|
US3485852A
(en)
|
1958-11-13 |
1969-12-23 |
Syntex Corp |
6-halo-6-dehydro-progesterones
|
|
US3120551A
(en)
*
|
1961-03-20 |
1964-02-04 |
Warner Lambert Pharmaceutical |
5-(4-biphenylyl)-3-methylvaleric acid and functional derivatives thereof
|
|
DE1158966B
(de)
|
1961-04-29 |
1963-12-12 |
Schering Ag |
Verfahren zur Herstellung von 6-Chlor-1, 2ª-methylen-í¸-17ª-hydroxyprogesteronestern
|
|
BE637389A
(enExample)
|
1962-09-13 |
|
|
|
|
US3357887A
(en)
*
|
1962-12-03 |
1967-12-12 |
Upjohn Co |
4-phenoxy-3, 5-dihalophenylalkanols and hypocholesteremic compositions containing the same
|
|
FR1356282A
(fr)
|
1963-01-09 |
1964-03-27 |
Nobel Bozel |
Procédé pour rendre rigides les cannelures de cartons ondulés
|
|
US3536809A
(en)
|
1969-02-17 |
1970-10-27 |
Alza Corp |
Medication method
|
|
US3598123A
(en)
|
1969-04-01 |
1971-08-10 |
Alza Corp |
Bandage for administering drugs
|
|
US3822287A
(en)
|
1969-04-17 |
1974-07-02 |
Rexall Drug Chemical |
Process for preparation of substituted 3,4-(diphenyl)chromans
|
|
US3683080A
(en)
|
1970-08-28 |
1972-08-08 |
Procter & Gamble |
Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue
|
|
US3692895A
(en)
|
1970-09-08 |
1972-09-19 |
Norman A Nelson |
Method of reducing hypercholesteremia in humans employing a copolymer of polyethylenepolyamine and a bifunctional substance, such as epichlorohydria
|
|
US3847988A
(en)
|
1971-12-23 |
1974-11-12 |
Schering Corp |
Substituted imidates
|
|
US3845770A
(en)
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US4069343A
(en)
*
|
1973-03-23 |
1978-01-17 |
American Home Products Corporation |
Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions
|
|
US3916899A
(en)
|
1973-04-25 |
1975-11-04 |
Alza Corp |
Osmotic dispensing device with maximum and minimum sizes for the passageway
|
|
JPS5612114B2
(enExample)
|
1974-06-07 |
1981-03-18 |
|
|
|
FR2329276A1
(fr)
|
1975-10-29 |
1977-05-27 |
Roussel Uclaf |
Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
|
|
US4008719A
(en)
|
1976-02-02 |
1977-02-22 |
Alza Corporation |
Osmotic system having laminar arrangement for programming delivery of active agent
|
|
US4069347A
(en)
*
|
1976-08-02 |
1978-01-17 |
Emery Industries, Inc. |
Compositions of quaternary ammonium derivatives of lanolin acids
|
|
JPS608117B2
(ja)
|
1977-02-08 |
1985-02-28 |
財団法人微生物化学研究会 |
新生理活性物質エステラスチンおよびその製造法
|
|
DE2860900D1
(en)
|
1977-08-22 |
1981-11-05 |
Ici Plc |
Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
|
|
CA1121290A
(en)
|
1978-02-14 |
1982-04-06 |
Yasuji Suhara |
Amino sugar derivatives
|
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
|
DE2928485A1
(de)
|
1979-07-14 |
1981-01-29 |
Bayer Ag |
Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
|
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
MX7065E
(es)
|
1980-06-06 |
1987-04-10 |
Sankyo Co |
Un procedimiento microbiologico para preparar derivados de ml-236b
|
|
US4450171A
(en)
|
1980-08-05 |
1984-05-22 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4426453A
(en)
*
|
1980-09-18 |
1984-01-17 |
Amersham International Limited |
Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds
|
|
DE3037858A1
(de)
*
|
1980-10-07 |
1982-05-19 |
Boehringer Mannheim Gmbh, 6800 Mannheim |
Verfahren zur herstellung von reaktiven, kupplungsfaehigen derivaten der schilddruesenhormone t (pfeil abwaerts)3(pfeil abwaerts) und t (pfeil abwaerts)4(pfeil abwaerts) und deren verwendung
|
|
ES8207217A1
(es)
|
1980-10-09 |
1982-09-01 |
Hoechst Ag |
Procedimiento para la preparacion de un inactivador de alfa-amilasa
|
|
US4418068A
(en)
|
1981-04-03 |
1983-11-29 |
Eli Lilly And Company |
Antiestrogenic and antiandrugenic benzothiophenes
|
|
US4452813A
(en)
|
1981-05-22 |
1984-06-05 |
Taiho Pharmaceutical Company Limited |
Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
|
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
3−ヒドロキシ−ml−236b誘導体の製造法
|
|
GB2126576B
(en)
|
1982-06-25 |
1985-06-19 |
Farmos Group Limited |
Alkane and alkene derivatives
|
|
EP0100172B1
(en)
|
1982-07-23 |
1987-08-12 |
Imperial Chemical Industries Plc |
Amide derivatives
|
|
US4739073A
(en)
|
1983-11-04 |
1988-04-19 |
Sandoz Pharmaceuticals Corp. |
Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
|
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
|
US4554290A
(en)
*
|
1983-06-17 |
1985-11-19 |
Ciba-Geigy Corporation |
Oxamic acid derivatives
|
|
CA1247547A
(en)
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Leucine derivatives
|
|
CA1327360C
(en)
|
1983-11-14 |
1994-03-01 |
William F. Hoffman |
Oxo-analogs of mevinolin-like antihypercholesterolemic agents
|
|
DK520784A
(da)
|
1984-01-21 |
1985-07-22 |
Hoechst Ag |
Cycliske polypeptider, deres fremstilling og anvendelse
|
|
US4686237A
(en)
|
1984-07-24 |
1987-08-11 |
Sandoz Pharmaceuticals Corp. |
Erythro-(E)-7-[3'-C1-3 alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl]-3,5-dihydroxyhept-6-enoic acids and derivatives thereof
|
|
US4647576A
(en)
|
1984-09-24 |
1987-03-03 |
Warner-Lambert Company |
Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
|
|
IE58110B1
(en)
|
1984-10-30 |
1993-07-14 |
Elan Corp Plc |
Controlled release powder and process for its preparation
|
|
US4673691A
(en)
*
|
1984-11-05 |
1987-06-16 |
Nicholas Bachynsky |
Human weight loss inducing method
|
|
WO1986003488A1
(en)
|
1984-12-04 |
1986-06-19 |
