FI832770A0 - Nya cephalosporin foerbindningar och deras framstaellningssaett - Google Patents

Nya cephalosporin foerbindningar och deras framstaellningssaett

Info

Publication number
FI832770A0
FI832770A0 FI832770A FI832770A FI832770A0 FI 832770 A0 FI832770 A0 FI 832770A0 FI 832770 A FI832770 A FI 832770A FI 832770 A FI832770 A FI 832770A FI 832770 A0 FI832770 A0 FI 832770A0
Authority
FI
Finland
Prior art keywords
cephalosporin
framstaellningssaett
foerbindningar
nya
och deras
Prior art date
Application number
FI832770A
Other languages
English (en)
Other versions
FI832770A (fi
FI74972B (fi
FI74972C (fi
Inventor
Toyonari Oine
Hiroshi Sugano
Yoshihisa Yamada
Totaro Yamaguchi
Satoshi Ohshima
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of FI832770A0 publication Critical patent/FI832770A0/fi
Publication of FI832770A publication Critical patent/FI832770A/fi
Publication of FI74972B publication Critical patent/FI74972B/fi
Application granted granted Critical
Publication of FI74972C publication Critical patent/FI74972C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
FI832770A 1982-08-07 1983-08-02 Foerfarande foer framstaellning av farmaceutiskt vaerdefull 7 -/(z)-2-(2-aminotiazol/-4-yl)-2-oxi- imino-acetamido/-3-cefem-4-karboxylsyra. FI74972C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8222823 1982-08-07
GB8222823 1982-08-07

Publications (4)

Publication Number Publication Date
FI832770A0 true FI832770A0 (fi) 1983-08-02
FI832770A FI832770A (fi) 1984-02-08
FI74972B FI74972B (fi) 1987-12-31
FI74972C FI74972C (fi) 1988-04-11

Family

ID=10532181

Family Applications (1)

Application Number Title Priority Date Filing Date
FI832770A FI74972C (fi) 1982-08-07 1983-08-02 Foerfarande foer framstaellning av farmaceutiskt vaerdefull 7 -/(z)-2-(2-aminotiazol/-4-yl)-2-oxi- imino-acetamido/-3-cefem-4-karboxylsyra.

Country Status (23)

Country Link
US (4) US4598075A (fi)
EP (2) EP0245619B1 (fi)
JP (3) JPS5951292A (fi)
KR (1) KR870001440B1 (fi)
AT (2) ATE35413T1 (fi)
AU (1) AU562248B2 (fi)
BG (3) BG37838A3 (fi)
CA (1) CA1231940A (fi)
CS (2) CS236798B2 (fi)
DD (1) DD210053A5 (fi)
DE (2) DE3377213D1 (fi)
DK (2) DK358983A (fi)
ES (3) ES8502121A1 (fi)
FI (1) FI74972C (fi)
GR (1) GR78864B (fi)
IE (1) IE55406B1 (fi)
IL (1) IL69246A (fi)
NO (1) NO161068C (fi)
PH (1) PH18498A (fi)
PL (2) PL140023B1 (fi)
PT (1) PT77166B (fi)
SU (2) SU1227116A3 (fi)
ZA (1) ZA835411B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE55406B1 (en) * 1982-08-07 1990-09-12 Tanabe Seiyaku Co Novel cephalosporin compounds and preparation thereof
JPS60132983A (ja) * 1983-12-21 1985-07-16 Tanabe Seiyaku Co Ltd チアゾ−ル酢酸誘導体及びその製法
JPS6178792A (ja) * 1984-09-26 1986-04-22 Yamanouchi Pharmaceut Co Ltd 7−〔α−(2−アミノ−4−チアゾリル)−α−(4−オキソ−2−アゼチジニル置換イミノ)アセトアミド〕−3−置換メチル−Δ↑3−セフエム−4−カルボン酸およびその製造法
JPS6185392A (ja) * 1984-10-03 1986-04-30 Tanabe Seiyaku Co Ltd セフアロスポリン化合物の新規製法
JPS61143381A (ja) * 1984-12-14 1986-07-01 Tanabe Seiyaku Co Ltd 光学活性チアゾ−ル酢酸誘導体の製法
JPS61143379A (ja) * 1984-12-14 1986-07-01 Tanabe Seiyaku Co Ltd チアゾ−ル酢酸誘導体の製法
JPS61143380A (ja) * 1984-12-14 1986-07-01 Tanabe Seiyaku Co Ltd チアゾ−ル酢酸誘導体の製法
CA1263399A (en) * 1984-12-19 1989-11-28 Hoffmann-La Roche Limited Process for the manufacture of aminothiazole acetic acid derivatives
JPS61171464A (ja) * 1985-01-23 1986-08-02 Dai Ichi Seiyaku Co Ltd オキシイミノ酪酸誘導体の製法
JPS63107989A (ja) * 1986-06-04 1988-05-12 Tanabe Seiyaku Co Ltd セファロスポリン化合物
IL82738A0 (en) * 1986-06-16 1987-12-20 Tanabe Seiyaku Co Cephalosporin compounds,their preparation and pharmaceutical compositions containing them
AT389701B (de) * 1987-10-08 1990-01-25 Tanabe Seiyaku Co Neue cephalosporinverbindungen und diese enthaltende pharmazeutische zusammensetzungen
JP4773154B2 (ja) * 2005-07-29 2011-09-14 小澤物産株式会社 レバー式カップリング

