BRPI0814153B8 - Método para preparar derivados de 5-haloalquil-4,5-diidroisoxazol e compostos de partida úteis no método - Google Patents

Método para preparar derivados de 5-haloalquil-4,5-diidroisoxazol e compostos de partida úteis no método

Info

Publication number
BRPI0814153B8
BRPI0814153B8 BRPI0814153A BRPI0814153A BRPI0814153B8 BR PI0814153 B8 BRPI0814153 B8 BR PI0814153B8 BR PI0814153 A BRPI0814153 A BR PI0814153A BR PI0814153 A BRPI0814153 A BR PI0814153A BR PI0814153 B8 BRPI0814153 B8 BR PI0814153B8
Authority
BR
Brazil
Prior art keywords
preparing
haloalkyl
compounds useful
starting compounds
dihydroisoxazole derivatives
Prior art date
Application number
BRPI0814153A
Other languages
English (en)
Inventor
David Annis Gary
Todd Smith Brenton
Original Assignee
Du Pont
Corteva Agriscience Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Corteva Agriscience Llc filed Critical Du Pont
Publication of BRPI0814153A2 publication Critical patent/BRPI0814153A2/pt
Publication of BRPI0814153B1 publication Critical patent/BRPI0814153B1/pt
Publication of BRPI0814153B8 publication Critical patent/BRPI0814153B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/38—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

MÉTODO PARA PREPARAR DERIVADOS DE 5-HALOALQUIL-4,5- DIIDROISOXAZOL E COMPOSTOS DE PARTIDA ÚTEIS NO MÉTODO. A presente invenção está relacionada a um método para preparar um composto de fórmula: (1): em que R1 é CHX2, CX3, CX2CHX2 ou CX2CX3; cada X é independentemente Cl ou F; Z é fenila opcionalmente substituída; e Q é fenila ou 1-naftalenila, cada um opcionalmente substituído como definido na descrição; compreendendo colocar em contato um composto de fórmula: (2).
BRPI0814153A 2007-08-17 2008-08-04 Método para preparar derivados de 5-haloalquil-4,5-diidroisoxazol e compostos de partida úteis no método BRPI0814153B8 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US96511507P 2007-08-17 2007-08-17
US60/965,115 2007-08-17
US4345908P 2008-04-09 2008-04-09
US61/043,459 2008-04-09
US8045408P 2008-07-14 2008-07-14
US61/080,454 2008-07-14
PCT/US2008/072074 WO2009025983A2 (en) 2007-08-17 2008-08-04 Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives

Publications (3)

Publication Number Publication Date
BRPI0814153A2 BRPI0814153A2 (pt) 2015-01-06
BRPI0814153B1 BRPI0814153B1 (pt) 2018-08-21
BRPI0814153B8 true BRPI0814153B8 (pt) 2022-12-06

Family

ID=40350174

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0814153A BRPI0814153B8 (pt) 2007-08-17 2008-08-04 Método para preparar derivados de 5-haloalquil-4,5-diidroisoxazol e compostos de partida úteis no método

Country Status (20)

