JP2007515470A5 - - Google Patents

Download PDF

Info

Publication number
JP2007515470A5
JP2007515470A5 JP2006546389A JP2006546389A JP2007515470A5 JP 2007515470 A5 JP2007515470 A5 JP 2007515470A5 JP 2006546389 A JP2006546389 A JP 2006546389A JP 2006546389 A JP2006546389 A JP 2006546389A JP 2007515470 A5 JP2007515470 A5 JP 2007515470A5
Authority
JP
Japan
Prior art keywords
assembly
component
net charge
microvesicle
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006546389A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007515470A (ja
JP5513708B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2004/004230 external-priority patent/WO2005063305A1/en
Publication of JP2007515470A publication Critical patent/JP2007515470A/ja
Publication of JP2007515470A5 publication Critical patent/JP2007515470A5/ja
Application granted granted Critical
Publication of JP5513708B2 publication Critical patent/JP5513708B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2006546389A 2003-12-22 2004-12-21 造影イメージング用の気体封入マイクロベシクル・アセンブリー Expired - Fee Related JP5513708B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03029534 2003-12-22
EP03029534.9 2003-12-22
PCT/IB2004/004230 WO2005063305A1 (en) 2003-12-22 2004-12-21 Gas-filled microvesicle assembly for contrast imaging

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011237685A Division JP2012051932A (ja) 2003-12-22 2011-10-28 造影イメージング用の気体封入マイクロベシクル・アセンブリー

Publications (3)

Publication Number Publication Date
JP2007515470A JP2007515470A (ja) 2007-06-14
JP2007515470A5 true JP2007515470A5 (https=) 2007-12-27
JP5513708B2 JP5513708B2 (ja) 2014-06-04

Family

ID=34717195

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006546389A Expired - Fee Related JP5513708B2 (ja) 2003-12-22 2004-12-21 造影イメージング用の気体封入マイクロベシクル・アセンブリー
JP2011237685A Pending JP2012051932A (ja) 2003-12-22 2011-10-28 造影イメージング用の気体封入マイクロベシクル・アセンブリー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011237685A Pending JP2012051932A (ja) 2003-12-22 2011-10-28 造影イメージング用の気体封入マイクロベシクル・アセンブリー

Country Status (9)