Sandoz Ag |
Indene analogs of mevalonolactone and derivatives thereof
|
|
US5061798A
(en)
*
|
1985-01-18 |
1991-10-29 |
Smith Kline & French Laboratories, Ltd. |
Benzyl pyridyl and pyridazinyl compounds
|
|
GB8501372D0
(en)
*
|
1985-01-18 |
1985-02-20 |
Smith Kline French Lab |
Chemical compounds
|
|
US4668794A
(en)
|
1985-05-22 |
1987-05-26 |
Sandoz Pharm. Corp. |
Intermediate imidazole acrolein analogs
|
|
HUT48208A
(en)
|
1985-10-25 |
1989-05-29 |
Sandoz Ag |
Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds
|
|
US4847271A
(en)
|
1986-01-27 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
|
US4968788A
(en)
|
1986-04-04 |
1990-11-06 |
Board Of Regents, The University Of Texas System |
Biologically reversible phosphate and phosphonate protective gruops
|
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
|
US5091552A
(en)
|
1986-06-30 |
1992-02-25 |
Board Of Regents, The University Of Texas System |
Novel antitumor aldophosphamide analogs
|
|
US5138069A
(en)
|
1986-07-11 |
1992-08-11 |
E. I. Du Pont De Nemours And Company |
Angiotensin II receptor blocking imidazoles
|
|
GB2196003A
(en)
|
1986-09-11 |
1988-04-20 |
Nat Res Dev |
Iodo-and bromo-tamoxifen derivatives
|
|
US5041432A
(en)
|
1987-01-30 |
1991-08-20 |
E. I. Du Pont De Nemours And Company |
Steroid derivatives useful as hypocholesterolemics
|
|
US5110940A
(en)
|
1987-02-25 |
1992-05-05 |
Bristol-Myers Company |
Antihypercholesterolemic tetrazole compounds
|
|
DE3718638A1
(de)
*
|
1987-06-04 |
1988-12-22 |
Thomae Gmbh Dr K |
Neue phenylethanolamine, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
|
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
|
US4929600A
(en)
|
1988-03-18 |
1990-05-29 |
University Of Deleware |
Endocrine manipulation to improve body composition of poultry
|
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US5049696A
(en)
|
1988-04-11 |
1991-09-17 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
|
US5073543A
(en)
|
1988-07-21 |
1991-12-17 |
G. D. Searle & Co. |
Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
|
|
US4866058A
(en)
|
1988-07-27 |
1989-09-12 |
Izydore Robert A |
Method for control of hyperlipidemia
|
|
IT1226726B
(it)
|
1988-07-29 |
1991-02-05 |
Zambon Spa |
Composti attivi come inibitori della biosintesi del colesterolo.
|
|
US5196440A
(en)
|
1988-07-29 |
1993-03-23 |
Zambon Group S.P.A. |
Compounds active as inhibitors of the cholesterol biosynthesis
|
|
US5011947A
(en)
|
1988-08-25 |
1991-04-30 |
Bristol-Myers |
Antihypercholesterolemic alkylene compounds
|
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
|
US5658889A
(en)
|
1989-01-24 |
1997-08-19 |
Gensia Pharmaceuticals, Inc. |
Method and compounds for aica riboside delivery and for lowering blood glucose
|
|
US5166364A
(en)
|
1989-02-27 |
1992-11-24 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
US5099035A
(en)
|
1989-02-27 |
1992-03-24 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
IT1229203B
(it)
|
1989-03-22 |
1991-07-25 |
Bioresearch Spa |
Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
|
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
|
US5010105A
(en)
|
1989-06-09 |
1991-04-23 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
US5106992A
(en)
|
1989-07-28 |
1992-04-21 |
E. R. Squibb & Sons, Inc. |
3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
US4970221A
(en)
|
1989-07-28 |
1990-11-13 |
E. R. Squibb & Sons, Inc. |
3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
US5064856A
(en)
|
1989-07-31 |
1991-11-12 |
Merck & Co., Inc. |
Novel hmg-coa synthase inhibitors
|
|
US5025017A
(en)
|
1989-09-28 |
1991-06-18 |
E. R. Squibb & Sons, Inc. |
Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
|
|
US5189180A
(en)
|
1989-09-28 |
1993-02-23 |
E. R. Squibb & Sons, Inc. |
Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates
|
|
US5217992A
(en)
|
1989-10-04 |
1993-06-08 |
Bristol-Myers Squibb Company |
Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
|
|
US5120738A
(en)
|
1989-10-06 |
1992-06-09 |
Fujirebio Inc. |
Pantothenic acid derivatives
|
|
US5116828A
(en)
*
|
1989-10-26 |
1992-05-26 |
Nippon Zoki Pharmaceutical Co., Ltd. |
Pharmaceutical composition for treatment of osteoporosis
|
|
IE903851A1
(en)
|
1989-11-03 |
1991-05-08 |
Boots Pharma Inc |
Iodothyronine polymers
|
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
|
US5391571A
(en)
|
1989-11-15 |
1995-02-21 |
American Home Products Corporation |
Cholesterol ester hydrolase inhibitors
|
|
EP0433983B1
(en)
|
1989-12-20 |
1998-03-04 |
Texas Instruments Incorporated |
Copper etch process using halides
|
|
IT1237793B
(it)
|
1989-12-21 |
1993-06-17 |
Zambon Spa |
Composti attivi come inibitori dell'enzima hmg-coa reduttasi
|
|
US5049577A
(en)
|
1990-01-29 |
1991-09-17 |
E. R. Squibb & Sons, Inc. |
2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith
|
|
EP0466909B1
(en)
|
1990-02-05 |
1995-06-28 |
British Technology Group (Usa) Incorporated |
Thyroid hormone for cardiac treatment
|
|
US5158978A
(en)
*
|
1990-02-05 |
1992-10-27 |
British Technology Group (U.S.A.) |
Thyroid hormone treatment of acute cardiovascular compromise
|
|
DE59107440D1
(de)
|
1990-02-19 |
1996-04-04 |
Ciba Geigy Ag |
Acylverbindungen
|
|
NZ237476A
(en)
|
1990-03-20 |
1994-01-26 |
Sanofi Sa |
N-substituted heterocyclic compounds and pharmaceutical compositions.