Country Link
US (2) US8217180B2 (pt)
EP (1) EP2176244B1 (pt)
JP (2) JP5965102B2 (pt)
KR (2) KR101597839B1 (pt)
CN (2) CN101855215A (pt)
AR (1) AR067948A1 (pt)
AU (1) AU2008289321B2 (pt)
BR (1) BRPI0814153B8 (pt)
CA (1) CA2693067C (pt)
CO (1) CO6260136A2 (pt)
ES (1) ES2587386T3 (pt)
HK (1) HK1143373A1 (pt)
IL (1) IL203174A (pt)
MX (2) MX337588B (pt)
MY (2) MY150980A (pt)
PT (1) PT2176244T (pt)
RU (1) RU2536039C2 (pt)
TW (3) TWI461411B (pt)
WO (1) WO2009025983A2 (pt)
ZA (1) ZA201000214B (pt)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2526614T3 (es) 2004-03-05 2015-01-13 Nissan Chemical Industries, Ltd. Compuesto de benzamida sustituida con isoxazolina y agente de control de organismos nocivos
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
ES2445651T3 (es) 2007-06-13 2014-03-04 E. I. Du Pont De Nemours And Company Insecticidas de isoxazolina
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
ES2666187T3 (es) 2007-06-27 2018-05-03 E. I. Du Pont De Nemours And Company Procedimiento de control de plagas en animales
WO2009001942A1 (ja) 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. ３－ヒドロキシプロパン－１－オン化合物、２－プロペン－１－オン化合物およびイソキサゾリン化合物の製造方法
TWI461411B (zh) * 2007-08-17 2014-11-21 Du Pont 製備５－鹵烷基－４，５－二氫異唑衍生物之方法
JP5676262B2 (ja) 2007-10-03 2015-02-25 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 有害無脊椎生物の防除用ナフタレンイソキサゾリン化合物
TW201444787A (zh) 2008-04-09 2014-12-01 Du Pont 製備３-三氟甲基查耳酮（ｃｈａｌｃｏｎｅ）之方法
CN102088857A (zh) 2008-07-09 2011-06-08 巴斯夫欧洲公司 包含异噁唑啉化合物的杀虫活性混合物ⅱ
EP2306837B2 (en) 2008-07-09 2023-10-25 Basf Se Pesticidal active mixtures comprising isoxazoline compounds i
EP2331536B1 (en) 2008-08-22 2013-08-21 Syngenta Participations AG Insecticidal compounds
NZ590755A (en) 2008-08-22 2012-11-30 Syngenta Participations Ag Insecticidal compounds
NZ590756A (en) 2008-09-04 2013-01-25 Syngenta Participations Ag Insecticidal compounds
KR20110098848A (ko) 2008-12-23 2011-09-01 바스프 에스이 무척추동물 해충을 퇴치하기 위한 이민 화합물
CN102325759A (zh) 2008-12-23 2012-01-18 巴斯夫欧洲公司 用于防治动物害虫的取代脒化合物
US20120030841A1 (en) * 2009-04-01 2012-02-02 Basf Se Isoxazoline compounds for combating invertebrate pests
AP3106A (en) 2009-12-17 2015-01-31 Merial Ltd Antiparisitic dihydroazole compounds and compositions comprising same
JP2013518084A (ja) 2010-02-01 2013-05-20 ビーエーエスエフ ソシエタス・ヨーロピア 有害動物を駆除するための置換されたケトン性イソオキサゾリン化合物および誘導体
MY156670A (en) 2010-05-27 2016-03-15 Du Pont Crystalline form of 4-[5-[3-chloro-5-(trifluoromethly)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl) amino]ethyl]-1-naphthalenecarboxamide
UY33403A (es) 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales
WO2012038851A1 (en) 2010-09-24 2012-03-29 Pfizer Inc. Isoxazoline oximes as antiparasitic agents
MY161570A (en) 2010-09-27 2017-04-28 Du Pont Method for preparing 2-amino-n-(2,2,2-trifluoroethyl)acetamide
US20130324538A1 (en) 2011-02-10 2013-12-05 Noëlle Gauvry Isoxazoline derivatives for controlling invertebrate pests
MX2013010297A (es) 2011-03-10 2013-10-17 Novartis Ag Derivados de isoxazol.
JP6075563B2 (ja) 2011-11-08 2017-02-08 日産化学工業株式会社 光学活性イソキサゾリン化合物の触媒的不斉合成方法及び光学活性イソキサゾリン化合物
AU2012356947A1 (en) 2011-12-23 2014-07-10 Basf Se Isothiazoline compounds for combating invertebrate pests
