JP2010515698A5 - - Google Patents

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JP2010515698A5
JP2010515698A5 JP2009545143A JP2009545143A JP2010515698A5 JP 2010515698 A5 JP2010515698 A5 JP 2010515698A5 JP 2009545143 A JP2009545143 A JP 2009545143A JP 2009545143 A JP2009545143 A JP 2009545143A JP 2010515698 A5 JP2010515698 A5 JP 2010515698A5
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formula
compound
biphenyl
salt
nitrogen protecting
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JP5715339B2 (ja
JP2010515698A (ja
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Priority claimed from PCT/EP2008/000142 external-priority patent/WO2008083967A2/en
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JP2009545143A 2007-01-12 2008-01-10 5−ビフェニル−4−アミノ−2−メチルペンタン酸の製造方法 Active JP5715339B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07100451 2007-01-12
EP07100451.9 2007-01-12
PCT/EP2008/000142 WO2008083967A2 (en) 2007-01-12 2008-01-10 Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid

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JP2010515698A JP2010515698A (ja) 2010-05-13
JP2010515698A5 true JP2010515698A5 (enExample) 2011-03-03
JP5715339B2 JP5715339B2 (ja) 2015-05-07

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JP2009545143A Active JP5715339B2 (ja) 2007-01-12 2008-01-10 5−ビフェニル−4−アミノ−2−メチルペンタン酸の製造方法

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US (4) US8115016B2 (enExample)
EP (1) EP2121578B1 (enExample)
JP (1) JP5715339B2 (enExample)
KR (2) KR101560005B1 (enExample)
CN (1) CN101631765B (enExample)
AR (1) AR064842A1 (enExample)
AU (2) AU2008204546B2 (enExample)
BR (1) BRPI0806700A8 (enExample)
CA (1) CA2674291C (enExample)
CL (1) CL2008000077A1 (enExample)
CO (1) CO6251311A2 (enExample)
CY (1) CY1118225T1 (enExample)
DK (1) DK2121578T3 (enExample)
EC (1) ECSP099508A (enExample)
ES (1) ES2602566T3 (enExample)
GT (1) GT200900195A (enExample)
HR (1) HRP20161484T1 (enExample)
HU (1) HUE030695T2 (enExample)
IL (1) IL199492A (enExample)
JO (1) JO3142B1 (enExample)
LT (1) LT2121578T (enExample)
MA (1) MA31284B1 (enExample)
MX (1) MX2009007474A (enExample)
MY (2) MY153432A (enExample)
NZ (1) NZ577910A (enExample)
PE (2) PE20121615A1 (enExample)
PH (1) PH12012502091A1 (enExample)
PL (1) PL2121578T3 (enExample)
PT (1) PT2121578T (enExample)
RU (1) RU2530900C2 (enExample)
SG (1) SG185318A1 (enExample)
SI (1) SI2121578T1 (enExample)
TN (1) TN2009000296A1 (enExample)
TW (1) TWI413638B (enExample)
WO (1) WO2008083967A2 (enExample)
ZA (1) ZA200904311B (enExample)

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CN107074744B (zh) * 2014-12-03 2019-06-18 上海翰森生物医药科技有限公司 Nep抑制剂结晶型游离酸、钙盐多晶型及其制备方法和应用
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CN104926707B (zh) * 2015-05-12 2017-10-27 江苏福瑞生物医药有限公司 一种药物中间体的合成方法
CN104829514B (zh) * 2015-05-12 2017-10-03 江苏福瑞生物医药有限公司 一种药物中间体的合成方法
CN104860894B (zh) * 2015-06-10 2017-05-17 北京博全健医药科技有限公司 一种抗心衰药lcz696的制备方法
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CN105168205A (zh) * 2015-08-18 2015-12-23 泰力特医药(湖北)有限公司 一种血管紧张素ii受体和脑啡肽酶受体双重抑制剂lcz696的制备方法
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CN105130869B (zh) * 2015-09-07 2017-12-26 曾伟 一种Entresto中间体(S)‑5‑(联苯‑4‑羰基)吡咯烷‑2‑酮的合成方法
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CN106977415B (zh) * 2016-01-15 2021-03-26 广东东阳光药业有限公司 一种沙库必曲的中间体及其制备方法
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CN107602399B (zh) * 2016-07-11 2020-09-25 江西东邦药业有限公司 一种脑啡肽酶抑制剂中间体的制备方法
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CN110407733A (zh) * 2018-04-26 2019-11-05 鲁南制药集团股份有限公司 一种沙库巴曲杂质化合物
CN110551151A (zh) * 2018-05-30 2019-12-10 微宏动力系统(湖州)有限公司 一种磷酸酯或亚磷酸酯的制备方法、电解液及二次电池
CN108727213B (zh) * 2018-06-29 2021-06-08 中国科学院上海有机化学研究所 一种沙库必曲的制备方法
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CN110878039A (zh) * 2019-12-18 2020-03-13 株洲千金药业股份有限公司 一种沙库巴曲缬沙坦钠杂质的制备方法
JP7064527B2 (ja) * 2020-05-01 2022-05-10 ノバルティス アーゲー サクビトリルカルシウム塩
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CN116113398A (zh) 2020-07-13 2023-05-12 艾德凡斯化学公司 用于保健品的支链氨基酸表面活性剂
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CN115677521B (zh) * 2022-11-16 2024-02-02 迪嘉药业集团股份有限公司 一种高纯度沙库巴曲钙的制备方法
CN117447341B (zh) * 2023-09-06 2025-11-18 杭州国瑞生物科技有限公司 一种沙库巴曲缬沙坦钠中间体的精制方法
CN117756622B (zh) * 2023-12-21 2026-04-28 安徽皓元药业有限公司 一种沙库巴曲关键中间体的制备方法

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