|
US5183884A
(en)
|
1989-12-01 |
1993-02-02 |
United States Of America |
Dna segment encoding a gene for a receptor related to the epidermal growth factor receptor
|
|
US6639061B1
(en)
|
1999-07-07 |
2003-10-28 |
Isis Pharmaceuticals, Inc. |
C3′-methylene hydrogen phosphonate oligomers and related compounds
|
|
US5804396A
(en)
|
1994-10-12 |
1998-09-08 |
Sugen, Inc. |
Assay for agents active in proliferative disorders
|
|
WO1996014864A1
(en)
|
1994-11-09 |
1996-05-23 |
The Regents Of The University Of California |
Immunoliposomes that optimize internalization into target cells
|
|
PT896586E
(pt)
|
1996-03-27 |
2007-01-31 |
Genentech Inc |
Anticorpos de erbb3
|
|
US5968511A
(en)
|
1996-03-27 |
1999-10-19 |
Genentech, Inc. |
ErbB3 antibodies
|
|
CA2589421C
(en)
|
1996-03-27 |
2012-12-18 |
Genentech, Inc. |
Erbb3 antibodies
|
|
US5922845A
(en)
|
1996-07-11 |
1999-07-13 |
Medarex, Inc. |
Therapeutic multispecific compounds comprised of anti-Fcα receptor antibodies
|
|
DE69740038D1
(enExample)
|
1996-07-12 |
2010-12-16 |
Genentech Inc |
|
|
US20020002276A1
(en)
|
1997-02-10 |
2002-01-03 |
Genentech, Inc. |
Chimeric heteromultimer adhesins
|
|
WO1999047677A2
(en)
|
1998-03-17 |
1999-09-23 |
Genentech, Inc. |
Polypeptides homologous to vegf and bmp1
|
|
US6723694B1
(en)
|
1997-05-21 |
2004-04-20 |
The Children's Medical Center Corp. |
Short peptides which selectively modulate intracellular signalling
|
|
US6416168B1
(en)
|
1997-07-15 |
2002-07-09 |
Silverbrook Research Pty Ltd |
Pump action refill ink jet printing mechanism
|
|
ZA9811162B
(en)
|
1997-12-12 |
2000-06-07 |
Genentech Inc |
Treatment with anti-ERBB2 antibodies.
|
|
US20010023241A1
(en)
|
1998-02-04 |
2001-09-20 |
Sliwkowski Mark X. |
Use of heregulin as a growth factor
|
|
AU2003203831B2
(en)
|
1998-02-04 |
2006-08-10 |
Genentech, Inc. |
Use of heregulin as an epithelial cell growth factor
|
|
DE69920405T2
(de)
|
1998-02-04 |
2006-01-05 |
Genentech, Inc., South San Francisco |
Verwendung des heregulins als epithelzellenwachstumsfaktor
|
|
US6417168B1
(en)
|
1998-03-04 |
2002-07-09 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of treating tumors
|
|
JP4334141B2
(ja)
|
1998-04-20 |
2009-09-30 |
グリカート バイオテクノロジー アクチェンゲゼルシャフト |
抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作
|
|
BR9910511A
(pt)
|
1998-05-15 |
2001-11-20 |
Imclone Systems Inc |
Tratamento de tumores humanos com radiação einibidores de tirosina cinases receptoras de fatorde crescimento
|
|
AU2004200705A1
(en)
|
1998-05-15 |
2004-03-18 |
Imclone Systems Incorporated |
Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases
|
|
ZA200007412B
(en)
|
1998-05-15 |
2002-03-12 |
Imclone Systems Inc |
Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases.