SG11201503959VA (en) 2012-11-20 2015-06-29 Merial Inc Anthelmintic compounds and compositions and method of using thereof
EA030935B1 (ru) 2013-11-01 2018-10-31 Мериал, Инк. Антипаразитарные и пестицидные изоксазолиновые соединения
WO2015179414A1 (en) 2014-05-19 2015-11-26 Merial, Inc. Anthelmintic compounds
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
LT3440062T (lt) 2016-04-06 2021-12-10 Boehringer Ingelheim Animal Health USA Inc. Enantiomeru praturtintų izoksazolino junginių - (s)-afoksolanerio kristalinio tolueno solvato gamybos būdas
WO2018071535A1 (en) 2016-10-14 2018-04-19 Merial, Inc. Pesticidal and parasiticidal vinyl isoxazoline compounds
JP7222909B2 (ja) * 2017-04-05 2023-02-15 ベーリンガー・インゲルハイム・アニマル・ヘルス・ユーエスエー・インコーポレイテッド （ｓ）－アフォキソラネルの結晶形
US11589586B2 (en) 2017-08-14 2023-02-28 Boehringer Ingelheim Animal Health USA Inc. Pesticidal and parasiticidal pyrazole-isoxazoline compounds
PL3752501T3 (pl) 2018-02-13 2023-08-21 Gilead Sciences, Inc. Inhibitory pd-1/pd-l1
JP7242702B2 (ja) 2018-04-19 2023-03-20 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
EP3789382B1 (en) * 2018-04-27 2023-07-05 Kumiai Chemical Industry Co., Ltd. Production method for 5,5-di-substituted-4,5-dihydroisoxazole
KR20230159715A (ko) 2018-07-13 2023-11-21 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
KR102635333B1 (ko) 2018-10-24 2024-02-15 길리애드 사이언시즈, 인코포레이티드 Pd-1/pd-l1 억제제
AU2021280287A1 (en) 2020-05-27 2023-01-05 Axial Therapeutics, Inc. TLR2 modulator compounds, pharmaceutical compositions and uses thereof
EP4251170A1 (en) 2020-11-25 2023-10-04 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids, and related methods of use
WO2023012821A1 (en) * 2021-08-01 2023-02-09 Zenfold Sustainable Technologies Private Limited A process for the preparation of carbamoyl benzamide phenyl isoxazoline class drug/s and its intermediates
CN115710185B (zh) * 2021-08-23 2024-05-03 中国石油化工股份有限公司 利用金属碳化物催化剂生产甲胺的方法
US12064479B2 (en) 2022-05-25 2024-08-20 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
CN116903488B (zh) * 2022-11-25 2023-12-15 济南久隆医药科技有限公司 一种阿福拉纳的合成方法
CN115772091B (zh) * 2023-01-05 2023-06-23 济南久隆医药科技有限公司 一种2-氨基-n-(2,2,2-三氟乙基)乙酰胺的合成方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879532A (en) * 1974-01-18 1975-04-22 Shell Oil Co Control by isoxazoles of endoparasitic nematodes
US4129568A (en) * 1977-05-12 1978-12-12 Monsanto Company 2-[3-Aryl-2-isoxazolin-5-yl]benzoates
US5849736A (en) 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
GB9505651D0 (en) 1995-03-21 1995-05-10 Agrevo Uk Ltd AgrEvo UK Limited
BR9708828A (pt) 1996-04-26 1999-08-03 Nippon Soda Co Composto e composição herbicida
AU726670B2 (en) 1996-06-06 2000-11-16 Dow Agrosciences Llc Benzyloxy substituted aromatics and their use as fungicides and insecticides
GB2351081A (en) 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
DE10114597A1 (de) * 2001-03-23 2002-10-02 Bayer Cropscience Gmbh Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel
WO2004018410A1 (ja) * 2002-08-26 2004-03-04 Nissan Chemical Industries, Ltd. 置換ベンズアニリド化合物及び有害生物防除剤
DE10320782A1 (de) 2003-05-09 2004-11-25 Bayer Cropscience Ag Substituierte Oxyarene
