JP2012522840A5 -

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Publication number: JP2012522840A5
Authority: JP; Japan
Prior art keywords: ester; pharmaceutically acceptable; acceptable salt; alkenyl; alkyl ester
Prior art date: 2010-04-06
Legal status : Granted

Application number

JP2012504771A

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Filing date

2010-04-06

Publication date

2013-05-23

2010-04-06 Application filed filed Critical

2010-04-06 Priority claimed from PCT/US2010/030073 external-priority patent/WO2010118006A1/en

2012-09-27 Publication of JP2012522840A publication Critical patent/JP2012522840A/ja

2013-05-23 Publication of JP2012522840A5 publication Critical patent/JP2012522840A5/ja

2015-03-18 Application granted granted Critical

2015-03-18 Publication of JP5687687B2 publication Critical patent/JP5687687B2/ja

Status Active legal-status Critical Current

2030-04-06 Anticipated expiration legal-status Critical

-1 C 2-6 alkenyl ester Chemical class 0.000 claims 22
125000005907 alkyl ester group Chemical group 0.000 claims 21
150000003839 salts Chemical class 0.000 claims 19
150000001875 compounds Chemical class 0.000 claims 13
239000000178 monomer Substances 0.000 claims 1
239000008194 pharmaceutical composition Substances 0.000 claims 1
239000000546 pharmaceutical excipient Substances 0.000 claims 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1
QFCLNANQLDEACT-UHFFFAOYSA-N C(C1)CC11CNCNCC1 Chemical compound C(C1)CC11CNCNCC1 QFCLNANQLDEACT-UHFFFAOYSA-N 0.000 description 1
SNRKAOGJCXPPSV-BWZBUEFSSA-N OC[C@H]([C@H](C1(F)F)O)O[C@H]1N(CC=CCN1)C1=O Chemical compound OC[C@H]([C@H](C1(F)F)O)O[C@H]1N(CC=CCN1)C1=O SNRKAOGJCXPPSV-BWZBUEFSSA-N 0.000 description 1

JP2012504771A 2009-04-06 2010-04-06 癌を治療するための（２’−デオキシ−リボフラノシル）−１，３，４，７−テトラヒドロ−（１，３）ジアゼピン−２−オン誘導体 Active JP5687687B2 (ja)