DK3468621T3 - Kernedomæne af annexiner og anvendelser deraf i antigenindgivelse og vaccination - Google Patents
Kernedomæne af annexiner og anvendelser deraf i antigenindgivelse og vaccination Download PDFInfo
- Publication number
- DK3468621T3 DK3468621T3 DK17730112.4T DK17730112T DK3468621T3 DK 3468621 T3 DK3468621 T3 DK 3468621T3 DK 17730112 T DK17730112 T DK 17730112T DK 3468621 T3 DK3468621 T3 DK 3468621T3
- Authority
- DK
- Denmark
- Prior art keywords
- annexins
- vaccination
- core domain
- antigen delivery
- antigen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16173925 | 2016-06-10 | ||
| PCT/EP2017/063985 WO2017211964A1 (en) | 2016-06-10 | 2017-06-08 | The core domain of annexins and uses thereof in antigen delivery and vaccination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3468621T3 true DK3468621T3 (da) | 2022-12-05 |
Family
ID=56148135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17730112.4T DK3468621T3 (da) | 2016-06-10 | 2017-06-08 | Kernedomæne af annexiner og anvendelser deraf i antigenindgivelse og vaccination |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US10947283B2 (da) |
| EP (1) | EP3468621B1 (da) |
| JP (1) | JP7377604B2 (da) |
| CN (1) | CN109328077A (da) |
| CA (1) | CA3027011A1 (da) |
| DK (1) | DK3468621T3 (da) |
| ES (1) | ES2933825T3 (da) |
| FI (1) | FI3468621T3 (da) |
| HR (1) | HRP20221372T1 (da) |
| HU (1) | HUE060537T2 (da) |
| LT (1) | LT3468621T (da) |
| PL (1) | PL3468621T3 (da) |
| PT (1) | PT3468621T (da) |
| SI (1) | SI3468621T1 (da) |
| WO (1) | WO2017211964A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3692984A1 (en) | 2019-02-08 | 2020-08-12 | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts | Annexin-coated particles |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003506056A (ja) | 1999-08-05 | 2003-02-18 | ヘンリー・エム・ジャクソン・ファンデイション・フォー・ジ・アドヴァンスメント・オヴ・ミリタリー・メディシン | 腫瘍抑制遺伝子ａｎｘ７のノックアウトマウス |
| ATE280580T1 (de) | 1999-12-29 | 2004-11-15 | Glaxo Group Ltd | Verwendung von annexin-modulatoren zur herstellung eines medikaments zur behandlung und/oder vorbeugung von arthritis und arthritischen erkrankungen |
| ES2272537T3 (es) | 2000-09-01 | 2007-05-01 | Philadelphia, Health And Education Corporation | Metodos y composiciones para inhibir la angiogenesis. |
| EP1670510A1 (en) | 2003-09-24 | 2006-06-21 | Peter Krammer | Antibodies against annexins, use thereof for therapy and diagnosis. use of annexins for therapy and diagnosis. |
| US20060286074A1 (en) * | 2005-05-31 | 2006-12-21 | Yucheng Tang | Methods for immunotherapy of cancer |
| BRPI0807617A2 (pt) | 2007-02-23 | 2014-07-22 | Baylor Res Inst | Aplicações terapêuticas de ativação de antígeno humano presente em células através de dectin-1. |
| WO2009049892A1 (en) | 2007-10-17 | 2009-04-23 | European Molecular Biology Laboratory (Embl) | Polypeptides comprising an annexin core domain, compositions, methods and use thereof |
| US8052970B2 (en) * | 2008-06-30 | 2011-11-08 | The Regents Of The University Of Michigan | Lysosomal phospholipase A2 (LPLA2) activity as a diagnostic and therapeutic target for identifying and treating systemic lupus erythematosis |
| EP2515944B1 (en) * | 2009-12-23 | 2020-04-22 | Sanford-Burnham Medical Research Institute | Methods and compositions related to annexin 1-binding compounds |
| TW201302793A (zh) * | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
| WO2012048190A1 (en) * | 2010-10-08 | 2012-04-12 | Regents Of The University Of Minnesota | Annexin ii compositions and methods |
| JP2014095643A (ja) | 2012-11-11 | 2014-05-22 | Nagoya City Univ | 炎症性疾患治療薬のスクリーニング方法、並びに炎症性疾患の治療及び検査 |
| WO2014126127A1 (ja) | 2013-02-13 | 2014-08-21 | 国立大学法人北海道大学 | ネクロプトーシス関連疾患の治療用医薬組成物及びその有効成分のスクリーニング方法 |
| CA2930567C (en) * | 2013-11-13 | 2023-09-26 | Regents Of The University Of Minnesota | Annexin ii variant compositions and methods |
| EP3045470A1 (en) * | 2015-01-15 | 2016-07-20 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Modulators of the function of the core domain of annexins, and uses thereof in autoimmune and/or cancer therapy |
-
2017
- 2017-06-08 PT PT177301124T patent/PT3468621T/pt unknown
- 2017-06-08 EP EP17730112.4A patent/EP3468621B1/en active Active
- 2017-06-08 LT LTEPPCT/EP2017/063985T patent/LT3468621T/lt unknown
- 2017-06-08 CA CA3027011A patent/CA3027011A1/en active Pending
- 2017-06-08 SI SI201731283T patent/SI3468621T1/sl unknown
- 2017-06-08 HR HRP20221372TT patent/HRP20221372T1/hr unknown
- 2017-06-08 ES ES17730112T patent/ES2933825T3/es active Active
- 2017-06-08 WO PCT/EP2017/063985 patent/WO2017211964A1/en unknown
- 2017-06-08 FI FIEP17730112.4T patent/FI3468621T3/fi active
- 2017-06-08 US US16/308,702 patent/US10947283B2/en active Active
- 2017-06-08 HU HUE17730112A patent/HUE060537T2/hu unknown
- 2017-06-08 CN CN201780035618.3A patent/CN109328077A/zh active Pending
- 2017-06-08 JP JP2018564358A patent/JP7377604B2/ja active Active
- 2017-06-08 PL PL17730112.4T patent/PL3468621T3/pl unknown
- 2017-06-08 DK DK17730112.4T patent/DK3468621T3/da active
-
2021
- 2021-01-21 US US17/154,477 patent/US11851463B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3027011A1 (en) | 2017-12-14 |
| FI3468621T3 (fi) | 2023-01-13 |
| HUE060537T2 (hu) | 2023-03-28 |
| LT3468621T (lt) | 2022-12-27 |
| WO2017211964A1 (en) | 2017-12-14 |
| JP7377604B2 (ja) | 2023-11-10 |
| US11851463B2 (en) | 2023-12-26 |
| JP2019517271A (ja) | 2019-06-24 |
| US10947283B2 (en) | 2021-03-16 |
| PT3468621T (pt) | 2022-12-21 |
| US20210230238A1 (en) | 2021-07-29 |
| CN109328077A (zh) | 2019-02-12 |
| HRP20221372T1 (hr) | 2023-01-06 |
| PL3468621T3 (pl) | 2023-01-30 |
| US20190144513A1 (en) | 2019-05-16 |
| SI3468621T1 (sl) | 2023-01-31 |
| EP3468621A1 (en) | 2019-04-17 |
| EP3468621B1 (en) | 2022-09-21 |
| ES2933825T3 (es) | 2023-02-14 |
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