JP2012529488A5 - - Google Patents
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- JP2012529488A5 JP2012529488A5 JP2012514554A JP2012514554A JP2012529488A5 JP 2012529488 A5 JP2012529488 A5 JP 2012529488A5 JP 2012514554 A JP2012514554 A JP 2012514554A JP 2012514554 A JP2012514554 A JP 2012514554A JP 2012529488 A5 JP2012529488 A5 JP 2012529488A5
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- Prior art keywords
- extract
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- 239000000284 extract Substances 0.000 claims 14
- 239000003814 drug Substances 0.000 claims 8
- 241000220259 Raphanus Species 0.000 claims 4
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 claims 4
- 230000035899 viability Effects 0.000 claims 3
- 206010061218 Inflammation Diseases 0.000 claims 2
- 206010052428 Wound Diseases 0.000 claims 2
- 208000027418 Wounds and injury Diseases 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 239000000469 ethanolic extract Substances 0.000 claims 2
- 208000030533 eye disease Diseases 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 239000000401 methanolic extract Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- 230000004083 survival effect Effects 0.000 claims 2
- 102100021569 Apoptosis regulator Bcl-2 Human genes 0.000 claims 1
- 101150017888 Bcl2 gene Proteins 0.000 claims 1
- 206010011985 Decubitus ulcer Diseases 0.000 claims 1
- 102000009024 Epidermal Growth Factor Human genes 0.000 claims 1
- 235000009709 Geum japonicum Nutrition 0.000 claims 1
- 241001618015 Geum japonicum Species 0.000 claims 1
- 208000004210 Pressure Ulcer Diseases 0.000 claims 1
- 101710098940 Pro-epidermal growth factor Proteins 0.000 claims 1
- 108010017842 Telomerase Proteins 0.000 claims 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 1
- 101150045355 akt1 gene Proteins 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
- 238000010255 intramuscular injection Methods 0.000 claims 1
- 239000007927 intramuscular injection Substances 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
- 230000029663 wound healing Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18670909P | 2009-06-12 | 2009-06-12 | |
| US61/186,709 | 2009-06-12 | ||
| US18790509P | 2009-06-17 | 2009-06-17 | |
| US61/187,905 | 2009-06-17 | ||
| PCT/IB2010/001426 WO2010143065A1 (en) | 2009-06-12 | 2010-06-11 | Compositions and methods for increasing lifespan and health span |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015126506A Division JP6187831B2 (ja) | 2009-06-12 | 2015-06-24 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012529488A JP2012529488A (ja) | 2012-11-22 |
| JP2012529488A5 true JP2012529488A5 (enExample) | 2013-07-25 |
| JP5892929B2 JP5892929B2 (ja) | 2016-03-23 |
Family
ID=43308481
Family Applications (11)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514549A Expired - Fee Related JP6076737B2 (ja) | 2009-06-12 | 2010-06-11 | 高血圧症の防止及び治療のための組成物並びに方法 |
| JP2012514548A Expired - Fee Related JP5689117B2 (ja) | 2009-06-12 | 2010-06-11 | 心不全を防止及び治療するための組成物及び方法 |
| JP2012514551A Expired - Fee Related JP5827618B2 (ja) | 2009-06-12 | 2010-06-11 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
| JP2012514550A Expired - Fee Related JP5892928B2 (ja) | 2009-06-12 | 2010-06-11 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
| JP2012514554A Expired - Fee Related JP5892929B2 (ja) | 2009-06-12 | 2010-06-11 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
| JP2012514552A Expired - Fee Related JP5712207B2 (ja) | 2009-06-12 | 2010-06-11 | 脳疾患及び状態の予防及び治療のための組成物及び方法 |
