JP2010536767A5 - - Google Patents

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Publication number
JP2010536767A5
JP2010536767A5 JP2010521081A JP2010521081A JP2010536767A5 JP 2010536767 A5 JP2010536767 A5 JP 2010536767A5 JP 2010521081 A JP2010521081 A JP 2010521081A JP 2010521081 A JP2010521081 A JP 2010521081A JP 2010536767 A5 JP2010536767 A5 JP 2010536767A5
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Japan
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alkyl
cycloalkyl
ring
independently
haloalkyl
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JP2010521081A
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Japanese (ja)
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JP2010536767A (ja
JP5965102B2 (ja
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Priority claimed from PCT/US2008/072074 external-priority patent/WO2009025983A2/en
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Publication of JP2010536767A5 publication Critical patent/JP2010536767A5/ja
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JP2010521081A 2007-08-17 2008-08-04 ５−ハロアルキル−４，５−ジヒドロイソキサゾール誘導体を調製する方法 Active JP5965102B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US96511507P 2007-08-17 2007-08-17
US60/965,115 2007-08-17
US4345908P 2008-04-09 2008-04-09
US61/043,459 2008-04-09
US8045408P 2008-07-14 2008-07-14
US61/080,454 2008-07-14
PCT/US2008/072074 WO2009025983A2 (en) 2007-08-17 2008-08-04 Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014125041A Division JP2014221775A (ja) 2007-08-17 2014-06-18 ５−ハロアルキル−４，５−ジヒドロイソキサゾール誘導体を調製する方法

Publications (3)

Publication Number Publication Date
JP2010536767A JP2010536767A (ja) 2010-12-02
JP2010536767A5 true JP2010536767A5 (OSRAM) 2011-09-15
JP5965102B2 JP5965102B2 (ja) 2016-08-03

Family

ID=40350174

Family Applications (2)

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JP2010521081A Active JP5965102B2 (ja) 2007-08-17 2008-08-04 ５−ハロアルキル−４，５−ジヒドロイソキサゾール誘導体を調製する方法
JP2014125041A Pending JP2014221775A (ja) 2007-08-17 2014-06-18 ５−ハロアルキル−４，５−ジヒドロイソキサゾール誘導体を調製する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014125041A Pending JP2014221775A (ja) 2007-08-17 2014-06-18 ５−ハロアルキル−４，５−ジヒドロイソキサゾール誘導体を調製する方法

Country Status (19)

