GB1536281A - Cephem compounds - Google Patents

Cephem compounds

Info

Publication number
GB1536281A
GB1536281A GB24611/75A GB2461175A GB1536281A GB 1536281 A GB1536281 A GB 1536281A GB 24611/75 A GB24611/75 A GB 24611/75A GB 2461175 A GB2461175 A GB 2461175A GB 1536281 A GB1536281 A GB 1536281A
Authority
GB
United Kingdom
Prior art keywords
cephem compounds
cephem
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB24611/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to GB24611/75A priority Critical patent/GB1536281A/en
Priority to DK548875A priority patent/DK154939C/en
Priority to PH17868A priority patent/PH13731A/en
Priority to FR7538703A priority patent/FR2294690A1/en
Priority to DE2556736A priority patent/DE2556736C2/en
Priority to DE2559942A priority patent/DE2559942C2/en
Priority to MX752873U priority patent/MX5097E/en
Priority to MX830175U priority patent/MX6014E/en
Priority to GB28892/78A priority patent/GB1536283A/en
Priority to NO754296A priority patent/NO157933C/en
Priority to HU75TA00001381A priority patent/HU172304B/en
Priority to HU75TA1464A priority patent/HU179798B/en
Priority to SE7514286A priority patent/SE442202B/en
Priority to DE2560398A priority patent/DE2560398C2/en
Priority to NLAANVRAGE7514811,A priority patent/NL183703C/en
Priority to ES443627A priority patent/ES443627A1/en
Priority to BE162887A priority patent/BE836813A/en
Priority to CA000242004A priority patent/CA1216284A/en
Priority to AU87667/75A priority patent/AU500104B2/en
Priority to CH1655675A priority patent/CH624119A5/de
Priority to AT967775A priority patent/AT344894B/en
Priority to US05/642,356 priority patent/US4098888A/en
Priority to JP51067524A priority patent/JPS5822039B2/en
Priority to FR7635966A priority patent/FR2357552A1/en
Priority to ES457891A priority patent/ES457891A1/en
Priority to PH19987A priority patent/PH14161A/en
Priority to AT517277A priority patent/AT357521B/en
Priority to AT517177A priority patent/AT347587B/en
Priority to SE7713233A priority patent/SE444809B/en
Priority to CH1451477A priority patent/CH631437A5/en
Priority to ES464771A priority patent/ES464771A1/en
Priority to ES464772A priority patent/ES464772A1/en
Priority to DK552377A priority patent/DK155086C/en
Priority to US05/870,932 priority patent/US4205180A/en
Priority to NL7800731A priority patent/NL7800731A/en
Priority to US05/897,239 priority patent/US4203899A/en
Priority to CA000315026A priority patent/CA1137492A/en
Priority to CA315,025A priority patent/CA1128957A/en
Publication of GB1536281A publication Critical patent/GB1536281A/en
Priority to SE7902954A priority patent/SE445454B/en
Priority to FR7912111A priority patent/FR2434146A1/en
Priority to US06/071,032 priority patent/US4298606A/en
Priority to FR7924297A priority patent/FR2468599B1/en
Priority to CH407680A priority patent/CH633544A5/en
Priority to CH407580A priority patent/CH628058A5/en
Priority to NL8003054A priority patent/NL8003054A/en
Priority to JP56087403A priority patent/JPS5858353B2/en
Priority to HK22/82A priority patent/HK2282A/en
Priority to DK530282A priority patent/DK155218C/en
Priority to MY219/82A priority patent/MY8200219A/en
Priority to JP58012560A priority patent/JPS58185553A/en
Priority to US06/525,663 priority patent/US4514565A/en
Priority to JP58178160A priority patent/JPS5989686A/en
Priority to JP60232072A priority patent/JPS61143388A/en
Priority to US06/824,578 priority patent/US4668783A/en
Priority to US07/203,410 priority patent/US4973684A/en
Priority to US07/203,409 priority patent/US4912212A/en
Priority to US07/462,492 priority patent/US5583216A/en
Priority to BG98461A priority patent/BG60437B2/en
Priority to NL950016C priority patent/NL950016I1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB24611/75A 1974-12-19 1975-06-09 Cephem compounds Expired GB1536281A (en)

Priority Applications (59)