|
|
WO2000027426A1
(en)
|
1998-11-07 |
2000-05-18 |
Genentech, Inc. |
Method for enhancing proliferation of inner ear hair cells using ligands for her2 and/or her3 receptors
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
EP1169352A4
(en)
*
|
1999-04-14 |
2005-05-04 |
Smithkline Beecham Corp |
ANTIBODY AGAINST THE ERYTHROPOIETIN RECEPTOR
|
|
US7534866B2
(en)
|
2005-10-19 |
2009-05-19 |
Ibc Pharmaceuticals, Inc. |
Methods and compositions for generating bioactive assemblies of increased complexity and uses
|
|
US6710186B2
(en)
|
1999-06-14 |
2004-03-23 |
Wisconsin Alumni Research Foundation |
Oligomers and polymers of di-substituted cyclic imino carboxylic acids
|
|
AUPQ105799A0
(en)
|
1999-06-18 |
1999-07-08 |
Victor Chang Cardiac Research Institute, The |
Cell growth inhibition
|
|
GEP20104998B
(en)
|
1999-06-25 |
2010-06-10 |
Genentech Inc |
Humanized antibody which binds erbb2 and blocks activation by ligand receptor of erbb2 (variants) and use of the composition comprising these antibodies methods for treating cancer
|
|
US6949245B1
(en)
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
EP2977063A1
(en)
|
1999-06-25 |
2016-01-27 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
EP2111870A1
(en)
|
1999-08-27 |
2009-10-28 |
Genentech, Inc. |
Dosages for treatment of anti-erbB2 antibodies
|
|
US7732157B1
(en)
|
1999-09-30 |
2010-06-08 |
Tumor Biology Investment Group |
Soluble epidermal growth factor receptor-like proteins and their uses in cancer detection methods
|
|
US7390632B2
(en)
|
1999-09-30 |
2008-06-24 |
Tumor Biology Investment Group, Inc. |
Soluble ErbB3 receptor isoforms
|
|
US7651703B2
(en)
|
1999-10-15 |
2010-01-26 |
Genentech, Inc. |
Injection vehicle for polymer-based formulations
|
|
CA2397417A1
(en)
|
2000-01-12 |
2001-07-19 |
Sarah S. Bacus |
Method for quantitating a protein by image analysis
|
|
PT1255558E
(pt)
|
2000-02-16 |
2006-11-30 |
Genentech Inc |
Anticorpos anti-april e células hibridoma
|
|
US6632979B2
(en)
|
2000-03-16 |
2003-10-14 |
Genentech, Inc. |
Rodent HER2 tumor model
|
|
US7097840B2
(en)
|
2000-03-16 |
2006-08-29 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
|
DK1272647T3
(en)
|
2000-04-11 |
2014-12-15 |
Genentech Inc |
Multivalent antibodies and uses thereof
|
|
AU2007216733A1
(en)
|
2000-04-11 |
2007-09-27 |
Genentech, Inc. |
Multivalent antibodies and uses therefor
|
|
FR2807767B1
(fr)
|
2000-04-12 |
2005-01-14 |
Lab Francais Du Fractionnement |
Anticorps monoclonaux anti-d
|
|
US6277640B1
(en)
|
2000-07-31 |
2001-08-21 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of Her-3 expression
|
|
US7469441B2
(en)
|
2000-11-24 |
2008-12-30 |
Carl Freudenberg Kg |
Floor mop
|
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
AU2008200400B2
(en)
|
2001-01-17 |
2012-06-07 |
Aptevo Research And Development Llc |
Binding domain-immunoglobulin fusion proteins
|
|
EP1228766A1
(en)
|
2001-01-31 |
2002-08-07 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
PYK2 phosphorylation by HER3 induces tumor invasion
|
|
KR100890088B1
(ko)
|
2001-02-12 |
2009-03-24 |
메다렉스, 인코포레이티드 |
Ｆｃ 알파 수용체（ＣＤ８９）에 대한 인간 모노클로날 항체
|
|
AU2002257132A1
(en)
|
2001-04-06 |
2002-10-21 |
The Trustees Of The University Of Pennsylvania |
Erbb interface peptidomimetics and methods of use thereof
|
|
WO2002087618A1
(en)
|
2001-04-27 |
2002-11-07 |
Takeda Chemical Industries, Ltd. |
Preventive/therapeutic method for cancer
|
|
JP2005505749A
(ja)
|
2001-05-21 |
2005-02-24 |
アクララ バイオサイエンシーズ， インコーポレイテッド |
タンパク質を分析するための方法および組成物
|
|
US7745398B2
(en)
|
2001-05-31 |
2010-06-29 |
Tumor Biology Investment Group, Inc. |
Soluble ErbB3 and treatment of cancer
|
|
US7744882B2
(en)
|
2001-05-31 |
2010-06-29 |
Tumor Biology Investment Group, Inc. |
Soluble ErbB3 methods of detection and antibodies
|
|
IL159177A0
(en)
|
2001-06-20 |
2004-06-01 |
Prochon Biotech Ltd |
Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
|
|
US7276658B2
(en)
|
2001-06-21 |
2007-10-02 |
Akzo Nobel N.V. |
Manufacturing a solar cell foil connected in series via a temporary substrate
|
|
US7125680B2
(en)
|
2001-07-27 |
2006-10-24 |
The Regents Of The University Of California |
Methods and materials for characterizing and modulating interaction between heregulin and HER3
|
|
DE10137374A1
(de)
|
2001-07-31 |
2003-02-27 |
Ipk Inst Fuer Pflanzengenetik |
Verfahren zur Herstellung von Arachidonsäure in transgenen Organismen
|
|
WO2003012072A2
(en)
|
2001-08-03 |
2003-02-13 |
The Trustees Of The University Of Pennsylvania |
Monoclonal antibodies to activated erbb family members and methods of use thereof
|
|
EP1283053A1
(en)
|
2001-08-09 |
2003-02-12 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Inhibitors of HER3 activity
|
|
AU2008200654B2
(en)
|
2001-08-09 |
2010-04-29 |
Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. |
Inhibitors of HER3 activity
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
JP4132912B2
(ja)
|
2002-03-26 |
2008-08-13 |
日東電工株式会社 |
ゲル電解質とその製造方法とその利用
|
|
CN100424175C
(zh)
|