Country Link
US (2) US8217180B2 (OSRAM)
EP (1) EP2176244B1 (OSRAM)
JP (2) JP5965102B2 (OSRAM)
KR (2) KR101597839B1 (OSRAM)
CN (2) CN105693646A (OSRAM)
AR (1) AR067948A1 (OSRAM)
AU (1) AU2008289321B2 (OSRAM)
BR (1) BRPI0814153B8 (OSRAM)
CA (1) CA2693067C (OSRAM)
CO (1) CO6260136A2 (OSRAM)
ES (1) ES2587386T3 (OSRAM)
IL (1) IL203174A (OSRAM)
MX (2) MX2010001773A (OSRAM)
MY (2) MY176115A (OSRAM)
PT (1) PT2176244T (OSRAM)
RU (1) RU2536039C2 (OSRAM)
TW (3) TWI600639B (OSRAM)
WO (1) WO2009025983A2 (OSRAM)
ZA (1) ZA201000214B (OSRAM)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1930136B (zh) 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
BRPI0809770B8 (pt) 2007-06-13 2022-12-06 Du Pont Composto e composição para controlar uma praga de invertebrados
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
DK2957284T3 (en) * 2007-06-27 2018-02-05 Du Pont PROCEDURE TO CHECK ANIMALS FOR ANIMALS
WO2009001942A1 (ja) 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. ３－ヒドロキシプロパン－１－オン化合物、２－プロペン－１－オン化合物およびイソキサゾリン化合物の製造方法
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
KR20100075996A (ko) * 2007-10-03 2010-07-05 이 아이 듀폰 디 네모아 앤드 캄파니 무척추 해충의 방제를 위한 나프탈렌 이속사졸린 화합물
TWI583664B (zh) 2008-04-09 2017-05-21 杜邦股份有限公司 羰基化合物及其製備方法
KR101680912B1 (ko) 2008-07-09 2016-11-29 바스프 에스이 이속사졸린 화합물 ⅰ을 포함하는 살충 활성 혼합물
BRPI0915818A2 (pt) 2008-07-09 2015-08-04 Basf Se Mistura pesticida, composição pesticida, método para controlar fungos nocivos fitopatogênicos, para proteger plantas de fungos nocivos fitopatogênicos, para controlar insetos, aracnídeos ou nematódeos, para proteger plantas do ataque ou infestação por insetos, acarídeos ou nematódeos, e para a proteção de semente, semente, e, uso de uma mistura.
EP2331515B1 (en) 2008-08-22 2013-07-10 Syngenta Participations AG Insceticidal compounds
EP2331536B1 (en) 2008-08-22 2013-08-21 Syngenta Participations AG Insecticidal compounds
AU2009289711A1 (en) 2008-09-04 2010-03-11 Syngenta Limited Insecticidal compounds
CA2747986A1 (en) 2008-12-23 2010-07-01 Basf Se Substituted amidine compounds for combating animal pests
CN102325758A (zh) 2008-12-23 2012-01-18 巴斯夫欧洲公司 用于防治无脊椎动物害虫的亚胺化合物
JP2012522750A (ja) * 2009-04-01 2012-09-27 ビーエーエスエフ ソシエタス・ヨーロピア 無脊椎動物害虫を駆除するためのイソキサゾリン化合物
RS58691B1 (sr) 2009-12-17 2019-06-28 Merial Inc Antiparazitske kompozicije dihidroazola
CN102762543B (zh) 2010-02-01 2016-03-09 巴斯夫欧洲公司 用于防除动物害虫的取代的酮型异*唑啉化合物和衍生物
MX2012013758A (es) 2010-05-27 2013-01-24 Du Pont Forma cristalina de 4-[5-[3-cloro-5-trifluorometil)fenil]-4,5-dihi dro-5-(trifluorometil)-3-isoxazolil]-n-[2-oxo-2-[(2,2,2-trifluoro etil)amino]etil]-1-naftalenocarboxamida.
UY33403A (es) 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales
WO2012038851A1 (en) 2010-09-24 2012-03-29 Pfizer Inc. Isoxazoline oximes as antiparasitic agents
PT3150575T (pt) * 2010-09-27 2023-11-13 Corteva Agriscience Llc Método de preparação de 2-amino-n-(2,2,2- trifluoroetil)acetamida
AU2012215440B2 (en) 2011-02-10 2015-08-27 Novartis Tiergesundheit Ag Isoxazoline derivatives for controlling invertebrate pests
EP2683713B1 (en) 2011-03-10 2015-04-22 Novartis Tiergesundheit AG Isoxazole derivatives
JP6075563B2 (ja) 2011-11-08 2017-02-08 日産化学工業株式会社 光学活性イソキサゾリン化合物の触媒的不斉合成方法及び光学活性イソキサゾリン化合物
IN2014CN04376A (OSRAM) 2011-12-23 2015-09-04 Basf Se
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
SG11201603430XA (en) 2013-11-01 2016-05-30 Merial Ltd Antiparasitic and pesticidal isoxazoline compounds
US10045979B2 (en) 2014-05-19 2018-08-14 Merial Inc. Anthelmintic compounds
ES2887302T3 (es) 2014-10-31 2021-12-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden fipronil
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
PL3978483T3 (pl) 2016-04-06 2025-03-24 Boehringer Ingelheim Vetmedica Gmbh Krystaliczny solwat toluenowy (S)-afoksolaneru
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
KR102612648B1 (ko) * 2017-04-05 2023-12-11 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 (s)-아폭솔라너의 결정질 형태
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
JP7062792B2 (ja) 2018-02-13 2022-05-06 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
EP3781556B1 (en) 2018-04-19 2025-06-18 Gilead Sciences, Inc. Pd-1/pd-l1 inhibitors
EP3789382B1 (en) * 2018-04-27 2023-07-05 Kumiai Chemical Industry Co., Ltd. Production method for 5,5-di-substituted-4,5-dihydroisoxazole
CN118221646A (zh) 2018-07-13 2024-06-21 吉利德科学公司 Pd-1/pd-l1抑制剂
KR102635333B1 (ko) 2018-10-24 2024-02-15 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
