IL69246A - 7-((2-aminothiazolyl-2-pyrrolidonyl or(piperidonyl)-oxyimino)acetamido)cephem carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

7-((2-aminothiazolyl-2-pyrrolidonyl or(piperidonyl)-oxyimino)acetamido)cephem carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL69246A
IL69246A IL69246A IL6924683A IL69246A IL 69246 A IL69246 A IL 69246A IL 69246 A IL69246 A IL 69246A IL 6924683 A IL6924683 A IL 6924683A IL 69246 A IL69246 A IL 69246A
Authority
IL
Israel
Prior art keywords
preparation
aminothiazolyl
oxyimino
pyrrolidonyl
piperidonyl
Prior art date
Application number
IL69246A
Other languages
English (en)
Other versions
IL69246A0 (en
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Priority to IL71327A priority Critical patent/IL71327A/xx
Publication of IL69246A0 publication Critical patent/IL69246A0/xx
Priority to IL71327A priority patent/IL71327A0/xx
Publication of IL69246A publication Critical patent/IL69246A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
IL69246A 1982-08-07 1983-07-15 7-((2-aminothiazolyl-2-pyrrolidonyl or(piperidonyl)-oxyimino)acetamido)cephem carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL69246A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL71327A IL71327A (en) 1982-08-07 1983-07-15 2-(aminothiazolyl)-2-oximino acetic acid derivatives and their preparation
IL71327A IL71327A0 (en) 1982-08-07 1984-03-23 Thiazolylacetic acid derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8222823 1982-08-07

Publications (2)

Publication Number Publication Date
IL69246A0 IL69246A0 (en) 1983-11-30
IL69246A true IL69246A (en) 1986-07-31

Family

ID=10532181

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69246A IL69246A (en) 1982-08-07 1983-07-15 7-((2-aminothiazolyl-2-pyrrolidonyl or(piperidonyl)-oxyimino)acetamido)cephem carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (4) US4598075A (zh)
EP (2) EP0245619B1 (zh)
JP (3) JPS5951292A (zh)
KR (1) KR870001440B1 (zh)
AT (2) ATE35413T1 (zh)
AU (1) AU562248B2 (zh)
BG (3) BG42835A3 (zh)
CA (1) CA1231940A (zh)
CS (2) CS236798B2 (zh)
DD (1) DD210053A5 (zh)
DE (2) DE3381734D1 (zh)
DK (2) DK358983A (zh)
ES (3) ES8502121A1 (zh)
FI (1) FI74972C (zh)
GR (1) GR78864B (zh)
IE (1) IE55406B1 (zh)
IL (1) IL69246A (zh)
NO (1) NO161068C (zh)
PH (1) PH18498A (zh)
PL (2) PL139932B1 (zh)
PT (1) PT77166B (zh)
SU (2) SU1227116A3 (zh)
ZA (1) ZA835411B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE55406B1 (en) * 1982-08-07 1990-09-12 Tanabe Seiyaku Co Novel cephalosporin compounds and preparation thereof
JPS60132983A (ja) * 1983-12-21 1985-07-16 Tanabe Seiyaku Co Ltd チアゾ−ル酢酸誘導体及びその製法
JPS6178792A (ja) * 1984-09-26 1986-04-22 Yamanouchi Pharmaceut Co Ltd ７−〔α−（２−アミノ−４−チアゾリル）−α−（４−オキソ−２−アゼチジニル置換イミノ）アセトアミド〕−３−置換メチル−Δ↑３−セフエム−４−カルボン酸およびその製造法
JPS6185392A (ja) * 1984-10-03 1986-04-30 Tanabe Seiyaku Co Ltd セフアロスポリン化合物の新規製法
JPS61143379A (ja) * 1984-12-14 1986-07-01 Tanabe Seiyaku Co Ltd チアゾ−ル酢酸誘導体の製法
JPS61143380A (ja) * 1984-12-14 1986-07-01 Tanabe Seiyaku Co Ltd チアゾ−ル酢酸誘導体の製法
JPS61143381A (ja) * 1984-12-14 1986-07-01 Tanabe Seiyaku Co Ltd 光学活性チアゾ−ル酢酸誘導体の製法
CA1263399A (en) * 1984-12-19 1989-11-28 Hoffmann-La Roche Limited Process for the manufacture of aminothiazole acetic acid derivatives
JPS61171464A (ja) * 1985-01-23 1986-08-02 Dai Ichi Seiyaku Co Ltd オキシイミノ酪酸誘導体の製法
JPS63107989A (ja) * 1986-06-04 1988-05-12 Tanabe Seiyaku Co Ltd セファロスポリン化合物
IL82738A0 (en) * 1986-06-16 1987-12-20 Tanabe Seiyaku Co Cephalosporin compounds,their preparation and pharmaceutical compositions containing them
AT389701B (de) * 1987-10-08 1990-01-25 Tanabe Seiyaku Co Neue cephalosporinverbindungen und diese enthaltende pharmazeutische zusammensetzungen
JP4773154B2 (ja) * 2005-07-29 2011-09-14 小澤物産株式会社 レバー式カップリング

