IL87171A - Andc של מעכב פקטור של רקמת אדם - Google Patents

Andc של מעכב פקטור של רקמת אדם

Info

Publication number
IL87171A
IL87171A IL8717188A IL8717188A IL87171A IL 87171 A IL87171 A IL 87171A IL 8717188 A IL8717188 A IL 8717188A IL 8717188 A IL8717188 A IL 8717188A IL 87171 A IL87171 A IL 87171A
Authority
IL
Israel
Prior art keywords
tfi
cdna
sequence
factor
tissue factor
Prior art date
Application number
IL8717188A
Other languages
English (en)
Other versions
IL87171A0 (en
Original Assignee
Monsanto Co
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22410671&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL87171(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/123,753 external-priority patent/US4966852A/en
Application filed by Monsanto Co, Univ Washington filed Critical Monsanto Co
Publication of IL87171A0 publication Critical patent/IL87171A0/xx
Publication of IL87171A publication Critical patent/IL87171A/he

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL8717188A 1987-11-23 1988-07-21 Andc של מעכב פקטור של רקמת אדם IL87171A (he)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/123,753 US4966852A (en) 1987-07-23 1987-11-23 DNA clone of human tissue factor inhibitor

Publications (2)

Publication Number Publication Date
IL87171A0 IL87171A0 (en) 1988-12-30
IL87171A true IL87171A (he) 1995-08-31

Family

ID=22410671

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8717188A IL87171A (he) 1987-11-23 1988-07-21 Andc של מעכב פקטור של רקמת אדם

Country Status (15)

Country Link
EP (1) EP0318451B1 (he)
JP (5) JP2836823B2 (he)
KR (1) KR930000274B1 (he)
AT (1) ATE111518T1 (he)
AU (1) AU604139B2 (he)
CA (1) CA1341223C (he)
DE (1) DE3851511T2 (he)
DK (1) DK173536B1 (he)
ES (1) ES2063769T3 (he)
FI (1) FI93365C (he)
IE (1) IE65393B1 (he)
IL (1) IL87171A (he)
NO (2) NO310466B1 (he)
NZ (1) NZ225535A (he)
PT (1) PT88076B (he)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378614A (en) * 1989-08-18 1995-01-03 Novo Nordisk A/S Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
ES2086521T3 (es) * 1990-01-25 1996-07-01 Univ Washington Proteina hibrida laci-factor x.
ATE135585T1 (de) * 1990-08-27 1996-04-15 Monsanto Co Anticoagulatorische zusammensetzung aus laci und sulfatierten polysacchariden
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
US5346991A (en) * 1991-06-13 1994-09-13 Genentech, Inc. Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders
US5276015A (en) * 1992-03-18 1994-01-04 Washington University Method of inhibiting microvascular thrombosis
US20030171292A1 (en) 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US5455338A (en) 1993-11-05 1995-10-03 Zymogenetics, Inc. DNA encoding novel human kunitz-type inhibitors and methods relating thereto
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
CN1604790A (zh) 2001-10-15 2005-04-06 希龙公司 通过施用组织因子途径抑制剂(tfpi)治疗严重性肺炎
PT2311432E (pt) 2002-06-07 2015-02-09 Dyax Corp Polipeptídeos de domínio kunitz modificado e sua utilização para a redução de isquemia ou aparecimento de uma resposta inflamatória sistémica associada a um procedimento cirúrgico
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
SI1981519T1 (en) 2005-12-29 2018-05-31 Dyax Corp. INHIBITION PROTEAZE
ES2773766T3 (es) 2008-12-19 2020-07-14 Baxalta GmbH Inhibidores de TFPI y métodos de uso
AU2010203712A1 (en) 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
LT2521568T (lt) 2010-01-06 2018-12-10 Dyax Corp. Plazmos kalikreiną surišantys baltymai
AU2011227714B2 (en) 2010-03-19 2014-09-04 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
CN105713092B (zh) 2011-01-06 2019-09-10 戴埃克斯有限公司 血浆前激肽释放酶结合蛋白
BR112013032235A2 (pt) * 2011-06-15 2016-11-22 Hoffmann La Roche anticorpos do receptor de epo anti-humano e métodos de uso
CA2867363C (en) 2012-03-21 2023-02-28 Baxter International Inc. Tfpi inhibitors and methods of use
AU2016366557B2 (en) 2015-12-11 2024-01-25 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
IL87172A (he) * 1987-07-23 1994-12-29 Univ Washington שיטה לבידוד מעכב של גורם רקמתי טהורביותר

Also Published As

Publication number Publication date
JP2002097200A (ja) 2002-04-02
DK173536B1 (da) 2001-02-05
AU1928788A (en) 1989-05-25
AU604139B2 (en) 1990-12-06
DE3851511T2 (de) 1995-03-30
JP2004201696A (ja) 2004-07-22
NO20013608D0 (no) 2001-07-20
ATE111518T1 (de) 1994-09-15
JP2005306875A (ja) 2005-11-04
NZ225535A (en) 1990-11-27
JP4025035B2 (ja) 2007-12-19
EP0318451B1 (en) 1994-09-14
JP2836823B2 (ja) 1998-12-14
IL87171A0 (en) 1988-12-30
FI883487A (fi) 1989-05-24
DE3851511D1 (de) 1994-10-20
NO310466B1 (no) 2001-07-09
EP0318451A3 (en) 1990-03-28
NO883270D0 (no) 1988-07-22
DK413488D0 (da) 1988-07-22
FI93365C (fi) 1995-03-27
JP3565714B2 (ja) 2004-09-15
KR890007750A (ko) 1989-07-05
IE65393B1 (en) 1995-10-18
FI883487A0 (fi) 1988-07-22
KR930000274B1 (ko) 1993-01-14
DK413488A (da) 1989-05-24
CA1341223C (en) 2001-05-01
JPH01165383A (ja) 1989-06-29
PT88076B (pt) 1993-01-29
IE882243L (en) 1989-05-23
ES2063769T3 (es) 1995-01-16
PT88076A (pt) 1988-08-01
NO20013608L (no) 1989-05-24
JPH1175875A (ja) 1999-03-23
EP0318451A2 (en) 1989-05-31
NO883270L (no) 1989-05-24
FI93365B (fi) 1994-12-15

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US4966852A (en) DNA clone of human tissue factor inhibitor
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