DE3851511D1 - DNA-Klon für menschlichen Gewebefaktorinhibitor. - Google Patents

DNA-Klon für menschlichen Gewebefaktorinhibitor.

Info

Publication number
DE3851511D1
DE3851511D1 DE3851511T DE3851511T DE3851511D1 DE 3851511 D1 DE3851511 D1 DE 3851511D1 DE 3851511 T DE3851511 T DE 3851511T DE 3851511 T DE3851511 T DE 3851511T DE 3851511 D1 DE3851511 D1 DE 3851511D1
Authority
DE
Germany
Prior art keywords
human tissue
tissue factor
factor inhibitor
dna clone
tfi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3851511T
Other languages
English (en)
Other versions
DE3851511T2 (de
Inventor
George John Broze
Kuniko Kusano Kretzmer
Tze-Chein Wun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Monsanto Co
Washington University in St Louis WUSTL
Original Assignee
University of Washington
Monsanto Co
Washington University in St Louis WUSTL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22410671&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3851511(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/123,753 external-priority patent/US4966852A/en
Application filed by University of Washington, Monsanto Co, Washington University in St Louis WUSTL filed Critical University of Washington
Publication of DE3851511D1 publication Critical patent/DE3851511D1/de
Application granted granted Critical
Publication of DE3851511T2 publication Critical patent/DE3851511T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE3851511T 1987-11-23 1988-07-22 DNA-Klon für menschlichen Gewebefaktorinhibitor. Expired - Lifetime DE3851511T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/123,753 US4966852A (en) 1987-07-23 1987-11-23 DNA clone of human tissue factor inhibitor

Publications (2)

Publication Number Publication Date
DE3851511D1 true DE3851511D1 (de) 1994-10-20
DE3851511T2 DE3851511T2 (de) 1995-03-30

Family

ID=22410671

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3851511T Expired - Lifetime DE3851511T2 (de) 1987-11-23 1988-07-22 DNA-Klon für menschlichen Gewebefaktorinhibitor.

Country Status (15)

Country Link
EP (1) EP0318451B1 (de)
JP (5) JP2836823B2 (de)
KR (1) KR930000274B1 (de)
AT (1) ATE111518T1 (de)
AU (1) AU604139B2 (de)
CA (1) CA1341223C (de)
DE (1) DE3851511T2 (de)
DK (1) DK173536B1 (de)
ES (1) ES2063769T3 (de)
FI (1) FI93365C (de)
IE (1) IE65393B1 (de)
IL (1) IL87171A (de)
NO (2) NO310466B1 (de)
NZ (1) NZ225535A (de)
PT (1) PT88076B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
US5378614A (en) * 1989-08-18 1995-01-03 Novo Nordisk A/S Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast
ES2086521T3 (es) * 1990-01-25 1996-07-01 Univ Washington Proteina hibrida laci-factor x.
PT98779B (pt) * 1990-08-27 1999-06-30 Monsanto Co Processo para a preparacao de uma composicao anticoagulante contendo inibidor sulfatados e metodos para a sua utilizacao
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
US5346991A (en) * 1991-06-13 1994-09-13 Genentech, Inc. Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders
US5276015A (en) * 1992-03-18 1994-01-04 Washington University Method of inhibiting microvascular thrombosis
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US20030171292A1 (en) 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US5455338A (en) * 1993-11-05 1995-10-03 Zymogenetics, Inc. DNA encoding novel human kunitz-type inhibitors and methods relating thereto
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
IL161408A0 (en) 2001-10-15 2004-09-27 Chiron Corp Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi)
ATE477020T1 (de) 2002-06-07 2010-08-15 Dyax Corp Prevention und verringerung von ischemia
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
HUE038243T2 (hu) 2005-12-29 2018-10-29 Dyax Corp Proteáz gátlás
SI2379096T1 (sl) 2008-12-19 2020-03-31 Baxalta GmbH Zaviralci TFPI in postopki uporabe
EP2385843A4 (de) 2009-01-06 2013-02-27 Dyax Corp Behandlung von mukositis mit kallikrein-hemmern
CA3168591A1 (en) 2010-01-06 2011-07-14 Takeda Pharmaceutical Company Limited Plasma kallikrein binding proteins
WO2011115712A2 (en) 2010-03-19 2011-09-22 Baxter International Inc Tfpi inhibitors and methods of use
JP2014506257A (ja) 2011-01-06 2014-03-13 ダイアックス コーポレーション 血漿カリクレイン結合タンパク質
WO2012171996A1 (en) * 2011-06-15 2012-12-20 F. Hoffmann-La Roche Ag Anti-human epo receptor antibodies and methods of use
DK2827883T3 (da) 2012-03-21 2019-07-29 Baxalta GmbH Tfpi-inhibitorer og fremgangsmåder til anvendelse
EP3387018A1 (de) 2015-12-11 2018-10-17 Dyax Corp. Plasma-kallikrein-inhibitoren und verwendungen davon zur behandlung von hereditärem angioödem

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
IL87172A (en) * 1987-07-23 1994-12-29 Univ Washington A method of inhibiting the isolation of a purer tissue factor

Also Published As

Publication number Publication date
NZ225535A (en) 1990-11-27
NO310466B1 (no) 2001-07-09
CA1341223C (en) 2001-05-01
EP0318451B1 (de) 1994-09-14
PT88076B (pt) 1993-01-29
FI883487A0 (fi) 1988-07-22
JPH01165383A (ja) 1989-06-29
KR930000274B1 (ko) 1993-01-14
FI883487A (fi) 1989-05-24
ATE111518T1 (de) 1994-09-15
JP2005306875A (ja) 2005-11-04
FI93365C (fi) 1995-03-27
NO20013608D0 (no) 2001-07-20
NO883270L (no) 1989-05-24
JPH1175875A (ja) 1999-03-23
IL87171A0 (en) 1988-12-30
IE65393B1 (en) 1995-10-18
DK413488D0 (da) 1988-07-22
DK413488A (da) 1989-05-24
FI93365B (fi) 1994-12-15
NO20013608L (no) 1989-05-24
AU604139B2 (en) 1990-12-06
JP4025035B2 (ja) 2007-12-19
EP0318451A3 (en) 1990-03-28
KR890007750A (ko) 1989-07-05
JP2002097200A (ja) 2002-04-02
DE3851511T2 (de) 1995-03-30
JP3565714B2 (ja) 2004-09-15
JP2836823B2 (ja) 1998-12-14
IE882243L (en) 1989-05-23
EP0318451A2 (de) 1989-05-31
DK173536B1 (da) 2001-02-05
JP2004201696A (ja) 2004-07-22
PT88076A (pt) 1988-08-01
NO883270D0 (no) 1988-07-22
AU1928788A (en) 1989-05-25
ES2063769T3 (es) 1995-01-16
IL87171A (en) 1995-08-31

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Legal Events

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8364 No opposition during term of opposition