DK413488A - Dna-klon med en basissekvens for human vaevsfaktorinhibitor (tfi) og dna-sekvens, der koder for tfi - Google Patents

Dna-klon med en basissekvens for human vaevsfaktorinhibitor (tfi) og dna-sekvens, der koder for tfi

Info

Publication number
DK413488A
DK413488A DK413488A DK413488A DK413488A DK 413488 A DK413488 A DK 413488A DK 413488 A DK413488 A DK 413488A DK 413488 A DK413488 A DK 413488A DK 413488 A DK413488 A DK 413488A
Authority
DK
Denmark
Prior art keywords
tfi
dna
human tissue
tissue factor
factor inhibitor
Prior art date
Application number
DK413488A
Other languages
English (en)
Other versions
DK173536B1 (da
DK413488D0 (da
Inventor
Jr George John Broze
Kuniko Kusano Kretzmer
Tze-Chein Wun
Original Assignee
Monsanto Co
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22410671&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK413488(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/123,753 external-priority patent/US4966852A/en
Application filed by Monsanto Co, Univ Washington filed Critical Monsanto Co
Publication of DK413488D0 publication Critical patent/DK413488D0/da
Publication of DK413488A publication Critical patent/DK413488A/da
Priority to DK200001612A priority Critical patent/DK174754B1/da
Application granted granted Critical
Publication of DK173536B1 publication Critical patent/DK173536B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
DK198804134A 1987-11-23 1988-07-22 cDNA-sekvens, som koder for modent humant vævsfaktorinhibitor-protein DK173536B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK200001612A DK174754B1 (da) 1987-11-23 2000-10-27 Humane vævsfaktorinhibitor (TFI), antistof med bindingsspecificitet herfor, fremgangsmåde til anvendelse af en TFI-peptid-kolonne til at oprense et antistof og fremgangsmåder til detektion af TFI eller et polypeptid omfattende....

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12375387 1987-11-23
US07/123,753 US4966852A (en) 1987-07-23 1987-11-23 DNA clone of human tissue factor inhibitor

Publications (3)

Publication Number Publication Date
DK413488D0 DK413488D0 (da) 1988-07-22
DK413488A true DK413488A (da) 1989-05-24
DK173536B1 DK173536B1 (da) 2001-02-05

Family

ID=22410671

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198804134A DK173536B1 (da) 1987-11-23 1988-07-22 cDNA-sekvens, som koder for modent humant vævsfaktorinhibitor-protein

Country Status (15)

Country Link
EP (1) EP0318451B1 (da)
JP (5) JP2836823B2 (da)
KR (1) KR930000274B1 (da)
AT (1) ATE111518T1 (da)
AU (1) AU604139B2 (da)
CA (1) CA1341223C (da)
DE (1) DE3851511T2 (da)
DK (1) DK173536B1 (da)
ES (1) ES2063769T3 (da)
FI (1) FI93365C (da)
IE (1) IE65393B1 (da)
IL (1) IL87171A (da)
NO (2) NO310466B1 (da)
NZ (1) NZ225535A (da)
PT (1) PT88076B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner
US5378614A (en) * 1989-08-18 1995-01-03 Novo Nordisk A/S Vector and method for making tissue factor pathway inhibitor (TFPI) analogues in yeast
ATE135044T1 (de) * 1990-01-25 1996-03-15 Univ Washington Faktor x-laci-hybridprotein
PT98779B (pt) * 1990-08-27 1999-06-30 Monsanto Co Processo para a preparacao de uma composicao anticoagulante contendo inibidor sulfatados e metodos para a sua utilizacao
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
US5346991A (en) * 1991-06-13 1994-09-13 Genentech, Inc. Tissue factor mutants useful for the treatment of myocardial infarction and coagulopathic disorders
US5276015A (en) * 1992-03-18 1994-01-04 Washington University Method of inhibiting microvascular thrombosis
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US20030171292A1 (en) 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US5455338A (en) * 1993-11-05 1995-10-03 Zymogenetics, Inc. DNA encoding novel human kunitz-type inhibitors and methods relating thereto
US6057287A (en) 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
MXPA04003547A (es) 2001-10-15 2004-07-22 Chiron Corp Tratamiento de sepsis mediante administracion de dosis bajas de inhibidor de via factor de tejido.
EP2298278B1 (en) 2002-06-07 2015-11-11 Dyax Corp. Prevention and reduction of blood loss and inflammatory response
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US8828703B2 (en) 2005-12-29 2014-09-09 Dyax Corp. Protease inhibition
BR122021014783B1 (pt) 2008-12-19 2023-03-14 Baxalta GmbH Peptídeo que se liga a tfpi, uso do peptídeo, composição farmacêutica e método para purificação de tfpi
AU2010203712A1 (en) 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
RS62853B1 (sr) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Proteini koji vezuju kalikrein plazme
CN103025345B (zh) 2010-03-19 2016-01-20 巴克斯特国际公司 Tfpi抑制剂及使用方法
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
BR112013032235A2 (pt) 2011-06-15 2016-11-22 Hoffmann La Roche anticorpos do receptor de epo anti-humano e métodos de uso
AU2013235741C1 (en) 2012-03-21 2017-12-21 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
US11286307B2 (en) 2015-12-11 2022-03-29 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4775624A (en) * 1985-02-08 1988-10-04 Eli Lilly And Company Vectors and compounds for expression of human protein C
IL87172A (en) * 1987-07-23 1994-12-29 Univ Washington A method of inhibiting the isolation of a purer tissue factor

Also Published As

Publication number Publication date
AU604139B2 (en) 1990-12-06
JP2004201696A (ja) 2004-07-22
JPH1175875A (ja) 1999-03-23
ES2063769T3 (es) 1995-01-16
AU1928788A (en) 1989-05-25
DE3851511T2 (de) 1995-03-30
EP0318451A3 (en) 1990-03-28
FI93365C (fi) 1995-03-27
JPH01165383A (ja) 1989-06-29
NO20013608L (no) 1989-05-24
IE65393B1 (en) 1995-10-18
JP4025035B2 (ja) 2007-12-19
KR930000274B1 (ko) 1993-01-14
ATE111518T1 (de) 1994-09-15
NZ225535A (en) 1990-11-27
IL87171A (en) 1995-08-31
EP0318451B1 (en) 1994-09-14
FI883487A0 (fi) 1988-07-22
JP3565714B2 (ja) 2004-09-15
NO883270L (no) 1989-05-24
EP0318451A2 (en) 1989-05-31
IE882243L (en) 1989-05-23
KR890007750A (ko) 1989-07-05
PT88076B (pt) 1993-01-29
DK173536B1 (da) 2001-02-05
IL87171A0 (en) 1988-12-30
NO20013608D0 (no) 2001-07-20
DE3851511D1 (de) 1994-10-20
NO310466B1 (no) 2001-07-09
JP2836823B2 (ja) 1998-12-14
PT88076A (pt) 1988-08-01
NO883270D0 (no) 1988-07-22
CA1341223C (en) 2001-05-01
FI883487A (fi) 1989-05-24
DK413488D0 (da) 1988-07-22
JP2002097200A (ja) 2002-04-02
JP2005306875A (ja) 2005-11-04
FI93365B (fi) 1994-12-15

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B1 Patent granted (law 1993)
PBP Patent lapsed

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