|
|
US5196444A
(en)
|
1990-04-27 |
1993-03-23 |
Takeda Chemical Industries, Ltd. |
1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
|
|
US5733566A
(en)
|
1990-05-15 |
1998-03-31 |
Alkermes Controlled Therapeutics Inc. Ii |
Controlled release of antiparasitic agents in animals
|
|
ATE131825T1
(de)
|
1990-06-13 |
1996-01-15 |
Arnold Glazier |
Phosphorylierte prodrugs
|
|
US5120729A
(en)
|
1990-06-20 |
1992-06-09 |
Merck & Co., Inc. |
Beta-lactams as antihypercholesterolemics
|
|
EP0481214B1
(en)
*
|
1990-09-14 |
1998-06-24 |
Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic |
Prodrugs of phosphonates
|
|
GB9025509D0
(en)
|
1990-11-23 |
1991-01-09 |
Fujisawa Pharmaceutical Co |
New amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
|
|
WO1992009572A1
(en)
|
1990-11-26 |
1992-06-11 |
Taisho Pharmaceutical Co., Ltd. |
Anilide derivative
|
|
US5177080A
(en)
|
1990-12-14 |
1993-01-05 |
Bayer Aktiengesellschaft |
Substituted pyridyl-dihydroxy-heptenoic acid and its salts
|
|
US5614519A
(en)
|
1991-02-06 |
1997-03-25 |
Karl Thomae Gmbh |
(1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
|
|
SI9210098B
(sl)
|
1991-02-06 |
2000-06-30 |
Dr. Karl Thomae |
Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
|
|
IE920540A1
(en)
|
1991-02-21 |
1992-08-26 |
Sankyo Co |
1-biphenylmethylimidazole derivatives, their preparation and¹their therapetuic use
|
|
US5616599A
(en)
|
1991-02-21 |
1997-04-01 |
Sankyo Company, Limited |
Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
|
|
US5157027A
(en)
|
1991-05-13 |
1992-10-20 |
E. R. Squibb & Sons, Inc. |
Bisphosphonate squalene synthetase inhibitors and method
|
|
JP2648897B2
(ja)
|
1991-07-01 |
1997-09-03 |
塩野義製薬株式会社 |
ピリミジン誘導体
|
|
HU217629B
(hu)
|
1991-12-12 |
2000-03-28 |
Novartis Ag. |
Eljárás fluvasztatint tartalmazó stabilizált gyógyszerkészítmények előállítására
|
|
EP0618803A4
(en)
|
1991-12-19 |
1995-03-22 |
Southwest Found Biomed Res |
POLYPEPTIDE INHIBITING PROTEIN TRANSFER TO CHOLESTERYL ESTERS, ANTIBODIES AGAINST SYNTHETIC POLYPEPTIDE AND ANTI-ATHEROSCLEROSIS PROPHYLACTIC AND THERAPEUTIC TREATMENTS.
|
|
US5580578A
(en)
|
1992-01-27 |
1996-12-03 |
Euro-Celtique, S.A. |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
|
|
DK0550108T3
(da)
*
|
1991-12-30 |
1999-01-04 |
Akzo Nobel Nv |
Thyreoaktiv sammensætning med langvarig frigivelse
|
|
US5157134A
(en)
|
1992-03-12 |
1992-10-20 |
E. R. Squibb & Sons, Inc. |
Dihydroxyheptanoic acids containing an oxabicycloheptane nucleus useful as antihypercholesterolemic agents
|
|
SG82630A1
(en)
|
1992-04-20 |
2001-08-21 |
Takeda Chemical Industries Ltd |
4,1-benzoxazepin derivatives and their use
|
|
US5284971A
(en)
*
|
1992-07-16 |
1994-02-08 |
Syntex (U.S.A.) Inc. |
4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents
|
|
DK0580550T3
(da)
*
|
1992-07-21 |
1998-02-02 |
Ciba Geigy Ag |
Oxamidsyrederivater som hypercholesterolæmiske midler
|
|
US5741803A
(en)
*
|
1992-09-05 |
1998-04-21 |
Smithkline Beecham Plc |
Substituted thiazolidinedionle derivatives
|
|
US5591767A
(en)
|
1993-01-25 |
1997-01-07 |
Pharmetrix Corporation |
Liquid reservoir transdermal patch for the administration of ketorolac
|
|
CA2115183A1
(en)
|
1993-02-12 |
1994-08-13 |
Takashi Nomoto |
Substituted amic acid derivatives
|
|
IL108634A0
(en)
|
1993-02-15 |
1994-05-30 |
Wellcome Found |
Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
|
|
IL108633A
(en)
|
1993-02-15 |
1998-07-15 |
Wellcome Found |
History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them
|
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
|
IL109431A
(en)
|
1993-05-14 |
2001-01-11 |
Warner Lambert Co |
Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds
|
|
US5491172A
(en)
|
1993-05-14 |
1996-02-13 |
Warner-Lambert Company |
N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
|
|
US5703188A
(en)
|
1993-06-02 |
1997-12-30 |
Geltex Pharmaceuticals, Inc. |
Process for removing bile salts from a patient and compositions therefor
|
|
FR2705992B1
(fr)
|
1993-06-04 |
1995-07-21 |
Anastasie Maurice Gustave Euge |
Vitrage anti effractions.