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
IE44888B1 (en) * 1976-03-09 1982-05-05 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation theroef
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
FR2384782A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
SE448379B (sv) * 1978-03-31 1987-02-16 Roussel Uclaf O-substituerade oximderivat av 7-amino-tiazolyl-acetamidocefalosporansyra
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
DE2967356D1 (en) * 1978-07-17 1985-02-28 Fujisawa Pharmaceutical Co Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
GB2028305A (en) * 1978-08-03 1980-03-05 Hoechst Ag Cephem derivatives and processes for their manufacture
GB2061276B (en) * 1979-10-25 1983-05-25 Squibb & Sons Inc Imidazole and tetrazole derivatives of 7-((2-amino-4-thiazolyl)-oximino)cephalosporins
US4271157A (en) * 1980-02-28 1981-06-02 E. R. Squibb & Sons, Inc. Imidazole derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
US4416879A (en) * 1980-09-08 1983-11-22 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
IE55406B1 (en) * 1982-08-07 1990-09-12 Tanabe Seiyaku Co Novel cephalosporin compounds and preparation thereof
JPS59155391A (ja) * 1983-02-22 1984-09-04 Tanabe Seiyaku Co Ltd 新規セファロスポリン誘導体

Also Published As

Publication number Publication date
JPH0246588B2 (zh) 1990-10-16
FI832770A0 (fi) 1983-08-02
PH18498A (en) 1985-08-02
PL139932B1 (en) 1987-03-31
FI832770A (fi) 1984-02-08
ZA835411B (en) 1984-03-28
ES524775A0 (es) 1984-12-16
ES8502121A1 (es) 1984-12-16
NO161068B (no) 1989-03-20
DD210053A5 (de) 1984-05-30
CS196483A2 (en) 1985-08-22
NO832828L (no) 1984-02-08
CS236798B2 (en) 1985-05-15
US4742174A (en) 1988-05-03
DE3377213D1 (en) 1988-08-04
SU1324586A3 (ru) 1987-07-15
DK358983A (da) 1984-02-08
DK358983D0 (da) 1983-08-05
ATE35413T1 (de) 1988-07-15
EP0101265A3 (en) 1985-04-10
JPS5951292A (ja) 1984-03-24
ATE54450T1 (de) 1990-07-15
US4598075A (en) 1986-07-01
PL140023B1 (en) 1987-03-31
DK361587A (da) 1987-07-10
GR78864B (zh) 1984-10-02
PL249964A1 (en) 1985-05-07
BG40967A3 (en) 1987-03-14
AU562248B2 (en) 1987-06-04
JPH0360803B2 (zh) 1991-09-17
AU1710483A (en) 1984-02-09
BG42835A3 (en) 1988-02-15
PT77166A (en) 1983-09-01
PT77166B (pt) 1986-01-28
DE3381734D1 (de) 1990-08-16
JPS62294615A (ja) 1987-12-22
JPH0145473B2 (zh) 1989-10-03
EP0101265B1 (en) 1988-06-29
US4727071A (en) 1988-02-23
IE831648L (en) 1984-02-07
ES531296A0 (es) 1985-08-01
KR870001440B1 (ko) 1987-08-06
NO161068C (no) 1989-06-28
ES535281A0 (es) 1985-12-16
EP0101265A2 (en) 1984-02-22
CS243484B2 (en) 1986-06-12
ES8603496A1 (es) 1985-12-16
DK361587D0 (da) 1987-07-10
PL243329A1 (en) 1985-02-13
KR840005816A (ko) 1984-11-19
FI74972C (fi) 1988-04-11
FI74972B (fi) 1987-12-31
US4598154A (en) 1986-07-01
IL69246A0 (en) 1983-11-30
ES8506707A1 (es) 1985-08-01
EP0245619B1 (en) 1990-07-11
SU1227116A3 (ru) 1986-04-23
EP0245619A1 (en) 1987-11-19
CA1231940A (en) 1988-01-26
IE55406B1 (en) 1990-09-12
JPS62294681A (ja) 1987-12-22
BG37838A3 (en) 1985-08-15

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