Application Number Priority Date Filing Date Title
GB24611/75A GB1536281A (en) 1975-06-09 1975-06-09 Cephem compounds
DK548875A DK154939C (en) 1974-12-19 1975-12-04 METHOD OF ANALOGUE FOR THE PREPARATION OF THIAZOLYLACETAMIDO-CEPHEM COMPOUNDS OR PHARMACEUTICAL ACCEPTABLE SALTS OR ESTERS THEREOF
PH17868A PH13731A (en) 1974-12-19 1975-12-15 Thiazolylacetamido derivatives of cephem compounds
FR7538703A FR2294690A1 (en) 1974-12-19 1975-12-17 THIAZO-LYLACETAMIDO COMPOUNDS
DE2556736A DE2556736C2 (en) 1974-12-19 1975-12-17 Cephem compounds and pharmaceuticals containing them
DE2559942A DE2559942C2 (en) 1974-12-19 1975-12-17 Oxyimino-β-oxo-γ-halobutyric acid derivatives protected in the α-position and their use for the preparation of corresponding 2-amino-thiazol-4-yl-acetic acid derivatives
MX752873U MX5097E (en) 1974-12-19 1975-12-17 PROCEDURE FOR PREPARING DERIVATIVES OF THIAZOLYLACETIC ACID
MX830175U MX6014E (en) 1974-12-19 1975-12-17 PROCEDURE FOR PREPARING CEPHALOSPORIN DERIVATIVES
GB28892/78A GB1536283A (en) 1974-12-19 1975-12-17 Alpha-protected oxyimino-beta-oxo-ypsilon-halogeno-butyric acid derivatives
NO754296A NO157933C (en) 1974-12-19 1975-12-17 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEFEM COMPOUNDS.
HU75TA00001381A HU172304B (en) 1975-06-09 1975-12-17 Process for producing 7-thiazolylacetamido-ceph-3-eme-4-carboxylic acid derivatives
HU75TA1464A HU179798B (en) 1974-12-19 1975-12-17 Process for preparing thiadiazolyl-acetic acid compounds
SE7514286A SE442202B (en) 1974-12-19 1975-12-17 ANALOGY PROCEDURE FOR PREPARING NEW CEPHALOSPORIN DERIVATIVES
DE2560398A DE2560398C2 (en) 1974-12-19 1975-12-17 2-Amino-thiazol-4-yl-acetic acid derivatives and processes for their preparation
NLAANVRAGE7514811,A NL183703C (en) 1974-12-19 1975-12-18 METHOD FOR PREPARING PHARMACEUTICAL PREPARATIONS WITH ANTIBIOTIC EFFICIENCY, AND METHOD FOR PREPARING ANTIBIOTIC ACTIVE CEPHAMIC COMPOUNDS.
ES443627A ES443627A1 (en) 1974-12-19 1975-12-18 Thiazolylacetamido cephalosporin type compounds
BE162887A BE836813A (en) 1974-12-19 1975-12-18 THIAZOLYACETAMIDO COMPOUNDS AND THEIR PREPARATION
CA000242004A CA1216284A (en) 1974-12-19 1975-12-18 Thiazolylacetamido compounds
AU87667/75A AU500104B2 (en) 1974-12-19 1975-12-18 Thiazolylagetamido cephems
CH1655675A CH624119A5 (en) 1974-12-19 1975-12-19
AT967775A AT344894B (en) 1975-06-09 1975-12-19 PROCESS FOR PRODUCING NEW CEPHEM CONNECTIONS
US05/642,356 US4098888A (en) 1974-12-19 1975-12-19 Thiazolylacetamido cephalosporin type compounds
JP51067524A JPS5822039B2 (en) 1975-06-09 1976-06-08 Thiazole compound and its manufacturing method
FR7635966A FR2357552A1 (en) 1974-12-19 1976-11-29 THIAZOLES SUBSTITUTES AND THEIR PREPARATION PROCESS
ES457891A ES457891A1 (en) 1974-12-19 1977-04-16 Thiazolylacetamido cephalosporin type compounds
PH19987A PH14161A (en) 1974-12-19 1977-07-12 Thiazolylacetamido compounds
AT517277A AT357521B (en) 1974-12-19 1977-07-18 METHOD FOR PRODUCING NEW THIAZOLYL ACETIC ACID COMPOUNDS
AT517177A AT347587B (en) 1975-06-09 1977-07-18 PROCESS FOR PRODUCING A NEW CEPHEM CONNECTION
SE7713233A SE444809B (en) 1975-06-09 1977-11-23 ALFA-PROTECTED OXIIMINO-BETA-OXO-GAMMA-HALOGENSORIC ACID DERIVATIVES FOR USE AS INTERMEDIATE FOR THE PREPARATION OF PHARMACEUTICAL USEFUL CEFEM SOCIETIES