2002-03-26 |
2008-10-08 |
上海泽生科技开发有限公司 |
ErbB-3 用于肿瘤治疗的方法和组合物
|
|
US7332585B2
(en)
|
2002-04-05 |
2008-02-19 |
The Regents Of The California University |
Bispecific single chain Fv antibody molecules and methods of use thereof
|
|
US7332580B2
(en)
|
2002-04-05 |
2008-02-19 |
The Regents Of The University Of California |
Bispecific single chain Fv antibody molecules and methods of use thereof
|
|
JP4319979B2
(ja)
|
2002-04-26 |
2009-08-26 |
ジェネンテック・インコーポレーテッド |
タンパク質の非アフィニティ精製
|
|
US20040229380A1
(en)
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
ErbB heterodimers as biomarkers
|
|
US20040229299A1
(en)
|
2002-05-21 |
2004-11-18 |
Badal M. Youssouf |
Intracellular complexes as biomarkers
|
|
US20040229294A1
(en)
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
ErbB surface receptor complexes as biomarkers
|
|
US20040229293A1
(en)
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
Surface receptor complexes as biomarkers
|
|
US20040132097A1
(en)
|
2002-06-19 |
2004-07-08 |
Bacus Sarah S. |
Method for predicting response to epidermal growth factor receptor-directed therapy
|
|
EP2263691B1
(en)
|
2002-07-15 |
2012-08-29 |
F.Hoffmann-La Roche Ag |
Treatment of cancer with the recombinant humanized monoclonal anti-erbb2 antibody 2C4 (rhuMAb 2C4)
|
|
EP1540347B1
(en)
|
2002-07-25 |
2009-09-09 |
Aclara BioSciences, Inc. |
Detecting receptor oligomerization
|
|
GB0225282D0
(en)
|
2002-10-31 |
2002-12-11 |
Astrazeneca Ab |
assay
|
|
AU2004205684A1
(en)
|
2003-01-23 |
2004-08-05 |
Genentech, Inc. |
Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
|
|
AU2004226162A1
(en)
|
2003-04-04 |
2004-10-14 |
Universite De Lausanne |
Peptabody for cancer treatment
|
|
US7189694B2
(en)
|
2003-04-18 |
2007-03-13 |
University Of Florida Research Foundation, Inc. |
Inhibitors of autophosphorylation protein kinases
|
|
KR101126560B1
(ko)
|
2003-05-30 |
2012-04-05 |
도꾜 다이가꾸 |
약제 반응 예측 방법
|
|
EP2367008A3
(en)
|
2003-06-06 |
2014-12-24 |
Genentech, Inc. |
Modulating the interaction between HGF beta chain and C-Met
|
|
US20040254108A1
(en)
|
2003-06-13 |
2004-12-16 |
Jing Ma |
Preparation and application of anti-tumor bifunctional fusion proteins
|
|
CA2528595A1
(en)
|
2003-06-13 |
2005-01-06 |
Oncomax Acquisition Corp. |
Preparation and application of anti-tumor bifunctional fusion proteins
|
|
US20050232931A1
(en)
|
2003-06-13 |
2005-10-20 |
Oncomax Acquisition Corp. |
Preparation and application of anti-tumor bifunctional fusion proteins
|
|
US6836094B1
(en)
|
2003-07-01 |
2004-12-28 |
International Truck Intellectual Property Company, Llc |
Motor vehicle battery disconnect switch circuits
|
|
US7531649B2
(en)
|
2003-07-18 |
2009-05-12 |
The Regents Of The University Of California |
Aptamers to human epidermal growth factor receptor-3
|
|
PL3095793T3
(pl)
|
2003-07-28 |
2020-09-07 |
Genentech, Inc. |
Redukcja wycieku białka A w trakcie chromatografii powinowactwa z białkiem A
|
|
EP1651095A4
(en)
|
2003-08-05 |
2008-10-08 |
Euro Celtique Sa |
ErbB RECEPTOR PROCESS AND SETS FOR MONITORING CHEMOTHERAPY RESISTANCE
|
|
JP4818917B2
(ja)
|
2003-08-08 |
2011-11-16 |
イミューノメディクス、インコーポレイテッド |
腫瘍および罹患細胞のアポトーシスを誘発するための二重特異性抗体
|
|
AU2004267420A1
(en)
|
2003-08-11 |
2005-03-03 |
Monogram Biosciences, Inc. |
Detecting and profiling molecular complexes
|
|
US8399618B2
(en)
|
2004-10-21 |
2013-03-19 |
Xencor, Inc. |
Immunoglobulin insertions, deletions, and substitutions
|
|
US20070148170A1
(en)
|
2005-10-03 |
2007-06-28 |
Desjarlais John R |
Fc Variants With Optimized Fc Receptor Binding Properties
|
|
EP1681983A4
(en)
|
2003-10-14 |
2008-12-10 |
Monogram Biosciences Inc |
RECEPTOR TYROSINE KINASE SIGNAL PATH ANALYSIS FOR DIAGNOSIS AND THERAPY
|
|
US20050130246A1
(en)
|
2003-10-27 |
2005-06-16 |
Hossein Salimi-Moosavi |
Detecting human anti-therapeutic antibodies
|
|
JP2007510708A
(ja)
|
2003-11-06 |
2007-04-26 |
ファイザー・プロダクツ・インク |
癌の治療における選択的ｅｒｂＢ２阻害剤／抗ｅｒｂＢ抗体の組合せ
|
|
US7754441B2
(en)
|
2003-11-17 |
2010-07-13 |
Genentech, Inc. |
Compositions and methods for the treatment of tumor of hematopoietic origin
|
|
US7235641B2
(en)
|
2003-12-22 |
2007-06-26 |
Micromet Ag |
Bispecific antibodies
|
|
JP4658967B2
(ja)
|
2003-12-24 |
2011-03-23 |
ジェネンテック， インコーポレイテッド |
造血系起源の腫瘍の治療のための組成物と方法
|
|
US8323987B2
(en)
|
2004-02-17 |
2012-12-04 |
The University Of North Carolina At Chapel Hill |
Modulation of epidermal growth factor heterodimer activity
|
|
US7906624B2
(en)
|
2004-02-20 |
2011-03-15 |
The Trustees Of The University Of Pennsylvania |
Binding peptidomimetics and uses of the same
|
|
EP1796711A2
(en)
|
2004-04-22 |
2007-06-20 |
Oregon Health and Science University |
Herstatin or intron 8-encoded domain thereof for modulating signaling mediated by igf-1 receptor and erbb receptors
|
|
WO2005117973A2
(en)
|
2004-05-05 |
2005-12-15 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents for modulating biological activity
|
|
MXPA06014065A
(es)
|
2004-06-01 |
2007-01-31 |
Genentech Inc |
Conjugados de droga-anticuerpo y metodos.