|
|
US5571840A
(en)
*
|
1993-06-22 |
1996-11-05 |
The Regents Of The University Of Michigan |
Method for treating central nervous system ischemia
|
|
ATE199906T1
(de)
|
1993-06-29 |
2001-04-15 |
Mitsubishi Chem Corp |
Phosphonat-nukleotid ester-derivate
|
|
JP3286745B2
(ja)
|
1993-09-10 |
2002-05-27 |
日清食品株式会社 |
シクロヘキサンジウレア誘導体及びその製法
|
|
AU678503B2
(en)
|
1993-09-24 |
1997-05-29 |
Takeda Chemical Industries Ltd. |
Condensed heterocyclic compounds and their use as squalene synthetase inhibitors
|
|
US6756388B1
(en)
|
1993-10-12 |
2004-06-29 |
Pfizer Inc. |
Benzothiophenes and related compounds as estrogen agonists
|
|
US5519163A
(en)
*
|
1993-10-15 |
1996-05-21 |
Merck & Co., Inc. |
Inhibitors of phosphoinositide-specific phospholipase C
|
|
GB9401892D0
(en)
*
|
1994-02-01 |
1994-03-30 |
Boots Co Plc |
Therapeutic agents
|
|
WO1995024919A1
(en)
|
1994-03-15 |
1995-09-21 |
K.U. Leuven Research & Development |
New use of growth hormone
|
|
IT1270594B
(it)
|
1994-07-07 |
1997-05-07 |
Recordati Chem Pharm |
Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
|
|
GB9416219D0
(en)
*
|
1994-08-11 |
1994-10-05 |
Karobio Ab |
Receptor ligands
|
|
WO1996009827A2
(en)
|
1994-09-20 |
1996-04-04 |
Pfizer Inc. |
Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor
|
|
JP3720395B2
(ja)
|
1994-09-20 |
2005-11-24 |
京都薬品工業株式会社 |
新規ヘテロ環誘導体、その製造方法およびその医薬用途
|
|
US7501441B1
(en)
|
1994-09-20 |
2009-03-10 |
Eli Lilly And Company |
Naphthyl compounds, intermediates, processes, compositions, and methods
|
|
AU3577995A
(en)
|
1994-10-04 |
1996-04-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Urea derivatives and their use as acat-inhibitors
|
|
TW401301B
(en)
|
1994-10-07 |
2000-08-11 |
Takeda Chemical Industries Ltd |
Antihypertriglyceridemic composition
|
|
JPH08143457A
(ja)
|
1994-11-21 |
1996-06-04 |
Microbial Chem Res Found |
酵素阻害剤および高脂血症抑制剤
|
|
CA2206307A1
(en)
*
|
1994-11-29 |
1996-06-06 |
Dainippon Pharmaceutical Co., Ltd. |
Indole derivative
|
|
US5510379A
(en)
|
1994-12-19 |
1996-04-23 |
Warner-Lambert Company |
Sulfonate ACAT inhibitors
|
|
DE19502209A1
(de)
*
|
1995-01-25 |
1996-08-01 |
Hoechst Ag |
Phosphonoessigsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
|
|
US5510357A
(en)
|
1995-02-28 |
1996-04-23 |
Eli Lilly And Company |
Benzothiophene compounds as anti-estrogenic agents
|
|
GB9504066D0
(en)
|
1995-03-01 |
1995-04-19 |
Pharmacia Spa |
Phosphate derivatives of ureas and thioureas
|
|
JP3144624B2
(ja)
|
1995-06-02 |
2001-03-12 |
杏林製薬株式会社 |
N−ベンジルジオキソチアゾリジルベンズアミド誘導体及びその製造法
|
|
US6380255B1
(en)
*
|
1995-06-07 |
2002-04-30 |
Karo Bio Ab |
Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds
|
|
US6221911B1
(en)
*
|
1995-06-07 |
2001-04-24 |
Karo Bio Ab |
Uses for thyroid hormone compounds or thyroid hormone-like compounds
|
|
US5919795A
(en)
|
1995-06-07 |
1999-07-06 |
Pfizer Inc. |
Biphenyl-2-carboxylic acid-tetrahydro-isoquinolin-6-yl amide derivatives, their preparation and their use as inhibitors of microsomal triglyceride transfer protein and/or apolipoprotein B (Apo B) secretion
|
|
DK0831769T3
(da)
|
1995-06-07 |
2004-02-23 |
Karobio Ab |
Hidtil ukendte anvendelser af thyroideahormoner eller thyroideahormon-lignende forbindelser
|
|
US5780058A
(en)
|
1995-07-21 |
1998-07-14 |
Alza Corporation |
Oral delivery of discrete units
|
|
DE19534996A1
(de)
|
1995-09-21 |
1997-03-27 |
Bosch Gmbh Robert |
Verfahren zur Verbrennungsaussetzererkennung durch Auswertung von Drehzahlschwankungen
|
|
CZ292632B6
(cs)
|
1995-10-05 |
2003-11-12 |
Kyoto Pharmaceutical Industries, Ltd. |
Indolinový, indolový nebo tetrahydrochinolinový derivát a farmaceutický přípravek s jeho obsahem
|
|
FR2741619B1
(fr)
|
1995-11-28 |
1998-02-13 |
Pf Medicament |
Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique
|
|
DE69636677D1
(de)
|
1995-12-13 |
2006-12-14 |
Univ California |
Kristalle der mit einem Ligand komplexierten Ligandenbindedomäne des Schilddrüsenhormonrezeptors
|
|
US6266622B1
(en)
*
|
1995-12-13 |
2001-07-24 |
Regents Of The University Of California |
Nuclear receptor ligands and ligand binding domains
|
|
US6132420A
(en)
|
1996-02-02 |
2000-10-17 |
Alza Corporation |
Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
|
|
CA2197364A1
(en)
|
1996-02-15 |
1997-08-16 |
Toshikazu Suzuki |
Phenol compound and process for preparing the same
|
|
JPH10195037A
(ja)
|
1996-02-15 |
1998-07-28 |
Tanabe Seiyaku Co Ltd |
フェノール誘導体
|
|
US6361992B1
(en)
*
|
1996-05-08 |
2002-03-26 |
The United States Of America As Represented By The Department Of Health And Human Services |
Thyroid stimulating hormone superagonists
|
|
US6017924A
(en)
|
1996-06-27 |
2000-01-25 |
Ligand Pharmaceuticals Incorporated |
Androgen receptor modulator compounds and methods
|
|
WO1998007435A1
(en)
|
1996-08-20 |
1998-02-26 |
The Regents Of The University Of California |
Eye treatments using synthetic thyroid hormone compositions
|
|
NZ334891A
(en)
*
|
1996-10-24 |
2001-04-27 |
Novartis Ag |
Substituted aminoalkane phosphonic acids for treating block excitatory amino acid receptors related diseases
