MX337588B - Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol . - Google Patents
Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol .Info
- Publication number
- MX337588B MX337588B MX2013011829A MX2013011829A MX337588B MX 337588 B MX337588 B MX 337588B MX 2013011829 A MX2013011829 A MX 2013011829A MX 2013011829 A MX2013011829 A MX 2013011829A MX 337588 B MX337588 B MX 337588B
- Authority
- MX
- Mexico
- Prior art keywords
- preparing
- haloalkyl
- dihydroisoxazole derivatives
- dihydroisoxazole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
- C07C65/38—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups having unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La presente invención se refiere a un método para preparar un compuesto de Fórmula (1) (Ver Formula) en donde R1 es CHX2, CX3, CX2CHX2 o CXCX3 cada X es, independientemente, Ci o F; Z es fenilo opcionalmente sustituido; y Q es fenilo o l-naftalenilo, cada uno de ellos opcionalmente sustituido tal como se definió en la descripción; que comprende el contacto de un compuesto de Fórmula (2).
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96511507P | 2007-08-17 | 2007-08-17 | |
US4345908P | 2008-04-09 | 2008-04-09 | |
US8045408P | 2008-07-14 | 2008-07-14 | |
PCT/US2008/072074 WO2009025983A2 (en) | 2007-08-17 | 2008-08-04 | Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
MX337588B true MX337588B (es) | 2016-03-11 |
Family
ID=40350174
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010001773A MX2010001773A (es) | 2007-08-17 | 2008-08-04 | Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol . |
MX2013011829A MX337588B (es) | 2007-08-17 | 2008-08-04 | Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol . |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010001773A MX2010001773A (es) | 2007-08-17 | 2008-08-04 | Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol . |
Country Status (20)
Country | Link |
---|---|
US (2) | US8217180B2 (es) |
EP (1) | EP2176244B1 (es) |
JP (2) | JP5965102B2 (es) |
KR (2) | KR20150082693A (es) |
CN (2) | CN105693646A (es) |
AR (1) | AR067948A1 (es) |
AU (1) | AU2008289321B2 (es) |
BR (1) | BRPI0814153B8 (es) |
CA (1) | CA2693067C (es) |
CO (1) | CO6260136A2 (es) |
ES (1) | ES2587386T3 (es) |
HK (1) | HK1143373A1 (es) |
IL (1) | IL203174A (es) |
MX (2) | MX2010001773A (es) |
MY (2) | MY176115A (es) |
PT (1) | PT2176244T (es) |
RU (1) | RU2536039C2 (es) |
TW (3) | TWI649303B (es) |
WO (1) | WO2009025983A2 (es) |
ZA (1) | ZA201000214B (es) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101197482B1 (ko) | 2004-03-05 | 2012-11-09 | 닛산 가가쿠 고교 가부시키 가이샤 | 이속사졸린 치환 벤즈아미드 화합물 및 유해생물 방제제 |
TW200803740A (en) | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
EP2155701B1 (en) * | 2007-06-13 | 2013-12-11 | E. I. Du Pont de Nemours and Company | Isoxazoline insecticides |
TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
KR101714291B1 (ko) | 2007-06-27 | 2017-03-08 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 동물 해충 방제 방법 |
US8952175B2 (en) | 2007-06-27 | 2015-02-10 | Nissan Chemical Industries, Ltd. | Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound and method for production of isoxazoline compound |