|
|
KR20120133403A
(ko)
|
2004-06-01 |
2012-12-10 |
도만티스 리미티드 |
증강된 혈청 반감기를 가지는 이특이성 융합 항체
|
|
SV2006002143A
(es)
|
2004-06-16 |
2006-01-26 |
Genentech Inc |
Uso de un anticuerpo para el tratamiento del cancer resistente al platino
|
|
WO2006000034A1
(en)
|
2004-06-24 |
2006-01-05 |
The Walter And Eliza Hall Institute Of Medical Research |
Conjugates and therapeutic uses thereof
|
|
AU2005287404B2
(en)
|
2004-07-22 |
2009-05-07 |
Genentech, Inc. |
HER2 antibody composition
|
|
ES2579805T3
(es)
|
2004-09-23 |
2016-08-16 |
Genentech, Inc. |
Anticuerpos y conjugados modificados por ingeniería genética con cisteína
|
|
US20100111856A1
(en)
|
2004-09-23 |
2010-05-06 |
Herman Gill |
Zirconium-radiolabeled, cysteine engineered antibody conjugates
|
|
AU2005294347A1
(en)
|
2004-10-05 |
2006-04-20 |
Oregon Health And Science University |
Compositions and methods for treating disease
|
|
BRPI0517837A
(pt)
|
2004-11-12 |
2008-10-21 |
Xencor Inc |
variantes fc com ligação alterada a fcrn
|
|
NZ555566A
(en)
|
2004-11-22 |
2009-12-24 |
Vertex Pharma |
Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases
|
|
US7947839B2
(en)
|
2004-12-01 |
2011-05-24 |
Genentech, Inc. |
Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use
|
|
ES2356830T3
(es)
*
|
2004-12-03 |
2011-04-13 |
Schering Corporation |
Biomarcadores para preselección de pacientes para terapia de anti-igf-1r.
|
|
AU2005314127A1
(en)
|
2004-12-07 |
2006-06-15 |
Genentech, Inc. |
Selecting patients for therapy with a HER inhibitor
|
|
CA2601700A1
(en)
|
2004-12-21 |
2006-06-29 |
Cell Signaling Technology, Inc. |
Protein phosphorylation in egfr-signaling pathways
|
|
US7807789B2
(en)
|
2004-12-21 |
2010-10-05 |
Cell Signaling Technology, Inc. |
Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
|
|
AU2006204459B2
(en)
|
2005-01-05 |
2012-11-01 |
F-Star Therapeutics Limited |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
|
CN101365712A
(zh)
|
2005-01-11 |
2009-02-11 |
莫勒丘尔洛吉克斯有限公司 |
Pan-HER拮抗剂及其使用方法
|
|
MX2007008768A
(es)
|
2005-01-21 |
2007-10-19 |
Genentech Inc |
Dosificacion fija de anticuerpos her.
