JP2012529486A5 - - Google Patents
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- JP2012529486A5 JP2012529486A5 JP2012514551A JP2012514551A JP2012529486A5 JP 2012529486 A5 JP2012529486 A5 JP 2012529486A5 JP 2012514551 A JP2012514551 A JP 2012514551A JP 2012514551 A JP2012514551 A JP 2012514551A JP 2012529486 A5 JP2012529486 A5 JP 2012529486A5
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- 150000001875 compounds Chemical class 0.000 claims 17
- 239000000203 mixture Substances 0.000 claims 17
- 150000003839 salts Chemical class 0.000 claims 10
- 239000011780 sodium chloride Substances 0.000 claims 10
- 239000012453 solvate Substances 0.000 claims 10
- 239000003814 drug Substances 0.000 claims 5
- 208000004981 Coronary Disease Diseases 0.000 claims 3
- 201000008739 coronary artery disease Diseases 0.000 claims 3
- 125000004438 haloalkoxy group Chemical group 0.000 claims 3
- 208000003067 Myocardial Ischemia Diseases 0.000 claims 2
- 125000002252 acyl group Chemical group 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 125000003342 alkenyl group Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000002870 angiogenesis inducing agent Substances 0.000 claims 2
- 125000003710 aryl alkyl group Chemical group 0.000 claims 2
- 125000003118 aryl group Chemical group 0.000 claims 2
- 125000004181 carboxyalkyl group Chemical group 0.000 claims 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 239000000284 extract Substances 0.000 claims 2
- 229910052736 halogen Inorganic materials 0.000 claims 2
- 150000002367 halogens Chemical class 0.000 claims 2
- 125000004415 heterocyclylalkyl group Chemical group 0.000 claims 2
- -1 hydroxy, carboxy, nitro, amino Chemical group 0.000 claims 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 2
- 230000000302 ischemic Effects 0.000 claims 2
- 150000002825 nitriles Chemical class 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102100010813 EGF Human genes 0.000 claims 1
- 101700033006 EGF Proteins 0.000 claims 1
- 210000003414 Extremities Anatomy 0.000 claims 1
- 102100013180 KDR Human genes 0.000 claims 1
- 208000010125 Myocardial Infarction Diseases 0.000 claims 1
- 210000004165 Myocardium Anatomy 0.000 claims 1
- 108091007928 VEGF receptors Proteins 0.000 claims 1
- 108010073929 Vascular Endothelial Growth Factor A Proteins 0.000 claims 1
- 102000009524 Vascular Endothelial Growth Factor A Human genes 0.000 claims 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 claims 1
- 125000002431 aminoalkoxy group Chemical group 0.000 claims 1
- 125000004103 aminoalkyl group Chemical group 0.000 claims 1
- 239000003416 antiarrhythmic agent Substances 0.000 claims 1
- 230000000747 cardiac effect Effects 0.000 claims 1
- 230000000271 cardiovascular Effects 0.000 claims 1
- 101710014509 celF Proteins 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 125000001188 haloalkyl group Chemical group 0.000 claims 1
- 125000001072 heteroaryl group Chemical group 0.000 claims 1
- 125000005114 heteroarylalkoxy group Chemical group 0.000 claims 1
- 125000005553 heteroaryloxy group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 125000005844 heterocyclyloxy group Chemical group 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 230000001338 necrotic Effects 0.000 claims 1
- 239000000546 pharmaceutic aid Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000001737 promoting Effects 0.000 claims 1
- 230000000250 revascularization Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000001519 tissues Anatomy 0.000 claims 1
- 0 Cc(c(C=*)c1N)c(C(C2)C2*C(C(C(*N)NC2(N=C)P3C(c4c5N)=*3)N)C2OCCc4c-2c(*)c5N)c-2c1N Chemical compound Cc(c(C=*)c1N)c(C(C2)C2*C(C(C(*N)NC2(N=C)P3C(c4c5N)=*3)N)C2OCCc4c-2c(*)c5N)c-2c1N 0.000 description 2
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18670909P | 2009-06-12 | 2009-06-12 | |
US61/186,709 | 2009-06-12 | ||
US18790509P | 2009-06-17 | 2009-06-17 | |
US61/187,905 | 2009-06-17 | ||
PCT/IB2010/001416 WO2010143062A1 (en) | 2009-06-12 | 2010-06-11 | Compositions and methods for prevention and treatment of coronary heart diseases |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015124801A Division JP2015164963A (ja) | 2009-06-12 | 2015-06-22 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2012529486A JP2012529486A (ja) | 2012-11-22 |
JP2012529486A5 true JP2012529486A5 (US07585860-20090908-C00112.png) | 2013-07-25 |
JP5827618B2 JP5827618B2 (ja) | 2015-12-02 |
Family
ID=43308481