Country Link
US (1) US9750821B2 (https=)
EP (1) EP1701745B1 (https=)
JP (2) JP5513708B2 (https=)
CN (1) CN100563718C (https=)
AU (1) AU2004308756B2 (https=)
CA (1) CA2547024C (https=)
ES (1) ES2531732T3 (https=)
NO (1) NO338316B1 (https=)
WO (1) WO2005063305A1 (https=)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
JP2007515471A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー
CN100563718C (zh) 2003-12-22 2009-12-02 伯拉考开发股份有限公司 用于反差成像的充气微囊组件
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
ATE469660T1 (de) 2006-09-05 2010-06-15 Bracco Research Sa Gasgefüllte mikrovesikel mit polymer- modifizierten lipiden
WO2009091927A1 (en) * 2008-01-15 2009-07-23 Eugene Tu Ultrasonically active microparticles and method of use
US20090234231A1 (en) * 2008-03-13 2009-09-17 Knight Jon M Imaging Catheter With Integrated Contrast Agent Injector
CA2748995C (en) 2008-10-07 2018-01-16 Bracco Suisse Sa Targeting construct comprising anti-polymer antibody and liposomes or microvesicles binding to the same
HUE037082T2 (hu) 2008-11-10 2018-08-28 Arbutus Biopharma Corp Új lipidek és készítmények terápiás hatóanyagok szállítására
CN101745126B (zh) * 2008-12-10 2012-04-25 温州医学院 一种包载水溶性药物超声造影剂的制备方法
EP2470287A4 (en) 2009-08-28 2015-01-21 Univ Columbia SYSTEMS, METHODS AND DEVICES FOR PRODUCING GAS-FILLED MICROBUBBLES
EP2477550A4 (en) 2009-09-15 2013-12-04 Univ Columbia SYSTEMS, METHODS AND DEVICES FOR MICROBUBBLES
CN101773675B (zh) * 2010-03-05 2012-05-30 中山大学 一种负载液态氟碳的聚合物纳米超声显像囊泡及其制备方法
WO2011130658A1 (en) * 2010-04-16 2011-10-20 University Of Pittsburgh -Of The Commonwealth System Of Higher Education Custom designed microbubble contrast agents and techniques of ultrasound delivery optimized for nucleic acid delivery to alter gene expression
TW201208706A (en) 2010-08-17 2012-03-01 Univ Nat Yang Ming Ultrasonically-triggered drug vehicle with magnetic resonance imaging function
WO2012030675A1 (en) * 2010-08-28 2012-03-08 The Trustees Of Columbia University In The City Of New York Systems, methods, and devices for plasmid gene transfection using polymer-modified microbubbles
BR112014014412A2 (pt) 2011-12-16 2017-06-13 Nanobiotix nanopartículas compreendendo materiais metálicos e de óxido de háfnio, sua preparação e uso
US10357450B2 (en) 2012-04-06 2019-07-23 Children's Medical Center Corporation Process for forming microbubbles with high oxygen content and uses thereof
US20150087624A1 (en) * 2012-04-24 2015-03-26 Osaka University Method for producing an aqueous dispersion of drug nanoparticles and use thereof
WO2014065513A1 (ko) * 2012-10-25 2014-05-01 서강대학교 산학협력단 약물을 함유한 나노입자가 결합된 초음파 조영제 및 이의 제조방법
EP2934740B1 (en) 2012-12-21 2019-12-11 Bracco Suisse SA Gas-filled microvesicles
WO2014144364A1 (en) 2013-03-15 2014-09-18 Children's Medical Center Corporation Gas-filled stabilized particles and methods of use
JP6387400B2 (ja) * 2013-05-30 2018-09-05 ナノビオティックスＮａｎｏｂｉｏｔｉｘ 医薬組成物、その製造および使用
KR101595795B1 (ko) * 2014-03-19 2016-02-22 (주)아이엠지티 약물을 함유한 나노입자가 결합된 이중-목적 paｔ／초음파 조영제 및 이의 제조방법
CN104337766A (zh) * 2014-10-09 2015-02-11 唐春林 一种地高辛脂质微泡及其制备方法
WO2016083331A1 (en) 2014-11-25 2016-06-02 Nanobiotix Pharmaceutical composition, preparation and uses thereof
HK1245086A1 (zh) 2014-11-25 2018-08-24 Nanobiotix 处方药物组成及其制备和使用
KR102666251B1 (ko) * 2014-11-25 2024-05-27 큐라디즘 약학적 조성물, 이의 제조 및 용도
DK3223796T3 (da) 2014-11-25 2021-09-27 Curadigm Sas Farmaceutiske sammensætninger, fremstilling og anvendelser deraf
ES2951598T3 (es) 2014-11-25 2023-10-23 Curadigm Sas Composición farmacéutica que combina al menos dos nanopartículas distintas y un compuesto farmacéutico, preparación y usos de los mismos
EP3240579B1 (en) 2014-12-31 2022-07-27 Lantheus Medical Imaging, Inc. Lipid-encapsulated gas microsphere compositions and related methods
MA43100A (fr) 2015-05-28 2018-09-05 Nanobiotix Nanoparticules à utiliser en tant que vaccin thérapeutique
JP2019503403A (ja) * 2016-02-01 2019-02-07 トラスト バイオソニックス インクＴｒｕｓｔ Ｂｉｏｓｏｎｉｃｓ Ｉｎｃ． 脂質組成のマイクロバブル及びその製造方法
MX2018013409A (es) 2016-05-04 2019-07-08 Lantheus Medical Imaging Inc Métodos y dispositivos para la preparación de agentes de contraste de ultrasonido.
US9789210B1 (en) * 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
NO342271B1 (en) * 2016-09-29 2018-04-30 Sintef Tto As A new drug delivery system for treatment of cancer
US11147890B2 (en) 2017-02-28 2021-10-19 Children's Medical Center Corporation Stimuli-responsive particles encapsulating a gas and methods of use
JP7227694B2 (ja) * 2017-12-08 2023-02-22 大平 猛 正に帯電したナノバブル分散液
ES2984146T3 (es) 2018-12-21 2024-10-29 Bracco Suisse Sa Microvesículas llenas de gas con ligando
US20200360289A1 (en) * 2019-05-15 2020-11-19 Bracco Suisse Sa Freeze-dried product and gas-filled microvesicles suspension
CN115734786A (zh) * 2020-06-15 2023-03-03 博莱科瑞士股份有限公司 超声介导治疗的改进

