HRP20221427T1 - Kompozicije i postupci za liječenje rana - Google Patents
Kompozicije i postupci za liječenje rana Download PDFInfo
- Publication number
- HRP20221427T1 HRP20221427T1 HRP20221427TT HRP20221427T HRP20221427T1 HR P20221427 T1 HRP20221427 T1 HR P20221427T1 HR P20221427T T HRP20221427T T HR P20221427TT HR P20221427 T HRP20221427 T HR P20221427T HR P20221427 T1 HRP20221427 T1 HR P20221427T1
- Authority
- HR
- Croatia
- Prior art keywords
- composition
- wound
- composition according
- xav939
- peg
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims 19
- 206010052428 Wound Diseases 0.000 title claims 5
- 208000027418 Wounds and injury Diseases 0.000 title claims 5
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- KLGQSVMIPOVQAX-UHFFFAOYSA-N XAV939 Chemical compound N=1C=2CCSCC=2C(O)=NC=1C1=CC=C(C(F)(F)F)C=C1 KLGQSVMIPOVQAX-UHFFFAOYSA-N 0.000 claims 4
- 125000005647 linker group Chemical group 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 3
- 229920002674 hyaluronan Polymers 0.000 claims 3
- 229960003160 hyaluronic acid Drugs 0.000 claims 3
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 2
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 2
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 206010072170 Skin wound Diseases 0.000 claims 1
- 208000002847 Surgical Wound Diseases 0.000 claims 1
- 125000002947 alkylene group Chemical group 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 229910021389 graphene Inorganic materials 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/28—Polysaccharides or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polymers & Plastics (AREA)
- Lubricants (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Claims (15)
1. Kompozicija, koja obuhvaća:
komponentu matrice koja sadrži konjugat (GO-HA) grafen oksida (GO) i hijaluronske kiseline (HA), pri čemu su GO i HA kovalentno vezani preko povezivača;
3,5,7,8-tetrahidro-2-[4-(trifluorometil)fenil]-4H-tiopirano[4,3-d]pirimidin-4-on (XAV939); i
vodu.
2. Kompozicija prema patentnom zahtjevu 1, koja dalje obuhvaća polietilen glikol (PEG), pri čemu je poželjno da PEG ima molekularnu težinu od oko 200 do oko 400 daltona, i pri čemu je poželjno da je PEG u količini od oko 0.1 tež% do oko 20 tež% ukupne kompozicije.
3. Kompozicija prema patentnom zahtjevu 1, pri čemu povezivač obuhvaća 2-25 ugljika.
4. Kompozicija prema patentnom zahtjevu 1, pri čemu povezivač obuhvaća jednu ili više -CH2CH2O- jedinica.
5. Kompozicija prema patentnom zahtjevu 1, koja dalje obuhvaća zgušnjivač.
6. Kompozicija prema patentnom zahtjevu 5, gdje zgušnjivač obuhvaća hidroksipropil celulozu (HPC).
7. Kompozicija prema patentnom zahtjevu 1, pri čemu povezivač obuhvaća -Rx-Rs-Ry-, pri čemu Rx i Ry je svaki nezavisno izabran iz grupe koja se sastoji od -CO-, -COO-, -NH-, -NH-NH-, -NH-NH-CO-, -CS-, -S-, i -O-, i pri čemu RS je nesupstituirana ili supstituirana linearna alkilenska grupa koja ima 2-20 ugljika okosnice.
8. Kompozicija prema patentnom zahtjevu 7, pri čemu Rx i Ry je svaki -NH-NH-CO-.
9. Kompozicija prema patentnom zahtjevu 1, pri čemu maseni odnos XAV939 i GO-HA je od oko 1:2 do oko 2:1.
10. Kompozicija prema patentnom zahtjevu 1, pri čemu XAV939 čini od oko 0.001 tež% do oko 5 tež% ukupne kompozicije, poželjno od oko 0.01 tež% do oko 2 tež% ukupne kompozicije.
11. Medicinski uređaj koji obuhvaća:
supstrat, koji je poželjno flaster, jastučić, šav, gaza, traka, ili zavoj; i
kompoziciju prema bilo kojem od patentnih zahtjeva 1-10 koja je nanijeta na supstrat.
12. Kompozicija prema bilo kojem od patentnih zahtjeva 1-10 za topikalnu primjenu u liječenju kožne rane kod ljudi.
13. Kompozicija za primjenu prema patentnom zahtjevu 12, pri čemu rana je kirurška rana.
14. Kompozicija za primjenu prema patentnom zahtjevu 12, pri čemu rana je opekotina.
15. Kompozicija za primjenu prema patentnom zahtjevu 12, pri čemu rana je kronična rana.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762569025P | 2017-10-06 | 2017-10-06 | |
| US201862684439P | 2018-06-13 | 2018-06-13 | |
| EP18864379.5A EP3691649B1 (en) | 2017-10-06 | 2018-10-06 | Compositions and methods for wound treatment |
| PCT/US2018/054776 WO2019071242A1 (en) | 2017-10-06 | 2018-10-06 | COMPOSITIONS AND METHODS OF TREATING WOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20221427T1 true HRP20221427T1 (hr) | 2023-01-06 |
Family
ID=65992398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20221427TT HRP20221427T1 (hr) | 2017-10-06 | 2018-10-06 | Kompozicije i postupci za liječenje rana |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11291730B2 (hr) |
| EP (1) | EP3691649B1 (hr) |
| CN (1) | CN111194216B (hr) |
| CA (1) | CA3092171A1 (hr) |
| DK (1) | DK3691649T3 (hr) |
| ES (1) | ES2930254T3 (hr) |
| FI (1) | FI3691649T3 (hr) |
| HR (1) | HRP20221427T1 (hr) |
| HU (1) | HUE060980T2 (hr) |
| LT (1) | LT3691649T (hr) |
| PL (1) | PL3691649T3 (hr) |
| PT (1) | PT3691649T (hr) |
| RS (1) | RS63754B1 (hr) |
| SI (1) | SI3691649T1 (hr) |
| WO (1) | WO2019071242A1 (hr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2019000254A1 (es) * | 2019-01-31 | 2019-08-30 | Aerogel en base a óxido de grafeno y quitosano con aplicación hemóstica | |
| CN111359003B (zh) * | 2020-03-30 | 2020-12-29 | 安庆市康明纳包装有限公司 | 一种骨科创口抗菌防护膜及其制备方法 |
| MX2024003105A (es) * | 2021-09-13 | 2024-05-24 | Eluciderm Inc | Composicion para usarse en un metodo para la regeneracion y el crecimiento del cartilago despues de la lesion. |
| WO2024086246A2 (en) | 2022-10-18 | 2024-04-25 | Eluciderm Inc. | 2-substituted 3,4 a, 5, 7, 8, 8 a-hexahydro-4h-thiop yrano [4,3- djpyrimidin-4-ones for wound treatment |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649075A (en) * | 1984-08-09 | 1987-03-10 | Leonora Jost | Transdermal and transmucosal vortexed foam devices and the method of making |
| US4568343A (en) * | 1984-10-09 | 1986-02-04 | Alza Corporation | Skin permeation enhancer compositions |
| US5340586A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Methods and formulations for use in treating oophorectomized women |
| GB0202874D0 (en) * | 2002-02-07 | 2002-03-27 | Novartis Ag | Organic compounds |
| US20040202665A1 (en) * | 2002-07-01 | 2004-10-14 | Janette Lazarovits | Compositions and methods for therapeutic treatment |
| US20060051384A1 (en) * | 2004-09-07 | 2006-03-09 | 3M Innovative Properties Company | Antiseptic compositions and methods of use |
| US7652043B2 (en) | 2004-09-29 | 2010-01-26 | The Johns Hopkins University | WNT pathway antagonists |
| GT200600396A (es) * | 2005-09-07 | 2007-04-23 | Dispositivos para la aplicacion de medicamentos transdermicos conteniendo o-desmetil venlafaxina (odv) o sus sales | |
| EA201000673A1 (ru) | 2007-11-05 | 2011-04-29 | Новартис Аг | СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ ИЗМЕРЕНИЯ АКТИВАЦИИ Wnt И ДЛЯ ЛЕЧЕНИЯ Wnt-ОПОСРЕДОВАННЫХ РАКОВЫХ ЗАБОЛЕВАНИЙ |
| US20120318262A1 (en) | 2011-03-21 | 2012-12-20 | Ethan Lee | Pyrvinium Wound Treatment Methods and Devices |
| CN102727901A (zh) * | 2012-07-12 | 2012-10-17 | 上海师范大学 | 一种氧化石墨烯/透明质酸纳米药物载体材料及其制备方法和应用 |
| CA2921491C (en) | 2012-08-23 | 2022-06-21 | Susan Marie Metcalfe | Neurotherapeutic nanoparticle compositions and devices |
| CN103030140B (zh) * | 2012-12-21 | 2014-07-30 | 郑州大学 | 透明质酸修饰的氧化石墨烯及其药物组合物的制备方法与应用 |
| CN103980505B (zh) * | 2014-05-27 | 2016-08-17 | 武汉大学 | 透明质酸/氧化石墨烯纳米复合水凝胶的制备方法及医药组合物 |
| US20170128271A1 (en) | 2014-06-13 | 2017-05-11 | Advanced First Aid Research Pte. Ltd. | Thermally conductive material-infused hydrogel bandages |
| CN105288695B (zh) * | 2015-11-17 | 2018-06-15 | 张建刚 | 含氧化石墨烯成分的创可贴及其制备方法 |
| CA3019548A1 (en) | 2016-03-30 | 2017-10-05 | Convatec Technologies Inc. | Modified wound dressings |
| CN106916313A (zh) * | 2017-03-22 | 2017-07-04 | 中国科学院宁波材料技术与工程研究所 | 透明质酸修饰的聚(n‑异丙基丙烯酰胺‑丙烯酸)水凝胶及应用 |
| CN106893012B (zh) * | 2017-04-17 | 2018-07-20 | 山东宜建新材料技术有限公司 | 一种纳米银改性石墨烯晶体复合材料及其制备方法 |
-
2018
- 2018-10-06 EP EP18864379.5A patent/EP3691649B1/en active Active
- 2018-10-06 LT LTEPPCT/US2018/054776T patent/LT3691649T/lt unknown
- 2018-10-06 SI SI201830789T patent/SI3691649T1/sl unknown
- 2018-10-06 ES ES18864379T patent/ES2930254T3/es active Active
- 2018-10-06 CN CN201880065132.9A patent/CN111194216B/zh active Active
- 2018-10-06 CA CA3092171A patent/CA3092171A1/en active Pending
- 2018-10-06 FI FIEP18864379.5T patent/FI3691649T3/fi active
- 2018-10-06 WO PCT/US2018/054776 patent/WO2019071242A1/en unknown
- 2018-10-06 RS RS20221076A patent/RS63754B1/sr unknown
- 2018-10-06 DK DK18864379.5T patent/DK3691649T3/da active
- 2018-10-06 US US16/153,753 patent/US11291730B2/en active Active
- 2018-10-06 HR HRP20221427TT patent/HRP20221427T1/hr unknown
- 2018-10-06 PL PL18864379.5T patent/PL3691649T3/pl unknown
- 2018-10-06 PT PT188643795T patent/PT3691649T/pt unknown
- 2018-10-06 HU HUE18864379A patent/HUE060980T2/hu unknown
-
2020
- 2020-09-17 US US17/024,592 patent/US11369685B2/en active Active
-
2022
- 2022-06-24 US US17/808,978 patent/US12059469B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20230000991A1 (en) | 2023-01-05 |
| PL3691649T3 (pl) | 2022-11-21 |
| US20190105398A1 (en) | 2019-04-11 |
| LT3691649T (lt) | 2023-01-10 |
| DK3691649T3 (da) | 2022-12-12 |
| US11291730B2 (en) | 2022-04-05 |
| FI3691649T3 (fi) | 2023-01-13 |
| EP3691649A1 (en) | 2020-08-12 |
| SI3691649T1 (sl) | 2023-04-28 |
| HUE060980T2 (hu) | 2023-05-28 |
| EP3691649B1 (en) | 2022-10-12 |
| ES2930254T3 (es) | 2022-12-09 |
| PT3691649T (pt) | 2022-11-11 |
| US12059469B2 (en) | 2024-08-13 |
| US11369685B2 (en) | 2022-06-28 |
| EP3691649A4 (en) | 2021-06-30 |
| US20210000959A1 (en) | 2021-01-07 |
| CN111194216B (zh) | 2024-02-13 |
| WO2019071242A1 (en) | 2019-04-11 |
| RS63754B1 (sr) | 2022-12-30 |
| CN111194216A (zh) | 2020-05-22 |
| CA3092171A1 (en) | 2019-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HRP20221427T1 (hr) | Kompozicije i postupci za liječenje rana | |
| Torkaman et al. | Modification of chitosan using amino acids for wound healing purposes: A review | |
| CY1123334T1 (el) | Σκευασματα φιναστεριδης για αποδεσμευση φαρμακου στα μαλλια και στο τριχωτο της κεφαλης | |
| JP2006513194A (ja) | 海藻抽出物およびグリセリンを含有する自己接着性ポリマーマトリックス | |
| Hao et al. | Injectable self-healing first-aid tissue adhesives with outstanding hemostatic and antibacterial performances for trauma emergency care | |
| HRP20191871T1 (hr) | Ionski vodeni pripravci | |
| JP6986581B2 (ja) | パップ剤 | |
| JP2010512859A5 (hr) | ||
| ES2755137T3 (es) | Apósito para heridas de pasta de quitosano | |
| JP2006501133A5 (hr) | ||
| ES2705028T3 (es) | Yeso a base de agua | |
| JP2017518101A5 (hr) | ||
| KR20100107419A (ko) | 화장품 팩용 겔 시트 | |
| JP2011522879A5 (hr) | ||
| Qureshi et al. | Chitosan and carrageenan‐based biocompatible hydrogel platforms for cosmeceutical, drug delivery, and biomedical applications | |
| ES2572758T3 (es) | Parche y preparación de parche | |
| HRP20200971T1 (hr) | Modulacija djelovanja epidermalnog faktora rasta koji veže heparin u svrhu zacijeljivanja membrane bubnjića | |
| RU2016117398A (ru) | Композиции полиинозиновой-полицитидиловой кислоты (поли (и:ц)) для лечения инфекций верхних дыхательных путей | |
| CN106459693A (zh) | 用于医学应用的改进的压敏粘合剂 | |
| JP2015504860A5 (hr) | ||
| Mayet et al. | Synthesis of a semi-interpenetrating polymer network as a bioactive curcumin film | |
| Lu et al. | Recent advances in adhesive materials used in the biomedical field: Adhesive properties, mechanism, and applications | |
| Zhu et al. | Naturally Derived Injectable Dual-Cross-Linked Adhesive Hydrogel for Acute Hemorrhage Control and Wound Healing | |
| Ding et al. | Multifunctional hydrogel bioscaffolds based on polysaccharide to promote wound healing: A review | |
| RU2011136311A (ru) | Фармацевтические композиции для обезвоживания, атрофии и удаления патологических тканей |