JP2005272452A (ja) 2004-02-23 2005-10-06 Nissan Chem Ind Ltd 置換ベンズアニリド化合物及び有害生物防除剤
ES2526614T3 (es) 2004-03-05 2015-01-13 Nissan Chemical Industries, Ltd. Compuesto de benzamida sustituida con isoxazolina y agente de control de organismos nocivos
AU2005228417A1 (en) 2004-03-26 2005-10-13 Cytokine Pharmasciences, Inc. Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor
JP5051340B2 (ja) * 2005-06-06 2012-10-17 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
MY146795A (en) 2005-06-09 2012-09-28 Novartis Ag Process for the synthesis of organic compounds
GB0514071D0 (en) 2005-07-07 2005-08-17 Zealand Pharma As N- or C- terminally modified small peptides
KR100546831B1 (ko) 2005-08-31 2006-01-25 (주) 마이크로프랜드 프로브 카드의 탐침팁 공정 방법
AU2006285613B2 (en) * 2005-09-02 2011-11-17 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and harmful organism-controlling agent
JP2007106756A (ja) 2005-09-14 2007-04-26 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
TWI266597B (en) * 2005-09-27 2006-11-11 Delta Electronics Inc Electronic apparatus capable of dissipating heat uniformly
BRPI0620668A2 (pt) * 2005-12-14 2011-11-22 Du Pont composto da fórmula 1, composição que compreende composto, composição de controle de pragas invertebradas, composição de pulverização, composição de isca, dispositivo de armadilha, métodos de controle de pragas invertebradas, método de controle de baratas, formigas ou cupins e método de proteção de sementes contra pragas invertebradas
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
JP5304981B2 (ja) 2005-12-26 2013-10-02 日産化学工業株式会社 １，３−ビス（置換フェニル）−３−ヒドロキシプロパン−１−オンおよび２−プロペン−１−オン化合物およびその塩
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
EP1997813B1 (en) * 2006-03-10 2010-05-05 Nissan Chemical Industries, Ltd. Substituted isoxazoline compound and pest control agent
BRPI0710403A2 (pt) 2006-04-20 2011-08-09 Du Pont composto composição, composição de controle, de pulverização, de isca, dispositivo de armadilha, métodos de controle, métodos de proteção, semente tratada, composição de proteção
JPWO2007125984A1 (ja) 2006-04-28 2009-09-10 日本農薬株式会社 イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法
JP2008044880A (ja) 2006-08-15 2008-02-28 Bayer Cropscience Ag 殺虫性イソオキサゾリン類
JP5206993B2 (ja) 2007-03-07 2013-06-12 日産化学工業株式会社 イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤
KR20090130064A (ko) 2007-04-10 2009-12-17 바이엘 크롭사이언스 아게 살충성 아릴 이속사졸린 유도체
ES2445651T3 (es) 2007-06-13 2014-03-04 E. I. Du Pont De Nemours And Company Insecticidas de isoxazolina
TWI430995B (zh) * 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
ES2666187T3 (es) 2007-06-27 2018-05-03 E. I. Du Pont De Nemours And Company Procedimiento de control de plagas en animales
WO2009001942A1 (ja) * 2007-06-27 2008-12-31 Nissan Chemical Industries, Ltd. ３－ヒドロキシプロパン－１－オン化合物、２－プロペン－１－オン化合物およびイソキサゾリン化合物の製造方法
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
TWI461411B (zh) 2007-08-17 2014-11-21 Du Pont 製備５－鹵烷基－４，５－二氫異唑衍生物之方法
CN101801940B (zh) 2007-09-10 2013-04-10 日产化学工业株式会社 取代异*唑啉化合物和有害生物防除剂
JP5676262B2 (ja) * 2007-10-03 2015-02-25 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニーＥ．Ｉ．Ｄｕ Ｐｏｎｔ Ｄｅ Ｎｅｍｏｕｒｓ Ａｎｄ Ｃｏｍｐａｎｙ 有害無脊椎生物の防除用ナフタレンイソキサゾリン化合物