|
|
WO2006084018A2
(en)
|
2005-02-02 |
2006-08-10 |
Monogram Biosciences, Inc. |
Methods for determining responsiveness to cancer therapy
|
|
EP2402374A1
(en)
|
2005-02-07 |
2012-01-04 |
GlycArt Biotechnology AG |
Antigen binding molecules that bind EGFR, vectors encoding same, and uses thereof
|
|
US7718626B2
(en)
|
2005-02-17 |
2010-05-18 |
University Of Maryland, Baltimore |
ErbB3 binding protein compositions and methods of use
|
|
CN103251946A
(zh)
|
2005-02-23 |
2013-08-21 |
健泰科生物技术公司 |
使用her二聚化抑制剂在癌症患者中延长病情进展前时间或存活
|
|
WO2006091209A2
(en)
|
2005-02-23 |
2006-08-31 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents for modulating biological activity
|
|
CA2600375A1
(en)
|
2005-03-07 |
2006-09-14 |
Targeted Molecular Diagnostics, Llc |
Tyrosine kinase inhibitor compositions and methods for manufacturing and using them in the treatment of disease
|
|
TW200642695A
(en)
|
2005-03-08 |
2006-12-16 |
Genentech Inc |
Methods for identifying tumors responsive to treatment with her dimerization inhibitors (HDIs)
|
|
CN101484182B
(zh)
|
2005-04-06 |
2014-06-11 |
Ibc药品公司 |
由同二聚体、同四聚体或二聚体的二聚体组成的稳定连接复合体的生产方法及用途
|
|
PL1874821T3
(pl)
|
2005-04-26 |
2013-09-30 |
Trion Pharma Gmbh |
Kombinacja przeciwciał i glikokortykoidów do leczenia raka
|
|
EP1913160A2
(en)
|
2005-07-29 |
2008-04-23 |
Bayer Healthcare LLC |
Diagnostic methods for the prediction of therapeutic success, recurrence free and overall survival in cancer therapy
|
|
WO2007031875A2
(en)
|
2005-08-26 |
2007-03-22 |
Glycart Biotechnology Ag |
Modified antigen binding molecules with altered cell signaling activity
|
|
CA2624086A1
(en)
|
2005-09-28 |
2007-04-05 |
H. Lee Moffitt Cancer Center |
Individualized cancer treatments
|
|
US20090252681A1
(en)
|
2005-10-11 |
2009-10-08 |
Ablynx N.V. |
Nanobodies and Polypeptides Against EGFR and IGF-IR
|
|
US20110052570A1
(en)
|
2005-10-26 |
2011-03-03 |
Children's Medical Center Corporation |
Method to prognose response to anti-egfr therapeutics
|
|
EP1792622A1
(en)
|
2005-11-11 |
2007-06-06 |
GPC Biotech AG |
Anti-proliferative combination therapy comprising a platinum-based chemotherapeutic agent and EGFR inhibitors or pyrimidine analogues
|
|
DK1963368T6
(da)
*
|
2005-12-13 |
2020-06-29 |
Lilly Co Eli |
Anti-il-17-antistoffer
|
|
EP1800695A1
(en)
|
2005-12-21 |
2007-06-27 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Immuno-RNA-constructs
|
|
AR056857A1
(es)
|
2005-12-30 |
2007-10-24 |
U3 Pharma Ag |
Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
|
|
US7498142B2
(en)
|
2006-01-31 |
2009-03-03 |
Yeda Research And Development Co., Ltd. |
Methods of identifying combinations of antibodies with an improved anti-tumor activity and compositions and methods using the antibodies
|
|
MX2008009970A
(es)
|
2006-02-01 |
2008-11-19 |
Univ Johns Hopkins |
Conjugados de polipeptido-acido nucleico para inmunoprofilaxis o inmunoterapia para desordenes neoplasicos o infecciosos.
|
|
US7951918B2
(en)
|
2006-03-17 |
2011-05-31 |
Biogen Idec Ma Inc. |
Stabilized polypeptide compositions
|
|
WO2007115571A2
(en)
|
2006-04-07 |
2007-10-18 |
Enkam Pharmaceuticals A/S |
Erbb receptor-derived peptide fragments
|
|
KR20090019890A
(ko)
|
2006-06-05 |
2009-02-25 |
제넨테크, 인크. |
Ｅｇｆ 또는 ｔｇｆ-알파 수준이 상승된 암 환자의 생존 연장
|
|
CN101627053A
(zh)
*
|
2006-06-12 |
2010-01-13 |
西福根有限公司 |
泛细胞表面受体特异的治疗剂
|
|
CN105837690A
(zh)
|
2006-06-12 |
2016-08-10 |
新兴产品开发西雅图有限公司 |
具有效应功能的单链多价结合蛋白
|
|
AR062223A1
(es)
|
2006-08-09 |
2008-10-22 |
Glycart Biotechnology Ag |
Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas
|
|
WO2008019394A2
(en)
|
2006-08-11 |
2008-02-14 |
The Government Of The United States Of America As Represented By The Secretary, Dept Of Health And Human Services |
Methods for treatment and diagnosis of psychiatric disorders
|
|
ES2399075T3
(es)
|
2006-08-30 |
2013-03-25 |
Genentech, Inc. |
Anticuerpos multiespecíficos
|
|
US8936780B2
(en)
|
2006-08-30 |
2015-01-20 |
Advanced Cardiovascular Systems, Inc. |
Stimuli responsive polyester amide particles
|
|
KR101106795B1
(ko)
|
2006-08-31 |
2012-01-18 |
에프. 호프만-라 로슈 아게 |
인슐린-유사 성장 인자-ｉ의 제조 방법
|
|
BRPI0717416A2
(pt)
|
2006-09-21 |
2013-11-12 |
Prometheus Lab Inc |
Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
|
|
WO2008036802A2
(en)
|
2006-09-21 |
2008-03-27 |
Prometheus Laboratories Inc. |
Antibody-based arrays for detecting multiple signal transducers in rare circulating cells
|
|
US20080076139A1
(en)
|
2006-09-21 |
2008-03-27 |
Sharat Singh |
Methods and compositions for detecting the activation states of multiple signal transducers in rare circulating cells