Family Applications (11)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012514551A Expired - Fee Related JP5827618B2 (ja) | 2009-06-12 | 2010-06-11 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
JP2012514549A Expired - Fee Related JP6076737B2 (ja) | 2009-06-12 | 2010-06-11 | 高血圧症の防止及び治療のための組成物並びに方法 |
JP2012514550A Expired - Fee Related JP5892928B2 (ja) | 2009-06-12 | 2010-06-11 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
JP2012514548A Expired - Fee Related JP5689117B2 (ja) | 2009-06-12 | 2010-06-11 | 心不全を防止及び治療するための組成物及び方法 |
JP2012514552A Expired - Fee Related JP5712207B2 (ja) | 2009-06-12 | 2010-06-11 | 脳疾患及び状態の予防及び治療のための組成物及び方法 |
JP2012514554A Expired - Fee Related JP5892929B2 (ja) | 2009-06-12 | 2010-06-11 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
JP2015111092A Pending JP2015155468A (ja) | 2009-06-12 | 2015-06-01 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
JP2015124801A Pending JP2015164963A (ja) | 2009-06-12 | 2015-06-22 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
JP2015126506A Expired - Fee Related JP6187831B2 (ja) | 2009-06-12 | 2015-06-24 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
JP2015126332A Pending JP2015164966A (ja) | 2009-06-12 | 2015-06-24 | 高血圧症の防止及び治療のための組成物並びに方法 |
JP2017090148A Withdrawn JP2017128608A (ja) | 2009-06-12 | 2017-04-28 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
Family Applications After (10)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012514549A Expired - Fee Related JP6076737B2 (ja) | 2009-06-12 | 2010-06-11 | 高血圧症の防止及び治療のための組成物並びに方法 |
JP2012514550A Expired - Fee Related JP5892928B2 (ja) | 2009-06-12 | 2010-06-11 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
JP2012514548A Expired - Fee Related JP5689117B2 (ja) | 2009-06-12 | 2010-06-11 | 心不全を防止及び治療するための組成物及び方法 |
JP2012514552A Expired - Fee Related JP5712207B2 (ja) | 2009-06-12 | 2010-06-11 | 脳疾患及び状態の予防及び治療のための組成物及び方法 |
JP2012514554A Expired - Fee Related JP5892929B2 (ja) | 2009-06-12 | 2010-06-11 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
JP2015111092A Pending JP2015155468A (ja) | 2009-06-12 | 2015-06-01 | 赤血球凝固の予防及び治療のための組成物並びに方法 |
JP2015124801A Pending JP2015164963A (ja) | 2009-06-12 | 2015-06-22 | 冠動脈性心疾患の予防及び治療のための組成物及び方法 |
JP2015126506A Expired - Fee Related JP6187831B2 (ja) | 2009-06-12 | 2015-06-24 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
JP2015126332A Pending JP2015164966A (ja) | 2009-06-12 | 2015-06-24 | 高血圧症の防止及び治療のための組成物並びに方法 |
JP2017090148A Withdrawn JP2017128608A (ja) | 2009-06-12 | 2017-04-28 | 生存期間及び健康寿命を増加させるための組成物及び方法 |
Country Status (6)
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WO2013171100A1 (en) | 2012-05-16 | 2013-11-21 | Joachim Hans | Polyhydroxylated pentacyclic triterpene acids as hmg-coa reductase inhibitors |
US20140044813A1 (en) * | 2012-08-09 | 2014-02-13 | Kemin Industries, Inc. | Plant Extracts for Improving Cognitive Health and Function |
CN103623753B (zh) * | 2013-11-27 | 2016-03-23 | 大兴安岭嘉迪欧营养原料有限公司 | 大兴安岭野生金老梅总三萜提取物的制备方法 |
CN106074560A (zh) * | 2013-11-29 | 2016-11-09 | 江西中医药大学 | 覆盆子提取物的应用 |
US20150174057A1 (en) * | 2013-12-24 | 2015-06-25 | Generex Pharamaceutics Inc. | Compositions and methods for the prevention and treatment of oral diseases |
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CN105311030B (zh) * | 2014-06-06 | 2020-03-24 | 正大天晴药业集团股份有限公司 | 用于抗肿瘤的螺取代化合物 |
CN104971091B (zh) * | 2015-06-03 | 2019-08-13 | 兴明生物医药技术(上海)有限公司 | 一种用于制备促进心肌再生药物的提取物的制备方法及其应用 |
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CN106581006B (zh) * | 2015-10-16 | 2019-11-29 | 香港理工大学深圳研究院 | 三萜类化合物在制备治疗帕金森药物中的应用 |
CN106153761B (zh) * | 2016-06-07 | 2018-08-14 | 贵州师范大学 | 同时检测无籽刺梨果实中3种黄酮类成分的方法 |
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CN109562217A (zh) | 2016-11-02 | 2019-04-02 | 天普大学-联邦高等教育体系 | 用于降低血液粘稠度、抑制血液循环中的乱流及治愈缗线状形成的系统及方法 |
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CN106946971A (zh) * | 2017-04-28 | 2017-07-14 | 南宁馨艺荣生物科技有限公司 | 一种从积雪草中提取积雪草酸的工艺 |
CN107445855B (zh) * | 2017-08-07 | 2018-12-14 | 绍兴市逸晨医疗科技有限公司 | 一种盐酸多西环素杂质c的制备方法 |
JPWO2019172174A1 (ja) * | 2018-03-05 | 2021-02-12 | 日本新薬株式会社 | Rageシグナル阻害作用をもつ食品素材 |
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EP3829432A4 (en) * | 2018-07-27 | 2022-04-27 | Northeastern University | DIAGNOSIS OF DEMENTIA USING VASCULAR MAGNETIC RESONANCE IMAGING |
KR102152182B1 (ko) * | 2018-09-05 | 2020-09-04 | 한국식품연구원 | 큰뱀무 추출물을 유효성분으로 함유하는 우울 증상 또는 스트레스의 개선, 예방 또는 치료용 조성물 |
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