JP2010512859A5 - - Google Patents

Info

Publication number

JP2010512859A5

JP2010512859A5 JP2009541680A JP2009541680A JP2010512859A5 JP 2010512859 A5 JP2010512859 A5 JP 2010512859A5 JP 2009541680 A JP2009541680 A JP 2009541680A JP 2009541680 A JP2009541680 A JP 2009541680A JP 2010512859 A5 JP2010512859 A5 JP 2010512859A5

Authority

JP

Japan

Prior art keywords

tissue augmentation

implant

polymer

agents

group

Prior art date

2007-12-21

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 239000007943 implant Substances 0.000 claims 14
• 210000001519 tissue Anatomy 0.000 claims 13
• 230000003416 augmentation Effects 0.000 claims 11
• 229920000642 polymer Polymers 0.000 claims 10
• 125000003396 thiol group Chemical group [H]S* 0.000 claims 10
• 239000003795 chemical substances by application Substances 0.000 claims 5
• 239000000546 pharmaceutical excipient Substances 0.000 claims 3
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
• 229920001661 Chitosan Polymers 0.000 claims 2
• XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 2
• 235000018417 cysteine Nutrition 0.000 claims 2
• 229920002674 hyaluronan Polymers 0.000 claims 2
• 229960003160 hyaluronic acid Drugs 0.000 claims 2
• 238000002360 preparation method Methods 0.000 claims 2
• 239000002904 solvent Substances 0.000 claims 2
• XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 1
• 206010046996 Varicose vein Diseases 0.000 claims 1
• 239000004480 active ingredient Substances 0.000 claims 1
• 239000000654 additive Substances 0.000 claims 1
• 239000003732 agents acting on the eye Substances 0.000 claims 1
• 230000000202 analgesic effect Effects 0.000 claims 1
• 230000000844 anti-bacterial effect Effects 0.000 claims 1
• 230000000843 anti-fungal effect Effects 0.000 claims 1
• 230000002924 anti-infective effect Effects 0.000 claims 1
• 239000002260 anti-inflammatory agent Substances 0.000 claims 1
• 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
• 230000003110 anti-inflammatory effect Effects 0.000 claims 1
• 230000003356 anti-rheumatic effect Effects 0.000 claims 1
• 230000002921 anti-spasmodic effect Effects 0.000 claims 1
• 230000000840 anti-viral effect Effects 0.000 claims 1
• 239000000043 antiallergic agent Substances 0.000 claims 1
• 239000000739 antihistaminic agent Substances 0.000 claims 1
• 229940125715 antihistaminic agent Drugs 0.000 claims 1
• 239000003435 antirheumatic agent Substances 0.000 claims 1
• 230000003190 augmentative effect Effects 0.000 claims 1
• 229920005601 base polymer Polymers 0.000 claims 1
• 239000011230 binding agent Substances 0.000 claims 1
• 230000003115 biocidal effect Effects 0.000 claims 1
• 239000000337 buffer salt Substances 0.000 claims 1
• 230000000973 chemotherapeutic effect Effects 0.000 claims 1
• 239000000812 cholinergic antagonist Substances 0.000 claims 1
• 239000011248 coating agent Substances 0.000 claims 1
• 238000000576 coating method Methods 0.000 claims 1
• 210000002808 connective tissue Anatomy 0.000 claims 1
• UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 claims 1
• 239000000824 cytostatic agent Substances 0.000 claims 1
• 239000002274 desiccant Substances 0.000 claims 1
• 239000007884 disintegrant Substances 0.000 claims 1
• 239000000945 filler Substances 0.000 claims 1
• 150000004676 glycans Chemical class 0.000 claims 1
• 208000014617 hemorrhoid Diseases 0.000 claims 1
• 239000003589 local anesthetic agent Substances 0.000 claims 1
• 229960005015 local anesthetics Drugs 0.000 claims 1
• 239000000314 lubricant Substances 0.000 claims 1
• 229960003151 mercaptamine Drugs 0.000 claims 1
• 210000003205 muscle Anatomy 0.000 claims 1
• 229940125702 ophthalmic agent Drugs 0.000 claims 1
• 229940124531 pharmaceutical excipient Drugs 0.000 claims 1
• 229920001282 polysaccharide Polymers 0.000 claims 1
• 239000005017 polysaccharide Substances 0.000 claims 1
• 239000003755 preservative agent Substances 0.000 claims 1
• -1 softener Substances 0.000 claims 1
• 239000003381 stabilizer Substances 0.000 claims 1
• 238000011282 treatment Methods 0.000 claims 1
• 208000027185 varicose disease Diseases 0.000 claims 1
• 239000011782 vitamin Substances 0.000 claims 1
• 229940088594 vitamin Drugs 0.000 claims 1
• 229930003231 vitamin Natural products 0.000 claims 1
• 235000013343 vitamin Nutrition 0.000 claims 1