TWI649303B (zh) | 2007-08-17 | 2019-02-01 | 杜邦股份有限公司 | 製備4-乙醯基-n-〔2-側氧基-2-〔(2,2,2-三氟乙基)胺基〕乙基〕-1-萘甲醯胺之化合物及方法 |
EP2193124B1 (en) | 2007-10-03 | 2012-12-19 | E. I. du Pont de Nemours and Company | Naphthalene isoxazoline compounds for control of invertebrate pests |
TWI518076B (zh) | 2008-04-09 | 2016-01-21 | 杜邦股份有限公司 | 製備雜環化合物之方法 |
JP2011527307A (ja) | 2008-07-09 | 2011-10-27 | ビーエーエスエフ ソシエタス・ヨーロピア | イソオキサゾリン化合物iを含む殺有害生物活性混合物 |
US8597688B2 (en) | 2008-07-09 | 2013-12-03 | Basf Se | Pesticidal mixtures comprising isoxazoline compounds II |
AU2009284229A1 (en) | 2008-08-22 | 2010-02-25 | Syngenta Limited | Insceticidal compounds |
EP2331536B1 (en) | 2008-08-22 | 2013-08-21 | Syngenta Participations AG | Insecticidal compounds |
EP2331535B1 (en) | 2008-09-04 | 2015-07-22 | Syngenta Participations AG | Insecticidal compounds |
KR20110098848A (ko) | 2008-12-23 | 2011-09-01 | 바스프 에스이 | 무척추동물 해충을 퇴치하기 위한 이민 화합물 |
AU2009331664A1 (en) | 2008-12-23 | 2011-07-14 | Basf Se | Substituted amidine compounds for combating animal pests |
WO2010112545A1 (en) * | 2009-04-01 | 2010-10-07 | Basf Se | Isoxazoline compounds for combating invertebrate pests |
ME03475B (me) | 2009-12-17 | 2020-01-20 | Merial Inc | Antiparazitske kompozicije dihidroazola |
BR112012019103A2 (pt) | 2010-02-01 | 2015-10-20 | Basf Se | compostos de isoxazolina cetônica, composto cetônico, composição agrícola, composição veterinária, uso de um composto, método e material de propagação de planta |
DK2576523T3 (en) | 2010-05-27 | 2016-04-18 | Du Pont | A crystalline form of 4- [5- [3-chloro-5- (trifluoromethyl) phenyl] -4,5-dihydro-5- (trifluoromethyl) -3-isoxazolyl] -N- [2-oxo-2 - [( 2,2,2-trifluoroethyl) amino] ethyl] - 1-naphthalenecarboxamide |
UY33403A (es) | 2010-06-17 | 2011-12-30 | Novartis Ag | Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales |
AU2011306489B2 (en) | 2010-09-24 | 2015-11-05 | Zoetis Services Llc | Isoxazoline oximes as antiparasitic agents |
CA2812718C (en) | 2010-09-27 | 2018-11-27 | E. I. Du Pont De Nemours And Company | Method for preparing 2-amino-n-(2,2,2-trifluoroethyl)acetamide |
EP2673273A1 (en) | 2011-02-10 | 2013-12-18 | Novartis AG | Isoxazoline derivatives for controlling invertebrate pests |
AR085657A1 (es) | 2011-03-10 | 2013-10-16 | Novartis Ag | Compuestos de isoxazol |
JP6075563B2 (ja) | 2011-11-08 | 2017-02-08 | 日産化学工業株式会社 | 光学活性イソキサゾリン化合物の触媒的不斉合成方法及び光学活性イソキサゾリン化合物 |
WO2013092943A1 (en) | 2011-12-23 | 2013-06-27 | Basf Se | Isothiazoline compounds for combating invertebrate pests |
CA2891926A1 (en) | 2012-11-20 | 2014-05-30 | Merial, Inc. | Anthelmintic compounds and compositions and method of using thereof |
DK3063144T3 (da) | 2013-11-01 | 2021-10-25 | Boehringer Ingelheim Animal Health Usa Inc | Antiparasitære og pesticid-isoxazolinforbindelser |
AR100530A1 (es) | 2014-05-19 | 2016-10-12 | Merial Inc | Compuestos antihelmínticos |
US10864193B2 (en) | 2014-10-31 | 2020-12-15 | Boehringer Ingelheim Animal Health USA Inc. | Parasiticidal compositions comprising fipronil at high concentrations |
UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