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
IE44888B1 (en) * 1976-03-09 1982-05-05 Fujisawa Pharmaceutical Co 3,7-disubstituted-3-cephem-4-carboxylic acid compounds and processes for the preparation theroef
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
FR2384782A1 (fr) * 1977-03-25 1978-10-20 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
SE448379B (sv) * 1978-03-31 1987-02-16 Roussel Uclaf O-substituerade oximderivat av 7-amino-tiazolyl-acetamidocefalosporansyra
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
EP0009548B1 (en) * 1978-07-17 1985-01-16 Fujisawa Pharmaceutical Co., Ltd. Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
US4284631A (en) * 1978-07-31 1981-08-18 Fujisawa Pharmaceutical Co., Ltd. 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
GB2028305A (en) * 1978-08-03 1980-03-05 Hoechst Ag Cephem derivatives and processes for their manufacture
US4271157A (en) * 1980-02-28 1981-06-02 E. R. Squibb & Sons, Inc. Imidazole derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
GB2061276B (en) * 1979-10-25 1983-05-25 Squibb & Sons Inc Imidazole and tetrazole derivatives of 7-((2-amino-4-thiazolyl)-oximino)cephalosporins
US4416879A (en) * 1980-09-08 1983-11-22 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
IE55406B1 (en) * 1982-08-07 1990-09-12 Tanabe Seiyaku Co Novel cephalosporin compounds and preparation thereof
JPS59155391A (ja) * 1983-02-22 1984-09-04 Tanabe Seiyaku Co Ltd 新規セファロスポリン誘導体

Also Published As

Publication number Publication date
NO832828L (no) 1984-02-08
US4727071A (en) 1988-02-23
IL69246A0 (en) 1983-11-30
KR870001440B1 (ko) 1987-08-06
JPH0145473B2 (fi) 1989-10-03
JPS62294615A (ja) 1987-12-22
NO161068C (no) 1989-06-28
DK358983D0 (da) 1983-08-05
DK358983A (da) 1984-02-08
ATE54450T1 (de) 1990-07-15
PL249964A1 (en) 1985-05-07
BG40967A3 (en) 1987-03-14
SU1227116A3 (ru) 1986-04-23
DE3377213D1 (en) 1988-08-04
CA1231940A (en) 1988-01-26
AU562248B2 (en) 1987-06-04
DD210053A5 (de) 1984-05-30
IE55406B1 (en) 1990-09-12
FI832770A (fi) 1984-02-08
PT77166A (en) 1983-09-01
PT77166B (pt) 1986-01-28
EP0101265B1 (en) 1988-06-29
ZA835411B (en) 1984-03-28
ES8603496A1 (es) 1985-12-16
DK361587D0 (da) 1987-07-10
EP0101265A2 (en) 1984-02-22
BG37838A3 (en) 1985-08-15
BG42835A3 (en) 1988-02-15
SU1324586A3 (ru) 1987-07-15
JPH0246588B2 (fi) 1990-10-16
US4598154A (en) 1986-07-01
US4598075A (en) 1986-07-01
JPS62294681A (ja) 1987-12-22
CS243484B2 (en) 1986-06-12
PL139932B1 (en) 1987-03-31
PH18498A (en) 1985-08-02
US4742174A (en) 1988-05-03
FI74972B (fi) 1987-12-31
ES524775A0 (es) 1984-12-16
ES8502121A1 (es) 1984-12-16
ATE35413T1 (de) 1988-07-15
KR840005816A (ko) 1984-11-19
JPH0360803B2 (fi) 1991-09-17
GR78864B (fi) 1984-10-02
PL140023B1 (en) 1987-03-31
ES535281A0 (es) 1985-12-16
IE831648L (en) 1984-02-07
EP0101265A3 (en) 1985-04-10
DE3381734D1 (de) 1990-08-16
PL243329A1 (en) 1985-02-13
CS236798B2 (en) 1985-05-15
EP0245619A1 (en) 1987-11-19
ES531296A0 (es) 1985-08-01
JPS5951292A (ja) 1984-03-24
FI74972C (fi) 1988-04-11
NO161068B (no) 1989-03-20
IL69246A (en) 1986-07-31
DK361587A (da) 1987-07-10
CS196483A2 (en) 1985-08-22
EP0245619B1 (en) 1990-07-11
AU1710483A (en) 1984-02-09
ES8506707A1 (es) 1985-08-01

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: TANABE SEIYAKU CO., LTD.