|
|
AU6452098A
(en)
|
1997-03-07 |
1998-09-22 |
Metabasis Therapeutics, Inc. |
Novel purine inhibitors of fructose-1,6-bisphosphatase
|
|
ATE253073T1
(de)
|
1997-03-07 |
2003-11-15 |
Metabasis Therapeutics Inc |
Neue benzimidazol inhibitoren der fructose-1,6- bisphosphatase
|
|
AU6691798A
(en)
|
1997-03-07 |
1998-09-22 |
Metabasis Therapeutics, Inc. |
Novel indole and azaindole inhibitors of fructose-1,6-bisphosphatase
|
|
JP2001514667A
(ja)
|
1997-03-17 |
2001-09-11 |
タム,ユン ケー. |
肝臓脂肪症の予防のための組成物
|
|
US5951989A
(en)
*
|
1997-04-07 |
1999-09-14 |
Heymann; Warren R. |
Method for the treatment of dry skin
|
|
NZ501156A
(en)
|
1997-05-26 |
2002-02-01 |
Kowa Co |
Azole compounds having a cyclic diamine structure and their use in treating high cholesterol related diseases
|
|
US6423754B1
(en)
|
1997-06-18 |
2002-07-23 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with polyallylamine polymers
|
|
US5883294A
(en)
*
|
1997-06-18 |
1999-03-16 |
The Regeants Of The University Of California |
Selective thyroid hormone analogs
|
|
GB9713739D0
(en)
*
|
1997-06-27 |
1997-09-03 |
Karobio Ab |
Thyroid receptor ligands
|
|
MY125849A
(en)
|
1997-07-25 |
2006-08-30 |
Alza Corp |
Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
|
|
CA2296358A1
(en)
|
1997-09-05 |
1999-03-18 |
Jeremy John Edmunds |
Certain benzothiazine dioxide endothelin antagonists and processes for their preparation
|
|
US5922775A
(en)
*
|
1997-10-23 |
1999-07-13 |
Octamer, Inc. |
Method of treating malignant tumors with ketone thyroxine analogues having no significant hormonal activity
|
|
BR9813508A
(pt)
|
1997-12-11 |
2000-10-03 |
Univ Oxford |
Inibição de replicação viral associada com membrana
|
|
JP4215188B2
(ja)
|
1997-12-22 |
2009-01-28 |
インターシア セラピューティクス,インコーポレイティド |
薬剤供給を調節するデバイスのための速度調節膜
|
|
ES2217613T3
(es)
|
1997-12-29 |
2004-11-01 |
Alza Corporation |
Sistema de liberacion osmotica con mecanismo de retencion de tapon de membrana.
|
|
DE69834213T2
(de)
|
1997-12-31 |
2007-01-25 |
Alza Corp., Mountain View |
Osmotisches Abgabesystem für ein nützliches Mittel
|
|
EP1054588A4
(en)
|
1998-02-03 |
2002-09-25 |
Univ Maryland |
METHOD FOR STIMULATING THE PRODUCTION OF SPERM AND THE DEVELOPMENT OF OVARIES IN ANIMALS
|
|
US6245357B1
(en)
|
1998-03-06 |
2001-06-12 |
Alza Corporation |
Extended release dosage form
|
|
EP1070084A4
(en)
|
1998-03-16 |
2001-09-12 |
Ontogen Corp |
PIPERAZINE AS INHIBITORS OF FRUKTOSE-1,6-BISPHOSPHATASE (FBPASE)
|
|
US6365185B1
(en)
|
1998-03-26 |
2002-04-02 |
University Of Cincinnati |
Self-destructing, controlled release peroral drug delivery system
|
|
EP1083891B1
(en)
*
|
1998-06-02 |
2003-03-12 |
Arthromics PLC |
Compounds which interact with the thyroid hormone receptor for the treatment of fibrotic disease
|
|
MA26634A1
(fr)
|
1998-06-04 |
2004-12-20 |
Astra Ab |
Nouveaux derives de l'acide 3-aryl propionique et analogues
|
|
SE9801992D0
(sv)
|
1998-06-04 |
1998-06-04 |
Astra Ab |
New 3-aryl-2-hydroxypropionic acid derivative I
|
|
US6221897B1
(en)
|
1998-06-10 |
2001-04-24 |
Aventis Pharma Deutschland Gmbh |
Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
|
|
PA8471201A1
(es)
|
1998-06-16 |
2000-09-29 |
Pfizer Prod Inc |
Combinaciones terapeuticas que comprenden un modulador del receptor de estrogenos selectivo y hormona paratiroidea
|
|
ATE293595T1
(de)
|
1998-06-30 |
2005-05-15 |
Univ California |
Thyroidhormon-analoga und verfahren zu ihrer herstellung
|
|
GB9816935D0
(en)
*
|
1998-08-05 |
1998-09-30 |
Karobio Ab |
Novel glucocortoid and thyroid receptor ligands for the treatment of metabolic disorders
|
|
PL205184B1
(pl)
|
1998-09-09 |
2010-03-31 |
Metabasis Therapeutics Inc |
Nowe heteroaromatyczne inhibitory 1,6-bisfosfatazy fruktozy, kompozycje farmaceutyczne zawierające te związki i ich zastosowanie
|
|
DE19845405C2
(de)
|
1998-10-02 |
2000-07-13 |
Aventis Pharma Gmbh |
Arylsubstituierte Propanolaminderivate und deren Verwendung
|
|
HUP0104993A3
(en)
|
1998-11-02 |
2003-02-28 |
Alza Corp Mountain View |
Method and device for controlled delivery of active agents
|
|
US6342249B1
(en)
|
1998-12-23 |
2002-01-29 |
Alza Corporation |
Controlled release liquid active agent formulation dosage forms
|
|
GB9828442D0
(en)
|
1998-12-24 |
1999-02-17 |
Karobio Ab |
Novel thyroid receptor ligands and method II
|
|
DE60009871T2
(de)
*
|
1999-02-23 |
2005-03-17 |
Ono Pharmaceutical Co. Ltd. |
Medikamente, die derivate der phosphorigensäure als aktiven inhaltsstoff enthalten
|
|
US6344481B1
(en)
*
|
1999-03-01 |
2002-02-05 |
Pfizer Inc. |
Thyromimetic antiobesity agents
|
|
DE60018225T2
(de)
*
|
1999-03-01 |
2005-12-29 |
Pfizer Products Inc., Groton |
Oxamsäuren mit einer Cyanogruppe als Liganden für den Thyroidrezeptor
|
|
IL144765A0
(en)
*
|
1999-03-01 |
2002-06-30 |
Pfizer Prod Inc |
Oxamic acids and derivatives as thyroid receptor ligands
|
|
US6790978B2
(en)
*
|
1999-03-29 |
2004-09-14 |
Novartis Ag |
Thyromimetic organic compounds
|
|
CO5160290A1
(es)
*
|
1999-03-29 |
2002-05-30 |
Novartis Ag |
Derivados de acido fenoxifeniloxamico sustituido .
|
|
US6599942B1
(en)
*
|
1999-03-29 |
2003-07-29 |
Novartis Ag |
Thyromimetic organic compounds
|
|
DE19916108C1
(de)
|
1999-04-09 |
2001-01-11 |
Aventis Pharma Gmbh |
Mit Zuckerresten substituierte 1,4-Benzothiazepin-1,1-dioxidderivate, Verfahren zu deren Herstellung und deren Verwendung
|
|
EE200100558A
(et)
|
1999-04-28 |
2002-12-16 |
Aventis Pharma Deutschland Gmbh |
Triarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi raviotstarbeline kasutamine
|
|
EE200100556A
(et)
|
1999-04-28 |
2003-02-17 |
Aventis Pharma Deutschland Gmbh |
Diarüülhappe derivaat, seda sisaldav farmatseutiline kompositsioon ja ühendi kasutamine ravimite valmistamiseks
|
|
US6776984B1
(en)
|
1999-08-20 |
2004-08-17 |
George R. Schwartz |
Induced regeneration and repair of damaged neurons and nerve axon myelin
|
|
US6348482B1
(en)
*
|
1999-05-05 |
2002-02-19 |
Merck & Co., Inc. |
Catechols as antimicrobial agents
|
|
WO2001010384A2
(en)
*
|
1999-08-10 |
2001-02-15 |
Joslin Diabetes Center, Inc. |
Method for identifying compounds for treatment of insulin resistance
|
|
CZ2002711A3
(cs)
|
1999-08-27 |
2003-11-12 |
Ligand Pharmaceuticals Incorporated |
Modulátory androgenních receptorů, způsoby jejich výroby a způsoby jejich použití
|
|
US6566372B1
(en)
*
|
1999-08-27 |
2003-05-20 |
Ligand Pharmaceuticals Incorporated |
Bicyclic androgen and progesterone receptor modulator compounds and methods
|
|
AU6941200A
(en)
|
1999-08-27 |
2001-03-26 |
Ligand Pharmaceuticals Incorporated |
8-substituted-6-trifluoromethyl-9-pyrido(3,2-g)quinoline compounds as androgen receptor modulators
|
|
US6752981B1
(en)
|
1999-09-08 |
2004-06-22 |
Metabasis Therapeutics, Inc. |
Prodrugs for liver specific drug delivery
|
|
US6414002B1
(en)
*
|
1999-09-22 |
2002-07-02 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
|
TW200514783A
(en)
|
1999-09-22 |
2005-05-01 |
Bristol Myers Squibb Co |
Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method
|
|
US6787652B1
(en)
*
|
1999-09-30 |
2004-09-07 |
Pfizer, Inc. |
6-Azauracil derivatives as thyroid receptor ligands
|
|
US6627660B1
(en)
*
|
1999-11-16 |
2003-09-30 |
New River Pharmaceuticals Inc. |
Stabilized thyroxine compounds
|
|
GB9927056D0
(en)
|
1999-11-17 |
2000-01-12 |
Karobio Ab |
Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders
|
|
SE9904413D0
(sv)
|
1999-12-03 |
1999-12-03 |
Astra Ab |
Comminuted form
|
|
AU773777B2
(en)
|
1999-12-03 |
2004-06-03 |
Astrazeneca Ab |
Crystalline form of (S)-2 ethoxy-3-(4-(2-(4-methanesulfonyloxyphenyl) ethoxy) phenyl) propanoic acid
|
|
EP1127882A1
(en)
*
|
2000-01-25 |
2001-08-29 |
Pfizer Products Inc. |
Tetrazole compounds as thyroid receptor ligands
|
|
AU2001230929B2
(en)
|
2000-02-17 |
2004-09-23 |
Bristol-Myers Squibb Co. |
Aniline-derived ligands for the thyroid receptor
|
|
US6852706B1
(en)
*
|
2000-03-22 |
2005-02-08 |
The Wistar Institute |
Methods and compositions for healing heart wounds
|
|
US6664291B2
(en)
*
|
2000-03-31 |
2003-12-16 |
Pfizer, Inc. |
Malonamic acids and derivatives thereof as thyroid receptor ligands
|
|
TR200202249T2
(tr)
|
2000-03-31 |
2003-01-21 |
Pfizer Products Inc. |
Tiroit reseptörü ligantları olarak malonik asitler ve bunların türevleri
|
|
CA2405548A1
(en)
|
2000-04-17 |
2001-10-25 |
Sa Majeste La Reine Du Chef Du Canada Agriculture Et Agroalimentaire Canada |
Steatosis-modulating factors and uses thereof
|
|
US6620830B2
(en)
*
|
2000-04-21 |
2003-09-16 |
Pfizer, Inc. |
Thyroid receptor ligands
|
|
WO2001081327A1
(en)
|
2000-04-25 |
2001-11-01 |
Kyorin Pharmaceutical Co., Ltd. |
Novel stable crystal of thiazolidinedione derivative and process for producing the same
|
|
US6395784B1
(en)
|
2000-06-07 |
2002-05-28 |
Bristol-Myers Squibb Company |
Benzamide ligands for the thyroid receptor
|
|
GB0015205D0
(en)
|
2000-06-21 |
2000-08-09 |
Karobio Ab |
Bioisosteric thyroid receptor ligands and method
|
|
CA2413417A1
(en)
|
2000-06-28 |
2002-01-03 |
Bristol-Myers Squibb Company |
Selective androgen receptor modulators and methods for their identification, design and use
|
|
US20020077364A1
(en)
|
2000-07-06 |
2002-06-20 |
Ramaswamy Murari |
Thyroid hormone formulations
|
|
AU2001269307A1
(en)
|
2000-07-10 |
2002-01-21 |
Btg International Limited |
Insulin derivatives and synthesis thereof
|
|
EP1749539A2
(en)
*
|
2000-08-01 |
2007-02-07 |
Shionogi Co., Ltd. |
Preventives or remedies for fatty liver
|
|
IL137672A0
(en)
|
2000-08-03 |