|
|
WO2011008990A1
(en)
|
2009-07-15 |
2011-01-20 |
Prometheus Laboratories Inc. |
Drug selection for gastric cancer therapy using antibody-based arrays
|
|
US20080112961A1
(en)
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
EP2092075A2
(en)
|
2006-11-06 |
2009-08-26 |
Source Precision Medicine, Inc. |
Gene expression profiling for identification, monitoring and treatment of melanoma
|
|
WO2008140493A2
(en)
|
2006-11-21 |
2008-11-20 |
The Regents Of The University Of Californina |
Anti-egfr family antibodies, bispecific anti-egfr family antibodies and methods of use thereof
|
|
EP2518508A1
(en)
|
2006-11-28 |
2012-10-31 |
U3 Pharma GmbH |
Activated HER3 as a marker for predicting therapeutic efficacy
|
|
SG177225A1
(en)
|
2006-12-01 |
2012-01-30 |
Agency Science Tech & Res |
Cancer-related protein kinases
|
|
US8652466B2
(en)
|
2006-12-08 |
2014-02-18 |
Macrogenics, Inc. |
Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
|
|
US8163886B2
(en)
|
2006-12-21 |
2012-04-24 |
Emd Millipore Corporation |
Purification of proteins
|
|
US8362217B2
(en)
|
2006-12-21 |
2013-01-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
US8569464B2
(en)
|
2006-12-21 |
2013-10-29 |
Emd Millipore Corporation |
Purification of proteins
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
AU2007343610C1
(en)
|
2007-01-17 |
2013-11-07 |
Immunomedics, Inc. |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
|
|
HRP20131113T1
(hr)
|
2007-02-16 |
2014-01-17 |
Merrimack Pharmaceuticals, Inc. |
Protutijela protiv erbb3 i njihova uporaba
|
|
PE20090681A1
(es)
|
2007-03-02 |
2009-06-10 |
Genentech Inc |
Prediccion de respuesta a un inhibidor her
|
|
AR065803A1
(es)
|
2007-03-23 |
2009-07-01 |
Smithkline Beecham Corp |
Uso de un polipeptido de il- 18 humana y un anticuerpo anti- cd para preparar unmedicamento
|
|
CA2681790A1
(en)
|
2007-03-30 |
2008-10-09 |
F. Hoffmann-La Roche Ag |
Composition of labeled and non-labeled monoclonal antibodies
|
|
EP2851091B1
(en)
|
2007-04-13 |
2017-12-27 |
Dana-Farber Cancer Institute, Inc. |
Methods for treating cancer resistant to ERBB therapeutics
|
|
FR2915115B1
(fr)
|
2007-04-23 |
2010-09-10 |
Sames Technologies |
Organe de pulverisation,dispositif de projection comportant un tel organe,installation de projection et methode de nettoyage d'un tel organe
|
|
US20100240035A1
(en)
|
2007-06-01 |
2010-09-23 |
The Regents Of The University Of California |
Multigene prognostic assay for lung cancer
|
|
US8529901B2
(en)
|
2007-06-06 |
2013-09-10 |
Hoffmann-La Roche, Inc. |
Composition of a first non-labeled monoclonal antibody binding to a tumor antigen and a non-cross reactive second monoclonal antibody labeled with a NIR fluorescence label
|
|
US20100183504A1
(en)
|
2007-06-14 |
2010-07-22 |
Fanqing Frank Chen |
Multimodal imaging probes for in vivo targeted and non-targeted imaging and therapeutics
|
|
JP2010531666A
(ja)
|
2007-06-26 |
2010-09-30 |
ユニバーシティ オブ マイアミ |
抗体−エンドスタチン融合タンパク質及びそのバリアント
|
|
WO2009003082A2
(en)
|
2007-06-26 |
2008-12-31 |
Vanderbilt University |
Immunological compositions as cancer biomarkers and/or therapeutics
|
|
WO2009009523A2
(en)
|
2007-07-09 |
2009-01-15 |
Genentech, Inc. |
Prevention of disulfide bond reduction during recombinant production of polypeptides
|
|
BRPI0813583A2
(pt)
|
2007-07-13 |
2014-12-30 |
Prometheus Lab Inc |
Métodos para selecionar um medicamento anticâncer, para identificar a resposta de um tumor pulmonar, e para prognosticar a resposta de um paciente, e, arranjo
|
|
WO2009023266A1
(en)
|
2007-08-14 |
2009-02-19 |
Ludwig Institute For Cancer Research |
Generation of antibodies to cell-surface receptors and cancer-associated proteins including egfr family members
|
|
KR101661770B1
(ko)
|
2007-09-21 |
2016-10-04 |
더 리전트 오브 더 유니버시티 오브 캘리포니아 |
표적화된 인터페론이 강력한 아폽토시스 및 항-종양 활성을 발휘함
|
|
US20110091473A1
(en)
|
2007-10-22 |
2011-04-21 |
Genmab A/S |
Novel antibody therapies
|
|
US20120047586A9
(en)
|
2007-10-24 |
2012-02-23 |
Otsuka Chemical Co., Ltd |
Polypeptide having enhanced effector function
|
|
CN103399144B
(zh)
|
2008-02-25 |
2015-10-28 |
雀巢产品技术援助有限公司 |
用抗体阵列选择乳腺癌治疗药物
|
|
US20090226455A1
(en)
|
2008-03-06 |
2009-09-10 |
Genentech, Inc. |
Combination therapy with c-met and her antagonists
|
|
EP2106806A1
(en)
|
2008-03-31 |
2009-10-07 |
Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. |
Nanoparticles for targeted delivery of active agents to the lung
|
|
MX2010011145A
(es)
|
2008-04-11 |
2011-04-11 |
Merrimack Pharmaceuticals Inc |
Enlazadores de la albumina de suero humana y conjugados de la misma.
