JPS54128594A - 3,7-disubstituted-3-cephem-4-carboxylic acid derivative - Google Patents

3,7-disubstituted-3-cephem-4-carboxylic acid derivative

Info

Publication number
JPS54128594A
JPS54128594A JP3559078A JP3559078A JPS54128594A JP S54128594 A JPS54128594 A JP S54128594A JP 3559078 A JP3559078 A JP 3559078A JP 3559078 A JP3559078 A JP 3559078A JP S54128594 A JPS54128594 A JP S54128594A
Authority
JP
Japan
Prior art keywords
formula
compound
cephem
disubstituted
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3559078A
Other languages
Japanese (ja)
Inventor
Takao Takatani
Takashi Ogino
Takashi Masugi
Kiryo Tsuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP3559078A priority Critical patent/JPS54128594A/en
Publication of JPS54128594A publication Critical patent/JPS54128594A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula I: [R1 is group of formula II or III (X is S, O, imino, acylimino), etc,; R2 is H or lower alkyl group; R3 is acyloxy or heterocyclic thio group which may be substituted] and its salt.
EXAMPLE: 7-[2-(2,3-Dihydro-1,4-oxathiin-6-yl)-2-methoxyiminoacetamido]cephalosporanic acid.
USE: Antibacterials having a wide range of antibacterial spectrum.
PROCESS: A compound of formula IV or its salt is reacted with a novel compound of formula V in a solvent, e.g. water or acetone, if necessary, in the presence of a condensing agent, e.g. a Vilsmeier reagent, to give a compound of formula I. The compound of formula V is obtained by reacting a compound of the formula HSCH2CH2-X-H with a compound of formula VI: (Hal is halogen; R4 is lower alkyl group), and by hydrolyzing the reaction product.
COPYRIGHT: (C)1979,JPO&Japio
JP3559078A 1978-03-27 1978-03-27 3,7-disubstituted-3-cephem-4-carboxylic acid derivative Pending JPS54128594A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3559078A JPS54128594A (en) 1978-03-27 1978-03-27 3,7-disubstituted-3-cephem-4-carboxylic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3559078A JPS54128594A (en) 1978-03-27 1978-03-27 3,7-disubstituted-3-cephem-4-carboxylic acid derivative

Publications (1)

Publication Number Publication Date
JPS54128594A true JPS54128594A (en) 1979-10-05

Family

ID=12445994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3559078A Pending JPS54128594A (en) 1978-03-27 1978-03-27 3,7-disubstituted-3-cephem-4-carboxylic acid derivative

Country Status (1)

Country Link
JP (1) JPS54128594A (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51149296A (en) * 1975-06-09 1976-12-22 Takeda Chem Ind Ltd Cephems or penams and their preparation
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS6133035A (en) * 1984-07-25 1986-02-15 Nec Corp Circuit test system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51149296A (en) * 1975-06-09 1976-12-22 Takeda Chem Ind Ltd Cephems or penams and their preparation
JPS52125190A (en) * 1976-04-12 1977-10-20 Fujisawa Pharmaceut Co Ltd 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation
JPS6133035A (en) * 1984-07-25 1986-02-15 Nec Corp Circuit test system

Similar Documents

Publication Publication Date Title
JPS5498795A (en) Cephalosporin derivative and its preparation
JPS56131565A (en) 4-substituted-2-oxoazetidine compound and its preparation
JPS5547688A (en) Novel cephem compound and its preparation
ATE53034T1 (en) PROCESS FOR THE PREPARATION OF CEPHEM COMPOUNDS.
SE7907320L (en) 3,7-DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDS AND PROCEDURES FOR THEIR PREPARATION
JPS54128594A (en) 3,7-disubstituted-3-cephem-4-carboxylic acid derivative
JPS54128591A (en) Cephalosporin analog
SE7901262L (en) 3,7-DISUBSTITUTED 3-CEFEM-4-CARBOXYLIC ACID COMPOUNDS AND PROCEDURES FOR THEIR PREPARATION
JPS56108794A (en) Preparation of 7-amino-3-thiadiazolylthiomethyl-3-cephem- 4-carboxylic acid derivative
JPS55129287A (en) Imidazole-dicarboxylic acid derivative
US4107179A (en) Method for preparing ticrynafen
JPS5754177A (en) Substituted thiazole derivative
JPS5515454A (en) Novel cephalosporin derivative
KR810000198B1 (en) Method for preparing ticrynafen
JPS57106663A (en) 1,4-disubstituted piperazine derivative and its preparation
JPS55139387A (en) Novel synthetic method of 7-amino-3-heterocyclic thiomethyl-delta3-carboxylic acids
JPS57106684A (en) Syn-isomer of 7-substituted-3-cephem-4-carboxylic acid ester and its preparation
JPS54106495A (en) Cephem derivative
JPS55143982A (en) Thiophene derivative
JPS5649387A (en) Novel cephem compound, its preparation, and remedy and preventive for microbism
JPS5527111A (en) Preparation of cephapirin
JPS57163386A (en) Cephalosporin derivative and its production
JPS5772988A (en) Production of novel cephalosporin derivaive
JPS5581882A (en) Preparation of hexahydronaphtho(1,2':4,5)imidazo(2,1-b)thiazole derivative
JPS56122353A (en) Pyridinol derivative and its preparation