2001-10-31 |
Dpharm Ltd |
Derivatives of branched-chain lipophilic molecules and uses thereof
|
|
DE10038007A1
(de)
*
|
2000-08-04 |
2002-02-14 |
Bayer Ag |
Neue Amino-und Amido-Diphenylether für Arzneimittel
|
|
WO2002015845A2
(en)
*
|
2000-08-21 |
2002-02-28 |
Merck & Co., Inc. |
Anti-hypercholesterolemic drug combination
|
|
CA2420279C
(en)
|
2000-08-24 |
2011-07-19 |
The University Of Tennessee Research Corporation |
Selective androgen receptor modulators and methods of use thereof
|
|
DE10046029A1
(de)
*
|
2000-09-18 |
2002-03-28 |
Bayer Ag |
Indazole
|
|
AU9479201A
(en)
|
2000-09-27 |
2002-04-08 |
Ilex Oncology Res S A |
Alpha-substituted beta-aminoethyl phosphonates
|
|
WO2002032408A2
(en)
|
2000-10-20 |
2002-04-25 |
Novartis Ag |
Combinations of a thyromimetic compound and a statin
|
|
HRP20030498A2
(en)
|
2000-12-21 |
2005-04-30 |
Aventis Pharma Deutschland Gmbh |
Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
|
|
JP2004517851A
(ja)
*
|
2000-12-27 |
2004-06-17 |
バイエル アクチェンゲゼルシャフト |
甲状腺受容体のリガンドとしてのインドール誘導体
|
|
US6982348B2
(en)
*
|
2001-01-26 |
2006-01-03 |
Takeda Pharmaceutical Company Limited |
Aminoethanol derivatives
|
|
WO2002060374A2
(en)
|
2001-01-29 |
2002-08-08 |
Insight Strategy And Marketing Ltd |
Benz-1,3-azole derivatives and their uses as heparanase inhibitors
|
|
US6534676B2
(en)
*
|
2001-01-31 |
2003-03-18 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Method to treat chronic heart failure and/or elevated cholesterol levels using 3,5-diiodothyropropionic acid and method to prepare same
|
|
US6716877B2
(en)
*
|
2001-01-31 |
2004-04-06 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Method to treat chronic heart failure and/or elevated cholesterol levels
|
|
KR20030072396A
(ko)
|
2001-02-08 |
2003-09-13 |
카로 바이오 아베 |
갑상선 수용체 리간드
|
|
WO2002066017A1
(en)
|
2001-02-20 |
2002-08-29 |
Abbott Laboratories |
Liothyronine sodium and levothyroxine sodium combination
|
|
MXPA03008229A
(es)
|
2001-03-14 |
2004-11-12 |
Lilly Co Eli |
Trienos fluorados y su uso como moduladores rxr.
|
|
DE10115408A1
(de)
*
|
2001-03-29 |
2002-10-02 |
Bayer Ag |
Benzofuran-Derivate
|
|
US6825201B2
(en)
*
|
2001-04-25 |
2004-11-30 |
Bristol-Myers Squibb Company |
Indole, azaindole and related heterocyclic amidopiperazine derivatives
|
|
GB0111861D0
(en)
*
|
2001-05-15 |
2001-07-04 |
Karobio Ab |
Novel compounds
|
|
FR2825926A1
(fr)
*
|
2001-06-14 |
2002-12-20 |
Sod Conseils Rech Applic |
Derives d'imidazoles modulant les canaux sodiques
|
|
US20030022868A1
(en)
|
2001-06-25 |
2003-01-30 |
Dalton James T. |
Selective androgen receptor modulators and methods of use thereof
|
|
WO2003003013A1
(en)
|
2001-06-29 |
2003-01-09 |
University Of Massachusetts |
Non-nuclear effects of thyroid hormone
|
|
US6645974B2
(en)
|
2001-07-31 |
2003-11-11 |
Merck & Co., Inc. |
Androgen receptor modulators and methods for use thereof
|
|
EP1414795A4
(en)
|
2001-07-31 |
2006-03-01 |
Bristol Myers Squibb Co |
BICYCLIC MODULATORS OF THE FUNCTION OF THE ANDROGEN RECEPTOR
|
|
EP1285914B1
(en)
|
2001-08-13 |
2007-12-19 |
PheneX Pharmaceuticals AG |
Nr1h4 nuclear receptor binding compounds
|
|
WO2003061557A2
(en)
|
2001-08-14 |
2003-07-31 |
King Pharmaceuticals, Inc. |
Levothyroxine pharmaceutical compositions, methods of making and methods of administration
|
|
JP2005507381A
(ja)
|
2001-08-24 |
2005-03-17 |
カロ バイオ アクチェブラーグ |
心臓障害および代謝障害の治療のための主要環置換甲状腺受容体アンタゴニスト
|
|
UA76773C2
(uk)
|
2001-08-31 |
2006-09-15 |
Санофі-Авентіс Дойчланд Гмбх |
Діарилциклоалкільні похідні, спосіб їх одержання і їх застосування як ppar-активаторів
|
|
DE60208132T2
(de)
*
|
2001-09-26 |
2006-07-20 |
Pfizer Products Inc., Groton |
Indolcaroboxylsäure als Thyroidrezeptor-Liganden
|
|
US6806381B2
(en)
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
|
US6673815B2
(en)
*
|
2001-11-06 |
2004-01-06 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
|
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
CA2472680A1
(en)
|
2002-01-18 |
2003-07-31 |
Merck & Co., Inc. |
Selective s1p1/edg1 receptor agonists
|
|
EP1471049A4
(en)
|
2002-01-30 |
2006-08-16 |
Kissei Pharmaceutical |
NEW THYROIDIAN HORMONE RECEPTOR LIGAND, MEDICINAL PREPARATIONS CONTAINING THE SAME AND USE THEREOF
|
|
WO2003070169A2
(en)
|
2002-02-19 |
2003-08-28 |
Ilex Products, Inc. |
Aminodiphosphonate apolipoprotein e modulators
|
|
EP1490084A4
(en)
|
2002-03-04 |
2006-06-07 |
Smithkline Beecham Corp |