| JP2015111092A Pending JP2015155468A (ja) | 2009-06-12 | 2015-06-01 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
| JP2015124801A Pending JP2015164963A (ja) | 2009-06-12 | 2015-06-22 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
| JP2015126332A Pending JP2015164966A (ja) | 2009-06-12 | 2015-06-24 | 高血圧症の防止及び治療のための組成物並びに方法 |
| JP2015126506A Expired - Fee Related JP6187831B2 (ja) | 2009-06-12 | 2015-06-24 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
| JP2017090148A Withdrawn JP2017128608A (ja) | 2009-06-12 | 2017-04-28 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514549A Expired - Fee Related JP6076737B2 (ja) | 2009-06-12 | 2010-06-11 | 高血圧症の防止及び治療のための組成物並びに方法 |
| JP2012514548A Expired - Fee Related JP5689117B2 (ja) | 2009-06-12 | 2010-06-11 | 心不全を防止及び治療するための組成物及び方法 |
| JP2012514551A Expired - Fee Related JP5827618B2 (ja) | 2009-06-12 | 2010-06-11 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
| JP2012514550A Expired - Fee Related JP5892928B2 (ja) | 2009-06-12 | 2010-06-11 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
Family Applications After (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514552A Expired - Fee Related JP5712207B2 (ja) | 2009-06-12 | 2010-06-11 | 脳疾患及び状態の予防及び治療のための組成物及び方法 |
| JP2015111092A Pending JP2015155468A (ja) | 2009-06-12 | 2015-06-01 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
| JP2015124801A Pending JP2015164963A (ja) | 2009-06-12 | 2015-06-22 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
| JP2015126332A Pending JP2015164966A (ja) | 2009-06-12 | 2015-06-24 | 高血圧症の防止及び治療のための組成物並びに方法 |
| JP2015126506A Expired - Fee Related JP6187831B2 (ja) | 2009-06-12 | 2015-06-24 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
| JP2017090148A Withdrawn JP2017128608A (ja) | 2009-06-12 | 2017-04-28 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (7) | US9950019B2 (enExample) |
| EP (6) | EP2440209A4 (enExample) |
| JP (11) | JP6076737B2 (enExample) |
| CN (6) | CN102740870B (enExample) |
| AU (11) | AU2010258351B2 (enExample) |
| WO (6) | WO2010143059A1 (enExample) |
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| US12397008B2 (en) * | 2006-04-13 | 2025-08-26 | Lead Billion Limited | Pharmaceutical composition and method for regenerating myofibers in the treatment of muscle injuries |
| US9950019B2 (en) | 2009-06-12 | 2018-04-24 | Generex Pharmaceuticals, Inc. | Compositions and methods for the prevention and treatment of brain diseases and conditions |
| EP2655390B1 (en) * | 2010-12-23 | 2019-03-27 | Huya Bioscience International LLC | Purified cardiogenin isomer and related methods |
| JP6000521B2 (ja) * | 2011-08-10 | 2016-09-28 | 株式会社ブルボン | 血圧上昇抑制剤 |
| US10047034B2 (en) * | 2012-05-16 | 2018-08-14 | Prairie Berry Europe Gmbh | Polyhydroxylated pentacyclic triterpene acids as HMG-COA reductase inhibitors |
| US20140044813A1 (en) * | 2012-08-09 | 2014-02-13 | Kemin Industries, Inc. | Plant Extracts for Improving Cognitive Health and Function |
| CN103623753B (zh) * | 2013-11-27 | 2016-03-23 | 大兴安岭嘉迪欧营养原料有限公司 | 大兴安岭野生金老梅总三萜提取物的制备方法 |
| CN103623082B (zh) * | 2013-11-29 | 2016-08-17 | 江西中医药大学 | 覆盆子提取物及其应用 |
| US20150174057A1 (en) * | 2013-12-24 | 2015-06-25 | Generex Pharamaceutics Inc. | Compositions and methods for the prevention and treatment of oral diseases |
| JP2017507125A (ja) * | 2014-01-30 | 2017-03-16 | ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. | 認知機能を向上させるための植物抽出物 |
