701942A
Other languages
English (en)
Other versions
HU220960B1 (hu
Inventor
Dieter Brömme
Kathleen Okamoto
Original Assignee
Arris Pharmaceutical Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26987129&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUT77049(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/330,121 external-priority patent/US5736357A/en
Application filed by Arris Pharmaceutical Corporation filed Critical Arris Pharmaceutical Corporation
Publication of HUT77049A publication Critical patent/HUT77049A/hu
Publication of HU220960B1 publication Critical patent/HU220960B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
HU9701942A 1994-10-27 1995-10-26 Enzimatikusan aktív rekombináns katepszin-fehérjék HU220960B1 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/330,121 US5736357A (en) 1994-10-27 1994-10-27 Cathespin O protease
US08/536,861 US6544767B1 (en) 1994-10-27 1995-10-02 Cathespin O2 protease
PCT/US1995/013820 WO1996013523A1 (en) 1994-10-27 1995-10-26 Cathepsin o2 protease

Publications (2)

Publication Number Publication Date
HUT77049A true HUT77049A (hu) 1998-03-02
HU220960B1 HU220960B1 (hu) 2002-07-29

Family

ID=26987129

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9701942A HU220960B1 (hu) 1994-10-27 1995-10-26 Enzimatikusan aktív rekombináns katepszin-fehérjék

Country Status (15)

Country Link
US (2) US6544767B1 (hu)
EP (1) EP0783527B1 (hu)
JP (1) JP3670666B2 (hu)
KR (1) KR100473219B1 (hu)
CN (1) CN1148382C (hu)
AT (1) ATE317441T1 (hu)
AU (1) AU711810B2 (hu)
CA (1) CA2203765C (hu)
DE (1) DE69534778T2 (hu)
ES (1) ES2256849T3 (hu)
FI (1) FI971777A0 (hu)
HU (1) HU220960B1 (hu)
NO (1) NO971875L (hu)
NZ (1) NZ296003A (hu)
WO (1) WO1996013523A1 (hu)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403304B1 (en) 1993-04-06 2002-06-11 Forsyth Dental Infirmary For Children Human osteoclast-specific and -related DNA sequences
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
US6274336B1 (en) 1995-10-30 2001-08-14 Smithkline Beecham Corporation Method of inhibiting cathepsin K
SK56798A3 (en) 1995-10-30 1998-12-02 Smithkline Beecham Corp Protease inhibitors, pharmaceutical composition containing them and their use
EP0812916A3 (en) * 1996-06-14 1998-12-09 Smithkline Beecham Corporation Cathepsin k gene
WO1998000716A1 (en) * 1996-07-03 1998-01-08 Novadx, Inc. Method for detecting degenerative bone disease
GB9701888D0 (en) * 1997-01-30 1997-03-19 Ciba Geigy Ag Novel methods
US5948669A (en) * 1997-02-26 1999-09-07 Smithkline Beecham Corporation Rat cathepsin K polynucleotide and polypeptide sequence
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US6346373B1 (en) * 1999-05-05 2002-02-12 Merck Frosst Canada & Co., Whole cell assay for cathepsin K activity
AU6199100A (en) * 1999-06-25 2001-01-31 Hybritech Incorporated Cloning and expressing of human cathepsin k in mammalian cells
JP2003513972A (ja) 1999-11-10 2003-04-15 スミスクライン・ビーチャム・コーポレイション プロテアーゼ阻害剤
US6596715B1 (en) 1999-11-10 2003-07-22 Smithkline Beecham Corporation Protease inhibitors
AU1474801A (en) 1999-11-10 2001-06-06 Smithkline Beecham Corporation Protease inhibitors
CA2397194C (en) 2000-01-20 2011-05-17 Mark E. Duggan Alpha v integrin receptor antagonists
US7071184B2 (en) 2000-03-21 2006-07-04 Smithkline Beecham Corporation Protease inhibitors
EP1387886A2 (en) * 2000-10-18 2004-02-11 Incyte Genomics, Inc. Proteases
CA2489736A1 (en) * 2002-06-17 2003-12-24 Nichirei Corporation Novel cathepsin l-like cysteine protease originating in pink shrimp
WO2004000838A1 (en) * 2002-06-24 2003-12-31 Axys Pharmaceuticals, Inc. Peptidic compounds as cysteine protease inhibitors
EP1651238A1 (en) * 2003-07-21 2006-05-03 Novartis AG Combinations of a cathepsin k inhibitor and a bisphophonate in the treatment of bone metastasis, tumor growth and tumor-induced bone loss
CN1839114A (zh) 2003-08-21 2006-09-27 默克弗罗斯特加拿大有限公司 组织蛋白酶半胱氨酸蛋白酶抑制剂
CA2539076A1 (en) * 2003-09-23 2005-03-31 Merck Frosst Canada Ltd. Whole cell assay for inhibitors of cathepsin k
WO2005093421A1 (de) * 2004-03-10 2005-10-06 Biovendor Laboratory Medicine, Inc. Enzymimmunoassay zur bestimmung von cathepsin k
US7029902B2 (en) * 2004-03-26 2006-04-18 Applera Corporation Isolated monkey cathepsin S proteins, nucleic acid molecules encoding monkey cathepsin S proteins, and uses thereof
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
AU2013202011C1 (en) * 2008-03-06 2015-10-01 Halozyme, Inc. In vivo temporal control of activatable matrix-degrading enzymes
US8901144B2 (en) 2013-02-07 2014-12-02 Scifluor Life Sciences, Llc Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
DK2953948T3 (en) 2013-02-07 2017-12-18 Scifluor Life Sciences Inc FLUORINATED INTEGRIN ANTAGONISTS
RU2016146826A (ru) 2014-05-30 2018-07-04 Пфайзер Инк. Производные карбонитрилов как селективные модуляторы андрогенового рецептора
AU2016219906B2 (en) 2015-02-19 2020-10-01 Scifluor Life Sciences, Inc. Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
WO1997047642A1 (en) 1996-06-14 1997-12-18 Smithkline Beecham Corporation Cathepsin k gene

Also Published As

Publication number Publication date
AU711810B2 (en) 1999-10-21
WO1996013523A1 (en) 1996-05-09
JP3670666B2 (ja) 2005-07-13
NZ296003A (en) 1999-10-28
DE69534778D1 (en) 2006-04-20
FI971777A (fi) 1997-04-25
NO971875L (no) 1997-06-12
KR100473219B1 (ko) 2005-05-16
EP0783527A1 (en) 1997-07-16
CA2203765C (en) 2002-04-23
EP0783527A4 (en) 1998-12-02
NO971875D0 (no) 1997-04-23
FI971777A0 (fi) 1997-04-25
JPH10512740A (ja) 1998-12-08
AU3968895A (en) 1996-05-23
CN1148382C (zh) 2004-05-05
ES2256849T3 (es) 2006-07-16
CA2203765A1 (en) 1996-05-09
EP0783527B1 (en) 2006-02-08
CN1170415A (zh) 1998-01-14
US6544767B1 (en) 2003-04-08
US20030175937A1 (en) 2003-09-18
ATE317441T1 (de) 2006-02-15
HU220960B1 (hu) 2002-07-29
KR970707153A (ko) 1997-12-01
DE69534778T2 (de) 2006-08-17

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees