JP2011521969A5 - - Google Patents
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- Publication number
- JP2011521969A5 JP2011521969A5 JP2011511843A JP2011511843A JP2011521969A5 JP 2011521969 A5 JP2011521969 A5 JP 2011521969A5 JP 2011511843 A JP2011511843 A JP 2011511843A JP 2011511843 A JP2011511843 A JP 2011511843A JP 2011521969 A5 JP2011521969 A5 JP 2011521969A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- kinase
- inhibitor
- activin receptor
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5746108P | 2008-05-30 | 2008-05-30 | |
| US61/057,461 | 2008-05-30 | ||
| PCT/US2009/045607 WO2009146408A1 (en) | 2008-05-30 | 2009-05-29 | Methods for using tgf-b receptor inhibitors or activin-like kinase (alk) 5 inhibitors a-83-01 and sb-431542 to treat eye disease and wound healing conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011521969A JP2011521969A (ja) | 2011-07-28 |
| JP2011521969A5 true JP2011521969A5 (enExample) | 2011-09-08 |
Family
ID=41377599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011511843A Pending JP2011521969A (ja) | 2008-05-30 | 2009-05-29 | 眼疾患を治療するためのTGF−β受容体阻害剤又はアクチビン様キナーゼ(ALK)5阻害剤、A−83−01及びSB−431542の使用方法及び創傷治療条件 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100087486A1 (enExample) |
| EP (1) | EP2285380A4 (enExample) |
| JP (1) | JP2011521969A (enExample) |
| CN (1) | CN102083439A (enExample) |
| WO (1) | WO2009146408A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012524073A (ja) * | 2009-04-17 | 2012-10-11 | スムマ ヘルス システムズ エルエルシー | 眼球瘢痕化を抑制するための形質転換成長因子−β受容体阻害剤の使用 |
| BR112013003600A2 (pt) * | 2010-08-17 | 2016-08-16 | Allergan Inc | agonistas ep2 ou ep4 para o tratamento de névoa da córnea |
| US10195249B2 (en) | 2012-11-02 | 2019-02-05 | Celgene Corporation | Activin-ActRII antagonists and uses for treating bone and other disorders |
| CA2909230C (en) | 2013-04-12 | 2021-06-15 | Kyoto University | Method for inducing alveolar epithelial progenitor cells |
| JP6429280B2 (ja) | 2013-05-14 | 2018-11-28 | 国立大学法人京都大学 | 効率的な心筋細胞の誘導方法 |
| MX386503B (es) | 2013-07-30 | 2025-03-19 | Kyoto Prefectural Public Univ Corp | Medicamentos terapeuticos de matriz extracelular endotelial corneal. |
| WO2015020113A1 (ja) | 2013-08-07 | 2015-02-12 | 国立大学法人京都大学 | 膵ホルモン産生細胞の製造法 |
| CN105849255A (zh) | 2013-09-05 | 2016-08-10 | 国立大学法人京都大学 | 新的产多巴胺神经前体细胞诱导方法 |
| WO2015064768A1 (ja) | 2013-10-31 | 2015-05-07 | 京都府公立大学法人 | 角膜内皮の小胞体細胞死関連疾患治療薬 |
| CN106536718B (zh) | 2014-05-21 | 2021-04-27 | 国立大学法人京都大学 | 胰芽细胞的制造方法及含有胰芽细胞的胰疾病治疗剂 |
| CA3005975A1 (en) | 2015-11-23 | 2017-06-01 | Acceleron Pharma Inc. | Methods for treating eye disorders |
| WO2017183736A1 (ja) | 2016-04-22 | 2017-10-26 | 国立大学法人京都大学 | ドーパミン産生神経前駆細胞の製造方法 |
| CN106282092A (zh) * | 2016-09-07 | 2017-01-04 | 山东省眼科研究所 | 一种角膜内皮分离和扩增培养液 |
| EP3633026A4 (en) | 2017-05-25 | 2021-03-10 | Kyoto University | METHOD FOR INDUCING THE DIFFERENTIATION OF A MESODERMAL INTERMEDIATE CELL TO A KIDNEY PRECURSOR CELL AND METHOD FOR INDUCING THE DIFFERENTIATION OF A PLURIPOTENT STEM CELL FROM A KIDNEY PRECURSOR CELL |
| WO2019160148A1 (ja) | 2018-02-19 | 2019-08-22 | 大日本住友製薬株式会社 | 細胞凝集体、細胞凝集体の混合物及びそれらの製造方法 |
| JP7357369B2 (ja) | 2018-07-23 | 2023-10-06 | 国立大学法人京都大学 | 新規腎前駆細胞マーカーおよびそれを利用した腎前駆細胞の濃縮方法 |
| JP7700673B2 (ja) | 2019-05-15 | 2025-07-01 | 味の素株式会社 | 神経堤細胞または角膜上皮細胞の純化方法 |
| EP3974519A4 (en) | 2019-05-20 | 2023-07-12 | Ajinomoto Co., Inc. | EXPANSION CULTURE METHOD FOR CARTILAGE OR BONE PRECURSOR CELLS |
| CA3152504A1 (en) | 2019-09-06 | 2021-03-11 | Keio University | Method for producing cell aggregate including glial progenitor cells |
| CN118726239A (zh) | 2019-10-01 | 2024-10-01 | 国立大学法人京都大学 | 输尿管芽顶端部细胞的分离方法 |
| WO2021187602A1 (ja) | 2020-03-19 | 2021-09-23 | 国立大学法人京都大学 | 心筋細胞の精製方法 |
| KR102949854B1 (ko) | 2020-03-19 | 2026-04-07 | 오리즈루 세라퓨틱스 가부시키가이샤 | 심근세포 정제 방법 |
| US20230256024A1 (en) | 2020-07-13 | 2023-08-17 | Kyoto University | Skeletal muscle precursor cells and method for purifying same, composition for treating myogenic diseases, and method for producing cell group containing skeletal muscle precursor cells |
| WO2022149616A1 (ja) | 2021-01-08 | 2022-07-14 | 国立大学法人京都大学 | ネフロン前駆細胞を拡大培養するための培地、ネフロン前駆細胞を拡大培養する方法、腎臓オルガノイドの製造方法 |
| CA3222761A1 (en) | 2021-06-10 | 2022-12-15 | Ajinomoto Co., Inc. | Method for producing mesenchymal stem cells |
| AU2022294563A1 (en) | 2021-06-17 | 2024-01-18 | Kyoto University | Method for producing cerebral cortical cell preparation derived from human pluripotent stem cells |
| US20240240157A1 (en) | 2021-07-15 | 2024-07-18 | Cellfiber Co., Ltd. | Structure and Use Thereof |
| JPWO2023017848A1 (enExample) | 2021-08-11 | 2023-02-16 | ||
| JPWO2023149407A1 (enExample) | 2022-02-01 | 2023-08-10 | ||
| EP4477746A4 (en) | 2022-02-09 | 2026-02-18 | Racthera Co Ltd | METHOD FOR EVALUATING THE DIFFERENTIATION POTENTIAL OF CELLS IN A CULTURE BROTH IN THE DIFFERENCE OF MULTIPOTENTED STEM CELLS INTO NEURAL CELLS OF THE MENSCEPHAL FLOOR PLAQUE REGION |
| JPWO2023228908A1 (enExample) | 2022-05-23 | 2023-11-30 | ||
| US20260097083A1 (en) | 2022-09-26 | 2026-04-09 | Kyoto University | Method for producing pancreatic endoderm cells |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5470881A (en) * | 1993-09-09 | 1995-11-28 | West Virginia University Research Corporation | Urea ophthalmic ointment and solution |
| CA2149528A1 (en) * | 1993-09-29 | 1995-04-06 | Billie M. York | Compositions containing growth factors and antimetabolites |
| US5449671A (en) * | 1993-09-29 | 1995-09-12 | Alcon Laboratories, Inc. | Use of TGF-β3, to prevent or retard fistula closure following glaucoma filtration surgery |
| EP0670733A1 (en) * | 1993-09-29 | 1995-09-13 | Alcon Laboratories, Inc. | Compositions containing growth factors and antiplastic agents |
| US5486534A (en) * | 1994-07-21 | 1996-01-23 | G. D. Searle & Co. | 3,4-substituted pyrazoles for the treatment of inflammation |
| US6063396A (en) * | 1994-10-26 | 2000-05-16 | Houston Biotechnology Incorporated | Methods and compositions for the modulation of cell proliferation and wound healing |
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| AU2002357003A1 (en) * | 2001-12-28 | 2003-07-24 | Guilford Pharmaceuticals Inc. | Indoles as naaladase inhibitors |
| AR039241A1 (es) * | 2002-04-04 | 2005-02-16 | Biogen Inc | Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos |
| US7361669B2 (en) * | 2003-01-02 | 2008-04-22 | Millennium Pharmaceuticals, Inc. | Compositions and method for inhibiting TGF-β |
| US7189733B2 (en) * | 2003-03-12 | 2007-03-13 | Millennium Pharmaceuticals, Inc. | Compositions and methods for inhibiting TGF-β |
| EP1633718B1 (en) * | 2003-06-17 | 2012-06-06 | Millennium Pharmaceuticals, Inc. | COMPOSITIONS AND METHODS FOR INHIBITING TGF-s |
| KR100749566B1 (ko) * | 2004-04-21 | 2007-08-16 | 이화여자대학교 산학협력단 | Alk5 및/또는 alk4 억제제로 유효한 2-피리딜이치환된 이미다졸 유도체 |
| US7098222B2 (en) * | 2004-05-12 | 2006-08-29 | Abbott Laboratories | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
| US20050256118A1 (en) * | 2004-05-12 | 2005-11-17 | Altenbach Robert J | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
| US20060234911A1 (en) * | 2005-03-24 | 2006-10-19 | Hoffmann F M | Method of reversing epithelial mesenchymal transition |
| WO2007070866A2 (en) * | 2005-12-16 | 2007-06-21 | Alcon, Inc. | Control of intraocular pressure using alk5 modulation agents |
| EP2044056B1 (en) * | 2006-07-14 | 2012-08-22 | Novartis AG | Pyrimidine derivatives as alk-5 inhibitors |
| US7524640B2 (en) * | 2006-08-06 | 2009-04-28 | Children's Medical Center Corporation | Inhibiting Smad2/3 signaling promotes neurite outgrowth in dorsal root ganglia |
-
2009
- 2009-05-29 CN CN2009801199382A patent/CN102083439A/zh active Pending
- 2009-05-29 WO PCT/US2009/045607 patent/WO2009146408A1/en not_active Ceased
- 2009-05-29 US US12/474,370 patent/US20100087486A1/en not_active Abandoned
- 2009-05-29 EP EP09755769A patent/EP2285380A4/en not_active Withdrawn
- 2009-05-29 JP JP2011511843A patent/JP2011521969A/ja active Pending
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