CH1451477A CH631437A5 (en) 1974-12-19 1977-11-28 METHOD FOR PRODUCING NEW BUTTERIC ACID DERIVATIVES.
ES464771A ES464771A1 (en) 1974-12-19 1977-12-06 Thiazolylacetamido cephalosporin type compounds
ES464772A ES464772A1 (en) 1974-12-19 1977-12-06 Thiazolylacetamido cephalosporin type compounds
DK552377A DK155086C (en) 1974-12-19 1977-12-09 ALFA-PROTECTED OXYIMINO-BETA-OXO-GAMMA-HALOGENIC ACID DERIVATIVES FOR USING INTERMEDIATES IN THE PRODUCTION OF CEPHEM COMPOUNDS
US05/870,932 US4205180A (en) 1974-12-19 1978-01-18 α-Alkoxyimino-β-oxo-γ-Bromobutyric acid
NL7800731A NL7800731A (en) 1974-12-19 1978-01-20 (ALPHA) -PROTECTED OXYIMINO (BETA) -OXO GAMMA-HALOGEN BUTTER ACID DERIVATIVES.
US05/897,239 US4203899A (en) 1974-12-19 1978-04-17 Thiazolylacetamido compounds
CA000315026A CA1137492A (en) 1974-12-19 1978-10-31 Thiazolylacetic acid compounds
CA315,025A CA1128957A (en) 1974-12-19 1978-10-31 .alpha.-PROTECTED OXYIMINO-.beta.-OXO-.gamma.-HALOGENOBUTYRIC ACID DERIVATIVES
SE7902954A SE445454B (en) 1974-12-19 1979-04-03 AMINOTIAZOYLETIC ACID SUBSTANCES FOR USE AS INTERMEDIATE FOR THE PREPARATION OF ANTIBIOTICALLY EFFECTIVE CEPHALOSPORINE COMPOUNDS
FR7912111A FR2434146A1 (en) 1974-12-19 1979-05-11 DERIVATIVES OF A-HYDROXY IMINO BUTYRIC ACID AND THEIR PREPARATION
US06/071,032 US4298606A (en) 1974-12-19 1979-08-28 Thiazolylacetamido compounds
FR7924297A FR2468599B1 (en) 1974-12-19 1979-09-28 THIAZOLYLACETIC ACID DERIVATIVES AND PREPARATION METHOD
CH407680A CH633544A5 (en) 1974-12-19 1980-05-23 METHOD FOR PRODUCING THIAZOLIC ACID COMPOUNDS.
CH407580A CH628058A5 (en) 1974-12-19 1980-05-23 METHOD FOR PRODUCING CEPHEMIC COMPOUNDS.
NL8003054A NL8003054A (en) 1974-12-19 1980-05-27 ALFA-PROTECTED OXYIMINO BETA-OXO RANGE-HALOGEN-BUTIC ACID DERIVATIVES.
JP56087403A JPS5858353B2 (en) 1975-06-09 1981-06-05 Cefem or penam compound and its production method
HK22/82A HK2282A (en) 1975-06-09 1982-01-14 Cephem compounds
DK530282A DK155218C (en) 1974-12-19 1982-11-29 THIAZOLYLIC ACETIC ACID COMPOUNDS USED AS INTERMEDIATES IN THE PRODUCTION OF CEPHEM COMPOUNDS
MY219/82A MY8200219A (en) 1975-06-09 1982-12-30 Cephem compounds
JP58012560A JPS58185553A (en) 1975-06-09 1983-01-27 Alpha-protected oxyimino-beta-keto-gamma-halogenobutyric acid
US06/525,663 US4514565A (en) 1974-12-19 1983-06-24 Thiazolylacetamido cephalosphorin compounds
JP58178160A JPS5989686A (en) 1975-06-09 1983-09-28 Cephem or penam compound
JP60232072A JPS61143388A (en) 1975-06-09 1985-10-16 Cephem compound
US06/824,578 US4668783A (en) 1974-12-19 1986-01-23 Thiazolylacetamido cephalosporin compounds
US07/203,410 US4973684A (en) 1974-12-19 1988-06-07 Cephem compounds
US07/203,409 US4912212A (en) 1974-12-19 1988-06-07 Cephem compounds
US07/462,492 US5583216A (en) 1974-12-19 1990-01-08 Methods for the manufacture of cephems
BG98461A BG60437B2 (en) 1974-12-19 1994-02-11 Thiasolylacetamides
NL950016C NL950016I1 (en) 1974-12-19 1995-08-22 A method of preparing pharmaceutical preparations with antibiotic activity, as well as a method of preparing antibiotic active cephem compounds.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB24611/75A GB1536281A (en) 1975-06-09 1975-06-09 Cephem compounds