| CN105311030B (zh) * | 2014-06-06 | 2020-03-24 | 正大天晴药业集团股份有限公司 | 用于抗肿瘤的螺取代化合物 |
| CN104971091B (zh) * | 2015-06-03 | 2019-08-13 | 兴明生物医药技术(上海)有限公司 | 一种用于制备促进心肌再生药物的提取物的制备方法及其应用 |
| WO2017019182A1 (en) | 2015-07-24 | 2017-02-02 | Northeastern University | Quantitative magnetic resonance imaging of the vasculature |
| EP3340992B1 (en) * | 2015-09-04 | 2022-12-28 | The Board of Regents of the University of Texas System | Method for treatment of monocyte dysfunction and chronic inflammatory micro-and macro-vascular diseases |
| CN105106222B (zh) * | 2015-09-14 | 2020-05-08 | 新乡医学院 | 吐曼酸在制备治疗或预防雌激素缺乏引起的阿尔茨海默病药物中的应用 |
| CN106581006B (zh) * | 2015-10-16 | 2019-11-29 | 香港理工大学深圳研究院 | 三萜类化合物在制备治疗帕金森药物中的应用 |
| CN106153761B (zh) * | 2016-06-07 | 2018-08-14 | 贵州师范大学 | 同时检测无籽刺梨果实中3种黄酮类成分的方法 |
| US10856848B2 (en) | 2016-06-20 | 2020-12-08 | Butterfly Network, Inc. | Augmented reality interface for assisting a user to operate an ultrasound device |
| WO2018085330A1 (en) * | 2016-11-02 | 2018-05-11 | Temple University Of The Commonwealth System Of Higher Education | Systems and methods for reducing the viscosity of blood, suppressing turbulence in blood circulation, and curing rouleaux |
| IL270162B2 (en) * | 2017-04-25 | 2025-07-01 | Buck Inst Res Aging | ?-ketoglutarate (akg) and (i) a vitamin a compound, or (ii) a vitamin d compound, for use in delaying onset or delaying progression of frailty |
| CN106946971A (zh) * | 2017-04-28 | 2017-07-14 | 南宁馨艺荣生物科技有限公司 | 一种从积雪草中提取积雪草酸的工艺 |
| CN107445855B (zh) * | 2017-08-07 | 2018-12-14 | 绍兴市逸晨医疗科技有限公司 | 一种盐酸多西环素杂质c的制备方法 |
| WO2019172174A1 (ja) * | 2018-03-05 | 2019-09-12 | 日本新薬株式会社 | Rageシグナル阻害作用をもつ食品素材 |
| CN112567020A (zh) * | 2018-03-06 | 2021-03-26 | 埃皮博恩股份有限公司 | 可注射的即用的软骨、肌腱和韧带修复组合物及其使用方法 |
| WO2020023980A1 (en) * | 2018-07-27 | 2020-01-30 | Northeastern University | Diagnosis of dementia by vascular magnetic resonance imaging |
| KR102152182B1 (ko) * | 2018-09-05 | 2020-09-04 | 한국식품연구원 | 큰뱀무 추출물을 유효성분으로 함유하는 우울 증상 또는 스트레스의 개선, 예방 또는 치료용 조성물 |
| IL281761B2 (en) | 2018-09-25 | 2025-09-01 | Ponce De Leon Health Designated Activity Company | Process for preparing calcium alpha-ketoglutarate |
| CN113366032B (zh) | 2018-12-21 | 2024-01-23 | 阿朗新科新加坡私人有限公司 | 用于卤化不饱和异烯烃共聚物的湿法中的卤素回收 |
| CN109884222B (zh) * | 2019-01-17 | 2021-07-13 | 贵州中医药大学 | 一种小花清风藤的hplc指纹图谱建立方法 |
| KR102152174B1 (ko) * | 2020-03-30 | 2020-09-04 | 한국식품연구원 | 큰뱀무 추출물을 유효성분으로 함유하는 인지기능 장애의 개선, 예방 또는 치료용 조성물 |
| CN111643556A (zh) * | 2020-07-16 | 2020-09-11 | 杭州科倍安生物制药有限公司 | 一种用于预防和治疗痔疮的药物及其应用 |
| WO2022043407A1 (fr) | 2020-08-25 | 2022-03-03 | Laouarem Yousra | Compositions destinées au traitement des troubles neurologiques |
| KR102574207B1 (ko) * | 2020-12-03 | 2023-09-04 | 경북대학교 산학협력단 | 뱀무 추출물을 유효성분으로 하는 혈전성 질환 치료 또는 예방용 조성물 |
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| WO2008144706A2 (en) | 2007-05-21 | 2008-11-27 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Sweet gum fruit extract as a therapeutic agent |
| US20090022827A1 (en) | 2007-07-19 | 2009-01-22 | Ming Li | Agent and method for eliminating malignance of cancer cells without harmful effect to normal cells |
| CN101125171B (zh) | 2007-08-20 | 2010-05-26 | 刘凤元 | 一种男、女补强中药 |
| KR100891881B1 (ko) * | 2007-08-23 | 2009-04-07 | 대한민국 | 3,4,5-트리히드록시벤즈알데히드를 유효성분으로 포함하는고지혈증 및 mmp 과다활성으로 인한 혈관질환 예방 및치료용 조성물 |
| CN101406537B (zh) | 2007-10-11 | 2013-05-15 | 首都医科大学 | 柔毛水杨梅提取物用于制备治疗肥胖的药物的用途 |
| CN101274012B (zh) | 2008-01-23 | 2011-12-28 | 上海海天医药科技开发有限公司 | 夏枯草属植物提取物的组合物、制备方法及其药物用途 |
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