JP2005526011A5 - - Google Patents
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- Publication number
- JP2005526011A5 JP2005526011A5 JP2003552709A JP2003552709A JP2005526011A5 JP 2005526011 A5 JP2005526011 A5 JP 2005526011A5 JP 2003552709 A JP2003552709 A JP 2003552709A JP 2003552709 A JP2003552709 A JP 2003552709A JP 2005526011 A5 JP2005526011 A5 JP 2005526011A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- formula
- acceptable salt
- oxoethoxy
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000003839 salts Chemical group 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000012453 solvate Chemical group 0.000 claims 4
- 239000013078 crystal Chemical group 0.000 claims 3
- IWPXYUBPRFHKJQ-DEOSSOPVSA-N (2s)-3-[4-[2-[benzyl(hexyl)amino]-2-oxoethoxy]phenyl]-2-ethoxypropanoic acid Chemical compound C=1C=C(C[C@H](OCC)C(O)=O)C=CC=1OCC(=O)N(CCCCCC)CC1=CC=CC=C1 IWPXYUBPRFHKJQ-DEOSSOPVSA-N 0.000 claims 2
- -1 alkanoyloxymethyl ester Chemical class 0.000 claims 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 125000006239 protecting group Chemical group 0.000 claims 2
- VFYAWARECOZRBD-VWLOTQADSA-N (2s)-2-ethoxy-3-[4-[2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy]phenyl]propanoic acid Chemical compound C=1C=C(C[C@H](OCC)C(O)=O)C=CC=1OCC(=O)N(CCCCCC)CCC1=CC=CC=C1 VFYAWARECOZRBD-VWLOTQADSA-N 0.000 claims 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 125000004849 alkoxymethyl group Chemical group 0.000 claims 1
- 125000005907 alkyl ester group Chemical group 0.000 claims 1
- 239000012351 deprotecting agent Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 235000019260 propionic acid Nutrition 0.000 claims 1
- 0 *c1ccccc1 Chemical compound *c1ccccc1 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0104334A SE0104334D0 (sv) | 2001-12-19 | 2001-12-19 | Therapeutic agents |
| PCT/GB2002/005738 WO2003051821A1 (en) | 2001-12-19 | 2002-12-18 | Substituted phenylpropionic acid derivatives as agonists to human peroxisome proliferator-activated receptor alpha (ppar) |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005235794A Division JP2005336209A (ja) | 2001-12-19 | 2005-08-16 | ヒトのペルオキシソーム増殖因子活性化受容体α（ＰＰＡＲ）に対するアゴニストとしての置換フェニルプロピオン酸誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005526011A JP2005526011A (ja) | 2005-09-02 |
| JP2005526011A5 true JP2005526011A5 (enExample) | 2006-01-05 |
| JP3784804B2 JP3784804B2 (ja) | 2006-06-14 |
Family
ID=20286433
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003552710A Expired - Lifetime JP3820249B2 (ja) | 2001-12-19 | 2002-12-18 | ヒトペルオキソーム増殖因子活性化受容体α（ＰＰＡＲ）のアゴニストである置換フェニルプロピオン酸誘導体 |
| JP2003552709A Expired - Fee Related JP3784804B2 (ja) | 2001-12-19 | 2002-12-18 | ヒトのペルオキシソーム増殖因子活性化受容体α（ＰＰＡＲ）に対するアゴニストとしての置換フェニルプロピオン酸誘導体 |
| JP2005235794A Pending JP2005336209A (ja) | 2001-12-19 | 2005-08-16 | ヒトのペルオキシソーム増殖因子活性化受容体α（ＰＰＡＲ）に対するアゴニストとしての置換フェニルプロピオン酸誘導体 |
| JP2006123399A Pending JP2006298924A (ja) | 2001-12-19 | 2006-04-27 | 置換フェニルプロピオン酸誘導体を含む医薬組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003552710A Expired - Lifetime JP3820249B2 (ja) | 2001-12-19 | 2002-12-18 | ヒトペルオキソーム増殖因子活性化受容体α（ＰＰＡＲ）のアゴニストである置換フェニルプロピオン酸誘導体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005235794A Pending JP2005336209A (ja) | 2001-12-19 | 2005-08-16 | ヒトのペルオキシソーム増殖因子活性化受容体α（ＰＰＡＲ）に対するアゴニストとしての置換フェニルプロピオン酸誘導体 |
| JP2006123399A Pending JP2006298924A (ja) | 2001-12-19 | 2006-04-27 | 置換フェニルプロピオン酸誘導体を含む医薬組成物 |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US7256307B2 (enExample) |
| EP (2) | EP1458673B1 (enExample) |
| JP (4) | JP3820249B2 (enExample) |
| KR (2) | KR20040074094A (enExample) |
| CN (3) | CN1620423A (enExample) |
| AR (2) | AR038047A1 (enExample) |
| AT (2) | ATE363466T1 (enExample) |
| AU (2) | AU2002366315A1 (enExample) |
| BR (2) | BR0214988A (enExample) |
| CA (2) | CA2469302A1 (enExample) |
| CY (2) | CY1106276T1 (enExample) |
| DE (2) | DE60214594T2 (enExample) |
| DK (2) | DK1458673T3 (enExample) |
| ES (2) | ES2286310T3 (enExample) |
| HU (2) | HUP0402022A3 (enExample) |
| IL (3) | IL162330A0 (enExample) |
| IS (2) | IS7309A (enExample) |
| MX (2) | MXPA04006004A (enExample) |
| MY (1) | MY132565A (enExample) |
| NO (2) | NO20043023L (enExample) |
| NZ (2) | NZ533276A (enExample) |
| PL (2) | PL370673A1 (enExample) |
| PT (2) | PT1458672E (enExample) |
| RU (2) | RU2300517C2 (enExample) |
| SE (1) | SE0104334D0 (enExample) |
| SI (2) | SI1458672T1 (enExample) |
| TW (2) | TWI255807B (enExample) |
| UA (2) | UA77460C2 (enExample) |
| WO (2) | WO2003051821A1 (enExample) |
| ZA (2) | ZA200404657B (enExample) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2232434T3 (es) | 1999-03-05 | 2005-06-01 | Duke University | Analogos de prostaglandinas c-16 fp selectivas insaturadas. |
| US20020013294A1 (en) | 2000-03-31 | 2002-01-31 | Delong Mitchell Anthony | Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives |
| US20020172693A1 (en) | 2000-03-31 | 2002-11-21 | Delong Michell Anthony | Compositions and methods for treating hair loss using non-naturally occurring prostaglandins |
| SE0104333D0 (sv) | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| GB0229931D0 (en) * | 2002-12-21 | 2003-01-29 | Astrazeneca Ab | Therapeutic agents |
| GB0314079D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| SE0104334D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
| GB0209467D0 (en) * | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
| AU2003241579B9 (en) | 2002-06-19 | 2009-07-30 | Eli Lilly And Company | Amide linker peroxisome proliferator activated receptor modulators |
| CA2489834C (en) | 2002-06-20 | 2006-10-03 | Astrazeneca Ab | Ortho-substituted benzoic acid derivatives for the treatment of insulin resistance |
| FR2848452B1 (fr) * | 2002-12-12 | 2007-04-06 | Aventis Pharma Sa | Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer |
| DE602004009295T2 (de) | 2003-01-14 | 2008-07-03 | Arena Pharmaceuticals, Inc., San Diego | 1,2,3-trisubstituierte aryl- und heteroarylderivate als modulatoren des metabolismus zur vorbeugung und behandlung von metabolismus-bedingten krankheiten wie diabetes oder hyperglykämie |
| GB0304194D0 (en) * | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
| GB0314136D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314129D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314134D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| EP2292620A3 (en) | 2003-07-14 | 2011-06-22 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prohylaxis and treatment of disorders related thereto |
| WO2005053683A1 (en) * | 2003-11-26 | 2005-06-16 | Duke University | A method of preventing or treating glaucoma |
| CN1886364A (zh) * | 2003-12-15 | 2006-12-27 | 伊莱利利公司 | 选择性过氧化物酶体增殖物激活受体调节剂 |
| BRPI0515015A (pt) | 2004-08-11 | 2008-07-01 | Kyorin Seiyaku Kk | derivado cìclico de ácido aminobenzóico; medicamento; agonista ppar(alpha); agonista duplo ppar(alpha), y; agonista duplo ppar(alpha), (delta); modulador ppar; agente lipìdeo; agente profilático ou terapêutico compreendendo pelo menos um dos derivados cìclicos de ácido aminobenzóico ou sal do mesmo farmacêuticamente aceitável |
| SE0403072D0 (sv) * | 2004-12-16 | 2004-12-16 | Astrazeneca Ab | Pharmaceutically useful salts of carboxylic acid derivates |
| EP1893583B1 (en) | 2005-05-31 | 2012-04-04 | Pfizer Inc. | Substituted aryloxy-n-bicyclomethyl acetamide compounds as vr1 antagonists |
| WO2007004957A1 (en) * | 2005-07-05 | 2007-01-11 | Astrazeneca Ab | Novel crystalline form |
| AR055073A1 (es) * | 2005-07-11 | 2007-08-01 | Astrazeneca Ab | Agentes terapeuticos |
| TWI331523B (en) * | 2005-12-08 | 2010-10-11 | Nat Health Research Institutes | Vinylsulfonate compounds |
| CN101054372B (zh) * | 2006-04-11 | 2010-10-13 | 中国科学院上海药物研究所 | 嘧啶取代苯丙酸衍生化合物、其制法和在治疗多囊肾疾病中的用途 |
| KR100847780B1 (ko) * | 2006-10-26 | 2008-07-23 | 재단법인서울대학교산학협력재단 | 2-에톡시프로피온산 유도체 또는 이의 약학적으로허용가능한 염, 이의 제조방법 및 이를 유효성분으로함유하는 당뇨병 예방 및 치료제 |
| RU2361581C2 (ru) | 2007-09-14 | 2009-07-20 | Закрытое Акционерное Общество "Мастерклон" | Фармацевтическая композиция, обладающая противодиабетической, гиполипидемической, гипогликемической и гипохолестеринемической активностью, способ ее получения и способы лечения указанных заболеваний |
| US20110293549A1 (en) | 2009-02-03 | 2011-12-01 | Athena Cosmetics, Inc. | Composition, method and kit for enhancing hair |
| PH12013500547A1 (en) | 2010-09-22 | 2013-06-10 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| LT3400944T (lt) | 2010-11-04 | 2020-09-25 | Albireo Ab | Ibat inhibitoriai, skirt kepenų ligų gydymui |
| JO3301B1 (ar) * | 2013-04-26 | 2018-09-16 | Albireo Ab | تعديلات بلورية على إيلوبيكسيبات |
| KR102560954B1 (ko) | 2014-06-25 | 2023-07-31 | 이에이 파마 가부시키가이샤 | 고형 제제 및 그의 착색 방지 또는 착색 감소 방법 |
| EP3012252A1 (en) | 2014-10-24 | 2016-04-27 | Ferring BV | Crystal modifications of elobixibat |
| ES2995737T3 (en) | 2015-01-06 | 2025-02-11 | Arena Pharm Inc | Compound for use in treating conditions related to the s1p1 receptor |
| MA42807A (fr) | 2015-06-22 | 2018-07-25 | Arena Pharm Inc | Sel l-arginine cristallin d'acide (r)-2-(7-(4-cyclopentyl-3-(trifluorométhyl)benzyloxy)-1,2,3,4-tétrahydrocyclo-penta[b]indol-3-yl)acétique (composé 1) pour une utilisation dans des troubles associés au récepteur de s1p1 |
| US10441605B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
| US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| WO2018151873A1 (en) | 2017-02-16 | 2018-08-23 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of primary biliary cholangitis |
| JP2020530448A (ja) | 2017-08-09 | 2020-10-22 | アルビレオ・アクチボラグ | コレスチラミン顆粒、経口コレスチラミン製剤、及びそれらの使用 |
| US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| ES2942443T3 (es) | 2018-06-05 | 2023-06-01 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores de ácidos biliares |
| EP3801459B1 (en) | 2018-06-06 | 2024-08-07 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the s1p1 receptor |
| US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
| PE20210136A1 (es) | 2018-06-20 | 2021-01-21 | Albireo Ab | Formulacion farmaceutica de odevixibat |
| US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US11549878B2 (en) | 2018-08-09 | 2023-01-10 | Albireo Ab | In vitro method for determining the adsorbing capacity of an insoluble adsorbant |
| US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
| US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
| US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
| SMT202300020T1 (it) | 2019-02-06 | 2023-03-17 | Albireo Ab | Composti di benzotiadiazepine e loro uso come modulatori degli acidi biliari |
| EP4069361B1 (en) | 2019-12-04 | 2024-01-03 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
| ES2972045T3 (es) | 2019-12-04 | 2024-06-10 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar |
| JP7665620B2 (ja) | 2019-12-04 | 2025-04-21 | アルビレオ・アクチボラグ | ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
| US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
| ES2973549T3 (es) | 2019-12-04 | 2024-06-20 | Albireo Ab | Compuestos de benzoti(di)azepina y su uso como moduladores de los ácidos biliares |
| ES3002777T3 (en) | 2020-08-03 | 2025-03-07 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| KR20230106651A (ko) | 2020-11-12 | 2023-07-13 | 알비레오 에이비 | 진행성 가족성 간내 담즙정체증(pfic)을 치료하기 위한 오데빅시바트 |
| CA3198216A1 (en) | 2020-12-04 | 2022-06-09 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
| TW202313579A (zh) | 2021-06-03 | 2023-04-01 | 瑞典商艾爾比瑞歐公司 | 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途 |
| WO2023039276A1 (en) * | 2021-09-13 | 2023-03-16 | Curtails Llc | Use of ibat inhibitors and antimicrobials for the treatment of diseases |
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| JP4618845B2 (ja) * | 1999-06-09 | 2011-01-26 | 杏林製薬株式会社 | ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体 |
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| GB0314079D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| AU2003241579B9 (en) * | 2002-06-19 | 2009-07-30 | Eli Lilly And Company | Amide linker peroxisome proliferator activated receptor modulators |
| GB0314134D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314129D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
| GB0314136D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
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2001
- 2001-12-19 SE SE0104334A patent/SE0104334D0/xx unknown
-
2002
- 2002-12-18 RU RU2004116918/04A patent/RU2300517C2/ru not_active IP Right Cessation
- 2002-12-18 CA CA002469302A patent/CA2469302A1/en not_active Abandoned
- 2002-12-18 KR KR10-2004-7009517A patent/KR20040074094A/ko not_active Ceased
- 2002-12-18 EP EP02804964A patent/EP1458673B1/en not_active Expired - Lifetime
- 2002-12-18 PT PT02788145T patent/PT1458672E/pt unknown
- 2002-12-18 DK DK02804964T patent/DK1458673T3/da active
- 2002-12-18 KR KR10-2004-7009501A patent/KR20040074092A/ko not_active Withdrawn
- 2002-12-18 TW TW091136519A patent/TWI255807B/zh not_active IP Right Cessation
- 2002-12-18 TW TW091136518A patent/TWI253444B/zh not_active IP Right Cessation
- 2002-12-18 US US10/499,378 patent/US7256307B2/en not_active Expired - Fee Related
- 2002-12-18 IL IL16233002A patent/IL162330A0/xx unknown
- 2002-12-18 CA CA002470491A patent/CA2470491A1/en not_active Abandoned
- 2002-12-18 HU HU0402022A patent/HUP0402022A3/hu unknown
- 2002-12-18 BR BR0214988-5A patent/BR0214988A/pt not_active IP Right Cessation
- 2002-12-18 NZ NZ533276A patent/NZ533276A/en unknown
- 2002-12-18 DK DK02788145T patent/DK1458672T3/da active
- 2002-12-18 RU RU2004116917/04A patent/RU2303031C2/ru not_active IP Right Cessation
- 2002-12-18 US US10/499,261 patent/US7514471B2/en not_active Expired - Fee Related
- 2002-12-18 ES ES02788145T patent/ES2286310T3/es not_active Expired - Lifetime
- 2002-12-18 AT AT02788145T patent/ATE363466T1/de not_active IP Right Cessation
- 2002-12-18 MX MXPA04006004A patent/MXPA04006004A/es active IP Right Grant
- 2002-12-18 WO PCT/GB2002/005738 patent/WO2003051821A1/en not_active Ceased
- 2002-12-18 CN CNA028281551A patent/CN1620423A/zh active Pending
- 2002-12-18 SI SI200230570T patent/SI1458672T1/sl unknown
- 2002-12-18 WO PCT/GB2002/005744 patent/WO2003051822A1/en not_active Ceased
- 2002-12-18 BR BR0214986-9A patent/BR0214986A/pt not_active IP Right Cessation
- 2002-12-18 ES ES02804964T patent/ES2271381T3/es not_active Expired - Lifetime
- 2002-12-18 JP JP2003552710A patent/JP3820249B2/ja not_active Expired - Lifetime
- 2002-12-18 AU AU2002366315A patent/AU2002366315A1/en not_active Abandoned
- 2002-12-18 SI SI200230424T patent/SI1458673T1/sl unknown
- 2002-12-18 DE DE60214594T patent/DE60214594T2/de not_active Expired - Lifetime
- 2002-12-18 EP EP02788145A patent/EP1458672B1/en not_active Expired - Lifetime
- 2002-12-18 CN CNB2006100071731A patent/CN100406427C/zh not_active Expired - Fee Related
- 2002-12-18 AU AU2002352427A patent/AU2002352427A1/en not_active Abandoned
- 2002-12-18 PL PL02370673A patent/PL370673A1/xx not_active Application Discontinuation
- 2002-12-18 DE DE60220441T patent/DE60220441T2/de not_active Expired - Fee Related
- 2002-12-18 HU HU0402133A patent/HUP0402133A3/hu unknown
- 2002-12-18 CN CNB028281233A patent/CN1293044C/zh not_active Expired - Fee Related
- 2002-12-18 MX MXPA04006003A patent/MXPA04006003A/es active IP Right Grant
- 2002-12-18 NZ NZ533274A patent/NZ533274A/en unknown
- 2002-12-18 UA UA20040604246A patent/UA77460C2/uk unknown
- 2002-12-18 MY MYPI20024740A patent/MY132565A/en unknown
- 2002-12-18 JP JP2003552709A patent/JP3784804B2/ja not_active Expired - Fee Related
- 2002-12-18 PT PT02804964T patent/PT1458673E/pt unknown
- 2002-12-18 UA UA20040604245A patent/UA77987C2/uk unknown
- 2002-12-18 IL IL16233102A patent/IL162331A0/xx unknown
- 2002-12-18 PL PL02370672A patent/PL370672A1/xx not_active Application Discontinuation
- 2002-12-18 AT AT02804964T patent/ATE338743T1/de not_active IP Right Cessation
- 2002-12-19 AR ARP020105004A patent/AR038047A1/es not_active Application Discontinuation
- 2002-12-19 AR ARP020105002A patent/AR038045A1/es unknown
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2004
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- 2004-06-11 ZA ZA200404657A patent/ZA200404657B/en unknown
- 2004-06-11 ZA ZA200404658A patent/ZA200404658B/en unknown
- 2004-06-14 IS IS7309A patent/IS7309A/is unknown
- 2004-06-15 IS IS7313A patent/IS7313A/is unknown
- 2004-07-15 NO NO20043023A patent/NO20043023L/no not_active Application Discontinuation
- 2004-07-16 NO NO20043164A patent/NO20043164L/no not_active Application Discontinuation
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2005
- 2005-08-16 JP JP2005235794A patent/JP2005336209A/ja active Pending
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2006
- 2006-04-27 JP JP2006123399A patent/JP2006298924A/ja active Pending
- 2006-12-05 CY CY20061101743T patent/CY1106276T1/el unknown
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2007
- 2007-08-01 CY CY20071101028T patent/CY1106784T1/el unknown
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