|
|
CN102076355B
(zh)
|
2008-04-29 |
2014-05-07 |
Abbvie公司 |
双重可变结构域免疫球蛋白及其用途
|
|
BRPI0911442A2
(pt)
|
2008-04-30 |
2019-03-12 |
Immunogen, Inc. |
conjugados potentes e ligantes hidrofílicos
|
|
WO2009134870A1
(en)
|
2008-04-30 |
2009-11-05 |
Immunogen, Inc. |
Potent cell-binding agent drug conjugates
|
|
UY31800A
(es)
|
2008-05-05 |
2009-11-10 |
Smithkline Beckman Corp |
Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb
|
|
NZ589880A
(en)
|
2008-06-16 |
2012-10-26 |
Immunogen Inc |
Use of synergistic anti-cancer compositions comprising lenalidomide, at least one corticosteroid and at least one immunoconjugate
|
|
EP2138511A1
(en)
|
2008-06-27 |
2009-12-30 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
HER3 as a determinant for the prognosis of melanoma
|
|
AU2009268585C1
(en)
|
2008-07-08 |
2014-10-02 |
Abbvie Inc. |
Prostaglandin E2 dual variable domain immunoglobulins and uses thereof
|
|
WO2010009794A1
(en)
|
2008-07-25 |
2010-01-28 |
Merck Patent Gmbh, |
Method of determination of receptor binding saturation effected by monoclonal antibodies
|
|
US8056451B2
(en)
|
2008-07-28 |
2011-11-15 |
Irwin Industrial Tool Company |
Locking pliers
|
|
US20100033482A1
(en)
|
2008-08-11 |
2010-02-11 |
Interactive Relighting of Dynamic Refractive Objects |
Interactive Relighting of Dynamic Refractive Objects
|
|
BRPI0917871A2
(pt)
|
2008-08-15 |
2017-06-20 |
Merrimack Pharmaceuticals Inc |
agente terapêutico anti-erbb3 para uso em terapia de um tumor, métodos para predizer responsividade de um tumor de um agente terapêutco anti-erbb3, para selecionar terapia anti-erbb3 para um paciente, para predizer a resposta de células ao tratamento com um agente terapêutico, para identificar um biomarcador, e para evitar administração de uma droga para câncer anti-erbb3, e, kit para predizer a resposta das células ao tratamento com um agente terapêutico
|
|
US8080415B2
(en)
|
2008-09-26 |
2011-12-20 |
Eureka Therapeutics, Inc. |
Modified host cells and uses thereof
|
|
AU2009308707A1
(en)
|
2008-10-31 |
2010-05-06 |
Biogen Idec Ma Inc. |
LIGHT targeting molecules and uses thereof
|
|
EP2361098B1
(en)
|
2008-10-31 |
2019-08-28 |
The General Hospital Corporation |
Compositions and methods for delivering a substance to a biological target
|
|
CN102282168A
(zh)
|
2008-11-18 |
2011-12-14 |
梅里麦克制药股份有限公司 |
人血清白蛋白接头以及其结合物
|
|
US20100169729A1
(en)
|
2008-12-30 |
2010-07-01 |
Datta Shamanna M |
Enabling an integrated memory controller to transparently work with defective memory devices
|
|
NZ628463A
(en)
|
2009-01-14 |
2015-12-24 |
Us Health |
Ratio based biomarkers and methods for use thereof
|
|
EP2387717B1
(en)
|
2009-01-15 |
2014-12-10 |
Laboratory Corporation of America Holdings |
Methods of determining patient response by measurement of her-2 expression
|
|
SG172983A1
(en)
|
2009-01-15 |
2011-08-29 |
Lab Corp America Holdings |
Methods of determining patient response by measurement of her-3
|
|
HRP20230487T1
(hr)
|
2009-02-13 |
2023-07-21 |
Immunomedics, Inc. |
Imunokonjugati s unutarstaničnom vezom koja se može rascijepiti
|
|
CN102326081B
(zh)
|
2009-02-24 |
2014-11-19 |
霍夫曼-拉罗奇有限公司 |
s-ErbB-3作为癌症标志物的应用
|
|
US20110313137A1
(en)
|
2009-02-25 |
2011-12-22 |
Dongxing Zha |
Her2 antibody compositions
|
|
CN102356092B
(zh)