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2647121A (en) * 1951-02-02 1953-07-28 Ruth P Jacoby Diamine-bis-acetamides
US2819718A (en) * 1953-07-16 1958-01-14 Isidore H Goldman Drainage tube
US2844629A (en) * 1956-04-25 1958-07-22 American Home Prod Fatty acid amides and derivatives thereof
US3096560A (en) * 1958-11-21 1963-07-09 William J Liebig Process for synthetic vascular implants
JPS5141663B1 (https=) * 1966-03-12 1976-11-11
NL143127B (nl) * 1969-02-04 1974-09-16 Rhone Poulenc Sa Versterkingsorgaan voor een defecte hartklep.
US3614954A (en) * 1970-02-09 1971-10-26 Medtronic Inc Electronic standby defibrillator
US3614955A (en) * 1970-02-09 1971-10-26 Medtronic Inc Standby defibrillator and method of operation
US3945052A (en) * 1972-05-01 1976-03-23 Meadox Medicals, Inc. Synthetic vascular graft and method for manufacturing the same
US3805301A (en) * 1972-07-28 1974-04-23 Meadox Medicals Inc Tubular grafts having indicia thereon
US4013507A (en) * 1973-09-18 1977-03-22 California Institute Of Technology Ionene polymers for selectively inhibiting the vitro growth of malignant cells
US3995623A (en) * 1974-12-23 1976-12-07 American Hospital Supply Corporation Multipurpose flow-directed catheter
US4281669A (en) * 1975-05-09 1981-08-04 Macgregor David C Pacemaker electrode with porous system
US4096860A (en) * 1975-10-08 1978-06-27 Mclaughlin William F Dual flow encatheter
CA1069652A (en) * 1976-01-09 1980-01-15 Alain F. Carpentier Supported bioprosthetic heart valve with compliant orifice ring
US4134402A (en) * 1976-02-11 1979-01-16 Mahurkar Sakharam D Double lumen hemodialysis catheter
US4072146A (en) * 1976-09-08 1978-02-07 Howes Randolph M Venous catheter device
US4335723A (en) * 1976-11-26 1982-06-22 The Kendall Company Catheter having inflatable retention means
US4099528A (en) * 1977-02-17 1978-07-11 Sorenson Research Co., Inc. Double lumen cannula
US4140126A (en) * 1977-02-18 1979-02-20 Choudhury M Hasan Method for performing aneurysm repair
US4182833A (en) * 1977-12-07 1980-01-08 Celanese Polymer Specialties Company Cationic epoxide-amine reaction products
US4180068A (en) * 1978-04-13 1979-12-25 Motion Control, Incorporated Bi-directional flow catheter with retractable trocar/valve structure
EP0005035B1 (en) * 1978-04-19 1981-09-23 Imperial Chemical Industries Plc A method of preparing a tubular product by electrostatic spinning
US4284459A (en) * 1978-07-03 1981-08-18 The Kendall Company Method for making a molded catheter
US4227533A (en) * 1978-11-03 1980-10-14 Bristol-Myers Company Flushable urinary catheter
US4276885A (en) 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4339369A (en) * 1981-04-23 1982-07-13 Celanese Corporation Cationic epoxide-amine reaction products
DE3463211D1 (en) 1983-07-01 1987-05-21 Battelle Memorial Institute Biodegradable polypeptide and its use in the sustained release of medicaments
SE463651B (sv) 1983-12-21 1991-01-07 Nycomed As Diagnostikum och kontrastmedel
ATE60340T1 (de) 1984-10-19 1991-02-15 Battelle Memorial Institute Durch mikroorganismen abbaubares polypeptid und seine verwendung fuer die fortschreitende abgabe von medikamenten.
CH667874A5 (fr) 1985-12-19 1988-11-15 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
IE61591B1 (en) 1987-12-29 1994-11-16 Molecular Biosystems Inc Concentrated stabilized microbubble-type ultrasonic imaging agent and method of production
US5733572A (en) 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US5580575A (en) 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US6146657A (en) 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
US5776429A (en) 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5445813A (en) 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
IN172208B (https=) * 1990-04-02 1993-05-01 Sint Sa
US20080063603A1 (en) 1990-04-02 2008-03-13 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5556610A (en) 1992-01-24 1996-09-17 Bracco Research S.A. Gas mixtures useful as ultrasound contrast media, contrast agents containing the media and method
AU636481B2 (en) 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
US5487390A (en) 1990-10-05 1996-01-30 Massachusetts Institute Of Technology Gas-filled polymeric microbubbles for ultrasound imaging
US5562099A (en) * 1990-10-05 1996-10-08 Massachusetts Institute Of Technology Polymeric microparticles containing agents for imaging
JP2974083B2 (ja) 1990-11-26 1999-11-08 株式会社 小松製作所 静油圧―機械式伝動機の制御装置
CA2112905A1 (en) 1991-07-05 1993-01-21 Michael R. Violante Ultrasmall non-aggregated porous particles entrapping gas-bubbles
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
DE4208527A1 (de) * 1992-03-17 1993-09-23 Max Planck Gesellschaft Liposomen mit negativer ueberschussladung
AU4563093A (en) 1992-07-03 1994-01-31 Byk Gulden Lomberg Chemische Fabrik Gmbh Echographic contrast agent composition
US5464696A (en) 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
EP1550464A1 (en) 1993-07-30 2005-07-06 IMCOR Pharmaceutical Co. Stabilized microbubble composition for ultrasound
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
CN1068229C (zh) 1993-12-15 2001-07-11 勃勒柯研究有限公司 超声对比介质、含该介质的对比剂及方法
NO940711D0 (no) 1994-03-01 1994-03-01 Nycomed Imaging As Preparation of gas-filled microcapsules and contrasts agents for diagnostic imaging