Publications (1)

Publication Number Publication Date
GB1536281A true GB1536281A (en) 1978-12-20

Family

ID=10214399

Family Applications (1)

Application Number Title Priority Date Filing Date
GB24611/75A Expired GB1536281A (en) 1974-12-19 1975-06-09 Cephem compounds

Country Status (7)

Country Link
JP (5) JPS5822039B2 (en)
AT (2) AT344894B (en)
GB (1) GB1536281A (en)
HK (1) HK2282A (en)
HU (1) HU172304B (en)
MY (1) MY8200219A (en)
SE (1) SE444809B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2117770A (en) * 1982-03-29 1983-10-19 Bristol Myers Co Cephalosporin derivatives
EP0096903A2 (en) * 1980-03-06 1983-12-28 Fujisawa Pharmaceutical Co., Ltd. Intermediate compounds for preparing cephem compounds and processes for their preparation
EP0097961A2 (en) 1982-06-28 1984-01-11 Bristol-Myers Company Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
US4598075A (en) * 1982-08-07 1986-07-01 Tanabe Seiyaku Co., Ltd. Cephalosporin compounds
US4816452A (en) * 1985-07-25 1989-03-28 Beecham Group P.L.C. Aminothiazole substituted penicillins and antibacterial compositions thereof
US4912212A (en) * 1974-12-19 1990-03-27 Takeda Chemical Industries, Ltd. Cephem compounds