Also Published As

Publication number Publication date
ZA201000214B (en) 2011-03-30
WO2009025983A3 (en) 2009-05-07
CN101855215A (zh) 2010-10-06
TWI649303B (zh) 2019-02-01
RU2010109881A (ru) 2011-09-27
PT2176244T (pt) 2016-07-27
KR20100044892A (ko) 2010-04-30
IL203174A (en) 2014-08-31
TWI461411B (zh) 2014-11-21
CN105693646A (zh) 2016-06-22
US8513431B2 (en) 2013-08-20
EP2176244A2 (en) 2010-04-21
MY176115A (en) 2020-07-24
JP2014221775A (ja) 2014-11-27
ES2587386T3 (es) 2016-10-24
US20130165663A9 (en) 2013-06-27
JP2010536767A (ja) 2010-12-02
KR20150082693A (ko) 2015-07-15
TW201718454A (zh) 2017-06-01
MX337588B (es) 2016-03-11
TW200914429A (en) 2009-04-01
TW201434808A (zh) 2014-09-16
BRPI0814153B1 (pt) 2018-08-21
AR067948A1 (es) 2009-10-28
HK1143373A1 (zh) 2010-12-31
JP5965102B2 (ja) 2016-08-03
CA2693067C (en) 2016-10-11
MX2010001773A (es) 2010-03-10
TWI600639B (zh) 2017-10-01
EP2176244B1 (en) 2016-06-01
MY150980A (en) 2014-03-31
WO2009025983A4 (en) 2009-06-25
BRPI0814153A2 (pt) 2015-01-06
CA2693067A1 (en) 2009-02-26
US20120277442A1 (en) 2012-11-01
RU2536039C2 (ru) 2014-12-20
KR101597839B1 (ko) 2016-02-25
AU2008289321A1 (en) 2009-02-26
US20100249424A1 (en) 2010-09-30
AU2008289321B2 (en) 2014-02-20
CO6260136A2 (es) 2011-03-22
WO2009025983A2 (en) 2009-02-26
US8217180B2 (en) 2012-07-10

Similar Documents

Publication Publication Date Title
BRPI0814153B8 (pt) Método para preparar derivados de 5-haloalquil-4,5-diidroisoxazol e compostos de partida úteis no método
BRPI0713190A2 (pt) método para a preparação de um composto
ECSP099818A (es) Procesos para la preparacion de pirazoles
BRPI0514125A (pt) piridinas condensadas como inibidores de cinase
NO20084783L (no) Syntese av acylaminoalkenylenamider nyttige som substans P antagonister
BRPI0520870B8 (pt) compostos intermediários para a preparação de alfa-mercaptoacetanilidas de s-triazolila
SMP201100019B (it) Composti organici
PE20151752A1 (es) Amidas heterociclicas como inhibidores de cinasas
UY29121A1 (es) Serinamidas sustituidas por heteroaroilo
BR112014003597A2 (pt) composto da fórmula i, processo de preparação de compostos da fórmula i, composto da fórmula xii, composto das fórmulas viii e xi, composição agroquímica, uso de compostos da fórmula i ou viii e semente revestida com pelo menos um composto da fórmula i ou viii
BR112015028597A2 (pt) n-(tetrazol-5-il)- e n-(5-triazol-il)arilcarboxamidas, composição, utilização de um composto e método para o controle da vegetação
NI201000107A (es) Derivados de tiazol utilizados como inhibidores de pi 3 - cinasa.
CR10356A (es) Derivados de 4-benzilphthalazinona 2-sustituidos como antagonistas de histamina h1 y h3
EA201071019A1 (ru) Кристаллические формы производных фениламинопиримидина
EA200802380A1 (ru) Совместные кристаллы пирролидинонов
GT200800251A (es) Nitrilos espirociclicos como inhibidores de proteasa
BRPI1014802B8 (pt) profármacos de triptolida.
BR112013028598A2 (pt) método para promover o crescimento de plantas
BR112012032251A2 (pt) processo para a preparação de derivados da 2, 2-difluoroetilamina pela alquilação com 2,2 difluoroetil-1-haloetanos
BR112013028486A2 (pt) método para promover crescimento de planta
EA200900090A1 (ru) Бензиламины, способ их получения и их применение в качестве противовоспалительных средств
BR112012030534A2 (pt) moduladores de receptores 5-ht e métodos de uso dos mesmos
CR11578A (es) Derivados de oxadiazol activos e 1-fosfato de esfingosina
BRPI0907052B8 (pt) processo para a preparação de compostos
BRPI0514020A (pt) oxindóis oxazolidinonas como agentes antibacterianos

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B25A Requested transfer of rights approved

Owner name: CORTEVA AGRISCIENCE LLC (US)