PT3468621T - O domínio central das anexinas e suas utilizações no fornecimento e vacinação de antigénios - Google Patents

O domínio central das anexinas e suas utilizações no fornecimento e vacinação de antigénios

Info

Publication number
PT3468621T
PT3468621T PT177301124T PT17730112T PT3468621T PT 3468621 T PT3468621 T PT 3468621T PT 177301124 T PT177301124 T PT 177301124T PT 17730112 T PT17730112 T PT 17730112T PT 3468621 T PT3468621 T PT 3468621T
Authority
PT
Portugal
Prior art keywords
annexins
vaccination
core domain
antigen delivery
antigen
Prior art date
Application number
PT177301124T
Other languages
English (en)
Original Assignee
Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts filed Critical Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts
Publication of PT3468621T publication Critical patent/PT3468621T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
PT177301124T 2016-06-10 2017-06-08 O domínio central das anexinas e suas utilizações no fornecimento e vacinação de antigénios PT3468621T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16173925 2016-06-10

Publications (1)

Publication Number Publication Date
PT3468621T true PT3468621T (pt) 2022-12-21

Family

ID=56148135

Family Applications (1)

Application Number Title Priority Date Filing Date
PT177301124T PT3468621T (pt) 2016-06-10 2017-06-08 O domínio central das anexinas e suas utilizações no fornecimento e vacinação de antigénios

Country Status (15)

Country Link
US (2) US10947283B2 (pt)
EP (1) EP3468621B1 (pt)
JP (1) JP7377604B2 (pt)
CN (1) CN109328077A (pt)
CA (1) CA3027011A1 (pt)
DK (1) DK3468621T3 (pt)
ES (1) ES2933825T3 (pt)
FI (1) FI3468621T3 (pt)
HR (1) HRP20221372T1 (pt)
HU (1) HUE060537T2 (pt)
LT (1) LT3468621T (pt)
PL (1) PL3468621T3 (pt)
PT (1) PT3468621T (pt)
SI (1) SI3468621T1 (pt)
WO (1) WO2017211964A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3692984A1 (en) 2019-02-08 2020-08-12 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Annexin-coated particles

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001010199A1 (en) 1999-08-05 2001-02-15 Henry M. Jackson Foundation For The Advancement Of Military Medicine A knockout mouse for the tumor suppressor gene anx7
WO2001047510A2 (en) 1999-12-29 2001-07-05 Glaxo Group Limited Methods and compositions related to modulators of annexin and cartilage homeostasis
DE60124927T2 (de) 2000-09-01 2007-09-20 Philadelphia Health And Education Corp. Verfahren und zusammensetzungen zur inhibition der angiogenese
WO2005027965A1 (en) 2003-09-24 2005-03-31 Peter Krammer Antibodies against annexins, use thereof for therapy and diagnosis. use of annexins for therapy and diagnosis.
WO2006130525A2 (en) 2005-05-31 2006-12-07 Sidney Kimmel Cancer Center Methods for immunotherapy of cancer
NZ600143A (en) 2007-02-23 2013-01-25 Baylor Res Inst Therapeutic applications of activation of human antigen-presenting cells through dectin-1
WO2009049892A1 (en) 2007-10-17 2009-04-23 European Molecular Biology Laboratory (Embl) Polypeptides comprising an annexin core domain, compositions, methods and use thereof
WO2010002895A2 (en) * 2008-06-30 2010-01-07 The Regents Of The University Of Michigan Lysosomal phospholipase a2 (lpla2) activity as a diagnostic and therapeutic target for identifying and treating systemic lupus erythematosis
EP2515944B1 (en) * 2009-12-23 2020-04-22 Sanford-Burnham Medical Research Institute Methods and compositions related to annexin 1-binding compounds
TW201302793A (zh) * 2010-09-03 2013-01-16 Glaxo Group Ltd 新穎之抗原結合蛋白
WO2012048190A1 (en) * 2010-10-08 2012-04-12 Regents Of The University Of Minnesota Annexin ii compositions and methods
JP2014095643A (ja) 2012-11-11 2014-05-22 Nagoya City Univ 炎症性疾患治療薬のスクリーニング方法、並びに炎症性疾患の治療及び検査
JPWO2014126127A1 (ja) 2013-02-13 2017-02-02 国立大学法人北海道大学 ネクロプトーシス関連疾患の治療用医薬組成物及びその有効成分のスクリーニング方法
PL3068428T3 (pl) * 2013-11-13 2023-03-13 Regents Of The University Of Minnesota Sposoby i kompozycje wariantów aneksyny ii
EP3045470A1 (en) * 2015-01-15 2016-07-20 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Modulators of the function of the core domain of annexins, and uses thereof in autoimmune and/or cancer therapy

Also Published As

Publication number Publication date
JP7377604B2 (ja) 2023-11-10
PL3468621T3 (pl) 2023-01-30
US10947283B2 (en) 2021-03-16
HUE060537T2 (hu) 2023-03-28
JP2019517271A (ja) 2019-06-24
CN109328077A (zh) 2019-02-12
US11851463B2 (en) 2023-12-26
HRP20221372T1 (hr) 2023-01-06
FI3468621T3 (fi) 2023-01-13
US20190144513A1 (en) 2019-05-16
SI3468621T1 (sl) 2023-01-31
EP3468621A1 (en) 2019-04-17
EP3468621B1 (en) 2022-09-21
ES2933825T3 (es) 2023-02-14
US20210230238A1 (en) 2021-07-29
WO2017211964A1 (en) 2017-12-14
DK3468621T3 (da) 2022-12-05
LT3468621T (lt) 2022-12-27
CA3027011A1 (en) 2017-12-14

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