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
FR2346014A1 (en) * 1976-01-23 1977-10-28 Roussel Uclaf Amino-thiazolyl-hydroxyimino-acetamido-cephalosporanic acids - with antibacterial activity
SE440655B (en) * 1976-01-23 1985-08-12 Roussel Uclaf SET TO MAKE NEW OXIME DERIVATIVES OF 7-AMINO-THIAZOLYL-ACETAMIDO-CEPHALOSPORANIC ACID
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
FI771866A (en) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
AU520269B2 (en) * 1977-03-14 1982-01-21 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
JPS5444695A (en) * 1977-09-13 1979-04-09 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid and its salt and their preparation
FR2410655A1 (en) * 1977-12-05 1979-06-29 Roussel Uclaf NEW OXIMES DERIVED FROM 3-SUBSTITUTE 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC, THEIR METHOD OF PREPARATION AND THEIR APPLICATION AS MEDICINAL PRODUCTS
DE2758001A1 (en) * 1977-12-24 1979-07-12 Hoechst Ag CEPHALOSPORINE DERIVATIVES AND METHOD FOR THEIR PRODUCTION
FR2387235A1 (en) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF COMPOUNDS OF 3,7-DISUBSTITUE-3-CEPHEM-4-CARBOXYLIC ACID AND NEW PRODUCTS THUS OBTAINED, HAVING A STRONG ANTIBACTERIAL ACTIVITY
JPS54106495A (en) * 1978-02-09 1979-08-21 Dai Ichi Seiyaku Co Ltd Cephem derivative
JPS54128594A (en) * 1978-03-27 1979-10-05 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acid derivative
FR2432521A1 (en) * 1978-03-31 1980-02-29 Roussel Uclaf NOVEL O-SUBSTITUTED OXIMES DERIVED FROM 7-AMINO THIAZOLYL ACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION PROCESS AND THEIR USE AS MEDICAMENTS
DE2818263A1 (en) * 1978-04-26 1979-11-08 Bayer Ag BETA LACTAMANTIBIOTICS
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
BE878637A (en) * 1978-09-11 1980-03-06 Fujisawa Pharmaceutical Co PROCESS FOR THE PREPARATION OF 3,7-DISUBSTITUTED 3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, NOVEL PRODUCTS THUS OBTAINED AND THEIR USE FOR THEIR ANTIMICROBIAL ACTIVITIES
JPS5543089A (en) * 1978-09-12 1980-03-26 Fujisawa Pharmaceut Co Ltd Preparation of 3-cephem compound
JPS5594354A (en) * 1979-01-12 1980-07-17 Fujisawa Pharmaceut Co Ltd Syn-isomer of 2-substituted imino-3-oxo-4-halobutyric acid, its salt, and their preparation
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
JPS6150973A (en) * 1983-11-16 1986-03-13 Fujisawa Pharmaceut Co Ltd Substituted iminoacetic acid derivative and salt and preparation thereof
IT1180207B (en) * 1984-07-30 1987-09-23 Istituto Biochimico Italiano PROCEDURE FOR THE PREPARATION, WITH HIGH YIELD AND PURITY, OF BETA-LACTAMIC ANTIBIOTICS
JPS60155167A (en) * 1984-07-31 1985-08-15 Fujisawa Pharmaceut Co Ltd Substituted iminoacetic acid derivative and its salt
JPS61121746U (en) * 1985-01-16 1986-07-31
GB8519606D0 (en) * 1985-08-05 1985-09-11 Fujisawa Pharmaceutical Co 3 7-d substituted-3-cephem compounds
WO1988005776A1 (en) * 1987-02-02 1988-08-11 Teijin Limited Cephalosporin compounds or their salts, process for their preparation, and parmaceutical compositions
WO1988005777A1 (en) * 1987-02-03 1988-08-11 Teijin Limited Cephalosporin compounds or their salts, process for their preparation, and pharmaceutical compositions
JPH02281051A (en) * 1989-04-21 1990-11-16 Toyo Tire & Rubber Co Ltd Tread rubber composition for tire
JPH09110877A (en) 1995-10-17 1997-04-28 Katayama Seiyakushiyo:Kk Cephem compound, its production and antibacterial agent containing the compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912212A (en) * 1974-12-19 1990-03-27 Takeda Chemical Industries, Ltd. Cephem compounds
US4973684A (en) * 1974-12-19 1990-11-27 Takeda Chemical Industries, Ltd. Cephem compounds
EP0096903A2 (en) * 1980-03-06 1983-12-28 Fujisawa Pharmaceutical Co., Ltd. Intermediate compounds for preparing cephem compounds and processes for their preparation
EP0096903A3 (en) * 1980-03-06 1984-02-01 Fujisawa Pharmaceutical Co., Ltd. Intermediate compounds for preparing cephem compounds and processes for their preparation
GB2117770A (en) * 1982-03-29 1983-10-19 Bristol Myers Co Cephalosporin derivatives
EP0097961A2 (en) 1982-06-28 1984-01-11 Bristol-Myers Company Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
US4598075A (en) * 1982-08-07 1986-07-01 Tanabe Seiyaku Co., Ltd. Cephalosporin compounds
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ATA517177A (en) 1978-05-15
JPS61143388A (en) 1986-07-01
JPS6155905B2 (en) 1986-11-29
MY8200219A (en) 1982-12-31
HK2282A (en) 1982-01-22
JPS5756485A (en) 1982-04-05
SE7713233L (en) 1977-11-23
SE444809B (en) 1986-05-12
AT347587B (en) 1979-01-10
JPS5822039B2 (en) 1983-05-06
JPH0346474B2 (en) 1991-07-16
HU172304B (en) 1978-07-28
JPS58185553A (en) 1983-10-29
JPS5858353B2 (en) 1983-12-24
JPS5989686A (en) 1984-05-23
AT344894B (en) 1978-08-10
JPS51149296A (en) 1976-12-22
ATA967775A (en) 1977-12-15

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