COMPOSITIONS AND METHODS OF REGULATING THE THYROID SYRINGE AND CHOLESTEROL AND LIPID METABOLIC CHANGES VIA THE NUCLEAR RECEPTOR CAR
|
|
ATE377644T1
(de)
*
|
2002-03-25 |
2007-11-15 |
Applera Corp |
Systeme und verfahren zum nachweis der funktion nukleärer rezeptoren unter verwendung von reporterenzymmutanten komplementierungen
|
|
GB0208384D0
(en)
|
2002-04-11 |
2002-05-22 |
Karobio Ab |
Novel compounds
|
|
AU2003225305A1
(en)
|
2002-05-08 |
2003-11-11 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
|
EP1364962A1
(en)
|
2002-05-24 |
2003-11-26 |
Stichting tot bevordering van de wetenschap der Endocrinologie |
Use of monocarboxylate transporter proteins for thyroid hormone transport
|
|
AU2003248676A1
(en)
|
2002-06-15 |
2003-12-31 |
Enteromed, Inc. |
Treatment of non-alcoholic fatty liver disease
|
|
US20040137441A1
(en)
|
2003-01-15 |
2004-07-15 |
Isis Pharmaceuticals Inc. |
Modulation of thyroid hormone receptor interactor 3 expression
|
|
GEP20084475B
(en)
*
|
2002-07-09 |
2008-09-10 |
Bristol Myers Squibb Co |
Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method for their production
|
|
GB0215978D0
(en)
|
2002-07-10 |
2002-08-21 |
Karobio Ab |
Novel compounds
|
|
WO2004014318A2
(en)
|
2002-08-10 |
2004-02-19 |
King Pharmaceuticals, Inc. |
Levothyroxine compositions and methods
|
|
GB0219022D0
(en)
|
2002-08-15 |
2002-09-25 |
Karobio Ab |
Novel thyromimetic compounds
|
|
WO2004026097A2
(en)
|
2002-09-19 |
2004-04-01 |
First Circle Medical, Inc. |
Treatment of steatosis using hyperthermia
|
|
HRP20050053A2
(en)
*
|
2002-09-19 |
2005-04-30 |
Solvay Pharmaceuticals B.V. |
1 h-1,2,4-triazole-3-carboxamide derivatives as cannabinoid-cb1 receptor ligands
|
|
EP1565171A4
(en)
|
2002-11-05 |
2010-06-30 |
Shire Llc |
PROGRESSIVE ABSORPTION OF MIXED FORMULATIONS OF THYROID HORMONES
|
|
ITMI20022777A1
(it)
*
|
2002-12-27 |
2004-06-28 |
Altergon Sa |
Formulazioni farmaceutiche per ormoni tiroidei e procedimenti per il loro ottenimento.
|
|
US20040142868A1
(en)
*
|
2003-01-21 |
2004-07-22 |
Sleeman Mark W. |
Method of treating liver steatosis in a mammal
|
|
TW200504021A
(en)
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
US20040176425A1
(en)
|
2003-01-24 |
2004-09-09 |
Washburn William N. |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
|
CA2517896A1
(en)
|
2003-03-05 |
2004-09-16 |
Zymogenetics, Inc. |
Use of thyroid-stimulating hormone to induce lipolysis
|
|
AU2003901813A0
(en)
|
2003-04-15 |
2003-05-01 |
Vital Health Sciences Pty Ltd |
Pharmaceutical derivatives
|
|
US7557143B2
(en)
*
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
WO2004103289A2
(en)
|
2003-05-14 |
2004-12-02 |
New York University |
Driverse thyroid hormone receptor antagonists and uses thereof
|
|
ITRM20030363A1
(it)
|
2003-07-24 |
2005-01-25 |
Fernando Goglia |
Composizioni comprendenti la 3, 5diiodotironina e uso farmaceutico di esse.
|
|
WO2005016862A1
(en)
|
2003-08-14 |
2005-02-24 |
Asahi Kasei Pharma Corporation |
Substituted arylalkanoic acid derivative and use thereof
|
|
US6952844B2
(en)
|
2003-08-27 |
2005-10-11 |
Danaher Thomas C |
Bed-tent
|
|
WO2005028488A1
(en)
|
2003-09-12 |
2005-03-31 |
Quatrx Pharmaceuticals Co. |
Heteroaryl phosphinyl and thiophosphinyl compounds for regulation of glucose, triglycerides, and ldl/hdl levels
|
|
EP2335694B1
(en)
|
2003-09-15 |
2018-06-13 |
NanoPharmaceuticals LLC |
Thyroid hormone analogs and methods of use
|
|
WO2005030198A1
(ja)
|
2003-09-26 |
2005-04-07 |
Chugai Seiyaku Kabushiki Kaisha |
脂肪肝又は肝疾患を治療するための医薬組成物
|
|
WO2005042556A1
(en)
|
2003-10-27 |
2005-05-12 |
Genelabs Technologies, Inc. |
Nucleoside compounds for treating viral infections
|
|
JP2007512359A
(ja)
*
|
2003-11-19 |
2007-05-17 |
メタバシス・セラピューティクス・インコーポレイテッド |
新規なリン含有甲状腺ホルモン様物質
|
|
WO2006128055A2
(en)
|
2005-05-26 |
2006-11-30 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
AU2005254940A1
(en)
|
2004-06-08 |
2005-12-29 |
Metabasis Therapeutics, Inc. |
Lewis acid mediated synthesis of cyclic esters
|
|
RU2007148927A
(ru)
|
2005-05-26 |
2009-07-10 |
Метабэйзис Терапьютикс, Инк. (Us) |
Новые тиреомиметики, содержащие фосфиновую кислоту
|
|
CA2606499C
(en)
|
2005-05-26 |
2017-06-13 |
Metabasis Therapeutics, Inc. |
Thyromimetics for the treatment of fatty liver diseases
|
|
CA2614529C
(en)
|
2005-07-21 |
2011-06-28 |
F. Hoffmann-La Roche Ag |
Pyridazinone derivatives as thyroid hormone receptor agonists
|