EP3440062B1 (en) | 2016-04-06 | 2021-10-06 | Boehringer Ingelheim Animal Health USA Inc. | Process for the preparation of enantiomerically enriched isoxazoline compounds - crystalline toluene solvate of (s)-afoxolaner |
CN110381738B (zh) | 2016-10-14 | 2021-07-16 | 勃林格殷格翰动物保健美国公司 | 农药的和杀寄生物的乙烯基异噁唑啉化合物 |
UY37665A (es) * | 2017-04-05 | 2018-10-31 | Merial Inc | Formas cristalinas de (s)-afoxolaner |
JP2020530850A (ja) | 2017-08-14 | 2020-10-29 | ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド | 殺有害生物および殺寄生生物ピラゾール−イソキサゾリン化合物 |
CR20200347A (es) | 2018-02-13 | 2020-09-23 | Gilead Sciences Inc | Inhibidores pd-1/pd-l1 |
CA3093130C (en) | 2018-04-19 | 2023-10-17 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
TWI810284B (zh) * | 2018-04-27 | 2023-08-01 | 日商組合化學工業股份有限公司 | 5,5-二取代-4,5-二氫異唑的製造方法 |
AU2019301811B2 (en) | 2018-07-13 | 2022-05-26 | Gilead Sciences, Inc. | PD-1/PD-L1 inhibitors |
WO2020086556A1 (en) | 2018-10-24 | 2020-04-30 | Gilead Sciences, Inc. | Pd-1/pd-l1 inhibitors |
WO2021242923A1 (en) | 2020-05-27 | 2021-12-02 | Axial Therapeutics, Inc. | Tlr2 modulator compounds, pharmaceutical compositions and uses thereof |
CA3200234A1 (en) | 2020-11-25 | 2022-06-02 | Daryl C. Drummond | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
WO2023012821A1 (en) * | 2021-08-01 | 2023-02-09 | Zenfold Sustainable Technologies Private Limited | A process for the preparation of carbamoyl benzamide phenyl isoxazoline class drug/s and its intermediates |
CN115710185A (zh) * | 2021-08-23 | 2023-02-24 | 中国石油化工股份有限公司 | 利用金属碳化物催化剂生产甲胺的方法 |
CN116253658B (zh) * | 2022-11-25 | 2023-08-11 | 济南久隆医药科技有限公司 | 一种阿福拉纳中间体合成方法 |
CN115772091B (zh) * | 2023-01-05 | 2023-06-23 | 济南久隆医药科技有限公司 | 一种2-氨基-n-(2,2,2-三氟乙基)乙酰胺的合成方法 |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3879532A (en) * | 1974-01-18 | 1975-04-22 | Shell Oil Co | Control by isoxazoles of endoparasitic nematodes |
US4129568A (en) * | 1977-05-12 | 1978-12-12 | Monsanto Company | 2-[3-Aryl-2-isoxazolin-5-yl]benzoates |
US5849736A (en) | 1993-11-24 | 1998-12-15 | The Dupont Merck Pharmaceutical Company | Isoxazoline and isoxazole fibrinogen receptor antagonists |
GB9505651D0 (en) | 1995-03-21 | 1995-05-10 | Agrevo Uk Ltd | AgrEvo UK Limited |
AU1671097A (en) | 1996-04-26 | 1997-11-19 | Nippon Soda Co., Ltd. | Benzene derivatives substituted by heterocycles and herbicides |
AU726670B2 (en) | 1996-06-06 | 2000-11-16 | Dow Agrosciences Llc | Benzyloxy substituted aromatics and their use as fungicides and insecticides |
GB2351081A (en) | 1999-06-18 | 2000-12-20 | Lilly Forschung Gmbh | Pharmaceutically active imidazoline compounds and analogues thereof |
DE10114597A1 (de) | 2001-03-23 | 2002-10-02 | Bayer Cropscience Gmbh | Arylisoxazolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Schädlingsbekämpfungsmittel |
EP1538138A4 (en) | 2002-08-26 | 2007-07-25 | Nissan Chemical Ind Ltd | SUBSTITUTED BENZANILIDE COMPOUND AND PROTECTIVE AGENTS |
DE10320782A1 (de) | 2003-05-09 | 2004-11-25 | Bayer Cropscience Ag | Substituierte Oxyarene |
JP2005272452A (ja) | 2004-02-23 | 2005-10-06 | Nissan Chem Ind Ltd | 置換ベンズアニリド化合物及び有害生物防除剤 |