|
2009-03-20 |
2014-11-05 |
霍夫曼-拉罗奇有限公司 |
双特异性抗-her抗体
|
|
US8362215B2
(en)
|
2009-04-29 |
2013-01-29 |
Trellis Bioscience, Llc |
Antibodies immunoreactive with heregulin-coupled HER3
|
|
SG10201507044PA
(en)
|
2009-05-29 |
2015-10-29 |
Hoffmann La Roche |
Modulators for her2 signaling in her2 expressing patients with gastric cancer
|
|
US20120213705A1
(en)
|
2009-06-22 |
2012-08-23 |
Medimmune, Llc |
ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION
|
|
KR101844859B1
(ko)
|
2009-08-06 |
2018-05-18 |
제넨테크, 인크. |
단백질 정제 시의 바이러스 제거의 개선방법
|
|
US20110039300A1
(en)
|
2009-08-10 |
2011-02-17 |
Robert Bayer |
Antibodies with enhanced adcc functions
|
|
EP2467164A2
(en)
|
2009-08-21 |
2012-06-27 |
Merrimack Pharmaceuticals, Inc. |
Antibodies against the ectodomain of erbb3 and uses thereof
|
|
EP2475390A4
(en)
|
2009-09-09 |
2014-01-01 |
Quintiles Transnat Corp |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF TYROSINE KINASE RECEPTOR MEDIATION DISEASES OR DISORDERS
|
|
KR101808602B1
(ko)
|
2009-10-07 |
2017-12-13 |
마크로제닉스, 인크. |
푸코실화 정도의 변경으로 인해 개선된 이펙터 기능을 나타내는 Ｆｃ 영역-함유 폴리펩티드, 그것의 사용 방법
|
|
EP2486052A4
(en)
|
2009-10-09 |
2013-05-01 |
Merck Sharp & Dohme |
GENERATION, LABELING AND USE OF ANTI-HER3 ANTIBODIES
|
|
CA2777242A1
(en)
|
2009-10-14 |
2011-04-21 |
Merrimack Pharmaceuticals, Inc. |
Bispecific binding agents targeting igf-1r and erbb3 signalling and uses thereof
|
|
NO2719708T3
(enExample)
|
2009-11-13 |
2018-03-24 |
|
|
|
CA2784211C
(en)
|
2010-02-18 |
2019-12-24 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
|
US20130225424A1
(en)
|
2010-03-03 |
2013-08-29 |
Targeted Molecular Diagnostics, Llc |
Methods for determining responsiveness to a drug based upon determination of ras mutation and/or ras amplification
|
|
JP2013522237A
(ja)
|
2010-03-11 |
2013-06-13 |
メリマック ファーマシューティカルズ インコーポレーティッド |
トリプルネガティブおよび基底様乳癌の治療におけるｅｒｂｂ３阻害剤の使用
|
|
WO2011136911A2
(en)
|
2010-04-09 |
2011-11-03 |
Aveo Pharmaceuticals, Inc. |
Anti-erbb3 antibodies
|
|
WO2011139629A2
(en)
|
2010-04-26 |
2011-11-10 |
Biogen Idec Ma Inc. |
Light targeting molecules and uses thereof
|
|
EP2569334A4
(en)
|
2010-05-13 |
2014-01-22 |
Fox Chase Cancer Ct |
RECOMBINANT-PRODUCED ANTIBODIES FOR THE TARGETING OF ERBB SIGNALING MOLECULES AND METHOD FOR THEIR USE FOR DISEASE DIAGNOSIS AND TREATMENT
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
SG185354A1
(en)
|
2010-05-20 |
2012-12-28 |
Ablynx Nv |
Biological materials related to her3
|
|
AU2012211258A1
(en)
|
2011-01-27 |
2013-03-21 |
Merrimack Pharmaceuticals, Inc. |
Treatment of advanced solid stage tumors using anti-ErbB3 antibodies
|
|
JP6161540B2
(ja)
|
2011-02-04 |
2017-07-12 |
ジェネンテック， インコーポレイテッド |
Ｆｃ変異体及びそれらの生産方法
|
|
WO2012106578A1
(en)
|
2011-02-04 |
2012-08-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
HIV NEUTRALIZING ANTIBODIES HAVING MUTATIONS IN CONSTANT DOMAIN (Fc)
|
|
WO2012109133A1
(en)
|
2011-02-07 |
2012-08-16 |
Research Development Foundation |
Engineered immunoglobulin fc polypeptides
|
|
AU2012226398B9
(en)
|
2011-03-06 |
2017-04-13 |
Merck Serono S.A. |
Low fucose cell lines and uses thereof
|
|
CA2830501C
(en)
|
2011-03-17 |
2023-10-17 |
Cernostics, Inc. |
Systems and compositions for diagnosing barrett's esophagus and methods of using the same
|