DK173536B1 - cDNA-sekvens, som koder for modent humant vævsfaktorinhibitor-protein - Google Patents

cDNA-sekvens, som koder for modent humant vævsfaktorinhibitor-protein Download PDF

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Publication number
DK173536B1
DK173536B1 DK198804134A DK413488A DK173536B1 DK 173536 B1 DK173536 B1 DK 173536B1 DK 198804134 A DK198804134 A DK 198804134A DK 413488 A DK413488 A DK 413488A DK 173536 B1 DK173536 B1 DK 173536B1
Authority
DK
Denmark
Prior art keywords
tfi
sequence
cdna
protein
tissue factor
Prior art date
Application number
DK198804134A
Other languages
Danish (da)
English (en)
Other versions
DK413488D0 (da
DK413488A (da
Inventor
Kuniko Kusano Kretzmer
Tze-Chein Wun
John Broze George Jr
Original Assignee
Univ Washington
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22410671&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK173536(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/123,753 external-priority patent/US4966852A/en
Application filed by Univ Washington, Monsanto Co filed Critical Univ Washington
Publication of DK413488D0 publication Critical patent/DK413488D0/da
Publication of DK413488A publication Critical patent/DK413488A/da
Priority to DK200001612A priority Critical patent/DK174754B1/da
Application granted granted Critical
Publication of DK173536B1 publication Critical patent/DK173536B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198804134A 1987-11-23 1988-07-22 cDNA-sekvens, som koder for modent humant vævsfaktorinhibitor-protein DK173536B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK200001612A DK174754B1 (da) 1987-11-23 2000-10-27 Humane vævsfaktorinhibitor (TFI), antistof med bindingsspecificitet herfor, fremgangsmåde til anvendelse af en TFI-peptid-kolonne til at oprense et antistof og fremgangsmåder til detektion af TFI eller et polypeptid omfattende....

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/123,753 US4966852A (en) 1987-07-23 1987-11-23 DNA clone of human tissue factor inhibitor
US12375387 1987-11-23

Publications (3)

Publication Number Publication Date
DK413488D0 DK413488D0 (da) 1988-07-22
DK413488A DK413488A (da) 1989-05-24
DK173536B1 true DK173536B1 (da) 2001-02-05

Family

ID=22410671

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198804134A DK173536B1 (da) 1987-11-23 1988-07-22 cDNA-sekvens, som koder for modent humant vævsfaktorinhibitor-protein

Country Status (15)

Country Link
EP (1) EP0318451B1 (he)
JP (5) JP2836823B2 (he)
KR (1) KR930000274B1 (he)
AT (1) ATE111518T1 (he)
AU (1) AU604139B2 (he)
CA (1) CA1341223C (he)
DE (1) DE3851511T2 (he)
DK (1) DK173536B1 (he)
ES (1) ES2063769T3 (he)
FI (1) FI93365C (he)
IE (1) IE65393B1 (he)
IL (1) IL87171A (he)
NO (2) NO310466B1 (he)
NZ (1) NZ225535A (he)
PT (1) PT88076B (he)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378614A (en) * 1989-08-18 1995-01-03 Novo Nordisk A/S Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
DE69117545T2 (de) * 1990-01-25 1996-10-31 Univ Washington Faktor X-LACI-Hybridprotein
ES2085462T3 (es) * 1990-08-27 1996-06-01 Monsanto Co Combinacion anticoagulante de laci y de polisacaridos sulfatados.
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
US5346991A (en) * 1991-06-13 1994-09-13 Genentech, Inc. Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders
US5276015A (en) * 1992-03-18 1994-01-04 Washington University Method of inhibiting microvascular thrombosis
US20030171292A1 (en) 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US5455338A (en) 1993-11-05 1995-10-03 Zymogenetics, Inc. DNA encoding novel human kunitz-type inhibitors and methods relating thereto
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
BR0213292A (pt) 2001-10-15 2006-05-23 Chiron Corp tratamento de pneumonia severa por administração de inibidor da via de fator tecidual (tfpi)
WO2003103475A2 (en) 2002-06-07 2003-12-18 Dyax Corp. Prevention and reduction of blood loss
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
PT1981519T (pt) 2005-12-29 2018-02-23 Dyax Corp Inibição de protéases
ES2773766T3 (es) 2008-12-19 2020-07-14 Baxalta GmbH Inhibidores de TFPI y métodos de uso
CN102307594A (zh) 2009-01-06 2012-01-04 戴埃克斯有限公司 用激肽释放酶抑制剂治疗粘膜炎
HUE039605T2 (hu) 2010-01-06 2019-01-28 Dyax Corp Plazma kallikreint kötõ proteinek
AU2011227714B2 (en) 2010-03-19 2014-09-04 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
KR102320178B1 (ko) 2011-01-06 2021-11-02 다케다 파머수티컬 컴패니 리미티드 혈장 칼리크레인 결합 단백질
CA2837914A1 (en) 2011-06-15 2012-12-20 F. Hoffmann-La Roche Ag Anti-human epo receptor antibodies and methods of use
AU2013235741C1 (en) 2012-03-21 2017-12-21 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
NZ744233A (en) 2015-12-11 2023-11-24 Takeda Pharmaceuticals Co Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
IL87172A (he) * 1987-07-23 1994-12-29 Univ Washington שיטה לבידוד מעכב של גורם רקמתי טהורביותר

Also Published As

Publication number Publication date
ATE111518T1 (de) 1994-09-15
JP2005306875A (ja) 2005-11-04
DK413488D0 (da) 1988-07-22
NO883270D0 (no) 1988-07-22
FI93365C (fi) 1995-03-27
EP0318451B1 (en) 1994-09-14
CA1341223C (en) 2001-05-01
IL87171A (he) 1995-08-31
KR890007750A (ko) 1989-07-05
PT88076B (pt) 1993-01-29
NZ225535A (en) 1990-11-27
JPH01165383A (ja) 1989-06-29
EP0318451A3 (en) 1990-03-28
AU604139B2 (en) 1990-12-06
NO310466B1 (no) 2001-07-09
JP2004201696A (ja) 2004-07-22
JPH1175875A (ja) 1999-03-23
JP2836823B2 (ja) 1998-12-14
NO20013608D0 (no) 2001-07-20
PT88076A (pt) 1988-08-01
FI883487A (fi) 1989-05-24
IE882243L (en) 1989-05-23
JP4025035B2 (ja) 2007-12-19
NO20013608L (no) 1989-05-24
IE65393B1 (en) 1995-10-18
JP3565714B2 (ja) 2004-09-15
NO883270L (no) 1989-05-24
DE3851511D1 (de) 1994-10-20
DE3851511T2 (de) 1995-03-30
KR930000274B1 (ko) 1993-01-14
AU1928788A (en) 1989-05-25
FI883487A0 (fi) 1988-07-22
IL87171A0 (en) 1988-12-30
DK413488A (da) 1989-05-24
FI93365B (fi) 1994-12-15
ES2063769T3 (es) 1995-01-16
EP0318451A2 (en) 1989-05-31
JP2002097200A (ja) 2002-04-02

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