KR101197482B1 (ko) | 2004-03-05 | 2012-11-09 | 닛산 가가쿠 고교 가부시키 가이샤 | 이속사졸린 치환 벤즈아미드 화합물 및 유해생물 방제제 |
AU2005228417A1 (en) | 2004-03-26 | 2005-10-13 | Cytokine Pharmasciences, Inc. | Compouns, compositions, processes of making, and methods of use related to inhibiting macrophage migration inhibitory factor |
JP5051340B2 (ja) * | 2005-06-06 | 2012-10-17 | 日産化学工業株式会社 | 置換イソキサゾリン化合物及び有害生物防除剤 |
MY146795A (en) | 2005-06-09 | 2012-09-28 | Novartis Ag | Process for the synthesis of organic compounds |
GB0514071D0 (en) | 2005-07-07 | 2005-08-17 | Zealand Pharma As | N- or C- terminally modified small peptides |
KR100546831B1 (ko) | 2005-08-31 | 2006-01-25 | (주) 마이크로프랜드 | 프로브 카드의 탐침팁 공정 방법 |
AU2006285613B2 (en) * | 2005-09-02 | 2011-11-17 | Nissan Chemical Corporation | Isoxazoline-substituted benzamide compound and harmful organism-controlling agent |
JP2007106756A (ja) | 2005-09-14 | 2007-04-26 | Nissan Chem Ind Ltd | 置換イソキサゾリン化合物及び有害生物防除剤 |
TWI266597B (en) * | 2005-09-27 | 2006-11-11 | Delta Electronics Inc | Electronic apparatus capable of dissipating heat uniformly |
EP1965645A2 (en) * | 2005-12-14 | 2008-09-10 | E.I. Du Pont De Nemours And Company | Isoxazolines for controlling invertebrate pests |
TW200803740A (en) * | 2005-12-16 | 2008-01-16 | Du Pont | 5-aryl isoxazolines for controlling invertebrate pests |
CN101346336B (zh) | 2005-12-26 | 2013-02-27 | 日产化学工业株式会社 | 1,3-二(取代苯基)-3-取代-2-丙烯-1-酮化合物和其盐 |
TWI412322B (zh) | 2005-12-30 | 2013-10-21 | Du Pont | 控制無脊椎害蟲之異唑啉 |
PL1997813T3 (pl) * | 2006-03-10 | 2010-10-29 | Nissan Chemical Ind Ltd | Podstawiony związek izoksazolinowy i środek zwalczający szkodniki |
MX2008013307A (es) | 2006-04-20 | 2008-10-27 | Du Pont | Pirazolinas para controlar plagas de invertebrados. |
JPWO2007125984A1 (ja) | 2006-04-28 | 2009-09-10 | 日本農薬株式会社 | イソキサゾリン誘導体及び有害生物防除剤並びにその使用方法 |
JP2008044880A (ja) | 2006-08-15 | 2008-02-28 | Bayer Cropscience Ag | 殺虫性イソオキサゾリン類 |
JP5206993B2 (ja) | 2007-03-07 | 2013-06-12 | 日産化学工業株式会社 | イソキサゾリン置換ベンズアミド化合物及び有害生物防除剤 |
RU2009141185A (ru) | 2007-04-10 | 2011-05-20 | Байер КропСайенс АГ (DE) | Инсектицидные производные арилизоксазолина |
EP2155701B1 (en) * | 2007-06-13 | 2013-12-11 | E. I. Du Pont de Nemours and Company | Isoxazoline insecticides |
TWI430995B (zh) | 2007-06-26 | 2014-03-21 | Du Pont | 萘異唑啉無脊椎有害動物控制劑 |
US8952175B2 (en) * | 2007-06-27 | 2015-02-10 | Nissan Chemical Industries, Ltd. | Method for production of 3-hydroxypropan-1-one compound, method for production of 2-propen-1-one compound and method for production of isoxazoline compound |
KR101714291B1 (ko) * | 2007-06-27 | 2017-03-08 | 이 아이 듀폰 디 네모아 앤드 캄파니 | 동물 해충 방제 방법 |
TWI556741B (zh) | 2007-08-17 | 2016-11-11 | 英特威特國際股份有限公司 | 異唑啉組成物及其作為抗寄生蟲藥上的應用 |
TWI649303B (zh) * | 2007-08-17 | 2019-02-01 | 杜邦股份有限公司 | 製備4-乙醯基-n-〔2-側氧基-2-〔(2,2,2-三氟乙基)胺基〕乙基〕-1-萘甲醯胺之化合物及方法 |
WO2009035004A1 (ja) | 2007-09-10 | 2009-03-19 | Nissan Chemical Industries, Ltd. | 置換イソキサゾリン化合物および有害生物防除剤 |
EP2193124B1 (en) * | 2007-10-03 | 2012-12-19 | E. I. du Pont de Nemours and Company | Naphthalene isoxazoline compounds for control of invertebrate pests |
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