JPS54128594A - 3,7-disubstituted-3-cephem-4-carboxylic acid derivative - Google Patents
3,7-disubstituted-3-cephem-4-carboxylic acid derivativeInfo
- Publication number
- JPS54128594A JPS54128594A JP3559078A JP3559078A JPS54128594A JP S54128594 A JPS54128594 A JP S54128594A JP 3559078 A JP3559078 A JP 3559078A JP 3559078 A JP3559078 A JP 3559078A JP S54128594 A JPS54128594 A JP S54128594A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- cephem
- disubstituted
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula I: [R1 is group of formula II or III (X is S, O, imino, acylimino), etc,; R2 is H or lower alkyl group; R3 is acyloxy or heterocyclic thio group which may be substituted] and its salt.
EXAMPLE: 7-[2-(2,3-Dihydro-1,4-oxathiin-6-yl)-2-methoxyiminoacetamido]cephalosporanic acid.
USE: Antibacterials having a wide range of antibacterial spectrum.
PROCESS: A compound of formula IV or its salt is reacted with a novel compound of formula V in a solvent, e.g. water or acetone, if necessary, in the presence of a condensing agent, e.g. a Vilsmeier reagent, to give a compound of formula I. The compound of formula V is obtained by reacting a compound of the formula HSCH2CH2-X-H with a compound of formula VI: (Hal is halogen; R4 is lower alkyl group), and by hydrolyzing the reaction product.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3559078A JPS54128594A (en) | 1978-03-27 | 1978-03-27 | 3,7-disubstituted-3-cephem-4-carboxylic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3559078A JPS54128594A (en) | 1978-03-27 | 1978-03-27 | 3,7-disubstituted-3-cephem-4-carboxylic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54128594A true JPS54128594A (en) | 1979-10-05 |
Family
ID=12445994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3559078A Pending JPS54128594A (en) | 1978-03-27 | 1978-03-27 | 3,7-disubstituted-3-cephem-4-carboxylic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54128594A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51149296A (en) * | 1975-06-09 | 1976-12-22 | Takeda Chem Ind Ltd | Cephems or penams and their preparation |
JPS52125190A (en) * | 1976-04-12 | 1977-10-20 | Fujisawa Pharmaceut Co Ltd | 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation |
JPS6133035A (en) * | 1984-07-25 | 1986-02-15 | Nec Corp | Circuit test system |
-
1978
- 1978-03-27 JP JP3559078A patent/JPS54128594A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51149296A (en) * | 1975-06-09 | 1976-12-22 | Takeda Chem Ind Ltd | Cephems or penams and their preparation |
JPS52125190A (en) * | 1976-04-12 | 1977-10-20 | Fujisawa Pharmaceut Co Ltd | 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation |
JPS6133035A (en) * | 1984-07-25 | 1986-02-15 | Nec Corp | Circuit test system |
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