WO2021072117A1 (en) 2019-10-08 2021-04-15 Donaldson Company, Inc. Filter media layers including mixed diameter fine fibers
BR112022024071A2 (pt) 2020-05-27 2022-12-20 Axial Therapeutics Inc Compostos moduladores de tlr2, composições farmacêuticas e usos dos mesmos
US11591544B2 (en) 2020-11-25 2023-02-28 Akagera Medicines, Inc. Ionizable cationic lipids
WO2023012821A1 (en) * 2021-08-01 2023-02-09 Zenfold Sustainable Technologies Private Limited A process for the preparation of carbamoyl benzamide phenyl isoxazoline class drug/s and its intermediates
CN115710185B (zh) * 2021-08-23 2024-05-03 中国石油化工股份有限公司 利用金属碳化物催化剂生产甲胺的方法
AU2023275780A1 (en) 2022-05-25 2024-12-05 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
CN116253658B (zh) * 2022-11-25 2023-08-11 济南久隆医药科技有限公司 一种阿福拉纳中间体合成方法
CN115772091B (zh) * 2023-01-05 2023-06-23 济南久隆医药科技有限公司 一种2-氨基-n-(2,2,2-三氟乙基)乙酰胺的合成方法
CN119899156A (zh) * 2023-10-27 2025-04-29 华北制药集团动物保健品有限责任公司 一种阿福拉纳的制备方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879532A (en) * 1974-01-18 1975-04-22 Shell Oil Co Control by isoxazoles of endoparasitic nematodes
US4129568A (en) * 1977-05-12 1978-12-12 Monsanto Company 2-[3-Aryl-2-isoxazolin-5-yl]benzoates
US5849736A (en) 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
WO1997041118A1 (en) 1996-04-26 1997-11-06 Nippon Soda Co., Ltd. Benzene derivatives substituted by heterocycles and herbicides
CA2206151A1 (en) 1996-06-06 1997-12-06 Rohm And Haas Company Benzyloxy substituted aromatics and their use as fungicides and insecticides
GB2351081A (en) 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
DE10114597A1 (de) * 2001-03-23 2002-10-02 Bayer Cropscience Gmbh Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
BR0313943A (pt) * 2002-08-26 2005-08-02 Nissan Chemical Ind Ltd Composto benzanilida substituìdo e agente de controle de organismo nocivo
DE10320782A1 (de) 2003-05-09 2004-11-25 Bayer Cropscience Ag Substituierte Oxyarene
JP2005272452A (ja) 2004-02-23 2005-10-06 Nissan Chem Ind Ltd 置換ベンズアニリド化合物及び有害生物防除剤
CN1930136B (zh) * 2004-03-05 2012-02-08 日产化学工业株式会社 异*唑啉取代苯甲酰胺化合物及有害生物防除剂
BRPI0507818A (pt) 2004-03-26 2007-07-10 Cytokine Pharmasciences Inc composto e métodos de inibição
JP5051340B2 (ja) * 2005-06-06 2012-10-17 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
MY146795A (en) 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
GB0514071D0 (en) 2005-07-07 2005-08-17 Zealand Pharma As N- or C- terminally modified small peptides
KR100546831B1 (ko) 2005-08-31 2006-01-25 (주) 마이크로프랜드 프로브 카드의 탐침팁 공정 방법
CA2621228C (en) * 2005-09-02 2014-05-27 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and pesticide
JP2007106756A (ja) 2005-09-14 2007-04-26 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
TWI266597B (en) * 2005-09-27 2006-11-11 Delta Electronics Inc Electronic apparatus capable of dissipating heat uniformly
US20090143410A1 (en) * 2005-12-14 2009-06-04 Kanu Maganbhai Patel Isoxazolines for Controlling Invertebrate Pests
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
CN101346336B (zh) 2005-12-26 2013-02-27 日产化学工业株式会社 1,3-二(取代苯基)-3-取代-2-丙烯-1-酮化合物和其盐
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
PL1997813T3 (pl) * 2006-03-10 2010-10-29 Nissan Chemical Ind Ltd Podstawiony związek izoksazolinowy i środek zwalczający szkodniki
WO2007123855A2 (en) 2006-04-20 2007-11-01 E. I. Du Pont De Nemours And Company Pyrazolines for controlling invertebrate pests
WO2007125984A1 (ja) 2006-04-28 2007-11-08 Nihon Nohyaku Co., Ltd. イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
EP2151437A4 (en) 2007-03-07 2012-05-02 Nissan Chemical Ind Ltd ISOXAZOLINE SUBSTITUTED BENZAMIDE COMPOUND AND PEST CONTROL AGENT
RU2009141185A (ru) 2007-04-10 2011-05-20 Байер КропСайенс АГ (DE) Инсектицидные производные арилизоксазолина
BRPI0809770B8 (pt) * 2007-06-13 2022-12-06 Du Pont Composto e composição para controlar uma praga de invertebrados
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
WO2009001942A1 (ja) * 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. ３－ヒドロキシプロパン－１－オン化合物、２－プロペン－１－オン化合物およびイソキサゾリン化合物の製造方法
DK2957284T3 (en) * 2007-06-27 2018-02-05 Du Pont PROCEDURE TO CHECK ANIMALS FOR ANIMALS
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
CN101801940B (zh) 2007-09-10 2013-04-10 日产化学工业株式会社 取代异*唑啉化合物和有害生物防除剂
KR20100075996A (ko) 2007-10-03 2010-07-05 이 아이 듀폰 디 네모아 앤드 캄파니 무척추 해충의 방제를 위한 나프탈렌 이속사졸린 화합물

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