US5876697A (en) 1994-08-04 1999-03-02 Gakko Houjin Toin Gakuen Method for the production of microbubble-type ultrasonic contrast agent using fatty acid surfactants
GB9417941D0 (en) 1994-09-06 1994-10-26 Nycomed Imaging As Improvements in or relating to contrast agents
JPH10508578A (ja) 1994-09-23 1998-08-25 ザ リポソーム カンパニー、インコーポレーテッド 凍結乾燥リポソーム生成物の製造方法
US6333021B1 (en) 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
IL116328A (en) 1994-12-16 1999-09-22 Bracco Research Sa Frozen suspension of gas microbubbles in frozen aqueous carrier for use as contrast agent in ultrasonic imaging
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US5833948A (en) 1995-06-15 1998-11-10 Bracco Research S.A. Blood-pool imaging composition comprising micelles containing a lipophilic chelating agent and a non-ionic surfactant
WO1997029782A1 (en) 1996-02-19 1997-08-21 Nycomed Imaging A/S Thermally stabilized contrast agent
US6165442A (en) 1996-02-19 2000-12-26 Nycomed Imaging As Thermally stabilized ultrasound contrast agent
ATE238072T1 (de) 1996-02-19 2003-05-15 Amersham Health As Verbesserungen an (oder im bezug auf) kontrastmittel
GB2330505B (en) 1996-07-22 2001-02-07 Seagate Technology Phase detector estimator
MXPA99001053A (es) 1996-08-02 2002-03-11 Nycomed Imaging As Mejoramientos en o que se relacionan con agentes de contraste.
TR199901544T2 (xx) * 1996-10-21 1999-09-21 Nycomed Imaging As Kontrast ajanlar�ndaki veya kontrast ajanlar�yla ilgili geli�meler.
BR9713978A (pt) 1996-10-28 2000-05-02 Nycomed Imaging As Agente diagnóstico alvejável e/ou terapeuticamente ativo, processo para preparação e uso do mesmo, formulação combinada, e, processos para gerar imagens intensificadas de um corpo animal humano ou não-humano e para investigação in vitro de alvejamento por um agente
US6331289B1 (en) 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
EP0973552B1 (en) 1996-10-28 2006-03-01 Amersham Health AS Improvements in or relating to diagnostic/therapeutic agents
GB9701237D0 (en) 1997-01-22 1997-03-12 Nycomed Imaging As Improvements in or relating to contrast agents
US6143276A (en) 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US6245318B1 (en) 1997-05-27 2001-06-12 Mallinckrodt Inc. Selectively binding ultrasound contrast agents
GB9717589D0 (en) 1997-08-19 1997-10-22 Nycomed Imaging As Improvements in or relating to contrast agents
WO1999020312A1 (en) 1997-10-21 1999-04-29 Nycomed Imaging As Ultrasound imaging with contrast agent targeted to microvasculature and a vasodilator drug
US20020169138A1 (en) * 1997-10-24 2002-11-14 Southern Research Institute Delivery vehicles for bioactive agents and uses thereof
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
ES2244169T3 (es) 1998-02-09 2005-12-01 Bracco International B.V. Suministro direccionado de medios biologicamente activos.
GB9808599D0 (en) 1998-04-22 1998-06-24 Nycomed Imaging As Improvements in or realting to contrast agents
GB9809084D0 (en) 1998-04-28 1998-06-24 Nycomed Imaging As Improvements in or relating to diagnostic/therapeutic agents
FR2782006B1 (fr) 1998-08-07 2002-04-19 Gattefosse Ets Sa Composition a liberation prolongee apte a former une micro-emulsion
JP2000143550A (ja) * 1998-11-10 2000-05-23 Toin Gakuen 超音波造影剤
DE10013850A1 (de) 2000-03-15 2001-09-20 Schering Ag Gasgefüllte Mikrokapseln enthaltend funktionalisiertes Polyalkylcyanacrylat, sowie Verfahren zu deren Herstellung
WO2002055544A2 (en) 2000-12-23 2002-07-18 Dyax Corp Fibrin binding polypeptides useful inter alia in medical imaging processes
JP2002212108A (ja) 2001-01-17 2002-07-31 Fuji Photo Film Co Ltd 超音波散乱体
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
US7179449B2 (en) 2001-01-30 2007-02-20 Barnes-Jewish Hospital Enhanced ultrasound detection with temperature-dependent contrast agents
DE60111917T2 (de) 2001-01-31 2006-04-20 Bracco International B.V. Lyophilisierbares Kontrastmittel, gasgefüllte Mikrobläschen enthaltend
AU2002317095A1 (en) * 2001-07-03 2003-01-21 Governors Of The University Of Alberta Magnetic nanoparticles for bioseparation application and methods for producing same
CA2456988A1 (en) * 2001-08-16 2003-02-27 Alan P. Carpenter, Jr. Gas microsphere liposome composites
SI1482987T1 (sl) 2002-03-01 2014-12-31 Bracco Suisse Sa Večvalentni konstrukti za terapevtske in diagnostične aplikacije
CA2666005C (en) 2002-03-01 2016-01-19 Dyax Corp. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
CN100347380C (zh) 2002-06-19 2007-11-07 迪米特里奥斯·帕特萨拉里迪斯 在地面中锚定的支撑装置
AU2003303954A1 (en) * 2002-10-25 2004-10-11 Emory University Multifunctional magnetic nanoparticle probes for intracellular molecular imaging and monitoring
JP4670083B2 (ja) 2003-02-04 2011-04-13 ブラッコ・シュイス・ソシエテ・アノニム 超音波造影剤およびその製造方法
CA2543296A1 (en) 2003-10-31 2005-05-12 Point Biomedical Corporation Reconstitutable microsphere compositions useful as ultrasonic contrast agents
CN100563718C (zh) 2003-12-22 2009-12-02 伯拉考开发股份有限公司 用于反差成像的充气微囊组件
JP2007515471A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー
ATE466596T1 (de) 2004-01-20 2010-05-15 Sunnybrook & Womens College Hochfrequenz-ultraschall-darstellung mit kontrastmitteln
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging

Similar Documents

Publication Publication Date Title
JP2007515470A5 (https=)
JP2007515471A5 (https=)
JP7355394B2 (ja) カロテノイド組成物およびその使用
Jadhav et al. Novel vesicular system: an overview
KR100508695B1 (ko) 인슐린의 경구투여용 제형과 그의 제조방법
Rajera et al. Niosomes: a controlled and novel drug delivery system
KR101198715B1 (ko) 핵산 및 친수성 음이온 화합물의 고효율 포획을 위한 비대칭 리포솜 및 이의 제조방법
Arunagirinathan et al. Self-assembled surfactant nano-structures important in drug delivery: a review
ES2336766T3 (es) Procedimiento de recubrimiento de particulas finas con pelicula lipidica.
ES2643938T3 (es) Liposoma transpulmonar para controlar la llegada del fármaco
JP5627039B2 (ja) 薬物のナノ分散体およびその調製のための方法
JP2010532786A5 (https=)
JP2003526679A (ja) 各種物質の可溶化用組成物と剤形及びそれらの製造方法
JP2007510657A5 (https=)
BE1022346B1 (fr) Compositions liposomales pour une administration mucosale
US20190328665A1 (en) Liposome compositions encapsulating modified cyclodextrin complexes and uses thereof
Maheswaran et al. Liposomal drug delivery systems—a review
JP2010518012A (ja) カンプトテシン誘導体を含む医薬組成物
Nemr et al. A comprehensive review on bilosome: a nano-vesicular drug delivery system to enhance bioavailability of the drug through different routes of administration
Reddy et al. Niosomes as nanocarrier systems: a review
Benedini et al. Proniosomes and niosomes for enhanced drug delivery
Matole et al. Need of liposomes as a novel drug delivery system
JPWO2019045897A5 (https=)
Ghode et al. Applications perspectives of emulsomes drug delivery system
JP3620059B2 (ja) 反応性小胞体、形成剤および機能性物質固定化小胞体